Search Results - "HERRLICH, P"
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Cross-talk between glucocorticoid receptor and AP-1: AP-1
Published in Oncogene (30-04-2001)“…Cross-talk between different transcription factors, notably between the glucocorticoid receptor and AP-1, has been discovered more than 10 years ago: a bona…”
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2
ATF‐2 is preferentially activated by stress‐activated protein kinases to mediate c‐jun induction in response to genotoxic agents
Published in The EMBO journal (18-04-1995)“…The major regulators of the c‐jun promoter are ATF‐2 and c‐Jun. They act as pre‐bound heterodimers on two ‘AP‐1‐like’ sites, and are preferentially addressed…”
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3
Dephosphorylation of receptor tyrosine kinases as target of regulation by radiation, oxidants or alkylating agents
Published in The EMBO journal (01-10-1996)“…Several non‐physiologic agents such as radiation, oxidants and alkylating agents induce ligand‐independent activation of numerous receptor tyrosine kinases…”
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4
A distinct modulating domain in glucocorticoid receptor monomers in the repression of activity of the transcription factor AP‐1
Published in The EMBO journal (01-09-1994)“…Steroid receptors activate and repress genes. An important class of genes that they repress is controlled by the transcription factor AP‐1. The activity of…”
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5
A splice variant of CD44 expressed in the apical ectodermal ridge presents fibroblast growth factors to limb mesenchyme and is required for limb outgrowth
Published in Genes & development (01-04-1998)“…Signals from the apical ectodermal ridge (AER) of the developing vertebrate limb, including fibroblast growth factor-8 (FGF-8), can maintain limb mesenchymal…”
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6
Prevention of tumor metastasis formation by anti-variant CD44
Published in The Journal of experimental medicine (01-02-1993)“…A splice variant of CD44 (CD44v) originally discovered on metastases of a rat pancreatic adenocarcinoma (BSp73ASML) has been shown by transfection to confer…”
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7
CD44 variant exon epitopes in primary breast cancer and length of survival
Published in The Lancet (British edition) (11-03-1995)“…CD44 designates a group of closely related cell-surface proteins generated by alternative splicing. We have previously shown that splice variants carrying…”
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8
CREB is activated by UVC through a p38/HOG-1-dependent protein kinase
Published in The EMBO journal (01-03-1997)“…Changes in environmental conditions such as the addition of growth factors or irradiation of cells in culture first affect immediate response genes. We have…”
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Activated human lymphocytes and aggressive non-Hodgkin's lymphomas express a homologue of the rat metastasis-associated variant of CD44
Published in The Journal of experimental medicine (01-04-1993)“…A recently described splice variant of CD44 expressed in metastasizing cell lines of rat tumors, has been shown to confer metastatic potential to…”
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10
Heterodimer formation of cJun and ATF‐2 is responsible for induction of c‐jun by the 243 amino acid adenovirus E1A protein
Published in The EMBO journal (01-02-1993)“…The adenovirus E1A proteins differentially regulate AP‐1‐responsive genes. Collagenase and stromelysin are repressed by E1A, whereas the expression of c‐jun is…”
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11
Cd44 in colon cancer
Published in European journal of cancer (1990) (01-07-1995)“…Alternative splicing of ten different variant exons (v1–vl0) is responsible for the creation of a large number of different CD44 surface proteins. Some of…”
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12
UV-induced signal transduction
Published in Journal of Photochemistry & Photobiology, B: Biology (1997)“…Irradiation of cell with short wavelength ultraviolet light (UVA, B and C) induces the transcription of many genes. The program overiaps with that induced by…”
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13
UV-induced DNA damage is an intermediate step in UV-induced expression of human immunodeficiency virus type 1, collagenase, c-fos, and metallothionein
Published in Molecular and Cellular Biology (01-11-1989)“…Article Usage Stats Services MCB Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley…”
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14
A Human Homologue of the Rat Metastasis-Associated Variant of CD44 Is Expressed in Colorectal Carcinomas and Adenomatous Polyps
Published in The Journal of cell biology (01-01-1993)“…A recently described splice variant of CD44 expressed in metastasizing cell lines of rat tumors has been shown to confer metastatic potential to a…”
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15
Interference between pathway‐specific transcription factors: glucocorticoids antagonize phorbol ester‐induced AP‐1 activity without altering AP‐1 site occupation in vivo
Published in The EMBO journal (01-06-1992)“…Phorbol esters stimulate and glucocorticoid hormones down‐regulate a variety of promoters such as that of the collagenase gene through the transcription factor…”
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16
UV‐induced activation of AP‐1 involves obligatory extranuclear steps including Raf‐1 kinase
Published in The EMBO journal (01-03-1993)“…Irradiation of cells with ultraviolet light (UV) leads to modifications of c‐Jun resembling those elicited by phorbol esters or oncogenes, and to enhanced…”
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12-O-tetradecanoyl-phorbol-13-acetate induction of the human collagenase gene is mediated by an inducible enhancer element located in the 5'-flanking region
Published in Molecular and Cellular Biology (01-06-1987)“…Article Usage Stats Services MCB Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley…”
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18
UV irradiation-induced interleukin-1 and basic fibroblast growth factor synthesis and release mediate part of the UV response
Published in The Journal of biological chemistry (25-03-1993)“…UV irradiated cells release into the culture medium factors that induce, when given to nonirradiated cells, the transcription of several UV-inducible genes…”
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19
Autocrine growth and anchorage independence: two complementing Jun-controlled genetic programs of cellular transformation
Published in Genes & development (15-04-1998)“…Cellular transformation can be achieved by constitutive activation of growth-regulatory signaling pathways, which, in turn, activate nuclear transcription…”
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Two different functions for CD44 proteins in human myelopoiesis
Published in The Journal of clinical investigation (01-09-1998)“…CD44 is important during myelopoiesis, although the contributions of variant CD44 proteins are unclear. We show here that in human long-term bone marrow…”
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