Search Results - "HEMPHILL, Andrew"

Effects of negative air ions (NAIs) on Leishmania major: A novel tool for treatment of zoonotic cutaneous leishmaniasis (ZCL) by Badirzadeh, Alireza, Najm, Mehdi, Hemphill, Andrew, Alipour, Maryam, Hasanpour, Hamid, Masoori, Leila, Karimi, Poorya

“…Background Cutaneous leishmaniasis (CL) is a Neglected Tropical Disease (NTD) that causes high morbidity in the tropics and sub-tropics. Despite the remarkable…”
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Comparative Pathobiology of the Intestinal Protozoan Parasites Giardia lamblia , Entamoeba histolytica , and Cryptosporidium parvum by Hemphill, Andrew, Müller, Norbert, Müller, Joachim

“…Protozoan parasites can infect the human intestinal tract causing serious diseases. In the following article, we focused on the three most prominent intestinal…”
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Treatment of echinococcosis: albendazole and mebendazole – what else? by Hemphill, Andrew, Stadelmann, Britta, Rufener, Reto, Spiliotis, Markus, Boubaker, Ghalia, Müller, Joachim, Müller, Norbert, Gorgas, Daniela, Gottstein, Bruno

“…The search for novel therapeutic options to cure alveolar echinococcosis (AE), due to the metacestode of Echinococcus multilocularis, is ongoing, and these…”
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Single- and duplex TaqMan-quantitative PCR for determining the copy numbers of integrated selection markers during site-specific mutagenesis in Toxoplasma gondii by CRISPR-Cas9 by Hänggeli, Kai Pascal Alexander, Hemphill, Andrew, Müller, Norbert, Schimanski, Bernd, Olias, Philipp, Müller, Joachim, Boubaker, Ghalia

“…Herein, we developed a single and a duplex TaqMan quantitative PCR (qPCR) for absolute quantification of copy numbers of integrated dihydrofolate…”
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Resistance to the larvicide temephos and altered egg and larval surfaces characterize salinity-tolerant Aedes aegypti by Sivabalakrishnan, Kokila, Thanihaichelvan, Murugathas, Tharsan, Annathurai, Eswaramohan, Thamboe, Ravirajan, Punniamoorthy, Hemphill, Andrew, Ramasamy, Ranjan, Surendran, Sinnathamby N.

“…Aedes aegypti , the principal global vector of arboviral diseases and previously considered to oviposit and undergo preimaginal development only in fresh…”
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Drug repurposing applied: Activity of the anti-malarial mefloquine against Echinococcus multilocularis by Lundström-Stadelmann, Britta, Rufener, Reto, Hemphill, Andrew

“…The current chemotherapeutical treatment against alveolar echinococcosis relies exclusively on benzimidazoles, which are not parasiticidal and can induce…”
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Investigating Antiprotozoal Chemotherapies with Novel Proteomic Tools-Chances and Limitations: A Critical Review by Müller, Joachim, Boubaker, Ghalia, Müller, Norbert, Uldry, Anne-Christine, Braga-Lagache, Sophie, Heller, Manfred, Hemphill, Andrew

“…Identification of drug targets and biochemical investigations on mechanisms of action are major issues in modern drug development. The present article is a…”
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Physiological aspects of nitro drug resistance in Giardia lamblia by Müller, Joachim, Hemphill, Andrew, Müller, Norbert

“…For over 50 years, metronidazole and other nitro compounds such as nitazoxanide have been used as a therapy of choice against giardiasis and more and more…”
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Predatory Potential of Nymphal Odonates on Aedes aegypti Developing in Freshwater and Brackish Water Habitats by Arthiyan, Sivasingham, Eswaramohan, Thampoe, Hemphill, Andrew, Surendran, Sinnathamby Noble

“…, the primary vector of dengue, undergoes preimaginal development in brackish water (BW). However, dengue vector control exclusively targets freshwater (FW)…”
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New Nucleic Base-Tethered Trithiolato-Bridged Dinuclear Ruthenium(II)-Arene Compounds: Synthesis and Antiparasitic Activity by Desiatkina, Oksana, Mösching, Martin, Anghel, Nicoleta, Boubaker, Ghalia, Amdouni, Yosra, Hemphill, Andrew, Furrer, Julien, Păunescu, Emilia

“…Aiming toward compounds with improved anti- activity by exploiting the parasite auxotrophies, a library of nucleobase-tethered trithiolato-bridged dinuclear…”
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Campylobacter portucalensis sp. nov., a new species of Campylobacter isolated from the preputial mucosa of bulls by Silva, Marta Filipa, Pereira, Gonçalo, Carneiro, Carla, Hemphill, Andrew, Mateus, Luísa, Lopes-da-Costa, Luís, Silva, Elisabete

