Search Results - "HIGASHIYAMA, Masahiko"

Intratumor heterogeneity of epidermal growth factor receptor mutations in lung cancer and its correlation to the response to gefitinib by Taniguchi, Kazuya, Okami, Jiro, Kodama, Ken, Higashiyama, Masahiko, Kato, Kikuya

“…Somatic mutations introduced into the epidermal growth factor receptor (EGFR) gene in non‐small‐cell lung cancer (NSCLC) are important factors to determine…”
Get full text

Oncologic Outcomes of Segmentectomy Versus Lobectomy for Clinical T1a N0 M0 Non-Small Cell Lung Cancer by Kodama, Ken, MD, Higashiyama, Masahiko, MD, Okami, Jiro, MD, Tokunaga, Toshiteru, MD, Imamura, Fumio, MD, Nakayama, Tomio, MD, Inoue, Atsuo, MD, Kuriyama, Keiko, MD

“…Background We retrospectively compared the oncologic outcome after segmentectomy versus lobectomy in patients with clinical (c-) T1a N0 M0 non-small cell lung…”
Get full text

Quantitative Detection of EGFR Mutations in Circulating Tumor DNA Derived from Lung Adenocarcinomas by TANIGUCHI, Kazuya, UCHIDA, Junji, NISHINO, Kazumi, KUMAGAI, Toru, OKUYAMA, Takako, OKAMI, Jiro, HIGASHIYAMA, Masahiko, KODAMA, Ken, IMAMURA, Fumio, KATO, Kikuya

“…Examination of somatic epidermal growth factor receptor (EGFR) mutations is now a diagnostic routine for treatment of cancer using EGFR tyrosine kinase…”
Get full text

Surgical Outcome and Prognostic Stratification for Pulmonary Metastasis from Colorectal Cancer by Okumura, Takehiro, MD, Boku, Narikazu, MD, PhD, Hishida, Tomoyuki, MD, Ohde, Yasuhisa, MD, Sakao, Yukinori, MD, Yoshiya, Katsuo, MD, Higashiyama, Masahiko, MD, PhD, Hyodo, Ichinosuke, MD, PhD, Mori, Keita, PhD, Kondo, Haruhiko, MD

“…Background This study investigated recent clinical outcomes and prognostic factors of metastasectomy for pulmonary metastasis (PM) from colorectal cancer…”
Get full text

Radical sublobar resection for small-sized non–small cell lung cancer: A multicenter study by Okada, Morihito, Koike, Teruaki, Higashiyama, Masahiko, Yamato, Yasushi, Kodama, Ken, Tsubota, Noriaki

“…At present, even when early-stage, small-sized non–small cell lung cancers are being increasingly detected, lesser resection has not become the treatment of…”
Get full text

Leveraging fine-mapping and multipopulation training data to improve cross-population polygenic risk scores by Weissbrod, Omer, Kanai, Masahiro, Shi, Huwenbo, Gazal, Steven, Peyrot, Wouter J., Khera, Amit V., Okada, Yukinori, Martin, Alicia R., Finucane, Hilary K., Price, Alkes L.

“…Polygenic risk scores suffer reduced accuracy in non-European populations, exacerbating health disparities. We propose PolyPred, a method that improves…”
Get full text

Video-Assisted Thoracic Surgery Thymectomy Versus Sternotomy Thymectomy in Patients With Thymoma by Agatsuma, Hiroyuki, MD, Yoshida, Kazuo, MD, PhD, Yoshino, Ichiro, MD, PhD, Okumura, Meinoshin, MD, PhD, Higashiyama, Masahiko, MD, PhD, Suzuki, Kenji, MD, PhD, Tsuchida, Masanori, MD, PhD, Usuda, Jitsuo, MD, PhD, Niwa, Hiroshi, MD, PhD

“…Background This study was designed to evaluate the feasibility of video-assisted thoracoscopic surgery (VATS) and to compare the oncologic outcomes of VATS…”
Get full text

