Search Results - "HENDERSON, J. P."

Phosphorylation of cAMP-specific PDE4A5 (phosphodiesterase-4A5) by MK2 (MAPKAPK2) attenuates its activation through protein kinase A phosphorylation by MacKenzie, Kirsty F, Wallace, Derek A, Hill, Elaine V, Anthony, Diana F, Henderson, David J P, Houslay, Daniel M, Arthur, J Simon C, Baillie, George S, Houslay, Miles D

“…cAMP-specific PDE (phosphodiesterase) 4 isoforms underpin compartmentalized cAMP signalling in mammalian cells through targeting to specific signalling…”
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Vancomycin resistance has no influence on outcomes of enterococcal bacteriuria by Khair, H.N, VanTassell, P, Henderson, J.P, Warren, D.K, Marschall, J

“…Summary Background Infections with vancomycin-resistant enterococci (VRE) are a growing concern in hospitals. The impact of vancomycin resistance in…”
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Small-molecule allosteric activators of PDE4 long form cyclic AMP phosphodiesterases by Omar, Faisa, Findlay, Jane E., Carfray, Gemma, Allcock, Robert W., Jiang, Zhong, Moore, Caitlin, Muir, Amy L., Lannoy, Morgane, Fertig, Bracy A., Mai, Deborah, Day, Jonathan P., Bolger, Graeme, Baillie, George S., Schwiebert, Erik, Klussmann, Enno, Pyne, Nigel J., Ong, Albert C. M., Bowers, Keith, Adam, Julia M., Adams, David R., Houslay, Miles D., Henderson, David J. P.

“…Cyclic AMP (cAMP) phosphodiesterase-4 (PDE4) enzymes degrade cAMP and underpin the compartmentalization of cAMP signaling through their targeting to particular…”
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Weekend diagnosis of Escherichia coli urinary tract infection does not predict poor outcome by ECHAIZ, J. F., HENDERSON, J. P., WARREN, D. K., MARSCHALL, J.

“…It has been suggested that mortality is higher in patients admitted to hospitals during the weekend. The objective of this study was to compare outcomes in…”
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8-Nitro-2‘-deoxyguanosine, a Specific Marker of Oxidation by Reactive Nitrogen Species, Is Generated by the Myeloperoxidase−Hydrogen Peroxide−Nitrite System of Activated Human Phagocytes by Byun, J, Henderson, J. P, Mueller, D. M, Heinecke, J. W

“…Reactive intermediates generated by phagocytes damage DNA and may contribute to the link between chronic inflammation and cancer. Myeloperoxidase, a heme…”
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The cAMP phosphodiesterase-4D7 (PDE4D7) is downregulated in androgen-independent prostate cancer cells and mediates proliferation by compartmentalising cAMP at the plasma membrane of VCaP prostate cancer cells by Henderson, D J P, Byrne, A, Dulla, K, Jenster, G, Hoffmann, R, Baillie, G S, Houslay, M D

“…Background: Isoforms of the PDE4 family of cAMP-specific phosphodiesterases (PDEs) are expressed in a cell type-dependent manner and contribute to underpinning…”
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Inferior Capsular Shift Procedure in Athletes with Multidirectional Instability Based on Isolated Capsular and Ligamentous Redundancy by Bak, Klaus, Spring, Blake J., Henderson, Ian J. P.

“…Twenty-five athletes (26 shoulders) who underwent an inferior capsular shift procedure for multidirectional glenohumeral instability based on isolated capsular…”
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Antecedent use of fluoroquinolones is associated with resistance to moxifloxacin in Clostridium difficile by Ackermann, G., Tang-Feldman, Y.J., Schaumann, R., Henderson, J.P., Rodloff, A.C., Silva Jr, J., Cohen, S.H.

“…Moxifloxacin is characterized by high activity against Gram-positive cocci and some Gram-positive and -negative anaerobes, including Clostridium difficile…”
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The use of DNA statistics in criminal trials by Henderson, J.P

“…In a number of recent cases in the UK, convictions have been quashed by the Court of Appeal on the grounds that the jury had been misdirected as to the factual…”
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Both Host and Pathogen Factors Predispose to Escherichia coli Urinary-Source Bacteremia in Hospitalized Patients by Marschall, Jonas, Zhang, Lixin, Foxman, Betsy, Warren, David K., Henderson, Jeffrey P.

