Search Results - "HELFER, E"

Using Real‐World Data to Externally Evaluate Population Pharmacokinetic Models of Dexmedetomidine in Children and Infants by McCann, Sean, Helfer, Victória E., Balevic, Stephen J., Hornik, Chi D., Goldstein, Stuart L., Autmizguine, Julie, Meyer, Marisa, Al‐Uzri, Amira, Anderson, Sarah G., Payne, Elizabeth H., Turdalieva, Sitora, Gonzalez, Daniel

“…Dexmedetomidine is a sedative used in both adults and off‐label in children with considerable reported pharmacokinetic (PK) interindividual variability…”
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Characterizing Enoxaparin’s Population Pharmacokinetics to Guide Dose Individualization in the Pediatric Population by Carreño, Fernando O., Gerhart, Jacqueline G., Helfer, Victória E., Sinha, Jaydeep, Kumar, Karan R., Kirkpatrick, Carl, Hornik, Christoph P., Gonzalez, Daniel

“…Background and Objective Pediatric dosing of enoxaparin was derived based on extrapolation of the adult therapeutic range to children. However, a large…”
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Physiologically‐based pharmacokinetic modeling of pantoprazole to evaluate the role of CYP2C19 genetic variation and obesity in the pediatric population by Thompson, Elizabeth J., Jeong, Angela, Helfer, Victória E., Shakhnovich, Valentina, Edginton, Andrea, Balevic, Stephen J., James, Laura P., Collier, David N., Anand, Ravinder, Gonzalez, Daniel, Benjamin, Daniel K., Kennel, Phyllis, Alderman, Cheryl, Sund, Zoe, Opel, Kylie, Beci, Rose, Hornik, Chi D., Kearns, Gregory L., Paul, Ian M., Sullivan, Janice, Wade, Kelly, Delmore, Paula, Abdel‐Rahman, Susan, Payne, Elizabeth, Chen, Lily, Simone, Gina, O’Connor, Kathleen, Cermak, Jennifer, Taylor, Lawrence, Green, Thomas, Taylor‐Zapata, Perdita, Kearns, Greg, Paul, Ian, Autmizguine, Julie, Capparelli, Edmund, Zimmerman, Kanecia, Greenberg, Rachel, Green, Terren, Livingston, Chad, Bumpass, Tedryl, Howard, Lee, Weigel, Jaylene, Darden‐Saad, Nancy

“…Pantoprazole is a proton pump inhibitor indicated for the treatment of gastroesophageal reflux disease, a condition that disproportionately affects children…”
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Population Pharmacokinetic Modeling as a Tool To Characterize the Decrease in Ciprofloxacin Free Interstitial Levels Caused by Pseudomonas aeruginosa Biofilm Lung Infection in Wistar Rats by Torres, Bruna G S, Helfer, Victória E, Bernardes, Priscila M, Macedo, Alexandre José, Nielsen, Elisabet I, Friberg, Lena E, Dalla Costa, Teresa

“…Biofilm formation plays an important role in the persistence of pulmonary infections, for example, in cystic fibrosis patients. So far, little is known about…”
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Microrheology of biopolymer-membrane complexes by Helfer, E, Harlepp, S, Bourdieu, L, Robert, J, MacKintosh, F C, Chatenay, D

“…We create tailored microstructures, consisting of complexes of lipid membranes with self-assembled biopolymer shells, to study the fundamental properties and…”
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Buckling of actin-coated membranes under application of a local force by Helfer, E, Harlepp, S, Bourdieu, L, Robert, J, MacKintosh, F C, Chatenay, D

“…The mechanical properties of composite membranes obtained by self-assembly of actin filaments with giant fluid vesicles are studied by micromanipulation with…”
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Electrospun scaffolds functionalized with heparin and vascular endothelial growth factor increase the proliferation of endothelial progenitor cells by Braghirolli, D I, Helfer, V E, Chagastelles, P C, Dalberto, T P, Gamba, D, Pranke, P

“…In severe cases of peripheral arterial disease, tissue loss can occur and the use of vascular grafts can be necessary. However, currently, there are no…”
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Viscoelastic properties of actin-coated membranes by Helfer, E, Harlepp, S, Bourdieu, L, Robert, J, MacKintosh, F C, Chatenay, D

“…In living cells, cytoskeletal filaments interact with the plasma membrane to form structures that play a key role in cell shape and mechanical properties. To…”
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A joint numerical and experimental study on the self-organization of red blood cells in confined microfluidic channels by Mendez, S., Iss, C., Midou, D., Moreau, A., Held, D., Charrier, A., Viallat, A., Helfer, E.

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Side-effects of spironolactone therapy in the hirsute woman by Helfer, E L, Miller, J L, Rose, L I

“…Spironolactone, an aldosterone antagonist with antiandrogenic activities, is often used to treat hirsute women. Several investigators have reported beneficial…”
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Child Abuse and Neglect: Assessment, Treatment, and Prevention, October 21, 2007 by Helfer, Ray E

“…Written as though the date were 2007 (20 years after a proposal was made to dismantle protective services for abused children and start anew), this paper…”
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A Biomimetic Motility Assay Provides Insight into the Mechanism of Actin-Based Motility by Wiesner, Sebastian, Helfer, Emmanuele, Didry, Dominique, Ducouret, Guylaine, Lafuma, Françoise, Carlier, Marie-France, Pantaloni, Dominique

“…A biomimetic motility assay is used to analyze the mechanism of force production by site-directed polymerization of actin. Polystyrene microspheres,…”
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Injuries resulting when small children fall out of bed by Helfer, R E, Slovis, T L, Black, M

“…Children frequently fall out of bed but seldom incur serious injury. When such a fall raises parental concern, the pediatrician is consulted; even in this…”
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The perinatal period, a window of opportunity for enhancing parent-infant communication: an approach to prevention by Helfer, R E

“…The perinatal period, broadly defined, encompasses the time frame from one year before to 18 to 24 months after the birth of the child. This period constitutes…”
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Corticosteroids and adrenal suppression: characterising and avoiding the problem by HELFER, E. L, ROSE, L. I

“…Glucocorticoids are used for a variety of illnesses. One of their major complications is suppression of the hypothalamic-pituitary-adrenal axis, rendering a…”
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The neglect of our children by Helfer, R E

“…When we consider all the manifestations of the effects of not meeting the basic needs of our children, we can feel nothing short of alarm and concern. The…”
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A review of the literature on the prevention of child abuse and neglect by Helfer, R E

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Mammalian twinfilin sequesters ADP-G-actin and caps filament barbed ends: implications in motility by Helfer, E, Nevalainen, E.M, Naumanen, P, Romero, S, Didry, D, Pantaloni, D, Lappalainen, P, Carlier, M.F

“…Twinfilins are conserved actin‐binding proteins composed of two actin depolymerizing factor homology (ADF‐H) domains. Twinfilins are involved in diverse…”
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Where to now, Henry? A commentary on the battered child syndrome by Helfer, R E

“…On March 30, 1984, I was given the privilege of delivering the introductory speech at the first American Medical Association (AMA) meeting exclusively for…”
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Cost effectiveness of routine gonadotropin and androgen measurements in hirsute women by Helfer, E L, Miller, J L, Rose, L I

“…Many physicians routinely measure the gonadotropins PRL, LH, and FSH and the androgens dehydroepiandrosterone (DHEA), androstenedione (ADIONE), and…”
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