Plasma free amino acid profiling of five types of cancer patients and its application for early detection by Miyagi, Yohei, Higashiyama, Masahiko, Gochi, Akira, Akaike, Makoto, Ishikawa, Takashi, Miura, Takeshi, Saruki, Nobuhiro, Bando, Etsuro, Kimura, Hideki, Imamura, Fumio, Moriyama, Masatoshi, Ikeda, Ichiro, Chiba, Akihiko, Oshita, Fumihiro, Imaizumi, Akira, Yamamoto, Hiroshi, Miyano, Hiroshi, Horimoto, Katsuhisa, Tochikubo, Osamu, Mitsushima, Toru, Yamakado, Minoru, Okamoto, Naoyuki

“…Recently, rapid advances have been made in metabolomics-based, easy-to-use early cancer detection methods using blood samples. Among metabolites, profiling of…”
Get full text

Possibility of multivariate function composed of plasma amino acid profiles as a novel screening index for non-small cell lung cancer: a case control study by Maeda, Jun, Higashiyama, Masahiko, Imaizumi, Akira, Nakayama, Tomio, Yamamoto, Hiroshi, Daimon, Takashi, Yamakado, Minoru, Imamura, Fumio, Kodama, Ken

“…The amino-acid balance in cancer patients often differs from that in healthy individuals, because of metabolic changes. This study investigated the use of…”
Get full text

The Impact of Kinlessness on Survival in Patients With Advanced Non-small Cell Lung Cancer: A Single-Center Retrospective Study by Omura, Akiisa, Nojiri, Takashi, Higashiyama, Masahiko

“…Objectives Among patients with advanced non-small cell lung cancer (NSCLC), there are those who do not have a spouse, family members, or friends to support…”
Get full text

Pulmonary metastasectomy: outcomes and issues according to the type of surgical resection by Higashiyama, Masahiko, Tokunaga, Toshiteru, Nakagiri, Tomoyuki, Ishida, Daisuke, Kuno, Hidenori, Okami, Jiro

“…According to a recent report by the Committee for Scientific Affairs of the Japanese Association for Thoracic Surgery, pulmonary metastasectomy accounted for…”
Get full text

Different spatial distributions of brain metastases from lung cancer by histological subtype and mutation status of epidermal growth factor receptor by Takano, Koji, Kinoshita, Manabu, Takagaki, Masatoshi, Sakai, Mio, Tateishi, Souichirou, Achiha, Takamune, Hirayama, Ryuichi, Nishino, Kazumi, Uchida, Junji, Kumagai, Toru, Okami, Jiro, Kawaguchi, Atsushi, Hashimoto, Naoya, Nakanishi, Katsuyuki, Imamura, Fumio, Higashiyama, Masahiko, Yoshimine, Toshiki

“…The purpose of this study was to test the hypothesis that the genetic backgrounds of lung cancers could affect the spatial distribution of brain metastases. CT…”
Get full text

Phase III study of adjuvant gemcitabine compared with adjuvant uracil-tegafur in patients with completely resected pathological stage IB–IIIA non-small cell lung cancer (WJTOG0101) by Yamaguchi, Masafumi, Tada, Hirohito, Mitsudomi, Tetsuya, Seto, Takashi, Yokoi, Kohei, Katakami, Nobuyuki, Nakagawa, Kazuhiko, Oda, Makoto, Ohta, Mitsunori, Sawa, Toshiyuki, Yamashita, Motohiro, Iked, Norihiko, Saka, Hideo, Higashiyama, Masahiko, Nomori, Hiroaki, Semba, Hiroshi, Negoro, Shunichi, Chiba, Yasutaka, Shimokawa, Mototsugu, Fukuoka, Masahiro, Nakanishi, Yoichi

“…Background Adjuvant oral uracil-tegafur (UFT) has led to significantly longer postoperative survival among patients with non-small-cell lung cancer (NSCLC)…”
Get full text

