Search Results - "HELMSCHRODT, Christin"

LC–MS-based metabolomics in the clinical laboratory by Becker, Susen, Kortz, Linda, Helmschrodt, Christin, Thiery, Joachim, Ceglarek, Uta

“…The analysis of metabolites in human body fluids remains a challenge because of their chemical diversity and dynamic concentration range. Liquid chromatography…”
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Subtle changes in striatal muscarinic M1 and M4 receptor expression in the DYT1 knock-in mouse model of dystonia by Richter, Franziska, Klein, Laura, Helmschrodt, Christin, Richter, Angelika

“…In early-onset generalized torsion dystonia, caused by a GAG deletion in TOR1A (DYT1), enhanced striatal cholinergic activity has been suggested to be…”
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Sensitive and simultaneous quantification of 16 neurotransmitters and metabolites in murine microdialysate by fast liquid chromatography-tandem mass spectrometry by Becker, Susen, Schulz, Anja, Kreyer, Sophia, Dreßler, Jan, Richter, Angelika, Helmschrodt, Christin

“…The sensitive and simultaneous measurement of multiple neurotransmitters in microdialysate (MD) of freely moving mice is a prerequisite to study neurochemical…”
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Polyethylenimine Nanoparticle-Mediated siRNA Delivery to Reduce α-Synuclein Expression in a Model of Parkinson’s Disease by Helmschrodt, Christin, Höbel, Sabrina, Schöniger, Sandra, Bauer, Anne, Bonicelli, Jana, Gringmuth, Marieke, Fietz, Simone A., Aigner, Achim, Richter, Angelika, Richter, Franziska

“…RNA interference (RNAi)-based strategies that mediate the specific knockdown of target genes by administration of small interfering RNAs (siRNAs) could be…”
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Preanalytical standardization of sphingosine-1-phosphate, sphinganine-1-phosphate and sphingosine analysis in human plasma by liquid chromatography–tandem mass spectrometry by Ceglarek, Uta, Dittrich, Julia, Helmschrodt, Christin, Wagner, Kristin, Nofer, Jerzy-Roch, Thiery, Joachim, Becker, Susen

“…Preanalytical standardization is required for a reliable quantification of the signaling molecules sphingosine-1-phosphate (S1P), sphinganine-1-phosphate…”
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Lineage-Specific Changes in Biomarkers in Great Apes and Humans by Ronke, Claudius, Dannemann, Michael, Halbwax, Michel, Fischer, Anne, Helmschrodt, Christin, Brügel, Mathias, André, Claudine, Atencia, Rebeca, Mugisha, Lawrence, Scholz, Markus, Ceglarek, Uta, Thiery, Joachim, Pääbo, Svante, Prüfer, Kay, Kelso, Janet

“…Although human biomedical and physiological information is readily available, such information for great apes is limited. We analyzed clinical chemical…”
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Effects of a 2-y dietary weight-loss intervention on cholesterol metabolism in moderately obese men by LEICHTLE, Alexander B, HELMSCHRODT, Christin, STUMVOLL, Michael, THIERY, Joachim, FIEDLER, Georg M, CEGLAREK, Uta, SHAI, Iris, HENKIN, Yaakov, SCHWARZFUCHS, Dan, GOLAN, Rachel, GEPNER, Yftach, STAMPFER, Meir J, BLÜHER, Matthias

“…Long-term dietary weight loss results in complex metabolic changes. However, its effect on cholesterol metabolism in obese subjects is still unclear. We…”
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Development of a fast liquid chromatography-tandem mass spectrometry method for simultaneous quantification of neurotransmitters in murine microdialysate by Helmschrodt, Christin, Becker, Susen, Perl, Stefanie, Schulz, Anja, Richter, Angelika

“…The continuous measurement of multiple neurotransmitters in microdialysate of freely moving mice to study neurochemical changes in specific brain regions…”
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Free oxysterols and bile acids including conjugates - Simultaneous quantification in human plasma and cerebrospinal fluid by liquid chromatography-tandem mass spectrometry by Reinicke, Madlen, Schröter, Jenny, Müller-Klieser, Daniel, Helmschrodt, Christin, Ceglarek, Uta

“…A liquid chromatography-electrospray ionization-tandem mass spectrometry (LC-ESI(+)-MS/MS) assay was developed and qualified for analyzing 35 analytes of the…”
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Fast LC–MS/MS analysis of free oxysterols derived from reactive oxygen species in human plasma and carotid plaque by Helmschrodt, Christin, Becker, Susen, Schröter, Jenny, Hecht, Max, Aust, Gabriela, Thiery, Joachim, Ceglarek, Uta

“…A rapid liquid chromatography–tandem mass spectrometric (LC–MS/MS) method was developed and validated for the quantification of reactive oxygen species (ROS)…”
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Free cholesterol, cholesterol precursor and plant sterol levels in atherosclerotic plaques are independently associated with symptomatic advanced carotid artery stenosis by Ceglarek, Uta, Dittrich, Julia, Leopold, Jenny, Helmschrodt, Christin, Becker, Susen, Staab, Holger, Richter, Olaf, Rohm, Silvio, Aust, Gabriela

