Search Results - "HERTZ, CHRISTIN L."
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Levels of circulating semaglutide determine reductions in HbA1c and body weight in people with type 2 diabetes
Published in Cell reports. Medicine (21-09-2021)“…Glucagon-like peptide-1 receptor agonists (GLP-1RA) are used for the treatment of type 2 diabetes. Whether clinically important responses and adverse events…”
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Long-term efficacy and safety of oral semaglutide and the effect of switching from sitagliptin to oral semaglutide in patients with type 2 diabetes: a 52-week, randomized, open-label extension of the PIONEER 7 trial
Published in BMJ open diabetes research & care (01-12-2020)“…IntroductionThe PIONEER 7 trial demonstrated superior glycemic control and weight loss with once-daily oral semaglutide with flexible dose adjustment versus…”
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3
Personality in Adults Who Were Born Very Preterm
Published in PloS one (26-06-2013)“…To investigate the personality in very preterm individuals (VPT; gestational age, GA, <32 weeks) at adult age in two cohorts born in 1974-76 and 1980-82,…”
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PIONEER 1: Randomized Clinical Trial of the Efficacy and Safety of Oral Semaglutide Monotherapy in Comparison With Placebo in Patients With Type 2 Diabetes
Published in Diabetes care (01-09-2019)“…This trial compared the efficacy and safety of the first oral glucagon-like peptide 1 (GLP-1) receptor agonist, oral semaglutide, as monotherapy with placebo…”
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5
670-P: Time Spent in Glycemic Control after Initiating Treatment with Oral Semaglutide vs. Empagliflozin: An Exploratory Analysis of the PIONEER 2 Trial
Published in Diabetes (New York, N.Y.) (01-06-2021)“…A standard objective in the management of T2D is the achievement and maintenance of HbA1c targets, but the duration of time that patients spend within glycemic…”
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6
Cardiovascular risk factors early in the course of treatment in people with type 2 diabetes without established cardiovascular disease: A population‐based observational retrospective cohort study
Published in Diabetic medicine (01-03-2022)“…Aims To characterise the cardiovascular risk of people with type 2 diabetes without established cardiovascular disease but with risk factors, relative to those…”
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932-P: Efficacy and Safety of Oral Semaglutide by Baseline Age in the PIONEER Clinical Trial Program
Published in Diabetes (New York, N.Y.) (01-06-2020)“…In an exploratory analysis of 7 global phase 3a trials (PIONEER 1-5, 7, and 8) we evaluated the effect of age at baseline on efficacy (<45, ≥45-<65, or ≥65…”
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964-P: Glycemic and Body Weight Responses to Oral Semaglutide in the PIONEER Trial Program
Published in Diabetes (New York, N.Y.) (01-06-2020)“…The PIONEER phase 3 program investigated glycemic response and other efficacy endpoints in patients (pts) with type 2 diabetes randomized to the glucagon-like…”
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957-P: Efficacy of Oral Semaglutide According to Background Medication: An Exploratory Subgroup Analysis of the PIONEER Trial Program
Published in Diabetes (New York, N.Y.) (01-06-2020)“…The global PIONEER program investigated the efficacy and safety of the first oral glucagon-like peptide-1 receptor agonist, oral semaglutide. Across PIONEER…”
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10
A comparison of genetic findings in sudden cardiac death victims and cardiac patients: the importance of phenotypic classification
Published in Europace (London, England) (01-03-2015)“…Sudden cardiac death (SCD) is responsible for a large proportion of non-traumatic, sudden and unexpected deaths in young individuals. Sudden cardiac death is a…”
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Oral Semaglutide Reduces HbA1c and Body Weight in Patients with Type 2 Diabetes Regardless of Background Glucose-Lowering Medication: PIONEER Subgroup Analyses
Published in Diabetes therapy (01-04-2021)“…Introduction The efficacy and safety of oral semaglutide, the first oral glucagon-like peptide-1 receptor agonist, were investigated in patients with type 2…”
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12
Efficacy and safety of oral semaglutide with flexible dose adjustment versus sitagliptin in type 2 diabetes (PIONEER 7): a multicentre, open-label, randomised, phase 3a trial
Published in The lancet. Diabetes & endocrinology (01-07-2019)“…Oral semaglutide is the first oral formulation of a glucagon-like peptide-1 (GLP-1) receptor agonist developed for the treatment of type 2 diabetes. We aimed…”
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13
Effect and Safety of Oral Semaglutide Monotherapy in Type 2 Diabetes—PIONEER 1 Trial
Published in Diabetes (New York, N.Y.) (01-07-2018)“…Oral semaglutide (sema), the first GLP-1 receptor agonist in a tablet formulation, is in late-stage development for the treatment of T2D. The effect and safety…”
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14
983-P: Effect and Safety of Flexible Dose Adjustment with Oral Semaglutide vs. Sitagliptin in Type 2 Diabetes: PIONEER 7
Published in Diabetes (New York, N.Y.) (01-06-2019)“…Oral semaglutide (sema) is the first oral GLP-1 receptor agonist (RA). Flexible dose adjustment of oral sema (3, 7, and 14 mg) once daily (N=253) was tested…”
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15
Abstract 34: Time spent in glycemic control after initiating treatment with oral semaglutide versus empagliflozin: An exploratory analysis of the PIONEER 2 trial
Published in Indian journal of endocrinology and metabolism (01-03-2022)“…A standard objective in the management of T2D is the achievement and maintenance of HbA1C targets, but the duration of time that patients spend within glycemic…”
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16
Oral Semaglutide Reduces HbA.sub.1c and Body Weight in Patients with Type 2 Diabetes Regardless of Background Glucose-Lowering Medication: PIONEER Subgroup Analyses
Published in Diabetes therapy (01-04-2021)“…Introduction The efficacy and safety of oral semaglutide, the first oral glucagon-like peptide-1 receptor agonist, were investigated in patients with type 2…”
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Journal Article -
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Abstract 15: Glycemic and body weight responses to oral semaglutide in the PIONEER trial program
Published in Indian journal of endocrinology and metabolism (01-03-2022)“…Case: The PIONEER phase 3 program investigated glycemic response and other efficacy endpoints in patients (pts) with type 2 diabetes randomized to the…”
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18
Oral Semaglutide Reduces HbA 1c and Body Weight in Patients with Type 2 Diabetes Regardless of Background Glucose-Lowering Medication: PIONEER Subgroup Analyses
Published in Diabetes therapy (01-04-2021)“…The efficacy and safety of oral semaglutide, the first oral glucagon-like peptide-1 receptor agonist, were investigated in patients with type 2 diabetes (T2D)…”
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Journal Article