Search Results - "HERMSEN, Mario A. J. A"

Genomic stability and functional activity may be lost in telomerase-transduced human CD8+ T lymphocytes by Schreurs, Marco W.J., Hermsen, Mario A.J.A., Geltink, Ramon I. Klein, Scholten, Kirsten B.J., Brink, Antoinette A.T.P., Kueter, Esther W.M., Tijssen, Marianne, Meijer, Chris J.L.M., Ylstra, Bauke, Meijer, Gerrit A., Hooijberg, Erik

“…To obtain the large amount of T cells required for adoptive immunotherapy in a clinical setting, T-cell lifespan extension by human telomerase reverse…”
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Promoter methylation precedes chromosomal alterations in colorectal cancer development by Derks, Sarah, Postma, Cindy, Moerkerk, Peter T M, van den Bosch, Sandra M, Carvalho, Beatriz, Hermsen, Mario A J A, Giaretti, Walter, Herman, James G, Weijenberg, Matty P, de Bruïne, Adriaan P, Meijer, Gerrit A, van Engeland, Manon

“…Colorectal cancers are characterized by genetic and epigenetic alterations. This study aimed to explore the timing of promoter methylation and relationship…”
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Comparative Genomic Hybridization of Microdissected Familial Ovarian Carcinoma: Two Deleted Regions on Chromosome 15q Not Previously Identified in Sporadic Ovarian Carcinoma by Zweemer, Ronald P, Ryan, Andy, Snijders, Antoine M, Hermsen, Mario A J A, Meijer, Gerrit A, Beller, Uziel, Menko, Fred H, Jacobs, Ian J, Baak, Jan P A, Verheijen, René H M, Kenemans, Peter, van Diest, Paul J

“…The vast majority of familial ovarian cancers harbor a germline mutation in either the breast cancer gene BRCA1 or BRCA2 tumor suppressor genes. However,…”
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Generation and molecular characterization of head and neck squamous cell lines of Fanconi anemia patients by VAN ZEEBURG, Hester J. T, SNIJDERS, Peter J. F, JOENJE, Hans, BRAKENHOFF, Ruud H, PALS, Gerard, HERMSEN, Mario A. J. A, ROOIMANS, Martin A, BAGBY, Grover, SOULIER, Jean, GLUCKMAN, Eliane, WENNERBERG, Johan, LEEMANS, C. René

“…Patients with Fanconi anemia (FA) are prone to develop malignancies at an early age. Besides hematologic malignancies, squamous cell carcinomas in the…”
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In lymph node-negative invasive breast carcinomas, specific chromosomal aberrations are strongly associated with high mitotic activity and predict outcome more accurately than grade, tumour diameter, and oestrogen receptor by Janssen, Emiel AM, Baak, Jan PA, Guervós, Marta Alonso, van Diest, Paul J, Jiwa, M, Hermsen, Mario AJA

“…The objectives of this study were to analyse whether specific chromosomal gains and losses in lymph‐node negative breast cancer correlate with other features…”
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Protein expression of B-cell lymphoma gene 6 (BCL-6) in invasive breast cancer is associated with cyclin D1 and hypoxia-inducible factor-1α (HIF-1α) by Bos, Reinhard, Diest, Paul J van, Groep, Petra van der, Greijer, Astrid E, Hermsen, Mario A J A, Heijnen, Ingrid, Meijer, Gerrit A, Baak, Jan P A, Pinedo, Herbert M, Wall, Elsken van der, Shvarts, Avi

“…B-cell lymphoma gene (BCL-6) upregulation contributes to immortalization of mouse embryo fibroblast and primary B cells via upregulation of cyclin D1. As…”
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Genetic alterations in childhood medulloblastoma analyzed by comparative genomic hybridization by MICHIELS, Erna M. C, WEISS, Marjan M, HOOVERS, Jan M. N, BAAK, Jan P. A, VOUTE, P. A, BAAS, Frank, HERMSEN, Mario A. J. A

“…Despite intensive therapy, the survival of children with medulloblastoma remains disappointing. Moreover, children who survive are affected by serious…”
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Barrett's adenocarcinomas resemble adenocarcinomas of the gastric cardia in terms of chromosomal copy number changes, but relate to squamous cell carcinomas of the distal oesophagus with respect to the presence of high-level amplifications by Weiss, Marjan M, Kuipers, Ernst J, Hermsen, Mario AJA, van Grieken, Nicole CT, Offerhaus, Johan, Baak, Jan PA, Meuwissen, Stefan GM, Meijer, Gerrit A

“…Three different cancers predominantly occur at the gastro‐oesophageal junction: squamous cell carcinomas of the distal oesophagus, adenocarcinomas of the…”
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Helicobacter pylori-related and -non-related gastric cancers do not differ with respect to chromosomal aberrations by van Grieken, Nicole C. T., Weiss, Marjan M., Meijer, Gerrit A., Hermsen, Mario A. J. A., Scholte, Ger H. A., Lindeman, Jan, Craanen, Mikael E., Bloemena, Elisabeth, Meuwissen, Stefan G. M., Baak, Jan P. A., Kuipers, Ernst J.

