Search Results - "HELMKE, Burkhard M"

Stem Cell Marker CD133 Affects Clinical Outcome in Glioma Patients by ZEPPERNICK, Felix, AHMADI, Rezvan, CAMPOS, Benito, DICTUS, Christine, HELMKE, Burkhard M, BECKER, Natalia, LICHTER, Peter, UNTERBERG, Andreas, RADLWIMMER, Bernhard, HEROLD-MENDE, Christel C

“…Purpose: The CD133 antigen has been identified as a putative stem cell marker in normal and malignant brain tissues. In gliomas, it is used to enrich a…”
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Differentiation therapy exerts antitumor effects on stem-like glioma cells by Campos, Benito, Wan, Feng, Farhadi, Mohammad, Ernst, Aurélie, Zeppernick, Felix, Tagscherer, Katrin E, Ahmadi, Rezvan, Lohr, Jennifer, Dictus, Christine, Gdynia, Georg, Combs, Stephanie E, Goidts, Violaine, Helmke, Burkhard M, Eckstein, Volker, Roth, Wilfried, Beckhove, Philipp, Lichter, Peter, Unterberg, Andreas, Radlwimmer, Bernhard, Herold-Mende, Christel

“…Stem-like tumor cells comprise a highly tumorigenic and therapy-resistant tumor subpopulation, which is believed to substantially influence tumor initiation…”
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Angiogenic growth factors in tissue homogenates of HNSCC: expression pattern, prognostic relevance, and interrelationships by Montag, Michael, Dyckhoff, Gerhard, Lohr, Jennifer, Helmke, Burkhard M., Herrmann, Eva, Plinkert, Peter K., Herold‐Mende, Christel

“…Head and neck squamous cell carcinoma has still a poor prognosis. Since angiogenesis is crucial for tumor growth, a better understanding of the potential…”
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Microenvironment‐induced restoration of cohesive growth associated with focal activation of P‐cadherin expression in lobular breast carcinoma metastatic to the colon by Gronewold, Malte, Grote, Isabel, Bartels, Stephan, Christgen, Henriette, Kandt, Leonie D, Brito, Maria Jose, Cserni, Gàbor, Daemmrich, Maximilian E, Fogt, Franz, Helmke, Burkhard M, Hoeve, Natalie, Lang‐Schwarz, Corinna, Vieth, Michael, Wellmann, Axel, Kuehnle, Elna, Kulik, Ulf, Riedel, Gesa, Reineke‐Plaass, Tanja, Lehmann, Ulrich, Koorman, Thijs, Derksen, Patrick WB, Kreipe, Hans, Christgen, Matthias

“…Invasive lobular carcinoma (ILC) is a special breast cancer type characterized by noncohesive growth and E‐cadherin loss. Focal activation of P‐cadherin…”
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High prevalence of amyloid in 150 surgically removed heart valves—a comparison of histological and clinical data reveals a correlation to atheroinflammatory conditions by Kristen, Arnt V, Schnabel, Philipp A, Winter, Bettina, Helmke, Burkhard M, Longerich, Thomas, Hardt, Stefan, Koch, Achim, Sack, Falk-Udo, Katus, Hugo A, Linke, Reinhold P, Dengler, Thomas J

“…Abstract Introduction The prevalence, pathophysiology, and clinical indicators of valvular amyloid deposition have not been clarified yet. Methods One hundred…”
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Endometrial polyps—neoplastic lesions or not? Is it time to close the files? by Bullerdiek, Jörn, Helmke, Burkhard M., Laban, Mohamed

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Deleted in Malignant Brain Tumors 1 is up-regulated in bacterial endocarditis and binds to components of vegetations by Müller, Hanna, MD, Renner, Marcus, PhD, Helmke, Burkhard M., MD, End, Caroline, PhD, Weiss, Christel, PhD, Poeschl, Johannes, MD, Mollenhauer, Jan, PhD

“…Objective Bacterial endocarditis is a frequent infectious cardiac disease, especially in patients with congenital or acquired heart defects. It is…”
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Novel GATA6-FOXO1 fusions in a subset of epithelioid hemangioma by Antonescu, Cristina R., Huang, Shih-Chiang, Sung, Yun-Shao, Zhang, Lei, Helmke, Burkhard M., Kirchner, Martina, Stenzinger, Albrecht, Mechtersheimer, Gunhild

“…The genetic hallmark of epithelioid hemangioma (EH) is the presence of recurrent gene fusions involving FOS and FOSB transcription factors, which occur in…”
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Heparanase Expression at the Invasion Front of Human Head and Neck Cancers and Correlation with Poor Prognosis by BECKHOVE, Philipp, HELMKE, Burkhard M, ZIOUTA, Yvonne, BUCUR, Mariana, DÖRNER, Wolfgang, MOGLER, Carolin, DYCKHOFF, Gerhard, HEROLD-MENDE, Christel

“…Purpose: Head and neck squamous cell carcinomas (HNSCC) are characterized by a poor prognosis due to aggressive, recurrent tumor growth. Expression of the…”
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Malignant transformation of uterine leiomyoma to myxoid leiomyosarcoma after morcellation associated with ALK rearrangement and loss of 14q by Holzmann, Carsten, Saager, Christian, Mechtersheimer, Gunhild, Koczan, Dirk, Helmke, Burkhard M, Bullerdiek, Jörn

