Search Results - "HEITZ, Florian"

Operability and chemotherapy responsiveness in advanced low-grade serous ovarian cancer. An analysis of the AGO Study Group metadatabase by Grabowski, Jacek P, Harter, Philipp, Heitz, Florian, Pujade-Lauraine, Eric, Reuss, Alexander, Kristensen, Gunnar, Ray-Coquard, Isabelle, Heitz, Julia, Traut, Alexander, Pfisterer, Jacobus, du Bois, Andreas

“…Abstract Objective Since almost two decades standard 1st-line chemotherapy for advanced ovarian cancer (AOC) has been a platinum/taxane combination. More…”
Get full text

Prevalence of deleterious germline variants in risk genes including BRCA1/2 in consecutive ovarian cancer patients (AGO-TR-1) by Harter, Philipp, Hauke, Jan, Heitz, Florian, Reuss, Alexander, Kommoss, Stefan, Marmé, Frederik, Heimbach, André, Prieske, Katharina, Richters, Lisa, Burges, Alexander, Neidhardt, Guido, de Gregorio, Nikolaus, El-Balat, Ahmed, Hilpert, Felix, Meier, Werner, Kimmig, Rainer, Kast, Karin, Sehouli, Jalid, Baumann, Klaus, Jackisch, Christian, Park-Simon, Tjoung-Won, Hanker, Lars, Kröber, Sandra, Pfisterer, Jacobus, Gevensleben, Heidrun, Schnelzer, Andreas, Dietrich, Dimo, Neunhöffer, Tanja, Krockenberger, Mathias, Brucker, Sara Y, Nürnberg, Peter, Thiele, Holger, Altmüller, Janine, Lamla, Josefin, Elser, Gabriele, du Bois, Andreas, Hahnen, Eric, Schmutzler, Rita

“…Identification of families at risk for ovarian cancer offers the opportunity to consider prophylactic surgery thus reducing ovarian cancer mortality. So far,…”
Get full text

Lavage of the Uterine Cavity for Molecular Detection of Müllerian Duct Carcinomas: A Proof-of-Concept Study by Maritschnegg, Elisabeth, Wang, Yuxuan, Pecha, Nina, Horvat, Reinhard, Van Nieuwenhuysen, Els, Vergote, Ignace, Heitz, Florian, Sehouli, Jalid, Kinde, Isaac, Diaz, Jr, Luis A, Papadopoulos, Nickolas, Kinzler, Kenneth W, Vogelstein, Bert, Speiser, Paul, Zeillinger, Robert

“…Type II ovarian cancer (OC) and endometrial cancer (EC) are generally diagnosed at an advanced stage, translating into a poor survival rate. There is…”
Get full text

Endometrial Cancer Molecular Risk Stratification is Equally Prognostic for Endometrioid Ovarian Carcinoma by Krämer, Pauline, Talhouk, Aline, Brett, Mary Anne, Chiu, Derek S, Cairns, Evan S, Scheunhage, Daniëlla A, Hammond, Rory F L, Farnell, David, Nazeran, Tayyebeh M, Grube, Marcel, Xia, Zhouchunyang, Senz, Janine, Leung, Samuel, Feil, Lukas, Pasternak, Jana, Dixon, Katherine, Hartkopf, Andreas, Krämer, Bernhard, Brucker, Sara, Heitz, Florian, du Bois, Andreas, Harter, Philipp, Kommoss, Felix K F, Sinn, Hans-Peter, Heublein, Sabine, Kommoss, Friedrich, Vollert, Hans-Walter, Manchanda, Ranjit, de Kroon, Cornelis D, Nijman, Hans W, de Bruyn, Marco, Thompson, Emily F, Bashashati, Ali, McAlpine, Jessica N, Singh, Naveena, Tinker, Anna V, Staebler, Annette, Bosse, Tjalling, Kommoss, Stefan, Köbel, Martin, Anglesio, Michael S

“…Endometrioid ovarian carcinoma (ENOC) is generally associated with a more favorable prognosis compared with other ovarian carcinomas. Nonetheless, current…”
Get full text

Incidence patterns and temporal trends of invasive nonmelanotic vulvar tumors in Germany 1999-2011. A population-based cancer registry analysis by Buttmann-Schweiger, Nina, Klug, Stefanie J, Luyten, Alexander, Holleczek, Bernd, Heitz, Florian, du Bois, Andreas, Kraywinkel, Klaus

“…Time trends on the incidence and characteristics of invasive vulvar cancer in Germany have so far been studied in few local population- and hospital based…”
Get full text

