Search Results - "HERLITZE, S"
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Spinocerebellar ataxia type 6 protein aggregates cause deficits in motor learning and cerebellar plasticity
Published in The Journal of neuroscience (10-06-2015)“…Spinocerebellar ataxia type 6 (SCA6) is linked to poly-glutamine (polyQ) within the C terminus (CT) of the pore-forming subunits of P/Q-type Ca(2+) channels…”
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2
The IsoStretcher: An isotropic cell stretch device to study mechanical biosensor pathways in living cells
Published in Biosensors & bioelectronics (15-07-2016)“…Mechanosensation in many organs (e.g. lungs, heart, gut) is mediated by biosensors (like mechanosensitive ion channels), which convert mechanical stimuli into…”
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3
G‐protein mediated gating of inward‐rectifier K+ channels
Published in European journal of biochemistry (01-10-2000)“…G‐protein regulated inward‐rectifier potassium channels (GIRK) are part of a superfamily of inward‐rectifier K+ channels which includes seven family members…”
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4
G protein modulation of recombinant P/Q-type calcium channels by regulators of G protein signalling proteins
Published in The Journal of physiology (01-10-2000)“…Fast synaptic transmission is triggered by the activation of presynaptic Ca 2+ channels which can be inhibited by Gβγ subunits via G protein-coupled…”
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5
Argiotoxin detects molecular differences in AMPA receptor channels
Published in Neuron (Cambridge, Mass.) (01-06-1993)“…Argiotoxin, a component of the spider venom from Argiope lobata, blocks AMPA receptor channels expressed in homomeric and heteromeric configuration in Xenopus…”
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6
P107. Physiological mechanisms of cerebellar transcranial direct current stimulation in humans
Published in Clinical neurophysiology (01-08-2018)“…Recently, transcranial direct current stimulation (tDCS) became a popular method to non-invasively modulate cerebellar excitability and help us broaden our…”
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7
Structural determinants of channel conductance in fetal and adult rat muscle acetylcholine receptors
Published in The Journal of physiology (01-05-1996)“…1. The structural basis of the developmentally regulated increase in endplate channel conductance in rat, where the gamma-subunit of the fetal muscle…”
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Location of a Threonine Residue in the $\alpha $-subunit M2 Transmembrane Segment that Determines the Ion Flow through the Acetylcholine Receptor Channel
Published in Proceedings of the Royal Society. B, Biological sciences (22-01-1991)“…By the combination of cDNA manipulation and functional analysis of normal and mutant acetylcholine receptor (AChR) channels of Torpedo expressed in Xenopus…”
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9
Short antisense oligonucleotide-mediated inhibition is strongly dependent on oligo length and concentration but almost independent of location of the target sequence
Published in The Journal of biological chemistry (10-06-1994)“…The inhibitory effect of short antisense oligodeoxynucleotides (aODNs) on cRNA expression in Xenopus oocytes was measured using an electrophysiological assay…”
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10
Asymmetry of the Rat Acetylcholine Receptor Subunits in the Narrow Region of the Pore
Published in Proceedings of the Royal Society. B, Biological sciences (22-09-1992)“…The acetylcholine receptor (AChR) channel is a pentameric protein in which every subunit contributes to the conducting parts of the pore. Recent studies of rat…”
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11
Serotonin neurons in the dorsal raphe mediate the anticataplectic action of orexin neurons by reducing amygdala activity
Published in Sleep medicine (01-12-2017)Get full text
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12
A Genetic Approach to Access Serotonin Neurons for in vivo and in vitro Studies
Published in Proceedings of the National Academy of Sciences - PNAS (08-11-2005)“…Serotonin (5HT) is a critical modulator of neural circuits that support diverse behaviors and physiological processes, and multiple lines of evidence implicate…”
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13
Modulation of Ca2+ channels by G-protein beta gamma subunits
Published in Nature (London) (21-03-1996)“…Calcium ions entering cells through voltage-gated Ca2+ channels initiate rapid release of neurotransmitters and secretion of hormones. Ca2+ currents can be…”
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14
Molecular basis of inward rectification: polyamine interaction sites located by combined channel and ligand mutagenesis
Published in The Journal of general physiology (01-11-2004)“…Polyamines cause inward rectification of (Kir) K+ channels, but the mechanism is controversial. We employed scanning mutagenesis of Kir6.2, and a structural…”
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15
A general and rapid mutagenesis method using polymerase chain reaction
Published in Gene (02-07-1990)“…The construction of deletions, insertions and point mutations in DNA sequences is a powerful approach to analysing the function and structure of genes and…”
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New roles for RGS2, 5 and 8 on the ratio-dependent modulation of recombinant GIRK channels expressed in Xenopus oocytes
Published in The Journal of physiology (01-06-1999)“…The activation of G protein-regulated inward rectifying potassium (GIRK) channels is modulated by G protein-coupled receptors (GPCRs) via the G protein βγ…”
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17
Allosteric modulation of Ca super(2+) channels by G proteins, voltage-dependent facilitation, protein kinase C, and Ca sub(v) beta subunits
Published in Proceedings of the National Academy of Sciences - PNAS (10-04-2001)“…N-type and P/Q-type Ca super(2+) channels are inhibited by neurotransmitters acting through G protein-coupled receptors in a membrane-delimited pathway…”
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18
Allosteric modulation of Ca2+ channels by G proteins, voltage-dependent facilitation, protein kinase C, and Ca(v)beta subunits
Published in Proceedings of the National Academy of Sciences - PNAS (10-04-2001)“…N-type and P/Q-type Ca(2+) channels are inhibited by neurotransmitters acting through G protein-coupled receptors in a membrane-delimited pathway involving…”
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19
Competitive and Synergistic Interactions of G Protein beta sub(2) and Ca super(2+) Channel beta sub(1b) Subunits with Ca sub(v)2.1 Channels, Revealed by Mammalian Two-hybrid and Fluorescence Resonance Energy Transfer Measurements
Published in The Journal of biological chemistry (05-12-2003)“…Presynaptic Ca super(2+) channels are inhibited by metabotropic receptors. A possible mechanism for this inhibition is that G protein beta gamma subunits…”
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20
Targeting mechanisms of high voltage-activated Ca2+ channels
Published in Journal of bioenergetics and biomembranes (01-12-2003)“…Functional voltage-dependent Ca2+ channel complexes are assembled by three to four subunits: alpha1, beta, alpha2delta subunits (C. Leveque et al., 1994, J…”
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