Search Results - "HEYNS, W"

A Sertoli Cell-Selective Knockout of the Androgen Receptor Causes Spermatogenic Arrest in Meiosis by De Gendt, Karel, Swinnen, Johannes V., Philippa T. K. Saunders, Schoonjans, Luc, Dewerchin, Mieke, Devos, Ann, Tan, Karen, Atanassova, Nina, Claessens, Frank, Lécureuil, Charlotte, Heyns, Walter, Carmeliet, Peter, Guillou, Florian, Sharpe, Richard M., Verhoeven, Guido

“…Androgens control spermatogenesis, but germ cells themselves do not express a functional androgen receptor (AR). Androgen regulation is thought to be mediated…”
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The retinoblastoma protein-associated transcription repressor RBaK interacts with the androgen receptor and enhances its transcriptional activity by Hofman, K, Swinnen, JV, Claessens, F, Verhoeven, G, Heyns, W

“…In search of potential androgen receptor coregulators we performed a yeast two-hybrid screening using the androgen receptor ligand-binding domain as bait and a…”
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Androgens transcriptionally regulate the expression of cystatin-related protein and the C3 component of prostatic binding protein in rat ventral prostate and lacrimal gland by Vercaeren, I, Vanaken, H, Devos, A, Peeters, B, Verhoeven, G, Heyns, W

“…In this report, it is demonstrated that the C3 component of prostatic binding protein (PBP) is also expressed and androgen regulated in the exorbital lacrimal…”
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Functional characterization of an androgen response element in the first intron of the C3(1) gene of prostatic binding protein by Claessens, F, Celis, L, Peeters, B, Heyns, W, Verhoeven, G, Rombauts, W

“…We demonstrate that the 204 bp intronic gene fragment of C3(1), which has a specific in vitro affinity for the androgen receptor, is able to confer androgen…”
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Identification of a Functional Androgen-Response Element in the Exon 1-Coding Sequence of the Cystatin-Related Protein Gene crp2 by Devos, A, Claessens, F, Alen, P, Winderickx, J, Heyns, W, Rombauts, W, Peeters, B

“…Two hormone-responsive segments, one in the region of the promoter and one in intron 1, are identified in two homologous androgen-regulated and differentially…”
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Interaction of the 90-kDa heat shock protein with native and in vitro translated androgen receptor and receptor fragments by Marivoet, S, Van Dijck, P, Verhoeven, G, Heyns, W

“…Androgen receptor (AR) from rat ventral prostate and AR synthesized in vitro by translation in rabbit reticulocyte lysate of AR mRNA, transcribed from a…”
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Triiodothyronine modulates growth, secretory function and androgen receptor concentration in the prostatic carcinoma cell line LNCaP by Esquenet, M., Swinnen, J.V., Heyns, W., Verhoeven, G.

“…There is increasing evidence that the course of prostatic carcinoma is determined by a complex interplay between genetic events, paracrine interactions, and…”
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Proteins interacting with an androgen-responsive unit in the C3(1) gene intron by Celis, L, Claessens, F, Peeters, B, Heyns, W, Verhoeven, G, Rombauts, W

“…The expression of the three genes encoding the components C1, C2 and C3 of prostatic binding protein (PBP) is under androgen control and restricted to the rat…”
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Occult ectopic ACTH secretion due to recurrent lung carcinoid: long‐term control of hypercortisolism by continuous subcutaneous infusion of octreotide by VAN DEN BRUEL, A, BEX, M, VAN DORPE, J, HEYNS, W, BOUILLON, R

“…We report on a woman with clinical Cushing's syndrome confirmed by biochemical data. The Cushing's syndrome was shown to be ACTH dependent and inferior…”
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Androgenic induction of cystatin-related protein and the C3 component of prostatic binding protein in primary cultures from the rat lacrimal gland by Vanaken, H, Claessens, F, Vercaeren, I, Heyns, W, Peeters, B, Rombauts, W

