Search Results - "HELLER, P. G."

Somatic mutations associated with leukemic progression of familial platelet disorder with predisposition to acute myeloid leukemia by Antony-Debré, I, Duployez, N, Bucci, M, Geffroy, S, Micol, J-B, Renneville, A, Boissel, N, Dhédin, N, Réa, D, Nelken, B, Berthon, C, Leblanc, T, Mozziconacci, M-J, Favier, R, Heller, P G, Abdel-Wahab, O, Raslova, H, Latger-Cannard, V, Preudhomme, C

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Primary myelofibrosis in a patient who developed primary biliary cirrhosis, autoimmune hemolytic anemia and fibrillary glomerulonephritis by Kornblihtt, L. I., Vassalllu, P. S., Heller, P. G., Lago, N. R., Alvarez, C. L., Molinas, F. C.

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Mechanisms underlying platelet function defect in a pedigree with familial platelet disorder with a predisposition to acute myelogenous leukemia: potential role for candidate RUNX1 targets by Glembotsky, A. C., Bluteau, D., Espasandin, Y. R., Goette, N. P., Marta, R. F., Marin Oyarzun, C. P., Korin, L., Lev, P. R., Laguens, R. P., Molinas, F. C., Raslova, H., Heller, P. G.

“…Summary Background Familial platelet disorder with a predisposition to acute myelogenous leukemia (FPD/AML) is an inherited platelet disorder caused by a…”
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Anagrelide platelet‐lowering effect is due to inhibition of both megakaryocyte maturation and proplatelet formation: insight into potential mechanisms by Espasandin, Y. R., Glembotsky, A. C., Grodzielski, M., Lev, P. R., Goette, N. P., Molinas, F. C., Marta, R. F., Heller, P. G.

“…Summary Background and Objectives Anagrelide represents a treatment option for essential thrombocythemia patients. It lowers platelet counts through inhibition…”
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International collaboration as a tool for diagnosis of patients with inherited thrombocytopenia in the setting of a developing country by GLEMBOTSKY, A. C., MARTA, R. F., PECCI, A., DE ROCCO, D., GNAN, C., ESPASANDIN, Y. R., GOETTE, N. P., NEGRO, F., NORIS, P., SAVOIA, A., BALDUINI, C. L., MOLINAS, F. C., HELLER, P. G.

“…Background:  Inherited thrombocytopenias (ITs) are heterogeneous genetic disorders that frequently represent a diagnostic challenge. The requirement of highly…”
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Associated thrombophilic defects in essential thrombocythaemia: their relationship with clinical manifestations by Kornblihtt, L.I, Heller, P.G, Correa, G, Castañón, M, Genoud, V, Vassallu, P, Sarano, J, Kordich, L, Molinas, F.C

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Pulmonary hypertension in paroxysmal nocturnal hemoglobinuria by Heller, P G, Grinberg, A R, Lencioni, M, Molina, M M, Roncoroni, A J

“…Pulmonary arterial hypertension (PAH) and cor pulmonale were found in a patient with paroxysmal nocturnal hemoglobinuria (PNH). Autopsy revealed widespread…”
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Monocyte IL-2Rα expression is associated with thrombosis and the JAK2V617F mutation in myeloproliferative neoplasms by Goette, N.P., Lev, P.R., Heller, P.G., Kornblihtt, L.I., Korin, L., Molinas, F.C., Marta, R.F.

“…The development of bone marrow fibrosis and thrombosis are main causes of morbidity in essential thrombocythemia (ET). Monocyte activation has been associated…”
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Production of functional platelet-like particles by the megakaryoblastic DAMI cell line provides a model for platelet biogenesis by Lev, P. R., Goette, N. P., Glembotsky, A. C., Laguens, R. P., Meckert, P. M. Cabeza, Salim, J. P., Heller, P. G., Pozner, R. G., Marta, R. F., Molinas, F. C.

“…The aim of this study was to evaluate cell maturation and the platelet production capacity of the megakaryoblastic DAMI cell line, to characterize…”
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Diverse Mpl expression pattern among pedigrees with inherited thrombocytopenia: potential diagnostic and therapeutic implications by HELLER, P. G., GLEMBOTSKY, A. C., GOETTE, N. P., MARTA, R. F., LEV, P. R., MOLINAS, F. C.

