Search Results - "HERBERT, Ronald"
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1
The mutational signature profile of known and suspected human carcinogens in mice
Published in Nature genetics (01-11-2020)“…Epidemiological studies have identified many environmental agents that appear to significantly increase cancer risk in human populations. By analyzing tumor…”
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2
Immunohistochemistry in Investigative and Toxicologic Pathology
Published in Toxicologic Pathology (01-07-2018)“…Immunohistochemistry (IHC) is a valuable tool in pathology. This review provides a brief description of the technical aspects of IHC and a detailed discussion…”
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Book Review Journal Article -
3
Nonproliferative and Proliferative Lesions of the Rat and Mouse Hematolymphoid System
Published in Toxicologic pathology (01-08-2019)“…The INHAND Project (International Harmonization of Nomenclature and Diagnostic Criteria for Lesions in Rats and Mice) is a joint initiative of the Societies of…”
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4
Recommendations from the INHAND Apoptosis/Necrosis Working Group
Published in Toxicologic pathology (01-02-2016)“…Historically, there has been confusion relating to the diagnostic nomenclature for individual cell death. Toxicologic pathologists have generally used the…”
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5
Nonproliferative and Proliferative Lesions of the Rat and Mouse Female Reproductive System
Published in Journal of Toxicologic Pathology (01-01-2014)“…The INHAND (International Harmonization of Nomenclature and Diagnostic Criteria for Lesions in Rats and Mice) Project (www.toxpath.org/inhand.asp) is a joint…”
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6
Comparative toxicity and carcinogenicity of soluble and insoluble cobalt compounds
Published in Toxicology (Amsterdam) (03-07-2015)“…Abstract Occupational exposure to cobalt is of widespread concern due to its use in a variety of industrial processes and the occurrence of occupational…”
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7
Hexavalent Chromium Is Carcinogenic to F344/N Rats and B6C3F1 Mice after Chronic Oral Exposure
Published in Environmental health perspectives (01-05-2009)“…Background: Hexavalent chromium [Cr(VI)] is a human carcinogen after inhalation exposure. Humans also ingest Cr(VI) from contaminated drinking water and soil;…”
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8
Biomarkers of oxidative stress study VI. Endogenous plasma antioxidants fail as useful biomarkers of endotoxin-induced oxidative stress
Published in Free radical biology & medicine (01-04-2015)“…This is the newest report in a series of publications aiming to identify a blood-based antioxidant biomarker that could serve as an in vivo indicator of…”
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9
Cobalt-induced oxidative stress contributes to alveolar/bronchiolar carcinogenesis in B6C3F1/N mice
Published in Archives of toxicology (01-10-2021)“…Rodent alveolar/bronchiolar carcinomas (ABC) that arise either spontaneously or due to chemical exposure are similar to a subtype of lung adenocarcinomas in…”
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10
Mechanistic Insights from the NTP Studies of Chromium
Published in Toxicologic pathology (01-02-2013)“…Hexavalent chromium (Cr(VI)) is a contaminant of water and soil and is a human lung carcinogen. Trivalent chromium (Cr(III)), a proposed essential element, is…”
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11
Whole exome sequencing in the rat
Published in BMC genomics (20-06-2018)“…The rat genome was sequenced in 2004 with the aim to improve human health altered by disease and environmental influences through gene discovery and animal…”
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12
Abrogation of Lupus Nephritis in Activation-Induced Deaminase-Deficient MRL/lpr Mice
Published in Journal of Immunology (01-06-2007)“…We generated MRL/lpr mice deficient in activation-induced deaminase (AID). Because AID is required for Ig hypermutation and class switch recombination, these…”
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13
Glis3 Is Associated with Primary Cilia and Wwtr1/TAZ and Implicated in Polycystic Kidney Disease
Published in Molecular and Cellular Biology (01-05-2009)“…Article Usage Stats Services MCB Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley…”
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14
The National Toxicology Program Web-based Nonneoplastic Lesion Atlas: A Global Toxicology and Pathology Resource
Published in Toxicologic pathology (2014)“…Toxicologists and pathologists worldwide will benefit from a new, website-based, and completely searchable Nonneoplastic Lesion Atlas just released by the U.S…”
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15
Do GISTs Occur in Rats and Mice? Immunohistochemical Characterization of Gastrointestinal Tumors Diagnosed as Smooth Muscle Tumors in The National Toxicology Program
Published in Toxicologic pathology (01-07-2019)“…The majority of the tumors in the gastrointestinal (GI) tract of rats and mice, with spindle cell morphology, are diagnosed as smooth muscle tumors (SMTs)…”
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16
Uterine Paramesonephric Cysts in Sprague-Dawley Rats from National Toxicology Program Studies
Published in Toxicologic pathology (01-06-2018)“…Congenital uterine wall cysts arising from paramesonephric (Müllerian) and mesonephric (Wolffian) ducts are typically incidental findings in most species. We…”
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Hormone Receptor Expression in Spontaneous Uterine Adenocarcinoma in Fischer 344 Rats
Published in Toxicologic pathology (01-08-2015)“…Most uterine cancers, the most common gynecological malignancies in women in developed countries, are hormone-dependent endometrial adenocarcinomas (EACs) that…”
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18
Qualitative and Quantitative Analysis of Nonneoplastic Lesions in Toxicology Studies
Published in Toxicologic pathology (01-01-2002)“…A pathology report is written to convey information concerning the pathologic findings in a study. This type of report must be complete, accurate and…”
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Histopathological and Immunohistochemical Characterization of Methyl Eugenol–induced Nonneoplastic and Neoplastic Neuroendocrine Cell Lesions in Glandular Stomach of Rats
Published in Toxicologic pathology (01-07-2015)“…Methyl eugenol induces neuroendocrine (NE) cell hyperplasia and tumors in F344/N rat stomach. Detailed histopathological and immunohistochemical (IHC)…”
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Kras, Egfr, and Tp53 Mutations in B6C3F1/N Mouse and F344/NTac Rat Alveolar/Bronchiolar Carcinomas Resulting from Chronic Inhalation Exposure to Cobalt Metal
Published in Toxicologic pathology (01-08-2015)“…Rodent lung tumors are morphologically similar to a subtype of human lung adenocarcinomas. The objective of this study was to evaluate Kirsten rat sarcoma…”
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