Search Results - "HESSLER, G"

Impact of the Higgs boson on the production of exotic particles at the LHC by Hessler, A. G., Ibarra, A., Molinaro, E., Vogl, S.

“…Many new physics models contain new particles that interact with the Higgs boson. These particles could be produced at the LHC via gluon-gluon fusion with an…”
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Discovery and pharmacological characterization of a novel potent inhibitor of diacylglycerol‐sensitive TRPC cation channels by Maier, T, Follmann, M, Hessler, G, Kleemann, H‐W, Hachtel, S, Fuchs, B, Weissmann, N, Linz, W, Schmidt, T, Löhn, M, Schroeter, K, Wang, L, Rütten, H, Strübing, C

“…Background and Purpose The cation channel transient receptor potential canonical (TRPC) 6 has been associated with several pathologies including focal…”
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Drug Design Strategies for Targeting G-Protein-Coupled Receptors by Klabunde, Thomas, Hessler, Gerhard

“…G‐protein‐coupled receptors (GPCRs) form a large protein family that plays an important role in many physiological and pathophysiological processes. Since the…”
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Clinical Utility Validation of an Automated Ultrarapid Gene Fusion Assay for NSCLC by Buglioni, Alessia, Caffes, Patricia L., Hessler, Mark G., Mansfield, Aaron S., Lo, Ying-Chun

“…Gene rearrangements are frequent oncologic drivers in NSCLC, and many are suitable for treatment with Food and Drug Administration–approved or experimental…”
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Power Plant Construction Management - A Survival Guide (2nd Edition) by Hessler, Peter G

“…This timely 2nd Edition is revised and updated to include new technologies, evolving regulations, and the changing power generation mix between gas and coal…”
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Probing the scotogenic FIMP at the LHC by Hessler, Andre G., Ibarra, Alejandro, Molinaro, Emiliano, Vogl, Stefan

“…A bstract We analyse the signatures at the Large Hadron Collider (LHC) of the scotogenic model, when the lightest Z 2 -odd particle is a singlet fermion and a…”
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Association of a Lipoxygenase Locus, Lpx‐B1, with Variation in Lipoxygenase Activity in Durum Wheat Seeds by Hessler, T. G., Thomson, M. J., Benscher, D., Nachit, M. M., Sorrells, M. E.

“…Lipoxygenases constitute a family of enzymes that catalyze the breakdown of lipids, resulting in products that may have undesirable effects. These enzymes can…”
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Choosing the Right Solution Approach: The Crucial Role of Situational Knowledge in Electricity and Magnetism by Savelsbergh, Elwin R, de Jong, Ton, Ferguson-Hessler, Monica G. M

“…Novice problem solvers are rather sensitive to surface problem features, and they often resort to trial and error formula matching rather than identifying an…”
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RNA sequencing identifies a novel USP9X‐USP6 promoter swap gene fusion in a primary aneurysmal bone cyst by Blackburn, Patrick R., Davila, Jaime I., Jackson, Rory A., Fadra, Numrah, Atiq, Mazen A., Pitel, Beth A., Nair, Asha A., VanDeWalker, Todd J., Hessler, Mark G., Hovel, Sara K., Wehrs, Rebecca N., Fritchie, Karen J., Jenkins, Robert B., Halling, Kevin C., Geiersbach, Katherine B.

“…Primary aneurysmal bone cyst (ABC) is a benign multiloculated cystic lesion of bone that is defined cytogenetically by USP6 gene rearrangements. Rearrangements…”
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Discovery and evaluation of piperidinyl carboxylic acid derivatives as potent α4β1 integrin antagonists by MÜLLER, G, ALBERS, M, FISCHER, R, HESSLER, G, LEHMANN, T. E, OKIGAMI, H, TAJIMI, M, BACON, K, RÖLLE, T

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Conformation of cyclic peptides. Principle concepts and the design of selectivity and superactivity in bioactive sequences by 'spatial screening' by Kessler, H., Gratias, R., Hessler, G., Gurrath, M., Müller, G.

