Search Results - "HELFRICH, W"

Targeted Radionuclide and Fluorescence Dual-modality Imaging of Cancer: Preclinical Advances and Clinical Translation by Lütje, S., Rijpkema, M., Helfrich, W., Oyen, W. J. G., Boerman, O. C.

“…In oncology, sensitive and reliable detection tumor tissue is crucial to prevent recurrences and to improve surgical outcome. Currently, extensive research is…”
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Near-infrared fluorescence (NIRF) imaging in breast-conserving surgery: Assessing intraoperative techniques in tissue-simulating breast phantoms by Pleijhuis, R.G, Langhout, G.C, Helfrich, W, Themelis, G, Sarantopoulos, A, Crane, L.M.A, Harlaar, N.J, de Jong, J.S, Ntziachristos, V, van Dam, G.M

“…Abstract Purpose Breast-conserving surgery (BCS) results in tumour-positive surgical margins in up to 40% of the patients. Therefore, new imaging techniques…”
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Melanoma-directed activation of apoptosis using a novel bispecific antibody directed against MCSP and Death Receptor 5 by He, Y, Hendriks, D, Van Ginkel, R, Samplonius, D, Bremer, E, Helfrich, W

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Review: On TRAIL for malignant glioma therapy? by Kuijlen, J. M. A., Bremer, E., Mooij, J. J. A., Den Dunnen, W. F. A., Helfrich, W.

“…J. M. A. Kuijlen, E. Bremer, J. J. A. Mooij, W. F. A. den Dunnen and W. Helfrich (2010) Neuropathology and Applied Neurobiology36, 168–182
On TRAIL for…”
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Programmed Death Ligand 1 (PD-L1)-targeted TRAIL combines PD-L1-mediated checkpoint inhibition with TRAIL-mediated apoptosis induction by Hendriks, D, He, Y, Koopmans, I, Wiersma, V, Van Ginkel, R, Samplonius, D, Helfrich, W, Bremer, E

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Nuclear imaging of prostate cancer with gastrin-releasing-peptide-receptor targeted radiopharmaceuticals by Ananias, H J K, de Jong, I J, Dierckx, R A, van de Wiele, C, Helfrich, W, Elsinga, P H

“…Prostate cancer is one of the most common causes of cancer in men. Evaluating the different stages of prostate cancer with conventional imaging techniques…”
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GRPR-selective PET imaging of prostate cancer using [18F]-lanthionine-bombesin analogs by Carlucci, G., Kuipers, A., Ananias, H.J.K., de Paula Faria, D., Dierckx, R.A.J.O., Helfrich, W., Rink, R., Moll, G.N., de Jong, I.J., Elsinga, P.H.

“…•The GRP receptor is overexpressed in several human cancer, including prostate cancer.•Full-length lanthionine-BBN analogs were used as PET agents for GRPR…”
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Targeted elimination of leukemia stem cells; a new therapeutic approach in hemato-oncology by ten Cate, B, de Bruyn, M, Wei, Y, Bremer, E, Helfrich, W

“…Despite recent advances, treatment of leukemia is often not curative. New insights indicate that this may be attributable to a small population of…”
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A novel AML-selective TRAIL fusion protein that is superior to Gemtuzumab Ozogamicin in terms of in vitro selectivity, activity and stability by ten Cate, B, Bremer, E, de Bruyn, M, Bijma, T, Samplonius, D, Schwemmlein, M, Huls, G, Fey, G, Helfrich, W

“…Gemtuzumab ozogamicin (GO, Mylotarg) is a targeted therapeutic agent in which an anti-CD33 antibody is chemically coupled to a highly cytotoxic calicheamicin…”
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Targeted cancer immunotherapy using ligands of the tumor necrosis factor super-family by Bremer, E, de Bruyn, M, Wajant, H, Helfrich, W

“…Antibody-based therapeutic approaches are yielding more and more of the promise they have held since the conception of the 'magic bullet' theory by Paul…”
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The histone deacetylase inhibitor valproic acid potently augments gemtuzumab ozogamicin-induced apoptosis in acute myeloid leukemic cells by TEN CATE, B, SAMPLONIUS, D. F, BIJMA, T, DE LEIJ, L. F. M. H, HELFRICH, W, BREMER, E

“…Gemtuzumab ozogamicin (GO) is a calicheamicin-conjugated antibody directed against CD33, an antigen highly expressed on acute myeloid leukemic (AML) cells…”
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Systemic gene therapy with interleukin-13 attenuates renal ischemia–reperfusion injury by Sandovici, M., Henning, R.H., van Goor, H., Helfrich, W., de Zeeuw, D., Deelman, L.E.

“…Ischemia–reperfusion injury is a leading cause of acute renal failure and a major determinant in the outcome of kidney transplantation. Here we explored…”
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Epidermal Growth Factor-Like Repeats Mediate Lateral and Reciprocal Interactions of Ep-CAM Molecules in Homophilic Adhesions by Balzar, M., Briaire-de Bruijn, I. H., Rees-Bakker, H. A. M., Prins, F. A., Helfrich, W., de Leij, L., Riethmüller, G., Alberti, S., Warnaar, S. O., Fleuren, G. J., Litvinov, S. V.

“…Article Usage Stats Services MCB Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley…”
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Stiffening of fluid membranes and entropy loss of membrane closure : Two effects of thermal undulations by HELFRICH, W

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Adhesion of lipid membranes induced by CrCl3 by Franke, T, Lipowsky, R, Helfrich, W

“…We describe the apparently first reversible unbinding transition of fluid phosphatidylcholine bilayers. It is induced by minute concentrations of CrCl3 in…”
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Developmental exposure to 2,3,7,8-tetrachlorodibenzo-p-dioxin alters DNA methyltransferase (dnmt) expression in zebrafish (Danio rerio) by Aluru, Neelakanteswar, Kuo, Elaine, Helfrich, Lily W., Karchner, Sibel I., Linney, Elwood A., Pais, June E., Franks, Diana G.

“…DNA methylation is one of the most important epigenetic modifications involved in the regulation of gene expression. The DNA methylation reaction is catalyzed…”
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Deployment of regulatory genes during gastrulation and germ layer specification in a model spiralian mollusc Crepidula by Perry, Kimberly J., Lyons, Deirdre C., Truchado‐Garcia, Marta, Fischer, Antje H. L., Helfrich, Lily W., Johansson, Kimberly B., Diamond, Julie C., Grande, Cristina, Henry, Jonathan Q.

“…Background: During gastrulation, endoderm and mesoderm are specified from a bipotential precursor (endomesoderm) that is argued to be homologous across…”
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Measures of integration in the statistical mechanics of polymers and liquid crystals by Helfrich, W

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Effects of a cosurfactant on the stretching and bending elasticities of a surfactant monolayer by Kozlov, M. M, Helfrich, W

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Instability and deformation of a spherical vesicle by pressure by OU-YANG ZHONG-CAN, HELFRICH, W

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