Search Results - "HERMOSO, MARCELA A."

Impact of Bacterial Metabolites on Gut Barrier Function and Host Immunity: A Focus on Bacterial Metabolism and Its Relevance for Intestinal Inflammation by Gasaly, Naschla, de Vos, Paul, Hermoso, Marcela A.

“…The diverse and dynamic microbial community of the human gastrointestinal tract plays a vital role in health, with gut microbiota supporting the development…”
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Butyrate and the Fine-Tuning of Colonic Homeostasis: Implication for Inflammatory Bowel Diseases by Gasaly, Naschla, Hermoso, Marcela A, Gotteland, Martín

“…This review describes current evidence supporting butyrate impact in the homeostatic regulation of the digestive ecosystem in health and inflammatory bowel…”
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Short Chain Fatty Acids (SCFAs)-Mediated Gut Epithelial and Immune Regulation and Its Relevance for Inflammatory Bowel Diseases by Parada Venegas, Daniela, De la Fuente, Marjorie K, Landskron, Glauben, González, María Julieta, Quera, Rodrigo, Dijkstra, Gerard, Harmsen, Hermie J M, Faber, Klaas Nico, Hermoso, Marcela A

“…Ulcerative colitis (UC) and Crohn's disease (CD), collectively known as Inflammatory Bowel Diseases (IBD), are caused by a complex interplay between genetic,…”
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Chronic Inflammation and Cytokines in the Tumor Microenvironment by Thuwajit, Chanitra, Thuwajit, Peti, De la Fuente, Marjorie, Landskron, Glauben, Hermoso, Marcela A.

“…Acute inflammation is a response to an alteration induced by a pathogen or a physical or chemical insult, which functions to eliminate the source of the damage…”
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The IL-33/ST2 axis: Role in health and disease by De la Fuente, Marjorie, MacDonald, Thomas T, Hermoso, Marcela A

“…Highlights • Interleukin-33 (IL-33), is a member of the IL-1 cytokine family. • ST2L membrane-anchored receptor is activated by IL-33. • The soluble variant…”
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Immune System, Microbiota, and Microbial Metabolites: The Unresolved Triad in Colorectal Cancer Microenvironment by Hanus, Michelle, Parada-Venegas, Daniela, Landskron, Glauben, Wielandt, Ana Maria, Hurtado, Claudia, Alvarez, Karin, Hermoso, Marcela A, López-Köstner, Francisco, De la Fuente, Marjorie

“…Colorectal cancer (CRC) is one of the most common cancers worldwide. As with other cancers, CRC is a multifactorial disease due to the combined effect of…”
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Corrigendum: Short Chain Fatty Acids (SCFAs)-Mediated Gut Epithelial and Immune Regulation and Its Relevance for Inflammatory Bowel Diseases by Parada Venegas, Daniela, De la Fuente, Marjorie K, Landskron, Glauben, González, María Julieta, Quera, Rodrigo, Dijkstra, Gerard, Harmsen, Hermie J M, Faber, Klaas Nico, Hermoso, Marcela A

“…[This corrects the article DOI: 10.3389/fimmu.2019.00277.]…”
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Glucocorticoids mobilize macrophages by transcriptionally up-regulating the exopeptidase DPP4 by Diaz-Jimenez, David, Petrillo, Maria Grazia, Busada, Jonathan T., Hermoso, Marcela A., Cidlowski, John A.

“…Glucocorticoids are potent endogenous anti-inflammatory molecules, and their cognate receptor, glucocorticoid receptor (GR), is expressed in nearly all immune…”
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Aberrant MUC1 accumulation in salivary glands of Sjögren’s syndrome patients is reversed by TUDCA in vitro by Castro, Isabel, Albornoz, Nicolás, Aguilera, Sergio, Barrera, María-José, González, Sergio, Núñez, Matilde, Carvajal, Patricia, Jara, Daniela, Lagos, Carolina, Molina, Claudio, Urzúa, Ulises, Hermoso, Marcela A, González, María-Julieta

“…Abstract Objectives Xerostomia in SS patients has been associated with low quality and quantity of salivary mucins, which are fundamental for the hydration and…”
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The role of cholesterol and mitochondrial bioenergetics in activation of the inflammasome in IBD by Astorga, Jessica, Gasaly, Naschla, Dubois-Camacho, Karen, De la Fuente, Marjorie, Landskron, Glauben, Faber, Klaas Nico, Urra, Félix A, Hermoso, Marcela A

“…Inflammatory Bowel Disease (IBD) is characterized by a loss of intestinal barrier function caused by an aberrant interaction between the immune response and…”
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IL-33 Alarmin and Its Active Proinflammatory Fragments Are Released in Small Intestine in Celiac Disease by Perez, Federico, Ruera, Carolina N, Miculan, Emanuel, Carasi, Paula, Dubois-Camacho, Karen, Garbi, Laura, Guzman, Luciana, Hermoso, Marcela A, Chirdo, Fernando G

“…Initially described as Th2 promoter cytokine, more recently, IL-33 has been recognized as an alarmin, mainly in epithelial and endothelial cells. While…”
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Editorial: Intestinal Homeostasis and Disease: A Complex Partnership Between Immune Cells, Non-Immune Cells, and the Microbiome by De la Fuente, Marjorie, MacDonald, Thomas Thornton, Hermoso, Marcela A