Long-term survival in thymic carcinoma with postoperative pleural dissemination by Kimura, Toru, Higashiyama, Masahiko, Honma, Keiichiro, Nakamura, Harumi, Maniwa, Tomohiro, Okami, Jiro

“…Background We report a patient with thymic squamous cell carcinoma who underwent multiple rounds of surgical resection and definitive radiotherapy for both…”
Get full text

Number of metastatic lymph nodes and zones as prognostic factors in non-small-cell lung cancer by Maniwa, Tomohiro, Ohmura, Akiisa, Hiroshima, Takashi, Ike, Akihiro, Kimura, Toru, Nakamura, Harumi, Nakatsuka, Shin-Ichi, Okami, Jiro, Higashiyama, Masahiko

“…Abstract OBJECTIVES Characterizing pathological nodes (pNs) by location alone is sometimes inadequate as patients with pN1 or pN2 non-small-cell lung cancer…”
Get full text

Sublobar Resection Provides an Equivalent Survival After Lobectomy in Elderly Patients With Early Lung Cancer by Okami, Jiro, MD, PhD, Ito, Yuri, PhD, Higashiyama, Masahiko, MD, PhD, Nakayama, Tomio, MD, PhD, Tokunaga, Toshiteru, MD, PhD, Maeda, Jun, MD, PhD, Kodama, Ken, MD, PhD

“…Background Sublobar resection is indicated for early-stage non-small cell lung cancer in patients with a perioperative risk associated with impaired medical…”
Get full text

Preoperative AminoIndex Cancer Screening (AICS) abnormalities predict postoperative recurrence in patients undergoing curative resection for non-small cell lung cancer by Higashiyama, Masahiko, Miyazaki, Ryohei, Yamamoto, Hiroshi, Anayama, Takashi, Kikuchi, Shinya, Hirohashi, Kentaro, Okami, Jiro, Maniwa, Tomohiro, Kimura, Toru, Orihashi, Kazumasa, Imamura, Fumio

“…AminoIndex™ Cancer Screening (AICS (lung)) was developed as a screening test for lung cancer using a multivariate analysis of plasma-free amino acid (PFAA)…”
Get full text

Long-term results of surgical resection for pulmonary metastasis from renal cell carcinoma: a 25-year single-institution experience by Kanzaki, Ryu, Higashiyama, Masahiko, Fujiwara, Ayako, Tokunaga, Toshiteru, Maeda, Jun, Okami, Jiro, Nishimura, Kazuo, Kodama, Ken

“…Abstract Objective: Despite the report of new treatment options, surgery remains the best treatment for pulmonary metastases from renal cell carcinoma (RCC)…”
Get full text

Thymoma Patients With Pleural Dissemination: Nationwide Retrospective Study of 136 Cases in Japan by Okuda, Katsuhiro, MD, PhD, Yano, Motoki, MD, PhD, Yoshino, Ichiro, MD, PhD, Okumura, Meinoshin, MD, PhD, Higashiyama, Masahiko, MD, PhD, Suzuki, Kenji, MD, PhD, Tsuchida, Masanori, MD, PhD, Usuda, Jitsuo, MD, PhD, Tateyama, Hisashi, MD, PhD

“…Background Thymoma is a rare mediastinal tumor with relatively slow growth. However, advanced-stage cases with pleural dissemination are occasionally…”
Get full text

Occult mediastinal lymph node metastasis in NSCLC patients diagnosed as clinical N0-1 by preoperative integrated FDG-PET/CT and CT: Risk factors, pattern, and histopathological study by Kanzaki, Ryu, Higashiyama, Masahiko, Fujiwara, Ayako, Tokunaga, Toshiteru, Maeda, Jun, Okami, Jiro, Kozuka, Takenori, Hosoki, Takuya, Hasegawa, Yoshihisa, Takami, Motohisa, Tomita, Yasuhiko, Kodama, Ken

“…Abstract Background Integrated F18-fluorodeoxyglucose positron emission tomography/computed tomography (FDG-PET/CT) is widely used for mediastinal lymph node…”
Get full text