Validation analysis of the novel imaging-based prognostic radiomic signature in patients undergoing primary surgery for advanced high-grade serous ovarian cancer (HGSOC) by Fotopoulou, Christina, Rockall, Andrea, Lu, Haonan, Lee, Philippa, Avesani, Giacomo, Russo, Luca, Petta, Federica, Ataseven, Beyhan, Waltering, Kai-Uwe, Koch, Jens Albrecht, Crum, William R., Cunnea, Paula, Heitz, Florian, Harter, Philipp, Aboagye, Eric O., du Bois, Andreas, Prader, Sonia

“…Background Predictive models based on radiomics features are novel, highly promising approaches for gynaecological oncology. Here, we wish to assess the…”
Get full text

Pattern and impact of metastatic cardiophrenic lymph nodes in advanced epithelial ovarian cancer by Prader, Sonia, Vollmar, Nils, du Bois, Andreas, Heitz, Florian, Schneider, Stephanie, Ataseven, Beyhan, Bommert, Mareike, Waltering, Kai-Uwe, Heikaus, Sebastian, Koch, Jens Albrecht, Alesina, Pier Francesco, Traut, Alexander, Harter, Philipp

“…Cardiophrenic lymph nodes (CPLN) define FIGO stage IVB disease. We evaluate the pattern of CPLN metastases, their prognostic impact and the potential role of…”
Get full text

Triple-negative and HER2-overexpressing breast cancers exhibit an elevated risk and an earlier occurrence of cerebral metastases by Heitz, Florian, Harter, Philipp, Lueck, Hans-Joachim, Fissler-Eckhoff, Annette, Lorenz-Salehi, Fatemeh, Scheil-Bertram, Stefanie, Traut, Alexander, Bois, Andreas du

“…Abstract Purpose Evaluation of the influence of immunohistochemically defined breast cancer (BC) subtypes and other risk factors on the development of cerebral…”
Get full text

Re-treatment with PARPi in patients with recurrent epithelial ovarian cancer: A single institutional experience by Moubarak, Malak, Harter, Philipp, Ataseven, Beyhan, Traut, Alexander, Welz, Julia, Baert, Thais, Heitz, Florian

“…•Real-life data support prospective evidence that 2nd PARPi therapy can be beneficial.•Patients who do not meet OREO criteria might also benefit from a PARPi…”
Get full text

Perception of side effects associated with anticancer treatment in women with breast or ovarian cancer (KEM-GO-1): a prospective trial by Ataseven, Beyhan, Frindte, Johanna, Harter, Philipp, Gebers, Gudrun, Vogt, Caroline, Traut, Alexander, Breit, Elisabeth, Bluni, Vincenzo, Reinisch, Mattea, Heitz, Florian, Kostara, Athina, Kuemmel, Sherko, Prader, Sonia, Bommert, Mareike, Schneider, Stephanie, du Bois, Andreas

“…Purpose Due to advances in anticancer treatment and supportive care, patients increasingly complained about nonphysical side effects of chemotherapy and…”
Get full text

Cell-free tumor DNA, CA125 and HE4 for the objective assessment of tumor burden in patients with advanced high-grade serous ovarian cancer by Heitz, Florian, Lakis, Sotirios, Harter, Philipp, Heikaus, Sebastian, Sehouli, Jalid, Talwar, Jatin, Menon, Roopika, Ataseven, Beyhan, Bertrand, Miriam, Schneider, Stephanie, Mariotti, Erika, Bommert, Mareike, Müller, Judith N, Prader, Sonia, Leenders, Frauke, Hengsbach, Alexandra, Gloeckner, Christian, Braicu, Elena Ioana, Heukamp, Lukas C, du Bois, Andreas, Heuckmann, Johannes M

“…The present prospective study aimed at determining the impact of cell-free tumor DNA (ct-DNA), CA125 and HE4 from blood and ascites for quantification of tumor…”
Get full text

Sentinel lymph node mapping with fluorescent and radioactive tracers in vulvar cancer patients by Prader, Sonia, du Bois, Andreas, Harter, Philipp, Breit, Elisabeth, Schneider, Stephanie, Baert, Thais, Heitz, Florian, Traut, Alexander, Ehmann, Sarah, Pauly, Nina, Heikaus, Sebastian, Moka, Detlef, Ataseven, Beyhan

“…Purpose Application of radioactive tracers for sentinel lymph node biopsy (SLNB) in vulvar cancer has been established, however, the use of radioisotopes is…”
Get full text

Prognostic Impact of Port-Site Metastasis After Diagnostic Laparoscopy for Epithelial Ovarian Cancer by Ataseven, Beyhan, Grimm, Christoph, Harter, Philipp, Heikaus, Sebastian, Heitz, Florian, Traut, Alexander, Prader, Sonia, Kahl, Annett, Schneider, Stefanie, Kurzeder, Christian, du Bois, Andreas

“…Background This study was designed to evaluate the prevalence, morbidity, and prognostic impact of port-site metastasis (PSM) in patients with epithelial…”
Get full text