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Inhibition of miR-378a-3p by Inflammation Enhances IL-33 Levels: A Novel Mechanism of Alarmin Modulation in Ulcerative Colitis by Dubois-Camacho, Karen, Diaz-Jimenez, David, De la Fuente, Marjorie, Quera, Rodrigo, Simian, Daniela, Martínez, Maripaz, Landskron, Glauben, Olivares-Morales, Mauricio, Cidlowski, John A, Xu, Xiaojiang, Gao, Guangping, Xie, Jun, Chnaiderman, Jonás, Soto-Rifo, Ricardo, González, María-Julieta, Calixto, Andrea, Hermoso, Marcela A

“…Ulcerative colitis (UC) is an inflammatory bowel disease (IBD) characterized by mucosa damage associated with an uncontrolled inflammatory response. This…”
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Corrigendum: The role of cholesterol and mitochondrial bioenergetics in activation of the inflammasome in IBD by Astorga, Jessica, Gasaly, Naschla, Dubois-Camacho, Karen, De la Fuente, Marjorie, Landskron, Glauben, Faber, Klaas Nico, Urra, Félix A, Hermoso, Marcela A

“…[This corrects the article DOI: 10.3389/fimmu.2022.1028953.]…”
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Endoplasmic reticulum stress in autoimmune diseases: Can altered protein quality control and/or unfolded protein response contribute to autoimmunity? A critical review on Sjögren's syndrome by Barrera, María-José, Aguilera, Sergio, Castro, Isabel, González, Sergio, Carvajal, Patricia, Molina, Claudio, Hermoso, Marcela A., González, María-Julieta

“…For many years, researchers in the field of autoimmunity have focused on the role of the immune components in the etiopathogenesis of autoimmune diseases…”
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Crosstalk between Tumor-Infiltrating Immune Cells and Cancer-Associated Fibroblasts in Tumor Growth and Immunosuppression of Breast Cancer by Soongsathitanon, Jarupa, Jamjuntra, Pranisa, Sumransub, Nuttavut, Yangngam, Supaporn, De la Fuente, Marjorie, Landskron, Glauben, Thuwajit, Peti, Hermoso, Marcela A., Thuwajit, Chanitra

“…Signals from the tumor microenvironment (TME) have a profound influence on the maintenance and progression of cancers. Chronic inflammation and the…”
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Characterization of Adherent-Invasive Escherichia coli (AIEC) Outer Membrane Proteins Provides Potential Molecular Markers to Screen Putative AIEC Strains by Saitz, Waleska, Montero, David A, Pardo, Mirka, Araya, Daniela, De la Fuente, Marjorie, Hermoso, Marcela A, Farfán, Mauricio J, Ginard, Daniel, Rosselló-Móra, Ramon, Rasko, Dave A, Del Canto, Felipe, Vidal, Roberto M

“…Adherent-invasive (AIEC) is a pathotype associated with the etiopathogenesis of Crohn's disease (CD), albeit with an as-yet unclear role. The main pathogenic…”
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Escherichia coli isolates from inflammatory bowel diseases patients survive in macrophages and activate NLRP3 inflammasome by De la Fuente, Marjorie, Franchi, Luigi, Araya, Daniela, Díaz-Jiménez, David, Olivares, Mauricio, Álvarez-Lobos, Manuel, Golenbock, Douglas, González, María-Julieta, López-Kostner, Francisco, Quera, Rodrigo, Núñez, Gabriel, Vidal, Roberto, Hermoso, Marcela A

“…Abstract Crohn's disease (CD) is a multifactorial pathology associated with the presence of adherent-invasive Escherichia coli (AIEC) and NLRP3 polymorphic…”
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Dysregulated Immune Responses in COVID-19 Patients Correlating With Disease Severity and Invasive Oxygen Requirements by García-González, Paulina, Tempio, Fabián, Fuentes, Camila, Merino, Consuelo, Vargas, Leonardo, Simon, Valeska, Ramirez-Pereira, Mirliana, Rojas, Verónica, Tobar, Eduardo, Landskron, Glauben, Araya, Juan Pablo, Navarrete, Mariela, Bastias, Carla, Tordecilla, Rocío, Varas, Macarena A., Maturana, Pablo, Marcoleta, Andrés E., Allende, Miguel L., Naves, Rodrigo, Hermoso, Marcela A., Salazar-Onfray, Flavio, Lopez, Mercedes, Bono, María Rosa, Osorio, Fabiola

“…The prognosis of severe COVID-19 patients has motivated research communities to uncover mechanisms of SARS-CoV-2 pathogenesis also on a regional level. In this…”
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Metalloproteinase-dependent TLR2 ectodomain shedding is involved in soluble toll-like receptor 2 (sTLR2) production by Langjahr, Patricia, Díaz-Jiménez, David, De la Fuente, Marjorie, Rubio, Estefhany, Golenbock, Douglas, Bronfman, Francisca C, Quera, Rodrigo, González, María-Julieta, Hermoso, Marcela A

“…Toll-like receptor (TLR) 2, a type I membrane receptor that plays a key role in innate immunity, recognizes conserved molecules in pathogens, and triggering an…”
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