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Analysis of 339 pregnancies in 181 women with 13 different forms of inherited thrombocytopenia by Noris, Patrizia, Schlegel, Nicole, Klersy, Catherine, Heller, Paula G, Civaschi, Elisa, Pujol-Moix, Nuria, Fabris, Fabrizio, Favier, Remi, Gresele, Paolo, Latger-Cannard, Véronique, Cuker, Adam, Nurden, Paquita, Greinacher, Andreas, Cattaneo, Marco, De Candia, Erica, Pecci, Alessandro, Hurtaud-Roux, Marie-Françoise, Glembotsky, Ana C, Muñiz-Diaz, Eduardo, Randi, Maria Luigia, Trillot, Nathalie, Bury, Loredana, Lecompte, Thomas, Marconi, Caterina, Savoia, Anna, Balduini, Carlo L, Bayart, Sophie, Bauters, Anne, Benabdallah-Guedira, Schéhérazade, Boehlen, Françoise, Borg, Jeanne-Yvonne, Bottega, Roberta, Bussel, James, De Rocco, Daniela, de Maistre, Emmanuel, Faleschini, Michela, Falcinelli, Emanuela, Ferrari, Silvia, Ferster, Alina, Fierro, Tiziana, Fleury, Dominique, Fontana, Pierre, James, Chloé, Lanza, Francois, Le Cam Duchez, Véronique, Loffredo, Giuseppe, Magini, Pamela, Martin-Coignard, Dominique, Menard, Fanny, Mercier, Sandra, Mezzasoma, Annamaria, Minuz, Pietro, Nichele, Ilaria, Notarangelo, Lucia D, Pippucci, Tommaso, Podda, Gian Marco, Pouymayou, Catherine, Rigouzzo, Agnes, Royer, Bruno, Sie, Pierre, Siguret, Virginie, Trichet, Catherine, Tucci, Alessandra, Saposnik, Béatrice, Veneri, Dino

“…Pregnancy in women with inherited thrombocytopenias is a major matter of concern as both the mothers and the newborns are potentially at risk of bleeding…”
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Heavy chain myosin 9-related disease (MYH9 -RD): neutrophil inclusions of myosin-9 as a pathognomonic sign of the disorder by Savoia, Anna, De Rocco, Daniela, Panza, Emanuele, Bozzi, Valeria, Scandellari, Raffaella, Loffredo, Giuseppe, Mumford, Andrew, Heller, Paula G, Noris, Patrizia, De Groot, Marco R, Giani, Marisa, Freddi, Paolo, Scognamiglio, Francesca, Riondino, Silvia, Pujol-Moix, Núria, Fabris, Fabrizio, Seri, Marco, Balduini, Carlo L, Pecci, Alessandro

“…MYH9-related disease ( MYH9-RD) is an autosomal dominant thrombocytopenia with giant platelets variably associated with young-adult onset of progressive…”
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Correlation between platelet phenotype and NBEAL2 genotype in patients with congenital thrombocytopenia and  -granule deficiency by Bottega, R., Pecci, A., De Candia, E., Pujol-Moix, N., Heller, P. G., Noris, P., De Rocco, D., Podda, G. M., Glembotsky, A. C., Cattaneo, M., Balduini, C. L., Savoia, A.

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A Deep Dive into the Pathology of Gray Platelet Syndrome: New Insights on Immune Dysregulation by Glembotsky, Ana C, De Luca, Geraldine, Heller, Paula G

“…The gray platelet syndrome (GPS) is a rare platelet disorder, characterized by impaired alpha-granule biogenesis in megakaryocytes and platelets due to NBEAL2…”
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Monocyte IL-2Ralpha expression is associated with thrombosis and the JAK2V617F mutation in myeloproliferative neoplasms by Goette, N P, Lev, P R, Heller, P G, Kornblihtt, L I, Korin, L, Molinas, F C, Marta, R F

“…The development of bone marrow fibrosis and thrombosis are main causes of morbidity in essential thrombocythemia (ET). Monocyte activation has been associated…”
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Low Mpl receptor expression in a pedigree with familial platelet disorder with predisposition to acute myelogenous leukemia and a novel AML1 mutation by Heller, Paula G., Glembotsky, Ana C., Gandhi, Manish J., Cummings, Carrie L., Pirola, Carlos J., Marta, Rosana F., Kornblihtt, Laura I., Drachman, Jonathan G., Molinas, Felisa C.

“…Germ-line heterozygous mutations in the hematopoietic transcription factor AML1 (RUNX1) have been identified in patients with familial platelet disorder with…”
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Moyamoya syndrome in an adolescent with essential thrombocythemia: successful intracranial carotid stent placement by Kornblihtt, Laura I, Cocorullo, Silvia, Miranda, Carlos, Lylyk, Pedro, Heller, Paula G, Molinas, Felisa C

“…Essential thrombocythemia (ET) is a chronic myeloproliferative disorder with increased frequency of thrombotic events, including transient ischemic attacks…”
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The clinical course of patients with septic abortion admitted to an intensive care unit by FINKIELMAN, Javier Daniel, DE FEO, Fabian Dario, HELLER, Paula Graciela, AFESSA, Bekele

“…The purpose of this study was to describe the clinical course, complications, and outcome of patients with septic abortion admitted to the intensive care unit…”
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Catastrophic antiphospholipid syndrome. Communication of 2 forms of presentation by Grinberg, A R, Heller, P G, Correa, G, Sarano, J F, Molinas, F C, Nicastro, M A, Alvarez, C L

“…Antiphospholipid syndrome is characterized by recurrent fetal loss, arterial and venous thromboses, thrombocytopenia and circulating antiphospholipid…”
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PDGF‐A, PDGF‐B, TGFβ, and bFGF mRNA levels in patients with essential thrombocythemia treated with anagrelide by Lev, Paola R., Salim, Juan P., Kornblihtt, Laura I., Pirola, Carlos J., Marta, Rosana F., Heller, Paula G., Molinas, Felisa C.

“…Plasmatic levels of PDGF‐AB, TGFβ1, and bFGF are increased in patients with essential thrombocythemia (ET) while intraplatelet levels are low for PDGF, normal…”
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