Search Results - "HENDRIKS, Gert"

Single-cell RNA counting at allele and isoform resolution using Smart-seq3 by Hagemann-Jensen, Michael, Ziegenhain, Christoph, Chen, Ping, Ramsköld, Daniel, Hendriks, Gert-Jan, Larsson, Anton J. M., Faridani, Omid R., Sandberg, Rickard

“…Large-scale sequencing of RNA from individual cells can reveal patterns of gene, isoform and allelic expression across cell types and states 1 . However,…”
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Developmental function and state transitions of a gene expression oscillator in Caenorhabditis elegans by Meeuse, Milou WM, Hauser, Yannick P, Morales Moya, Lucas J, Hendriks, Gert‐Jan, Eglinger, Jan, Bogaarts, Guy, Tsiairis, Charisios, Großhans, Helge

“…Gene expression oscillators can structure biological events temporally and spatially. Different biological functions benefit from distinct oscillator…”
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NASC-seq monitors RNA synthesis in single cells by Hendriks, Gert-Jan, Jung, Lisa A., Larsson, Anton J. M., Lidschreiber, Michael, Andersson Forsman, Oscar, Lidschreiber, Katja, Cramer, Patrick, Sandberg, Rickard

“…Sequencing of newly synthesised RNA can monitor transcriptional dynamics with great sensitivity and high temporal resolution, but is currently restricted to…”
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Transcriptional kinetics and molecular functions of long noncoding RNAs by Johnsson, Per, Ziegenhain, Christoph, Hartmanis, Leonard, Hendriks, Gert-Jan, Hagemann-Jensen, Michael, Reinius, Björn, Sandberg, Rickard

“…An increasing number of long noncoding RNAs (lncRNAs) have experimentally confirmed functions, yet little is known about their transcriptional dynamics and it…”
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Repetitive transcranial magnetic stimulation for obsessive-compulsive disorder: A systematic review and pairwise/network meta-analysis by Fitzsimmons, Sophie M.D.D., van der Werf, Ysbrand D., van Campen, A. Dilene, Arns, Martijn, Sack, Alexander T., Hoogendoorn, Adriaan W., van Balkom, Anton J.L.M., Batelaan, Neeltje M., Eijndhoven, Philip van, Hendriks, Gert-Jan, Oostrom, Iris van, Oppena, Patricia van, Schruers, Koen R.J., Tendolkar, Indira, Vriend, Chris, van den Heuvel, Odile A.

“…•We identify 3 specific, efficacious stimulation location/frequency combinations.•Low frequency rTMS to the pre-supplementary motor area.•High frequency rTMS…”
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Intensive prolonged exposure treatment for adolescent complex posttraumatic stress disorder: a single‐trial design by Hendriks, Lotte, Kleine, Rianne A., Heyvaert, Mieke, Becker, Eni S., Hendriks, Gert‐Jan, Minnen, Agnes

“…Background The current study evaluated the effectiveness and safety of intensive prolonged exposure (PE) targeting adolescent patients with complex…”
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A Randomized Placebo-Controlled Trial of d -Cycloserine to Enhance Exposure Therapy for Posttraumatic Stress Disorder by de Kleine, Rianne A, Hendriks, Gert-Jan, Kusters, Wendy J.C, Broekman, Theo G, van Minnen, Agnes

“…Background Posttraumatic stress disorder (PTSD) is a complex and debilitating anxiety disorder, and, although prolonged exposure therapy has been proven…”
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Depressive symptomatology in older adults treated with behavioral activation: A network perspective by Janssen, Noortje P., Guineau, Melissa G., Lucassen, Peter, Hendriks, Gert-Jan, Ikani, Nessa

“…Late-life depression is a serious mental health problem. Behavioral Activation (BA) is an effective, accessible psychotherapeutic treatment for older adults…”
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The microRNA miR-34 modulates ageing and neurodegeneration in Drosophila by Liu, Nan, Landreh, Michael, Cao, Kajia, Abe, Masashi, Hendriks, Gert-Jan, Kennerdell, Jason R., Zhu, Yongqing, Wang, Li-San, Bonini, Nancy M.

“…The conserved microRNA miR-34 regulates age-associated events and long-term brain integrity in Drosophila , providing a molecular link between ageing and…”
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The exonuclease Nibbler regulates age‐associated traits and modulates piRNA length in Drosophila by Feltzin, Virzhiniya L., Khaladkar, Mugdha, Abe, Masashi, Parisi, Michael, Hendriks, Gert‐Jan, Kim, Junhyong, Bonini, Nancy M.