Response evaluation after neoadjuvant therapy: evaluation of chemotherapy response score and serological and/or radiological assessment of response in ovarian cancer patients by Ramspott, Jan Philipp, Baert, Thaïs, MacKintosh, Michelle Louise, Traut, Alexander, Ataseven, Beyhan, Bommert, Mareike, Heitz, Florian, Plett, Helmut, Schneider, Stephanie, Waltering, Kai-Uwe, Heikaus, Sebastian, Harter, Philipp, du Bois, Andreas

“…Purpose The chemotherapy response score (CRS) is a histopathological tool to evaluate response to neoadjuvant chemotherapy (NACT) in high-grade serous ovarian…”
Get full text

Modern day screening for Lynch syndrome in endometrial cancer: the KEM experience by Pauly, Nina, Baert, Thaïs, Schmutzler, Rita, du Bois, Andreas, Schneider, Stephanie, Rhiem, Kerstin, Schömig-Markiefka, Birgid, Siemanowski, Janna, Heikaus, Sebastian, Traut, Alexander, Heitz, Florian, Prader, Sonia, Ehmann, Sarah, Harter, Philipp, Ataseven, Beyhan

“…Purpose Current guidelines for Lynch syndrome detection in endometrial cancer (EC) patients rely either on risk evaluation, based on personal/family history,…”
Get full text

Low-grade Serous Tumors: Are We Making Progress? by Pauly, Nina, Ehmann, Sarah, Ricciardi, Enzo, Ataseven, Beyhan, Bommert, Mareike, Heitz, Florian, Prader, Sonia, Schneider, Stephanie, du Bois, Andreas, Harter, Philipp, Baert, Thaïs

“…Purpose of Review This review provides an overview of the current clinical standard in low-grade serous ovarian cancer (LGSOC). The available evidence for…”
Get full text

The effect of fertility-sparing surgery on sexuality and global quality of life in women with malignant ovarian germ cell and sex cord stromal tumors: an analysis of the CORSETT database of the AGO study group by Hasenburg, Annette, Plett, Hellmut, Krämer, Bernhard, Braicu, Elena, Czogalla, Bastian, Bossart, Michaela, Singer, Susanne, Mayr, Doris, Staebler, Annette, du Bois, Andreas, Kommoss, Stefan, Link, Theresa, Burges, Alexander, Heitz, Florian, Keul, Jacqueline, Trillsch, Fabian, Harter, Philipp, Wimberger, Pauline, Buderath, Paul, Klar, Maximilian

“…Purpose Malignant ovarian germ cell (MOGCT) and sex cord stromal tumors (SCST) are ovarian neoplasms that affect disproportionally young women. Little is known…”
Get full text

Cell-type-specific enrichment of risk-associated regulatory elements at ovarian cancer susceptibility loci by Coetzee, Simon G, Shen, Howard C, Hazelett, Dennis J, Lawrenson, Kate, Kuchenbaecker, Karoline, Tyrer, Jonathan, Rhie, Suhn K, Levanon, Keren, Karst, Alison, Drapkin, Ronny, Ramus, Susan J, Couch, Fergus J, Offit, Kenneth, Chenevix-Trench, Georgia, Monteiro, Alvaro N A, Antoniou, Antonis, Freedman, Matthew, Coetzee, Gerhard A, Pharoah, Paul D P, Noushmehr, Houtan, Gayther, Simon A

“…Understanding the regulatory landscape of the human genome is a central question in complex trait genetics. Most single-nucleotide polymorphisms (SNPs)…”
Get full text

Prognostic and predictive value of the Arbeitsgemeinschaft Gynaekologische Onkologie (AGO) score in surgery for recurrent ovarian cancer by Harter, Philipp, Beutel, Bianca, Alesina, Piero F, Lorenz, Dietmar, Boergers, Andre, Heitz, Florian, Hils, Rita, Kurzeder, Christian, Traut, Alexander, du Bois, Andreas

“…Abstract Objectives The Arbeitsgemeinschaft Gynaekologische Onkologie (AGO) score was developed as selection criteria and validated as predictor of a high…”
Get full text

Synchronous ovarian and endometrial cancer--an international multicenter case-control study by Heitz, Florian, Amant, Frederic, Fotopoulou, Christina, Battista, Marco J, Wimberger, Pauline, Traut, Alexander, Fisseler-Eckhoff, Annette, Harter, Philipp, Vandenput, Ingrid, Sehouli, Jalid, Schmidt, Marcus, Kimmig, Rainer, du Bois, Rabea, du Bois, Andreas

“…This study aimed to compare the prognosis of patients with synchronous endometrial and ovarian cancer (SEOC) to matched controls with either endometrial cancer…”
Get more information