“…Gastric carcinogenesis is strongly associated with Helicobacter pylori infection, but the underlying genetic mechanisms are largely unknown. The aim of this…”
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Simultaneous chromosome 1q gain and 16q loss is associated with steroid receptor presence and low proliferation in breast carcinoma by Farabegoli, Fulvia, Hermsen, Mario A J A, Ceccarelli, Claudio, Santini, Donatella, Weiss, Marianne M, Meijer, Gerrit A, Diest, Paul J van

“…We applied comparative genomic hybridization (CGH) to 46 breast carcinoma samples, collected from 1993 to 1995, in order to detect chromosome 1q gains and 16q…”
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Distinct chromosomal aberrations in Epstein-Barr virus–carrying gastric carcinomas tested by comparative genomic hybridization by Hausen, Axel Zur, Van Grieken, Nicole C.T., Meijer, Gerrit A., Hermsen, Mario A.J.A., Bloemena, Elisabeth, Meuwissen, Stefan G.M., Baak, Jan P.A., Meijer, Chris J.L.M., Kuipers, Ernst J., Van Den Brule, Adriaan J.C.

“…Background & Aims: Approximately 10% of gastric adenocarcinomas carry the human pathogenic Epstein-Barr virus (EBV). The role of EBV in the pathogenesis of…”
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Genetic analysis of 53 lymph node-negative breast carcinomas by CGH and relation to clinical, pathological, morphometric, and DNA cytometric prognostic factors by Hermsen, Mario A. J. A., Baak, Jan P. A., Meijer, Gerrit A., Weiss, Janneke M., Walboomers, Jan W. W., Snijders, Peter J. F., Van Diest, Paul J.

“…Within the subgroup of lymph node‐negative breast cancers, there is a need for accurate prognostic indicators to select high‐risk patients. Comparative genomic…”
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Integrated human papillomavirus type 16 and loss of heterozygosity at 11q22 and 18q21 in an oral carcinoma and its derivative cell line by STEENBERGEN, R. D. M, HERMSEN, M. A. J. A, WALBOOMERS, J. M. M, JOENJE, H, ARWERT, F, MEIJERT, C. J. L. M, SNIJDERS, P. J. F

“…A human papillomavirus (HPV) type 16 containing oral squamous cell carcinoma cell line 93VU147T at early passage was demonstrated to match its primary tumor…”
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High resolution microarray CGH and MLPA analysis for improved genotype/phenotype evaluation of two childhood genetic disorder cases: ring chromosome 19 and partial duplication 2q by Hermsen, Mario A.J.A., Tijssen, Marianne, Acero, Ines Hernando, Meijer, Gerrit A., Ylstra, Bauke, Toral, Joaquín Fernández

“…A detailed analysis of the constitutional chromosomal changes in two pediatric patients was performed using high resolution genetic analysis techniques,…”
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Centromeric breakage as a major cause of cytogenetic abnormalities in oral squamous cell carcinoma by Hermsen, Mario A. J. A., Joenje, Hans, Arwert, Fré, Welters, Marij J. P., Braakhuis, Boudewijn J. M., Bagnay, Marjan, Westerveld, Andries, Slater, Rosalyn

“…Cytogenetic analysis of short‐term explant tumor cultures derived from 11 human oral squamous cell carcinomas (nine from primary tumors and two from nude mice…”
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Protein expression of B-cell lymphoma gene 6 by Bos, Reinhard, Diest, Paul J van, Groep, Petra van der, Greijer, Astrid E, Hermsen, Mario A J A, Heijnen, Ingrid, Meijer, Gerrit A, Baak, Jan P A, Pinedo, Herbert M, Wall, Elsken van der, Shvarts, Avi

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Protein expression of B-cell lymphoma gene 6 (BCL-6) in invasive breast cancer is associated with cyclin D1 and hypoxia-inducible factor-1alpha (HIF-1alpha) by Bos, Reinhard, van Diest, Paul J, van der Groep, Petra, Greijer, Astrid E, Hermsen, Mario A J A, Heijnen, Ingrid, Meijer, Gerrit A, Baak, Jan P A, Pinedo, Herbert M, van der Wall, Elsken, Shvarts, Avi

“…B-cell lymphoma gene (BCL-6) upregulation contributes to immortalization of mouse embryo fibroblast and primary B cells via upregulation of cyclin D1. As…”
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From chromosomes to molecular karyotyping : High resolution microarray CGH and MLPA analysis for improved genotype/phenotype evaluation of two childhood genetic disorder cases : ring chromosome19 and partial duplication 2q by HERMSEN, Mario A. J. A, TIJSSEN, Marianne, ACERO, Ines Hemando, MEIJER, Gerrit A, YLSTRA, Bauke, FERNANDEZ TORAL, Joaquin

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Comparative genomic hybridization in cancer investigations by Weiss, Marjan M, Hermsen, Mario A J A, Meijer, Gerrit A, van Diest, Paul J

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Non‐random allelic losses at 3p, 11p and 13q during HPV‐mediated immortalization and concomitant loss of terminal differentiation of human keratinocytes by Steenbergen, Renske D. M., Hermsen, Mario A. J. A., Walboomers, Jan M. M., Meijer, Gerrit A., Baak, Jan P. A., Meijer, Chris J. L. M., Snijders, Peter J. F.

“…To obtain a comprehensive overview of chromosomal alterations that may underlie human papillomavirus (HPV)‐mediated immortalization, 4 foreskin keratinocyte…”
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