“…A 50 year old woman underwent laparoscopic supracervical hysterectomy because of symptomatic fibroids. Histologic examination of samples obtained after…”
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Fibroid explants reveal a higher sensitivity against MDM2-inhibitor nutlin-3 than matching myometrium by Markowski, Dominique N, Helmke, Burkhard M, Radtke, Arlo, Froeb, Jennifer, Belge, Gazanfer, Bartnitzke, Sabine, Wosniok, Werner, Czybulka-Jachertz, Iris, Deichert, Ulrich, Bullerdiek, Jörn

“…Spontaneous cessation of growth is a frequent finding in uterine fibroids. Increasing evidence suggests an important role of cellular senescence in this growth…”
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Deleted in Malignant Brain Tumors 1 (DMBT1) is present in hyaline membranes and modulates surface tension of surfactant by Müller, Hanna, End, Caroline, Renner, Marcus, Helmke, Burkhard M, Gassler, Nikolaus, Weiss, Christel, Hartl, Dominik, Griese, Matthias, Hafner, Mathias, Poustka, Annemarie, Mollenhauer, Jan, Poeschl, Johannes

“…Deleted in Malignant Brain Tumors 1 (DMBT1) is a secreted scavenger receptor cysteine-rich protein that binds various bacteria and is thought to participate in…”
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Elevated DMBT1 levels in neonatal gastrointestinal diseases by Müller, Hanna, Renner, Marcus, Helmke, Burkhard M., Mollenhauer, Jan, Felderhoff-Müser, Ursula

“…Deleted in malignant brain tumor 1 (DMBT1) is involved in innate immunity and epithelial differentiation. Previous studies in adults indicated a strong…”
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Uterine Fibroids: Do We Deal With More Than One Disease? by Markowski, Dominique N, Helmke, Burkhard M, Bartnitzke, Sabine, Löning, Thomas, Bullerdiek, Jörn

“…Uterine fibroids rank among the most frequent symptomatic human tumors at all. Recent data suggest that mutations of the mediator subcomplex 12 gene (MED12)…”
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Expression of SGLT-1 in preneoplastic and neoplastic lesions of the head and neck by Helmke, Burkhard M, Reisser, Christoph, Idzkoe, Mario, Dyckhoff, Gerhard, Herold-Mende, Christel

“…Tumors show an increased glucose uptake that is mediated by glucose transport proteins. We have analyzed the expression of the sodium-dependent glucose…”
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Author Correction: Artificial intelligence unravels interpretable malignancy grades of prostate cancer on histology images by Okyaz Eminaga, Fred Saad, Zhe Tian, Ulrich Wolffgang, Pierre I. Karakiewicz, Véronique Ouellet, Feryel Azzi, Tilmann Spieker, Burkhard M. Helmke, Markus Graefen, Xiaoyi Jiang, Lei Xing, Jorn H. Witt, Dominique Trudel, Sami-Ramzi Leyh-Bannurah

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Artificial intelligence unravels interpretable malignancy grades of prostate cancer on histology images by Okyaz Eminaga, Fred Saad, Zhe Tian, Ulrich Wolffgang, Pierre I. Karakiewicz, Véronique Ouellet, Feryel Azzi, Tilmann Spieker, Burkhard M. Helmke, Markus Graefen, Xiaoyi Jiang, Lei Xing, Jorn H. Witt, Dominique Trudel, Sami-Ramzi Leyh-Bannurah

“…Abstract Malignancy grading of prostate cancer (PCa) is fundamental for risk stratification, patient counseling, and treatment decision-making. Deep learning…”
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The Impact of Stromal Cell Contamination on Chemosensitivity Testing of Head and Neck Carcinoma by DOLLNER, Ralph, GRANZOW, Christof, HELMKE, Burkhard M, RUESS, Alexandra, SCHAD, Arno, DIETZ, Andreas

“…Background: Reliable chemosensitivity testing of head and neck squamous cell carcinoma (HNSCC) still faces methodical limitations. Since stromal cell…”
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Heparanase expression in head and neck squamous cell carcinomas is associated with reduced proliferation and improved survival by Mogler, Carolin, Herold-Mende, Christel, Dyckhoff, Gerhard, Jenetzky, Ekkehart, Beckhove, Philipp, Helmke, Burkhard M

“…Mogler C, Herold‐Mende C, Dyckhoff G, Jenetzky E, Beckhove P & Helmke B M
(2011) Histopathology 58, 944–952
Heparanase expression in head and neck squamous…”
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Staged heart transplantation and chemotherapy as a treatment option in patients with severe cardiac light-chain amyloidosis by Kristen, Arnt V., Sack, Falk-Udo, Schonland, Stefan O., Hegenbart, Ute, Helmke, Burkhard M., Koch, Achim, Schnabel, Philipp A., Röcken, Christoph, Hardt, Stefan, Remppis, Andrew, Goldschmidt, Hartmut, Karck, Matthias, Ho, Anthony D., Katus, Hugo A., Dengler, Thomas J.

“…Aims The prognosis of advanced cardiac light-chain amyloidosis is poor. Heart transplantation might enable causative therapy and ultimately improve prognosis…”
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