“…A new species of the Campylobacter genus is described, isolated from the preputial mucosa of bulls (Bos taurus). The five isolates obtained exhibit…”
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Dissection of Besnoitia besnoiti intermediate host life cycle stages: From morphology to gene expression by Ramakrishnan, Chandra, Krishnan, Aarti, Francisco, Samuel, Schmid, Marc W, Russo, Giancarlo, Leitão, Alexandre, Hemphill, Andrew, Soldati-Favre, Dominique, Hehl, Adrian B

“…Cyst-forming Apicomplexa (CFA) of the Sarcocystidae have a ubiquitous presence as pathogens of humans and farm animals transmitted through the food chain…”
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Cellular and Molecular Targets of Nucleotide-Tagged Trithiolato-Bridged Arene Ruthenium Complexes in the Protozoan Parasites Toxoplasma gondii and Trypanosoma brucei by Anghel, Nicoleta, Müller, Joachim, Serricchio, Mauro, Jelk, Jennifer, Bütikofer, Peter, Boubaker, Ghalia, Imhof, Dennis, Ramseier, Jessica, Desiatkina, Oksana, Păunescu, Emilia, Braga-Lagache, Sophie, Heller, Manfred, Furrer, Julien, Hemphill, Andrew

“…Toxoplasma gondii is an apicomplexan parasite that infects and proliferates within many different types of host cells and infects virtually all warm-blooded…”
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Echinococcus P29 antigen: molecular characterization and implication on post-surgery follow-up of CE patients infected with different species of the Echinococcus granulosus complex by Boubaker, Ghalia, Gottstein, Bruno, Hemphill, Andrew, Babba, Hamouda, Spiliotis, Markus

“…The protein P29 is a potential serological marker for post-treatment monitoring of cystic echinococcosis (CE) especially in young patients. We now have…”
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Molecular Targets of the 5-Amido-Carboxamide Bumped Kinase Inhibitor BKI-1748 in Cryptosporidium parvum and HCT-8 Host Cells by Ajiboye, Jubilee, Uldry, Anne-Christine, Heller, Manfred, Naguleswaran, Arunasalam, Fan, Erkang, Van Voorhis, Wesley C, Hemphill, Andrew, Müller, Joachim

“…is an apicomplexan parasite causing persistent diarrhea in humans and animals. Issuing from target-based drug development, calcium-dependent protein kinase 1…”
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In Vitro Activities of MMV Malaria Box Compounds against the Apicomplexan Parasite Neospora caninum , the Causative Agent of Neosporosis in Animals by Müller, Joachim, Winzer, Pablo A, Samby, Kirandeep, Hemphill, Andrew

“…(1) Background: is a major cause of abortion in cattle and represents a veterinary health problem of great economic significance. In order to identify novel…”
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Comparative Proteomic Analysis of Toxoplasma gondii RH Wild-Type and Four SRS29B (SAG1) Knock-Out Clones Reveals Significant Differences between Individual Strains by Hänggeli, Kai Pascal Alexander, Hemphill, Andrew, Müller, Norbert, Heller, Manfred, Uldry, Anne-Christine, Braga-Lagache, Sophie, Müller, Joachim, Boubaker, Ghalia

“…In , as well as in other model organisms, gene knock-out using CRISPR-Cas9 is a suitable tool to identify the role of specific genes. The general consensus…”
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Screening of the Open Source Malaria Box Reveals an Early Lead Compound for the Treatment of Alveolar Echinococcosis by Stadelmann, Britta, Rufener, Reto, Aeschbacher, Denise, Spiliotis, Markus, Gottstein, Bruno, Hemphill, Andrew

“…The metacestode (larval) stage of the tapeworm Echinococcus multilocularis causes alveolar echinococcosis (AE), a very severe and in many cases incurable…”
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Synthesis and Antiparasitic Activity of New Trithiolato-Bridged Dinuclear Ruthenium(II)-arene-carbohydrate Conjugates by Holzer, Isabelle, Desiatkina, Oksana, Anghel, Nicoleta, Johns, Serena K, Boubaker, Ghalia, Hemphill, Andrew, Furrer, Julien, Păunescu, Emilia

“…Eight novel carbohydrate-tethered trithiolato dinuclear ruthenium(II)-arene complexes were synthesized using CuAAC ‘click’ (Cu(I)-catalyzed azide-alkyne…”
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Regulation of hepatic microRNAs in response to early stage Echinococcus multilocularis egg infection in C57BL/6 mice by Boubaker, Ghalia, Strempel, Sebastian, Hemphill, Andrew, Müller, Norbert, Wang, Junhua, Gottstein, Bruno, Spiliotis, Markus

“…We present a comprehensive analysis of the hepatic miRNA transcriptome at one month post-infection of experimental primary alveolar echinococcosis (AE), a…”
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