“…Summary Nibbler (Nbr) is a 3′‐to‐5′ exonuclease that trims the 3′end of microRNAs (miRNAs) to generate different length patterns of miRNAs in Drosophila…”
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Molecular spikes: a gold standard for single-cell RNA counting by Ziegenhain, Christoph, Hendriks, Gert-Jan, Hagemann-Jensen, Michael, Sandberg, Rickard

“…Single-cell sequencing methods rely on molecule-counting strategies to account for amplification biases, yet no experimental strategy to evaluate counting…”
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D-Cycloserine Augmentation of Exposure-Based Cognitive Behavior Therapy for Anxiety, Obsessive-Compulsive, and Posttraumatic Stress Disorders: A Systematic Review and Meta-analysis of Individual Participant Data by Mataix-Cols, David, Fernández de la Cruz, Lorena, Monzani, Benedetta, Rosenfield, David, Andersson, Erik, Pérez-Vigil, Ana, Frumento, Paolo, de Kleine, Rianne A, Difede, JoAnn, Dunlop, Boadie W, Farrell, Lara J, Geller, Daniel, Gerardi, Maryrose, Guastella, Adam J, Hofmann, Stefan G, Hendriks, Gert-Jan, Kushner, Matt G, Lee, Francis S, Lenze, Eric J, Levinson, Cheri A, McConnell, Harry, Otto, Michael W, Plag, Jens, Pollack, Mark H, Ressler, Kerry J, Rodebaugh, Thomas L, Rothbaum, Barbara O, Scheeringa, Michael S, Siewert-Siegmund, Anja, Smits, Jasper A J, Storch, Eric A, Ströhle, Andreas, Tart, Candyce D, Tolin, David F, van Minnen, Agnes, Waters, Allison M, Weems, Carl F, Wilhelm, Sabine, Wyka, Katarzyna, Davis, Michael, Rück, Christian, Altemus, Margaret, Anderson, Page, Cukor, Judith, Finck, Claudia, Geffken, Gary R, Golfels, Fabian, Goodman, Wayne K, Gutner, Cassidy, Heyman, Isobel, Jovanovic, Tanja, Lewin, Adam B, McNamara, Joseph P, Murphy, Tanya K, Norrholm, Seth, Thuras, Paul

“…Whether and under which conditions D-cycloserine (DCS) augments the effects of exposure-based cognitive behavior therapy for anxiety, obsessive-compulsive, and…”
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Lower versus higher frequency of sessions in starting outpatient mental health care and the risk of a chronic course; a naturalistic cohort study by Tiemens, Bea, Kloos, Margot, Spijker, Jan, Ingenhoven, Theo, Kampman, Mirjam, Hendriks, Gert-Jan

“…An adequate frequency of treatment might be a prerequisite for a favorable outcome. Unfortunately, there is a diversity of factors that interfere with an…”
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Age related differences in symptom networks of overall psychological functioning in a sample of patients diagnosed with anxiety, obsessive compulsive disorder, or posttraumatic stress disorder by Guineau, Melissa G, Ikani, Nessa, Tiemens, Bea, Oude Voshaar, Richard, Fokkema, Marjolein, Hendriks, Gert-Jan

“…Anxiety disorders, obsessive compulsive disorder (OCD), and posttraumatic stress disorder (PTSD) are among the most prevalent mental disorders across the…”
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Cost-effectiveness of behavioral activation compared to treatment as usual for depressed older adults in primary care: A cluster randomized controlled trial by Janssen, Noortje P., Hendriks, Gert-Jan, Sens, Renate, Lucassen, Peter, Oude Voshaar, Richard C., Ekers, David, van Marwijk, Harm, Spijker, Jan, Bosmans, Judith E.

“…Depression in older adults is associated with decreased quality of life and increased utilization of healthcare services. Behavioral activation (BA) is an…”
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The Exoribonuclease Nibbler Controls 3′ End Processing of MicroRNAs in Drosophila by Liu, Nan, Abe, Masashi, Sabin, Leah R., Hendriks, Gert-Jan, Naqvi, Ammar S., Yu, Zhenming, Cherry, Sara, Bonini, Nancy M.

“…MicroRNAs (miRNAs) are endogenous noncoding small RNAs with important roles in many biological pathways; their generation and activity are under precise…”
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Impact of age-associated increase in 2'-O-methylation of miRNAs on aging and neurodegeneration in Drosophila by Abe, Masashi, Naqvi, Ammar, Hendriks, Gert-Jan, Feltzin, Virzhiniya, Zhu, Yongqing, Grigoriev, Andrey, Bonini, Nancy M

“…MicroRNAs (miRNAs) are 20- to ∼24-nucleotide (nt) small RNAs that impact a variety of biological processes, from development to age-associated events. To study…”
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Dynamics of miRNA accumulation during C. elegans larval development by Nahar, Smita, Morales Moya, Lucas J, Brunner, Jana, Hendriks, Gert-Jan, Towbin, Benjamin, Hauser, Yannick P, Brancati, Giovanna, Gaidatzis, Dimos, Großhans, Helge

“…Temporally and spatially controlled accumulation underlies the functions of microRNAs (miRNAs) in various developmental processes. In Caenorhabditis elegans,…”
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The enhancing effects of testosterone in exposure treatment for social anxiety disorder: a randomized proof-of-concept trial by Hutschemaekers, Moniek H. M., de Kleine, Rianne A., Hendriks, Gert-Jan, Kampman, Mirjam, Roelofs, Karin

“…Individuals with a social anxiety disorder (SAD) show hypofunctioning of the hypothalamus–pituitary-gonadal (HPG) axis, which is linked to social fear and…”
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Intensive prolonged exposure therapy for chronic PTSD patients following multiple trauma and multiple treatment attempts by Hendriks, Lotte, Kleine, Rianne A. de, Broekman, Theo G., Hendriks, Gert-Jan, Minnen, Agnes van

“…Background: Suboptimal response and high dropout rates leave room for improvement of trauma-focused treatment (TFT) effectiveness in ameliorating posttraumatic…”
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