“…Background. The urinary tract is the most common source for Escherichia coli bacteremia. Mortality from E. coli urinary-source bacteremia is higher than that…”
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Purification and Reconstitution of an Osmosensor:  Transporter ProP of Escherichia coli Senses and Responds to Osmotic Shifts by Racher, K. I, Voegele, R. T, Marshall, E. V, Culham, D. E, Wood, J. M, Jung, H, Bacon, M, Cairns, M. T, Ferguson, S. M, Liang, W.-J, Henderson, P. J. F, White, G, Hallett, F. R

“…The ProP protein of Escherichia coli is an osmoregulatory H+-compatible solute cotransporter. ProP is activated by an osmotic upshift in both whole cells and…”
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Low temperature creep ductility of OFHC copper by Henderson, P.J., Sandström, R.

“…Creep tests have been carried out on oxygen-free high conductivity (OFHC) copper between 75 and 245°C. Two of the batches exhibited poor ductility at…”
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Odontoid fractures in elderly patients by HANIGAN, W. C, POWELL, F. C, ELWOOD, P. W, HENDERSON, J. P

“…This retrospective analysis describes the clinical characteristics, treatment, and outcome of 19 patients aged 80 years or older with odontoid fractures. The…”
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The Eosinophil Peroxidase-Hydrogen Peroxide-Bromide System of Human Eosinophils Generates 5-Bromouracil, a Mutagenic Thymine Analogue by Henderson, Jeffrey P, Byun, Jaeman, Mueller, Dianne M, Heinecke, Jay W

“…Eosinophils use eosinophil peroxidase, hydrogen peroxide (H2O2), and bromide ion (Br-) to generate hypobromous acid (HOBr), a brominating intermediate. This…”
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Bromination of Deoxycytidine by Eosinophil Peroxidase: A Mechanism for Mutagenesis by Oxidative Damage of Nucleotide Precursors by Henderson, Jeffrey P., Byun, Jaeman, Williams, Michelle V., McCormick, Michael L., Parks, William C., Ridnour, Lisa A., Heinecke, Jay W.

“…Oxidants generated by eosinophils during chronic inflammation may lead to mutagenesis in adjacent epithelial cells. Eosinophil peroxidase, a heme enzyme…”
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Growth of pores during the creep of a single crystal nickel-base superalloy by Komenda, J., Henderson, P.J.

“…During creep at 950 deg C in the alloy CMSX-4 there was a marked increase in the number of pores measured from 200 mm exp -2 at zero strain to 60 mm exp -2 at…”
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Corrosion of TP347H FG stainless steel in a biomass fired PF utility boiler by LIU, C, LITTLE, J. A, HENDERSON, P. J, LJUNG, Per

“…Detailed microscopic examinations have been conducted on two, temperature-regulated probes which had been exposed to biomass flue gas inside a PF boiler for…”
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Mitotic activation of the DISC1-inducible cyclic AMP phosphodiesterase-4D9 (PDE4D9), through multi-site phosphorylation, influences cell cycle progression by Sheppard, Catherine L., Lee, Louisa C.Y., Hill, Elaine V., Henderson, David J.P., Anthony, Diana F., Houslay, Daniel M., Yalla, Krishna C., Cairns, Lynne S., Dunlop, Allan J., Baillie, George S., Huston, Elaine, Houslay, Miles D.

“…In Rat-1 cells, the dramatic decrease in the levels of both intracellular cyclic 3′5′ adenosine monophosphate (cyclic AMP; cAMP) and in the activity of…”
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Traumatic peroneal tendon instability by Mason, R B, Henderson, J P

“…To investigate the causes of, pathologic changes associated with, and treatment results after traumatic peroneal tendon subluxation or dislocation, we reviewed…”
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Homologous Sugar Transport Proteins in Escherichia coli and Their Relatives in Both Prokaryotes and Eukaryotes by Henderson, P. J. F., Maiden, M. C. J.

“…Separate proteins for proton-linked transport of D-xylose, L-arabinose, D-galactose, L-rhamnose and L-fucose into Escherichia coli are being studied. By…”
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