Search Results - "HEWITT, JEFF"

Somatostatin receptor subtype expression and function in human vascular tissue by Curtis, S B, Hewitt, J, Yakubovitz, S, Anzarut, A, Hsiang, Y N, Buchan, A M

“…In animal models the somatostatin analog angiopeptin inhibits intimal hyperplasia by acting primarily through somatostatin receptor 2 (SSTR-2). However, the…”
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Regulation of granuloma formation via Myd88 and Nox2 in a model of pulmonary sarcoidosis (MPF5P.741) by Werner, Jessica, Escolero, Sylvia, Hewitt, Jeff, Mak, Tim, Eishi, Yoshinobu, Núñez, Gabriel

“…Sarcoidosis is characterized by non-caseating granulomas with an unknown etiology that present primarily in the lung. Propionibacterium acnes, an immunogenic…”
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Biomining with bacteriophage: Selectivity of displayed peptides for naturally occurring sphalerite and chalcopyrite by Curtis, Susan B, Hewitt, Jeff, MacGillivray, Ross T.A, Dunbar, W. Scott

“…During mineral processing, concentrates of sulfide minerals of economic interest are formed by froth flotation of fine ore particles. The method works well but…”
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Identification and Cloning of Novel Mutations In a Compound Heterozygous Factor V Deficient Patient by Talbot, Kimberley, Song, Jina, Eghdami, Lily, Tamura-Wells, Jessica, Hewitt, Jeff, Vickars, Linda, Carter, Cedric John, MacGillivray, Ross T.A., Pryzdial, Ed L.G.

“…Abstract 2210 Congenital factor V (FV) deficiency is a rare clotting disorder associated with mild to severe hemorrhagic symptoms and a prevalence of…”
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Novel Compound Heterozygous Factor V Deficiency with Severe Clinical Phenotype by Talbot, Kimberley, Song, Jina, Eghdami, Lily, Hewitt, Jeff, Carter, Cedric J., MacGillivray, Ross T.A., Pryzdial, Ed L.G.

“…Abstract 3490 Poster Board III-427 Congenital factor V (FV) deficiency is a rare clotting disorder associated with mild to severe hemorrhagic symptoms and a…”
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A novel compensating mechanism for homozygous coagulation factor V deficiency suggested by enhanced activated partial thromboplastin time after reconstitution with normal factor V by Talbot, Kimberley, Song, Jina, Hewitt, Jeff, Serrano, Katherine, Ho, Michael, Carter, Cedric J., MacGillivray, Ross T. A., Pryzdial, Edward L. G.

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Differential Effect of a His Tag at the N- and C-Termini:  Functional Studies with Recombinant Human Serum Transferrin by Mason, Anne B, He, Qing-Yu, Halbrooks, Peter J, Everse, Stephen J, Gumerov, Dmitry R, Kaltashov, Igor A, Smith, Valerie C, Hewitt, Jeff, MacGillivray, Ross T. A

“…Attachment of a cleavable hexa His tag is a common strategy for the production of recombinant proteins. Production of two recombinant nonglycosylated human…”
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Molecular determination of the breakpoints of a 161 556 bp deletion at chromosome 13q34 that presented as severe factor VII deficiency in a neonate by Hewitt, Jeff, Craven, Sharon J., Brown, Lindsay A., Bleackley, Mark R., Ballard, Jennifer N. M., Smith, Valerie C., Ofosu, Frederick A., Huntsman, David G., Wadsworth, Louis D., Wu, John K., MacGillivray, Ross T. A.

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Germline mutation identified after amplification of nuclear DNA from citrated plasma by Hewitt, Jeff, Wong, Ann Y.K., Wadsworth, Louis D., MacGillivray, Ross T.A.

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Engineering the Primary Substrate Specificity of Streptomyces griseus Trypsin by Page, Michael J, Wong, Sui-Lam, Hewitt, Jeff, Strynadka, Natalie C. J, MacGillivray, Ross T. A

“…Streptomyces griseus trypsin (SGT) was chosen as a model scaffold for the development of serine proteases with enhanced substrate specificity. Recombinant SGT…”
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Severe FVII deficiency caused by a new point mutation combined with a previously undetected gene deletion by Hewitt, Jeff, Ballard, Jennifer N. M., Nelson, Tanya N., Smith, Valerie C., Griffiths, Tanya A. M., Pritchard, Sheila, Wu, John K., Wadsworth, Louis D., Casey, Brett, MacGillivray, Ross T. A.

