Search Results - "HEUSSEL, Claus Peter"

Potential of ChatGPT and GPT-4 for Data Mining of Free-Text CT Reports on Lung Cancer by Fink, Matthias A., Bischoff, Arved, Fink, Christoph A., Moll, Martin, Kroschke, Jonas, Dulz, Luca, Heußel, Claus Peter, Kauczor, Hans-Ulrich, Weber, Tim F.

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Fibroblast Activation Protein-Specific PET/CT Imaging in Fibrotic Interstitial Lung Diseases and Lung Cancer: A Translational Exploratory Study by Röhrich, Manuel, Leitz, Dominik, Glatting, Frederik M, Wefers, Annika K, Weinheimer, Oliver, Flechsig, Paul, Kahn, Nicolas, Mall, Marcus A, Giesel, Frederik L, Kratochwil, Clemens, Huber, Peter E, Deimling, Andreas von, Heußel, Claus Peter, Kauczor, Hans Ulrich, Kreuter, Michael, Haberkorn, Uwe

“…Interstitial lung diseases (ILDs) comprise over 200 parenchymal lung disorders. Among them, fibrosing ILDs, especially idiopathic pulmonary fibrosis, are…”
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Deciphering the immunosuppressive tumor microenvironment in ALK- and EGFR-positive lung adenocarcinoma by Budczies, Jan, Kirchner, Martina, Kluck, Klaus, Kazdal, Daniel, Glade, Julia, Allgäuer, Michael, Kriegsmann, Mark, Heußel, Claus-Peter, Herth, Felix J., Winter, Hauke, Meister, Michael, Muley, Thomas, Goldmann, Torsten, Fröhling, Stefan, Wermke, Martin, Waller, Cornelius F., Tufman, Amanda, Reck, Martin, Peters, Solange, Schirmacher, Peter, Thomas, Michael, Christopoulos, Petros, Stenzinger, Albrecht

“…Introduction The advent of immune checkpoint blockade (ICB) has led to significantly improved disease outcome in lung adenocarcinoma (ADC), but response of…”
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Overdiagnosis in lung cancer screening: Estimates from the German Lung Cancer Screening Intervention Trial by González Maldonado, Sandra, Motsch, Erna, Trotter, Anke, Kauczor, Hans‐Ulrich, Heussel, Claus‐Peter, Hermann, Silke, Zeissig, Sylke Ruth, Delorme, Stefan, Kaaks, Rudolf

“…Overdiagnosis is a major potential harm of lung cancer screening; knowing its potential magnitude helps to optimize screening eligibility criteria. The German…”
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Residual symptoms and lower lung function in patients recovering from SARS-CoV-2 infection by Trinkmann, Frederik, Müller, Michael, Reif, Alexandra, Kahn, Nicolas, Kreuter, Michael, Trudzinski, Franziska, Eichinger, Monika, Heussel, Claus-Peter, Herth, Felix J F

“…Initial reports of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection indicate only mild disease in 81% of symptomatic cases [1]. Nearly…”
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Voriconazole versus itraconazole for antifungal prophylaxis following allogeneic haematopoietic stem‐cell transplantation by Marks, David I., Pagliuca, Antonio, Kibbler, Christopher C., Glasmacher, Axel, Heussel, Claus‐Peter, Kantecki, Michal, Miller, Paul J.S., Ribaud, Patricia, Schlamm, Haran T., Solano, Carlos, Cook, Gordon

“…Summary Antifungal prophylaxis for allogeneic haematopoietic stem‐cell transplant (alloHCT) recipients should prevent invasive mould and yeast infections…”
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Combined targeted DNA and RNA sequencing of advanced NSCLC in routine molecular diagnostics: Analysis of the first 3,000 Heidelberg cases by Volckmar, Anna‐Lena, Leichsenring, Jonas, Kirchner, Martina, Christopoulos, Petros, Neumann, Olaf, Budczies, Jan, Morais de Oliveira, Cristiano Manuel, Rempel, Eugen, Buchhalter, Ivo, Brandt, Regine, Allgäuer, Michael, Talla, Suranand Babu, von Winterfeld, Moritz, Herpel, Esther, Goeppert, Benjamin, Lier, Amelie, Winter, Hauke, Brummer, Tilman, Fröhling, Stefan, Faehling, Martin, Fischer, Jürgen R., Heußel, Claus Peter, Herth, Felix, Lasitschka, Felix, Schirmacher, Peter, Thomas, Michael, Endris, Volker, Penzel, Roland, Stenzinger, Albrecht

