Search Results - "HELLMIG, Stephan"
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Fungi and inflammatory bowel diseases: Alterations of composition and diversity
Published in Scandinavian journal of gastroenterology (2008)“…Objective. Altered bacterial diversity of the intestinal mucosa-associated microbiota may reflect the net influence of lifestyle factors associated with the…”
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Transcriptional activity of the dominant gut mucosal microbiota in chronic inflammatory bowel disease patients
Published in Journal of medical microbiology (01-09-2010)“…Dysbiosis of the gut mucosa-associated microbiota (MAM) plays a pivotal role in the pathogenesis of chronic inflammatory bowel diseases (IBD). To date,…”
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Intestinal TM7 bacterial phylogenies in active inflammatory bowel disease
Published in Journal of medical microbiology (01-12-2008)“…1 Clinic for General Internal Medicine, I. Medical Department, University Hospital Schleswig-Holstein (UKSH), Campus Kiel, Brunswiker Str. 10, D-24105 Kiel,…”
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Regulation of DMBT1 via NOD2 and TLR4 in Intestinal Epithelial Cells Modulates Bacterial Recognition and Invasion
Published in Journal of Immunology (15-06-2007)“…Mucosal epithelial cell layers are constantly exposed to a complex resident microflora. Deleted in malignant brain tumors 1 (DMBT1) belongs to the group of…”
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Effects of probiotics and antibiotics on the intestinal homeostasis in a computer controlled model of the large intestine
Published in BMC microbiology (27-03-2012)“…Antibiotic associated diarrhea and Clostridium difficile infection are frequent complications of broad spectrum antibiotic therapy. Probiotic bacteria are used…”
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Influence of polymorphisms in the NOD1/CARD4 and NOD2/CARD15 genes on the clinical outcome of Helicobacter pylori infection
Published in Cellular microbiology (01-07-2006)“…Summary Host immune response influences the clinical outcome of Helicobacter pylori infection leading to ulcer disease, gastric carcinoma and mucosa‐associated…”
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A Short Isoform of NOD2/CARD15, NOD2-S, Is an Endogenous Inhibitor of NOD2/Receptor-Interacting Protein Kinase 2-Induced Signaling Pathways
Published in Proceedings of the National Academy of Sciences - PNAS (28-02-2006)“…Alterations in splicing patterns of genes contribute to the regulation of gene function by generating endogenous inhibitor or activator molecules…”
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Investigation of the colorectal cancer susceptibility region on chromosome 8q24.21 in a large German case‐control sample
Published in International journal of cancer (01-01-2009)“…Human chromosome 8q24.21 has been implicated as a susceptibility region for colorectal cancer (CRC) as a result of genome‐wide association and candidate gene…”
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Polymorphisms in the 3′-untranslated region of the CDH1 gene are a risk factor for primary gastric diffuse large B-cell lymphoma
Published in Haematologica (Roma) (01-07-2011)“…Primary gastric B-cell lymphomas arise from mucosa-associated lymphatic tissue (MALT) in patients with chronic Helicobacter pylori infection. We investigated…”
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Fungal rDNA signatures in coronary atherosclerotic plaques
Published in Environmental microbiology (01-12-2007)“…Bacterial DNA has been found in coronary plaques and it has therefore been concluded that bacteria may play a role as trigger factors in the chronic…”
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Gastric emptying time of fluids and solids in healthy subjects determined by 13C breath tests: influence of age, sex and body mass index
Published in Journal of gastroenterology and hepatology (01-12-2006)“…Background and Aim: Disturbance of gastric emptying leads to a variety of symptoms. Furthermore, gastric motility disorders might play a role in the…”
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Endoscopic-guided capsule endoscopy in a patient with small-bowel varices after Whipple's operation
Published in Gastrointestinal endoscopy (01-07-2005)Get full text
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13
Influence of ethnic background on genetic susceptibility to H. pylori infection
Published in European journal of gastroenterology & hepatology (01-08-2007)Get full text
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Detection of diverse bacterial signatures in atherosclerotic lesions of patients with coronary heart disease
Published in Circulation (New York, N.Y.) (21-02-2006)“…Bacterial infection has been discussed as a potential etiologic factor in the pathophysiology of coronary heart disease (CHD). This study analyzes molecular…”
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Allelic variation of the matrix metalloproteinase‐9 gene is associated with collagenous colitis
Published in Inflammatory bowel diseases (01-11-2011)“…Background: Collagenous colitis is a chronic inflammatory bowel disease of unknown origin characterized by a thickened subepithelial collagen layer…”
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A Frequent Toll-Like Receptor 1 Gene Polymorphism Affects NK- and T-cell IFN-γ Production and is Associated with Helicobacter pylori-induced Gastric Disease
Published in Helicobacter (Cambridge, Mass.) (01-02-2013)“…Background Helicobacter pylori infects approximately 50% of the world population. Among the infected individuals, only 10–20% develop peptic ulcers and <3%…”
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Germline variations of the MALT1 gene as risk factors in the development of primary gastric B-cell lymphoma
Published in European Journal of Cancer (01-07-2009)“…Abstract Gastric mucosa-associated lymphoid tissue (MALT) lymphoma is a histologically distinct tumour derived from MALT acquired as a result of Helicobacter…”
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Interleukin-10 (-819 C/T) and TNF-A (-308 G/A) as Risk Factors for H. pylori-Associated Gastric MALT-Lymphoma
Published in Digestive diseases and sciences (01-07-2008)Get full text
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Genetic variants in matrix metalloproteinase genes are associated with development of gastric ulcer in H. Pylori infection
Published in The American journal of gastroenterology (2006)“…Matrix metalloproteinases (MMPs) are a family of enzymes that degrade most of the macromolecules making up the extracellular matrix. H. pylori infection…”
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NOD2/CARD15 gene polymorphisms are not associated with collagenous colitis
Published in International journal of colorectal disease (01-04-2007)“…Collagenous colitis is a chronic inflammatory bowel disease of unknown origin. In some cases of collagenous colitis, histomorphological features are comparable…”
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