“…Cystatin-related protein (CRP) and the C3 component of prostatic binding protein (C3) are synthesized in vivo under androgen control in the lacrimal gland and…”
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Homologous radioimmunoassay of human osteocalcin by Bouillon, R, Vanderschueren, D, Van Herck, E, Nielsen, H K, Bex, M, Heyns, W, Van Baelen, H

“…Osteocalcin or bone gamma-glutamic acid-containing protein (GLA protein) was isolated from human bone and used to develop a homologous radioimmunoassay of…”
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Expression of cystatin-related protein and of the C3-component of prostatic-binding protein during postnatal development in the rat ventral prostate and lacrimal gland by Vercaeren, I, Vanaken, H, Van Dorpe, J, Verhoeven, G, Heyns, W

“…The expression of cystatin-related protein (CRP) and of the C3-component of prostatic-binding protein (PBP) during postnatal development of the rat was studied…”
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Influence of the vitamin D-binding protein on the serum concentration of 1,25-dihydroxyvitamin D3. Significance of the free 1,25-dihydroxyvitamin D3 concentration by Bouillon, R, Van Assche, F A, Van Baelen, H, Heyns, W, De Moor, P

“…The influence of the serum binding protein (DBP) for vitamin D and its metabolites on the concentration of its main ligands, 25-hydroxyvitamin D(3) (25-OHD(3))…”
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Epigallocatechin‐3‐gallate is a potent natural inhibitor of fatty acid synthase in intact cells and selectively induces apoptosis in prostate cancer cells by Brusselmans, Koen, De Schrijver, Ellen, Heyns, Walter, Verhoeven, Guido, Swinnen, Johannes V.

“…Chemical inhibitors of fatty acid synthase (FAS) inhibit growth and induce apoptosis in several cancer cell lines in vitro and in tumor xenografts in vivo…”
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RNA interference-mediated silencing of the fatty acid synthase gene attenuates growth and induces morphological changes and apoptosis of LNCaP prostate cancer cells by DE SCHRIJVER, Ellen, BRUSSELMANS, Koen, HEYNS, Walter, VERHOEVEN, Guido, SWINNEN, Johannes V

“…Fatty acid synthase (FASE), a key enzyme in the biosynthesis of fatty acids, is markedly overexpressed in many human epithelial cancers, rendering it an…”
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Intronic androgen response elements of prostatic binding protein genes by Claessens, F, Celis, L, De Vos, P, Peeters, B, Heyns, W, Verhoeven, G, Rombauts, W

“…Transcription of the genes that code for the different components of Prostatic Binding Protein is dependent on androgens. DNA-cellulose competition assays have…”
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Interaction of androgen response elements with the DNA-binding domain of the rat androgen receptor expressed in Escherichia coli by De Vos, P, Claessens, F, Winderickx, J, Van Dijck, P, Celis, L, Peeters, B, Rombauts, W, Heyns, W, Verhoeven, G

“…A fragment of the rat androgen receptor (amino acids 533-637) containing the DNA-binding domain was produced in Escherichia coli as a fusion product with…”
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Propofol Anesthesia Does Not Inhibit Stimulation of Cortisol Synthesis by Van Hemelrijck, Jan, Weekers, Frank, Van Aken, Hugo, Bouillon, Roger, Heyns, Walter

“…Recent data suggest a negative effect of propofol anesthesia on cortisol secretion.The present study was designed to evaluate the effect of propofol anesthesia…”
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Immunocytochemical localization of seminal proteins in salivary and lacrimal glands of the rat by Aumüller, G, Arce, E A, Heyns, W, Vercaeren, I, Dammshäuser, I, Seitz, J

“…Antibodies against 10 different secretory proteins from the accessory sex glands of the male rat were used for immunohistochemical studies of salivary and…”
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Overexpression of fatty acid synthase is an early and common event in the development of prostate cancer by Swinnen, Johannes V., Roskams, Tania, Joniau, Steven, Van Poppel, Hein, Oyen, Raymond, Baert, Luc, Heyns, Walter, Verhoeven, Guido

“…The expression of fatty acid synthase (FAS), a key lipogenic enzyme and potential target for antineoplastic therapy, was analyzed in 87 frozen needle biopsies…”
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