“…Tyrosine kinase inhibitors currently confer the greatest survival gain for nonsmall cell lung cancer (NSCLC) patients with actionable genetic alterations…”
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Diagnosis of invasive fungal diseases in haematology and oncology: 2018 update of the recommendations of the infectious diseases working party of the German society for hematology and medical oncology (AGIHO) by Ruhnke, Markus, Behre, Gerhard, Buchheidt, Dieter, Christopeit, Maximilian, Hamprecht, Axel, Heinz, Werner, Heussel, Claus‐Peter, Horger, Marius, Kurzai, Oliver, Karthaus, Meinolf, Löffler, Jürgen, Maschmeyer, Georg, Penack, Olaf, Rieger, Christina, Rickerts, Volker, Ritter, Jörg, Schmidt‐Hieber, Martin, Schuelper, Nikolai, Schwartz, Stefan, Ullmann, Andrew, Vehreschild, Jörg Janne, Lilienfeld‐Toal, Marie, Weber, Thomas, Wolf, Hans H.

“…Summary Invasive fungal diseases (IFD) are a primary cause of morbidity and mortality in patients with haematological malignancies. These infections are mostly…”
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A gene expression signature associated with B cells predicts benefit from immune checkpoint blockade in lung adenocarcinoma by Budczies, Jan, Kirchner, Martina, Kluck, Klaus, Kazdal, Daniel, Glade, Julia, Allgäuer, Michael, Kriegsmann, Mark, Heußel, Claus-Peter, Herth, Felix J., Winter, Hauke, Meister, Michael, Muley, Thomas, Fröhling, Stefan, Peters, Solange, Seliger, Barbara, Schirmacher, Peter, Thomas, Michael, Christopoulos, Petros, Stenzinger, Albrecht

“…Immune checkpoint blockade (ICB) expands the therapeutic options for metastatic lung cancer nowadays representing a standard frontline strategy as monotherapy…”
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Transbronchial cryobiopsy increases diagnostic confidence in interstitial lung disease: a prospective multicentre trial by Hetzel, Jürgen, Wells, Athol U, Costabel, Ulrich, Colby, Thomas V, Walsh, Simon L F, Verschakelen, Johny, Cavazza, Alberto, Tomassetti, Sara, Ravaglia, Claudia, Böckeler, Michael, Spengler, Werner, Kreuter, Michael, Eberhardt, Ralf, Darwiche, Kaid, Torrego, Alfons, Pajares, Virginia, Muche, Rainer, Musterle, Regina, Horger, Marius, Fend, Falko, Warth, Arne, Heußel, Claus Peter, Piciucchi, Sara, Dubini, Alessandra, Theegarten, Dirk, Franquet, Tomas, Lerma, Enrique, Poletti, Venerino, Häntschel, Maik

“…The accurate diagnosis of individual interstitial lung diseases (ILD) is often challenging, but is a critical determinant of appropriate management. If a…”
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Asynchronous calibration of quantitative computed tomography bone mineral density assessment for opportunistic osteoporosis screening: phantom-based validation and parameter influence evaluation by Skornitzke, Stephan, Vats, Neha, Kopytova, Taisiya, Tong, Elizabeth Wai Yee, Hofbauer, Tobias, Weber, Tim Frederik, Rehnitz, Christoph, von Stackelberg, Oyunbileg, Maier-Hein, Klaus, Stiller, Wolfram, Biederer, Jürgen, Kauczor, Hans-Ulrich, Heußel, Claus-Peter, Wielpütz, Mark, Palm, Viktoria

“…Asynchronous calibration could allow opportunistic screening based on routine CT for early osteoporosis detection. In this phantom study, a bone mineral…”
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Multicenter Standardization of Phase‐Resolved Functional Lung MRI in Patients With Suspected Chronic Thromboembolic Pulmonary Hypertension by Moher Alsady, Tawfik, Voskrebenzev, Andreas, Behrendt, Lea, Olsson, Karen, Heußel, Claus Peter, Gruenig, Ekkehard, Gall, Henning, Ghofrani, Ardeschir, Roller, Fritz, Harth, Sebastian, Marshall, Helen, Hughes, Paul J.C., Wild, Jim, Swift, Andrew J., Kiely, David G., Behr, Jürgen, Dinkel, Julien, Beitzke, Dietrich, Lang, Irene M., Schmidt, Kai Helge, Kreitner, Karl Friedrich, Frauenfelder, Thomas, Ulrich, Silvia, Hamer, Okka W., Vogel‐Claussen, Jens

“…Background Detection of pulmonary perfusion defects is the recommended approach for diagnosing chronic thromboembolic pulmonary hypertension (CTEPH). This is…”
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Spatial profiling of the microenvironment reveals low intratumoral heterogeneity and STK11-associated immune evasion in therapy-naïve lung adenocarcinomas by Goldschmid, Hannah, Kluck, Klaus, Ball, Markus, Kirchner, Martina, Allgäuer, Michael, Winter, Hauke, Herth, Felix, Heußel, Claus-Peter, Pullamsetti, Soni Savai, Savai, Rajkumar, Yong, Timothy Tay Kwang, Schirmacher, Peter, Peters, Solange, Thomas, Michael, Christopoulos, Petros, Budczies, Jan, Stenzinger, Albrecht, Kazdal, Daniel

