Search Results - "HEUSSER, Karsten"
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Cerebral blood flow autoregulation assessment by correlation analysis between mean arterial blood pressure and transcranial doppler sonography or near infrared spectroscopy is different: A pilot study
Published in PloS one (22-06-2023)“…Recently, cerebral autoregulation indices based on moving correlation indices between mean arterial pressure (MAP) and cerebral oximetry (NIRS, ORx) or…”
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Deciphering the neural signature of human cardiovascular regulation
Published in eLife (28-07-2020)“…Cardiovascular regulation is integral to life. Animal studies have identified both neural and endocrine pathways, by which the central nervous system adjusts…”
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Carotid Baroreceptor Stimulation, Sympathetic Activity, Baroreflex Function, and Blood Pressure in Hypertensive Patients
Published in Hypertension (Dallas, Tex. 1979) (01-03-2010)“…In animals, electric field stimulation of carotid baroreceptors elicits a depressor response through sympathetic inhibition. We tested the hypothesis that the…”
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Baroreflex Curve Fitting Using a WYSIWYG Boltzmann Sigmoidal Equation
Published in Frontiers in neuroscience (27-09-2021)“…Arterial baroreflex assessment using vasoactive substances enables investigators to collect data pairs over a wide range of blood pressures and reflex…”
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Limited evidence for sympathetic neural overactivation in older patients with type 2 diabetes mellitus
Published in Frontiers in neuroscience (12-01-2023)“…Mechanistic studies suggested that excess sympathetic activity promotes arterial hypertension while worsening insulin sensitivity. Older patients with type 2…”
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Endovascular baroreflex amplification and the effect on sympathetic nerve activity in patients with resistant hypertension: A proof-of-principle study
Published in PloS one (16-11-2021)“…First in human studies suggest that endovascular baroreflex amplification (EVBA) lowers blood pressure (BP). To explore potential mechanisms for BP reduction,…”
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Glucose-sensitive hypothalamic nuclei traced through functional magnetic resonance imaging
Published in Frontiers in neuroscience (11-12-2023)“…Hypothalamic glucose-sensitive neural circuits, which regulate energy metabolism and can contribute to diseases such as obesity and type 2 diabetes, have been…”
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Effects of short-term hypercaloric nutrition on orthostatic tolerance in healthy individuals: a randomized controlled crossover study
Published in Clinical autonomic research (01-12-2022)“…Reduced-caloric intake lowers blood pressure through sympathetic inhibition, and worsens orthostatic tolerance within days. Conversely, hypercaloric nutrition…”
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Effects of Prolonged Head-Down Bed Rest on Cardiac and Vascular Baroreceptor Modulation and Orthostatic Tolerance in Healthy Individuals
Published in Frontiers in physiology (23-08-2019)“…Orthostatic intolerance commonly occurs after prolonged bed rest, thus increasing the risk of syncope and falls. Baroreflex-mediated adjustments of heart rate…”
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Impact of Daily Lower-Body Negative Pressure or Cycling Followed by Venous Constrictive Thigh Cuffs on Bedrest-Induced Orthostatic Intolerance
Published in Journal of the American Heart Association (05-11-2024)“…Orthostatic intolerance occurs following immobilization in patients on Earth and in astronauts after spaceflight. Head-down tilt bedrest is a terrestrial model…”
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Real-Time Magnetic Resonance Imaging to Study Orthostatic Intolerance Mechanisms in Human Beings: Proof of Concept
Published in Journal of the American Heart Association (01-11-2022)“…Background Discerning the mechanisms driving orthostatic symptoms in human beings remains challenging. Therefore, we developed a novel approach combining…”
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Ultrafine particles and ozone perturb norepinephrine clearance rather than centrally generated sympathetic activity in humans
Published in Scientific reports (06-03-2019)“…Cardiovascular risk rapidly increased following exposure to air pollution. Changes in human autonomic regulation have been implicated based on epidemiological…”
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Cardiovascular Regulation During Apnea in Elite Divers
Published in Hypertension (Dallas, Tex. 1979) (01-04-2009)“…Involuntary apnea during sleep elicits sustained arterial hypertension through sympathetic activation; however, little is known about voluntary apnea,…”
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Novel Approach to Elucidate Human Baroreflex Regulation at the Brainstem Level: Pharmacological Testing During fMRI
Published in Frontiers in neuroscience (05-03-2019)“…Brainstem nuclei govern the arterial baroreflex, which is crucial for heart rate and blood pressure control. Yet, brainstem function is difficult to explore in…”
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Cardiac pacemaker channel (HCN4) inhibition and atrial arrhythmogenesis after releasing cardiac sympathetic activation
Published in Scientific reports (17-05-2018)“…Clinical trials and studies with ivabradine implicate cardiac pacemaker channels (HCN4) in the pathogenesis of atrial arrhythmias. Because acute changes in…”
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Cardiac and Vascular Sympathetic Baroreflex Control during Orthostatic Pre-Syncope
Published in Journal of clinical medicine (10-09-2019)“…We hypothesized that sympathetic baroreflex mediated uncoupling between neural sympathetic discharge pattern and arterial pressure (AP) fluctuations at 0.1 Hz…”
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Correction to: A 20-year evolution of cardiac performance in microgravity in a male astronaut
Published in Clinical autonomic research (01-02-2021)“…Unfortunately, the first name of 8th author was incorrectly published in the original publication…”
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A 20-year evolution of cardiac performance in microgravity in a male astronaut
Published in Clinical autonomic research (01-02-2021)Get full text
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Physiological phenomenology of neurally-mediated syncope with management implications
Published in PloS one (25-10-2011)“…Due to lack of efficacy in recent trials, current guidelines for the treatment of neurally-mediated (vasovagal) syncope do not promote cardiac pacemaker…”
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Influences of Gender on the Interaction between Sympathetic Nerve Traffic and Central Adiposity
Published in The journal of clinical endocrinology and metabolism (01-12-2008)“…Context: Sympathetic activation promotes insulin resistance and arterial hypertension with increasing adiposity. A difference in the relationship between…”
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