“…Summary A 3‐week‐old Caucasian female presented with severe unprovoked parenchymal cerebral haemorrhage. Her plasma factor VII (FVII) activity was <0·01…”
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Identification of the epitope of a monoclonal antibody that disrupts binding of human transferrin to the human transferrin receptor by M. Teh, Evelyn, Hewitt, Jeff, C. Ung, Karen, Briggs, Sara K., Mason, Anne B., MacGillivray, Ross T. A.

“…The molecular basis of the transferrin (TF)–transferrin receptor (TFR) interaction is not known. The C‐lobe of TF is required to facilitate binding to the TFR…”
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Cloning, mutagenesis, and structural analysis of human pancreatic α-amylase expressed in Pichia pastoris by RYDBERG, EDWIN H., SIDHU, GARY, VO, HUNG C., HEWITT, JEFF, CÔTÉ, HÉLÈNE C.F., WANG, YILI, NUMAO, SHIN, MacGILLIVRAY, ROSS T.A., OVERALL, CHRISTOPHER M., BRAYER, GARY D., WITHERS, STEPHEN G.

“…Human pancreatic α-amylase (HPA) was expressed in the methylotrophic yeast Pichia pastoris and two mutants (D197A and D197N) of a completely conserved active…”
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Confirmation of paternity suggests a new mutation in the factor VII gene: ‘Pater certus quouque est’ ‐ Response to Girolami et al by Hewitt, Jeff, Ballard, Jennifer N. M., Nelson, Tanya N., Smith, Valerie C., Griffiths, Tanya A. M., Pritchard, Sheila, Wu, John K., Wadsworth, Louis D., Casey, Brett, MacGillivray, Ross T. A.

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Canada Line's ground stability in EPBM: at January's British Tunnelling Society meeting, Jeff Hewitt SVP of Canada Line Rapid Transit Inc, Professor Dan Eisenstein of the University of Alberta, and Marco Moccichino of SELI contractors presented the challenges of EPBM tunnelling and the interaction on soil conditioning by Hewitt, Jeff, Eisenstein, Dan, Moccichino, Marco

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Effect of endothelial and adventitial injury on somatostatin receptor expression by Curtis, Susan B., Chen, Jerry C., Winkelaar, Gerritt, Turnbull, Robert G., Hewitt, Jeff, Buchan, Alison M.J., Hsiang, York N.

“…Background. The somatostatin analog, angiopeptin, inhibits intimal hyperplasia formation; although the specific somatostatin receptor (SSTR) subtypes…”
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Equus caballus gelsolin by Koepf, Edward K., Hewitt, Jeff, Vo, Hung, Macgillivray, Ross T. A., Burtnick, Leslie D.

“…We have generated and characterized the cDNA from equine smooth muscle that encodes gelsolin, an actin‐modulating protein. Overlapping cDNA clones synthesized…”
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Nucleotide sequence of the phosphotransacetylase gene of Escherichia coli strain K12 by Matsuyama, A, Yamamoto-Otake, H, Hewitt, J, MacGillivray, R T, Nakano, E

“…The phosphotransacetylase gene (pta) from Escherichia coli strain K-12 1100 was identified in a cloned fragment of chromosomal DNA (Yamamoto-Otake, H.,…”
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Equus caballus gelsolin cDNA sequence and protein structural implications by Koepf, E.K, Hewitt, J, Vo, H, MacGillivray, R.T.A, Burtnick, L.D

“…We have generated and characterized the cDNA from equine smooth muscle that encodes gelsolin, an actin-modulating protein. Overlapping cDNA clones synthesized…”
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A novel compensating mechanism for homozygous coagulation factor V deficiency suggested by enhanced activated partial thromboplastin time after reconstitution with normal factor V by Talbot, Kimberley, Song, Jina, Hewitt, Jeff, Serrano, Katherine, Ho, Michael, Carter, Cedric J, MacGillivray, Ross T A, Pryzdial, Edward L G

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