“…Circulating sterols result either from cholesterol (CH) synthesis or intestinal uptake. They are mainly esterified and can be oxygenated. Sterols accumulate in…”
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The novel adaptive rotating beam test unmasks sensorimotor impairments in a transgenic mouse model of Parkinson’s disease by Gerstenberger, Julia, Bauer, Anne, Helmschrodt, Christin, Richter, Angelika, Richter, Franziska

“…•Female Thy1-aSyn mice express less human alpha-synuclein compared to males.•This could be involved in the lack of motor deficits in female Thy1-aSyn mice.•A…”
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Residue concentration of cefquinome taking into account different milk fractions and comparing the performance of two screening tests by Bachmann, Joana, Helmschrodt, Christin, Richter, Angelika, Bertulat, Sandra, Heuwieser, Wolfgang

“…This Research Communication describes the residue concentration of a dry cow antibiotic in two different milk fractions and describes effects of milk fraction…”
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Quantitative analysis of cefquinome considering different matrix compositions of bovine colostrum and raw milk by Helmschrodt, Christin, Schmidt, Kathrin, Bertulat, Sandra, Klein, Laura, Finnah, Anke, Heuwieser, Wolfgang, Richter, Angelika

“…A robust liquid chromatography-tandem mass spectrometry method was developed and comprehensively validated for the quantification of cefquinome considering the…”
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Fast liquid chromatography combined with mass spectrometry for the analysis of metabolites and proteins in human body fluids by Kortz, Linda, Helmschrodt, Christin, Ceglarek, Uta

“…In the last decade various analytical strategies have been established to enhance separation speed and efficiency in high performance liquid chromatography…”
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First international descriptive and interventional survey for cholesterol and non-cholesterol sterol determination by gas- and liquid-chromatography–Urgent need for harmonisation of analytical methods by Lütjohann, Dieter, Björkhem, Ingemar, Friedrichs, Silvia, Kerksiek, Anja, Lövgren-Sandblom, Anita, Geilenkeuser, Wolf-Jochen, Ahrends, Robert, Andrade, Isabel, Ansorena, Diana, Astiasarán, Iciar, Baila-Rueda, Lucía, Barriuso, Bianca, Becker, Susen, Bretillon, Lionel, Browne, Richard W., Caccia, Claudio, Ceglarek, Uta, Cenarro, Ana, Crick, Peter J., Fauler, Günter, Garcia-Llatas, Guadalupe, Gray, Robert, Griffiths, William J., Gylling, Helena, Harding, Scott, Helmschrodt, Christin, Iuliano, Luigi, Janssen, Hans-Gerd, Jones, Peter, Kaipiainen, Leena, Kannenberg, Frank, Lagarda, María Jesús, Leoni, Valerio, Lottenberg, Ana Maria, MacKay, Dylan S., Matysik, Silke, McDonald, Jeff, Menendez-Carreño, Maria, Myrie, Semone B., Sutti Nunes, Valéria, Ostlund, Richard E., Polisecki, Eliana, Ramos, Fernando, Rideout, Todd C., Schaefer, Ernst J., Schmitz, Gerd, Wang, Yuqin, Zerbinati, Chiara, Diczfalusy, Ulf, Schött, Hans-Frieder

“…[Display omitted] •We initiated international surveys for comparison of cholesterol and NCS analysis.•We are surprised by the very great differences between…”
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Fast liquid chromatography combined with mass spectrometry for the analysis of metabolites and proteins in human body fluids : Advnaces in Analytical Mass Spectrometry by KORTZ, Linda, HELMSCHRODT, Christin, CEGLAREK, Uta

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Effects of a 2-y dietary weight-loss intervention on cholesterol metabolism in moderately obese men1234 by Leichtle, Alexander B, Helmschrodt, Christin, Ceglarek, Uta, Shai, Iris, Henkin, Yaakov, Schwarzfuchs, Dan, Golan, Rachel, Gepner, Yftach, Stampfer, Meir J, Blüher, Matthias, Stumvoll, Michael, Thiery, Joachim, Fiedler, Georg M

“…Background: Long-term dietary weight loss results in complex metabolic changes. However, its effect on cholesterol metabolism in obese subjects is still…”
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Lineage-Specific Changes in Biomarkers in Great Apes and Humans: e0134548 by Ronke, Claudius, Dannemann, Michael, Halbwax, Michel, Fischer, Anne, Helmschrodt, Christin, Bruegel, Mathias, Andre, Claudine, Atencia, Rebeca, Mugisha, Lawrence, Scholz, Markus

“…Although human biomedical and physiological information is readily available, such information for great apes is limited. We analyzed clinical chemical…”
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