Search Results - "HENDERSON, Jaimie M"
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High-performance brain-to-text communication via handwriting
Published in Nature (London) (13-05-2021)“…Brain–computer interfaces (BCIs) can restore communication to people who have lost the ability to move or speak. So far, a major focus of BCI research has been…”
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Optical Deconstruction of Parkinsonian Neural Circuitry
Published in Science (American Association for the Advancement of Science) (17-04-2009)“…Deep brain stimulation (DBS) is a therapeutic option for intractable neurological and psychiatric disorders, including Parkinson's disease and major…”
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High performance communication by people with paralysis using an intracortical brain-computer interface
Published in eLife (21-02-2017)“…Brain-computer interfaces (BCIs) have the potential to restore communication for people with tetraplegia and anarthria by translating neural activity into…”
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Long-term efficacy and safety of thalamic stimulation for drug-resistant partial epilepsy
Published in Neurology (10-03-2015)“…OBJECTIVE:To report long-term efficacy and safety results of the SANTE trial investigating deep brain stimulation of the anterior nucleus of the thalamus (ANT)…”
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Clinical translation of a high-performance neural prosthesis
Published in Nature medicine (01-10-2015)“…An intracortical neural prosthetic system developed in animal studies is translated for clinical use in humans with paralysis. Neural control of computer…”
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Beta oscillations in freely moving Parkinson's subjects are attenuated during deep brain stimulation
Published in Movement disorders (01-11-2015)“…Background Investigations into the effect of deep brain stimulation (DBS) on subthalamic (STN) beta (13‐30 Hz) oscillations have been performed in the…”
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"Connectomic surgery": diffusion tensor imaging (DTI) tractography as a targeting modality for surgical modulation of neural networks
Published in Frontiers in integrative neuroscience (01-01-2012)“…Deep brain stimulation (DBS) is being used to treat a growing number of neurological disorders. Until recently, DBS has been thought to act mainly by…”
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Cortical control of a tablet computer by people with paralysis
Published in PloS one (21-11-2018)“…General-purpose computers have become ubiquitous and important for everyday life, but they are difficult for people with paralysis to use. Specialized software…”
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Altered sense of self during seizures in the posteromedial cortex
Published in Proceedings of the National Academy of Sciences - PNAS (20-07-2021)“…The posteromedial cortex (PMC) is known to be a core node of the default mode network. Given its anatomical location and blood supply pattern, the effects of…”
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A prospective trial of magnetic resonance–guided focused ultrasound thalamotomy for essential tremor: Results at the 2‐year follow‐up
Published in Annals of neurology (01-01-2018)“…Objective Magnetic resonance guided focused ultrasound (MRgFUS) has recently been investigated as a new treatment modality for essential tremor (ET), but the…”
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High frequency deep brain stimulation attenuates subthalamic and cortical rhythms in Parkinson's disease
Published in Frontiers in human neuroscience (04-06-2012)“…Parkinson's disease (PD) is marked by excessive synchronous activity in the beta (8-35 Hz) band throughout the cortico-basal ganglia network. The optimal…”
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Gene delivery of neurturin to putamen and substantia nigra in Parkinson disease: A double-blind, randomized, controlled trial
Published in Annals of neurology (01-08-2015)“…Objective A 12‐month double‐blind sham‐surgery–controlled trial assessing adeno‐associated virus type 2 (AAV2)‐neurturin injected into the putamen bilaterally…”
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Impact of skull density ratio on efficacy and safety of magnetic resonance-guided focused ultrasound treatment of essential tremor
Published in Journal of neurosurgery (01-05-2020)“…Skull density ratio (SDR) assesses the transparency of the skull to ultrasound. Magnetic resonance-guided focused ultrasound (MRgFUS) thalamotomy in essential…”
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14
Patient-specific analysis of the volume of tissue activated during deep brain stimulation
Published in NeuroImage (Orlando, Fla.) (15-01-2007)“…Despite the clinical success of deep brain stimulation (DBS) for the treatment of movement disorders, many questions remain about its effects on the nervous…”
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AAV2- GAD gene therapy for advanced Parkinson's disease: a double-blind, sham-surgery controlled, randomised trial
Published in Lancet neurology (01-04-2011)“…Summary Background Gene transfer of glutamic acid decarboxylase ( GAD ) and other methods that modulate production of GABA in the subthalamic nucleus improve…”
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Brain control of bimanual movement enabled by recurrent neural networks
Published in Scientific reports (18-01-2024)“…Brain-computer interfaces have so far focused largely on enabling the control of a single effector, for example a single computer cursor or robotic arm…”
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Advanced neurotechnologies for chronic neural interfaces: new horizons and clinical opportunities
Published in The Journal of neuroscience (12-11-2008)Get full text
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The STN beta-band profile in Parkinson's disease is stationary and shows prolonged attenuation after deep brain stimulation
Published in Experimental neurology (2009)“…Producing accurate movements may rely on the functional independence of sensorimotor circuits within basal ganglia nuclei. In parkinsonism there is abnormal…”
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Alpha-synuclein suppression by targeted small interfering RNA in the primate substantia nigra
Published in PloS one (11-08-2010)“…The protein alpha-synuclein is involved in the pathogenesis of Parkinson's disease and other neurodegenerative disorders. Its toxic potential appears to be…”
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Neural ensemble dynamics in dorsal motor cortex during speech in people with paralysis
Published in eLife (10-12-2019)“…Speaking is a sensorimotor behavior whose neural basis is difficult to study with single neuron resolution due to the scarcity of human intracortical…”
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