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Universality of strength of Yukawa couplings, quark singlets and strength of CP violation by Branco, G. C., Ferreira, H. R. Colaço, Hessler, A. G., Silva-Marcos, J. I.

“…A bstract We analyse the strength of CP violation in an extension of the standard model with an extra Q  = −1/3 vector-like singlet quark, in the framework of…”
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Virtual Screening of Biogenic Amine-Binding G-Protein Coupled Receptors:  Comparative Evaluation of Protein- and Ligand-Based Virtual Screening Protocols by Evers, Andreas, Hessler, Gerhard, Matter, Hans, Klabunde, Thomas

“…In this paper, we compare protein- and ligand-based virtual screening techniques for identifying the ligands of four biogenic amine-binding G-protein coupled…”
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Enhancing compound safety assessment using “Multitask” deep neural nets by Wenzel, J., Anger, L., Amberg, A., Matter, H., Hessler, G., Griesang, N., Mertsch, K., Czich, A., Schmidt, F.

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Cognitive Structures of Good and Poor Novice Problem Solvers in Physics by de Jong, Ton, Ferguson-Hessler, Monica G. M

“…The way knowledge is organized in memory is generally expected to relate to the degree of success in problem solving. In the present study, we investigated…”
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Structure of a stereoregular phosphorothioate DNA/RNA duplex by Bachelin, M, Hessler, G, Kurz, G, Hacia, J. G, Dervan, P. B, Kessler, H

“…In this work, we present the first NMR solution structure of a DNA/RNA hybrid containing stereoregular Rp-phosphorothioate modifications of all DNA backbone…”
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Learning physics with a computer algebra system by Savelsbergh, Elwin Rudolf, Jong, Ton de, Ferguson-Hessler, Monica G. M

“…To become proficient problem‐solvers, physics students need to form a coherent and flexible understanding of problem situations with which they are confronted…”
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CACHE (Critical Assessment of Computational Hit-finding Experiments): A public–private partnership benchmarking initiative to enable the development of computational methods for hit-finding by Ackloo, Suzanne, Al-awar, Rima, Amaro, Rommie E., Arrowsmith, Cheryl H., Azevedo, Hatylas, Batey, Robert A., Bengio, Yoshua, Betz, Ulrich A. K., Bologa, Cristian G., Chodera, John D., Cornell, Wendy D., Dunham, Ian, Ecker, Gerhard F., Edfeldt, Kristina, Edwards, Aled M., Gilson, Michael K., Gordijo, Claudia R., Hessler, Gerhard, Hillisch, Alexander, Hogner, Anders, Irwin, John J., Jansen, Johanna M., Kuhn, Daniel, Leach, Andrew R., Lee, Alpha A., Lessel, Uta, Morgan, Maxwell R., Moult, John, Muegge, Ingo, Oprea, Tudor I., Perry, Benjamin G., Riley, Patrick, Rousseaux, Sophie A. L., Saikatendu, Kumar Singh, Santhakumar, Vijayaratnam, Schapira, Matthieu, Scholten, Cora, Todd, Matthew H., Vedadi, Masoud, Volkamer, Andrea, Willson, Timothy M.

“…One aspirational goal of computational chemistry is to predict potent and drug-like binders for any protein, such that only those that bind are synthesized. In…”
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Experiments with statistical objective analysis techniques for representing a coastal surface temperature field by HESSLER, G

“…For interpretation of thermally driven mesoscale circulation systems, meteorologists are interested in detailed structures of boundary layer temperature…”
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Stimulation of erythrocyte ceramide formation by platelet-activating factor by Lang, Philipp A, Kempe, Daniela S, Tanneur, Valerie, Eisele, Kerstin, Klarl, Barbara A, Myssina, Svetlana, Jendrossek, Verena, Ishii, Satoshi, Shimizu, Takao, Waidmann, Marc, Hessler, Gabriele, Huber, Stephan M, Lang, Florian, Wieder, Thomas

“…Osmotic erythrocyte shrinkage leads to activation of cation channels with subsequent Ca²⁺ entry and stimulates a sphingomyelinase with subsequent formation of…”
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