“…•Significant intertumoral heterogeneity of the immunologic microenvironment.•Low spatial intratumoral heterogeneity with relatively stable immunologic…”
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Oligoprogressive Non-Small-Cell Lung Cancer under Treatment with PD-(L)1 Inhibitors by Rheinheimer, Stephan, Heussel, Claus-Peter, Mayer, Philipp, Gaissmaier, Lena, Bozorgmehr, Farastuk, Winter, Hauke, Herth, Felix J, Muley, Thomas, Liersch, Stephan, Bischoff, Helge, Kriegsmann, Mark, El Shafie, Rami A, Stenzinger, Albrecht, Thomas, Michael, Kauczor, Hans-Ulrich, Christopoulos, Petros

“…Oligoprogression (OPD) of non-small-cell lung cancer (NSCLC) occurs in approximately half of patients under targeted compounds (TKI) and facilitates use of…”
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Analysis of rare fusions in NSCLC: Genomic architecture and clinical implications by Seker-Cin, Huriye, Tay, Timothy Kwang Yong, Kazdal, Daniel, Kluck, Klaus, Ball, Markus, Neumann, Olaf, Winter, Hauke, Herth, Felix, Heußel, Claus-Peter, Savai, Rajkumar, Schirmacher, Peter, Thomas, Michael, Budczies, Jan, Allgäuer, Michael, Christopoulos, Petros, Stenzinger, Albrecht, Volckmar, Anna-Lena

“…•NGS revealed potentially targetable rare oncogenic fusions in 1–2% of NSCLC.•Among 43 detected rare fusions, 56% were novel and 26% non-functional.•No…”
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Computed tomography and magnetic resonance imaging in cystic fibrosis lung disease by Eichinger, Monika, Heussel, Claus-Peter, Kauczor, Hans-Ulrich, Tiddens, Harm, Puderbach, Michael

“…Computed tomography (CT) is the current “gold standard” for assessment of lung morphology and is so far the most reliable imaging modality for monitoring…”
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Protocol of the TREASURE study: Thoracic RadiothErapy with Atezolizumab in Small cell lUng canceR Extensive disease – a randomized, open-label, multicenter phase II trial by Bozorgmehr, Farastuk, Christopoulos, Petros, Chung, Inn, Cvetkovic, Jelena, Feisst, Manuel, Krisam, Johannes, Schneider, Marc A, Heussel, Claus Peter, Kreuter, Michael, Müller, Daniel W, Thomas, Michael, Rieken, Stefan

“…Abstract Background Recently, the combination of the programmed death-ligand 1 (PD-L1) inhibitor atezolizumab with first-line chemotherapy has demonstrated to…”
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Re-irradiation in locally recurrent lung cancer patients by Schlampp, Ingmar, Rieber, Juliane, Adeberg, Sebastian, Bozorgmehr, Farastuk, Heußel, Claus Peter, Steins, Martin, Kappes, Jutta, Hoffmann, Hans, Welzel, Thomas, Debus, Jürgen, Rieken, Stefan

“…Purpose Lung cancer remains one of the tumour diagnoses with high lethality, although innovative treatment approaches have yielded improvements in local…”
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Detection of TP53 Mutations in Tissue or Liquid Rebiopsies at Progression Identifies ALK+ Lung Cancer Patients with Poor Survival by Christopoulos, Petros, Dietz, Steffen, Kirchner, Martina, Volckmar, Anna-Lena, Endris, Volker, Neumann, Olaf, Ogrodnik, Simon, Heussel, Claus-Peter, Herth, Felix J, Eichhorn, Martin, Meister, Michael, Budczies, Jan, Allgäuer, Michael, Leichsenring, Jonas, Zemojtel, Tomasz, Bischoff, Helge, Schirmacher, Peter, Thomas, Michael, Sültmann, Holger, Stenzinger, Albrecht

“…Anaplastic lymphoma kinase (ALK) sequencing can identify resistance mechanisms and guide next-line therapy in ALK+ non-small-cell lung cancer (NSCLC), but the…”
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Evaluation of Prediction Models for Identifying Malignancy in Pulmonary Nodules Detected via Low-Dose Computed Tomography by González Maldonado, Sandra, Delorme, Stefan, Hüsing, Anika, Motsch, Erna, Kauczor, Hans-Ulrich, Heussel, Claus-Peter, Kaaks, Rudolf

“…Malignancy prediction models based on participant-related characteristics and imaging parameters from low-dose computed tomography (CT) may improve…”
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