Search Results - "HERSCHER, Laurie L"

Phase I study of weekly gemcitabine as a radiation sensitizer for unresectable pancreatic cancer by Poggi, Matthew M, Kroog, Glenn S, Russo, Angelo, Muir, Christine, Cook, John, Smith, Judith, Mitchell, James B, Herscher, Laurie L

“…To determine the maximal tolerated dose and dose-limiting toxicities (DLTs) of weekly gemcitabine with concurrent radiotherapy (RT) in patients with…”
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Concurrent Paclitaxel and Radiation in the Treatment of Locally Advanced Head and Neck Cancer by SUNWOO, John B, HERSCHER, Laurie L, RUDY, Susan, MUIR, Chris, SUOPING ZHAI, FIGG, William D, COOK, John A, MITCHELL, James B, VAN WAES, Carter, KROOG, Glenn S, THOMAS, Giovana R, ONDREY, Frank G, DUFFEY, Dianne C, SOLOMON, Beth I, BOSS, Carol, ALBERT, Paul S, MCCULLUGH, Linda

“…To determine the feasibility of an organ preservation regimen consisting of infusional paclitaxel administered concurrently with radiotherapy to patients with…”
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Expression of Proinflammatory and Proangiogenic Cytokines in Patients with Head and Neck Cancer by ZHONG CHEN, MALHOTRA, P. S, MCCULLAGH, L, MOUSA, S, QUEZADO, M, HERSCHER, L. L, VAN WAES, C, THOMAS, G. R, ONDREY, F. G, DUFFEY, D. C, SMITH, C. W, ENAMORADO, I, YEH, N. T, KROOG, G. S, RUDY, S

“…Altered immune, inflammatory, and angiogenesis responses are observed in patients with head and neck squamous cell carcinoma (HNSCC), and many of these…”
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Safety and efficacy of adenovirus-mediated transfer of the human aquaporin-1 cDNA to irradiated parotid glands of non-human primates by O'Connell, A C, Baccaglini, L, Fox, P C, O'Connell, B C, Kenshalo, D, Oweisy, H, Hoque, A T, Sun, D, Herscher, L L, Braddon, V R, Delporte, C, Baum, B J

“…This study evaluated the safety and efficacy of a single administration of a recombinant adenovirus encoding human aquaporin-1 (AdhAQP1) to the parotid glands…”
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A pilot study of longitudinal serum cytokine and angiogenesis factor levels as markers of therapeutic response and survival in patients with head and neck squamous cell carcinoma by Druzgal, Colleen H., Chen, Zhong, Yeh, Ning T., Thomas, Giovana R., Ondrey, Frank G., Duffey, Dianne C., Vilela, Ronald J., Ende, Kevin, McCullagh, Linda, Rudy, Susan F., Muir, Christine, Herscher, Laurie L., Morris, John C., Albert, Paul S., Van Waes, Carter

“…Background. Head and neck squamous cell carcinomas (HNSCCs) were previously shown to express a repertoire of cytokines and angiogenesis factors that contribute…”
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Intraperitoneal gemcitabine pharmacokinetics: a pilot and pharmacokinetic study in patients with advanced adenocarcinoma of the pancreas by Gamblin, T. Clark, Egorin, Merrill J., Zuhowski, Eleanor G., Lagattuta, Theodore F., Herscher, Laurie L., Russo, Angelo, Libutti, Steven K., Alexander, H. Richard, Dedrick, Robert L., Bartlett, David L.

“…Background The pyrimidine analogue gemcitabine (2′, 2′-difluorodeoxycitidine, dFdC) is active against pancreatic cancer, and its high clearance (CL tb ) and…”
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Taxanes as radiosensitizers for head and neck cancer by Herscher, Laurie L, Cook, John

“…Combinations of paclitaxel and radiation therapy or paclitaxel with other chemotherapy agents and radiation have been tested with variable results in patient…”
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Principles of chemoradiation: theoretical and practical considerations by Herscher, L L, Cook, J A, Pacelli, R, Pass, H I, Russo, A, Mitchell, J B

“…Chemotherapy agents known to enhance the effects of radiation in preclinical studies have been used concurrently with radiotherapy in numerous clinical trials…”
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Phase I study of paclitaxel as a radiation sensitizer in the treatment of mesothelioma and non-small-cell lung cancer by Herscher, L L, Hahn, S M, Kroog, G, Pass, H, Temeck, B, Goldspiel, B, Cook, J, Mitchell, J B, Liebmann, J

“…To determine the maximum-tolerated dose (MTD) and dose-limiting toxicities of paclitaxel with concurrent thoracic irradiation in patients with malignant…”
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National Cancer Institute (phase II) study of high-grade glioma treated with accelerated hyperfractionated radiation and iododeoxyuridine: results in anaplastic astrocytoma by Sullivan, F J, Herscher, L L, Cook, J A, Smith, J, Steinberg, S M, Epstein, A H, Oldfield, E H, Goffman, T E, Kinsella, T J, Mitchell, J B

“…We report the outcome of a Phase II study of a cohort of patients with high-grade glioma treated with accelerated hyperfractionated radiation and the radiation…”
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Protection against SR 4233 (Tirapazamine) aerobic cytotoxicity by the metal chelators desferrioxamine and tiron by Herscher, L L, Krishna, M C, Cook, J A, Coleman, C N, Biaglow, J E, Tuttle, S W, Gonzalez, F J, Mitchell, J B

“…Metal chelating agents and antioxidants were evaluated as potential protectors against aerobic SR 4233 cytotoxicity in Chinese hamster V79 cells. The…”
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Myocytolysis (vacuolar degeneration) of myocardium: immunohistochemical evidence of viability by Edwalds, G M, Said, J W, Block, M I, Herscher, L L, Siegel, R J, Fishbein, M C

“…Human myocardium with focal myocytolysis (vacuolar degeneration, colliquative myocytolysis) was examined by routine light microscopy and by immunoperoxidase…”
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Distribution of LDH-1 in normal, ischemic, and necrotic myocardium. An immunoperoxidase study by Herscher, L L, Siegel, R J, Said, J W, Edwalds, G M, Moran, M M, Fishbein, M C

“…To study the distribution of lactate dehydrogenase (LDH-1) (H4) in normal, ischemic, and necrotic myocardium using the peroxidase-antiperoxidase technic, the…”
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