Search Results - "HEISE, Carla C"

Single-agent lenalidomide in relapsed/refractory mantle cell lymphoma: results from a UK phase II study suggest activity and possible gender differences by Eve, Heather E., Carey, Sean, Richardson, Sarah J., Heise, Carla C., Mamidipudi, Vidya, Shi, Tao, Radford, John A., Auer, Rebecca L., Bullard, Sheila H., Rule, Simon A. J.

“…Summary We present data from a phase II study investigating a novel treatment strategy for relapsed/refractory mantle cell lymphoma (MCL). Twenty‐six patients…”
Get full text

CHIR-258 Is Efficacious in A Newly Developed Fibroblast Growth Factor Receptor 3–Expressing Orthotopic Multiple Myeloma Model in Mice by XIAOHUA XIN, ABRAMS, Tinya J, TRUDEL, Suzanne, JALLAL, Bahija, MENDEL, Dirk B, HEISE, Carla C, HOLLENBACH, Paul W, RENDAHL, Katherine G, YAN TANG, OEI, Yoko A, EMBRY, Millicent G, SWINARSKI, Debbie E, GARRETT, Evelyn N, PRYER, Nancy K

“…Purpose: The ectopically expressed and deregulated fibroblast growth factor receptor 3 (FGFR3) results from a t(4;14) chromosomal translocation that occurs in…”
Get full text

Design, Structure−Activity Relationships and in Vivo Characterization of 4-Amino-3-benzimidazol-2-ylhydroquinolin-2-ones: A Novel Class of Receptor Tyrosine Kinase Inhibitors by Renhowe, Paul A, Pecchi, Sabina, Shafer, Cynthia M, Machajewski, Timothy D, Jazan, Elisa M, Taylor, Clarke, Antonios-McCrea, William, McBride, Christopher M, Frazier, Kelly, Wiesmann, Marion, Lapointe, Gena R, Feucht, Paul H, Warne, Robert L, Heise, Carla C, Menezes, Daniel, Aardalen, Kimberly, Ye, Helen, He, Molly, Le, Vincent, Vora, Jayesh, Jansen, Johanna M, Wernette-Hammond, Mary Ellen, Harris, Alex L

“…The inhibition of key receptor tyrosine kinases (RTKs) that are implicated in tumor vasculature formation and maintenance, as well as tumor progression and…”
Get full text

In vivo antitumor activity of ONYX-015 is influenced by p53 status and is augmented by radiotherapy by ROGULSKI, K. R, FREYTAG, S. O, KANG ZHANG, GILBERT, J. D, PAIELLI, D. L, JAE HO KIM, HEISE, C. C, KIRN, D. H

“…The E1B-deleted, replication-competent ONYX-015 (dl1520) adenovirus was originally described as being able to selectively kill p53-deficient cells due to a…”
Get full text

Intravenous administration of ONYX-015, a selectively replicating adenovirus, induces antitumoral efficacy by HEISE, C. C, WILLIAMS, A. M, XUE, S, PROPST, M, KIRN, D. H

“…Replication-incompetent viral vectors are being developed for the gene therapy of cancer. Although some of these may eventually be proven to have significant…”
Get full text

Efficacy of a replication-competent adenovirus (ONYX-015) following intratumoral injection: intratumoral spread and distribution effects by Heise, C C, Williams, A, Olesch, J, Kirn, D H

“…ONYX-015 is an E1B-deleted adenovirus that replicates in and causes lysis of p53-deficient cancer cells selectively. To study the efficiency of intratumoral…”
Get full text

Differences in viral distribution and cell adhesion molecule expression in the intestinal tract of rhesus macaques infected with pathogenic and nonpathogenic SIV by Stone, J D, Heise, C C, Canfield, D R, Elices, M J, Dandekar, S

“…We investigated SIV infection and expression of adhesion molecules in the small intestine of rhesus macaques infected with pathogenic SIV (SIVmac) or…”
Get more information

Hyperzincuria in IDDM women: relationship to measures of glycemic control, renal function, and tissue catabolism by Heise, C.C, King, J.C, Costa, F.M, Kitzmiller, J.L

“…Eighteen women with insulin-dependent diabetes mellitus (IDDM) and 15 nondiabetic women participated in a study of the relationship of zincuria to measures of…”
Get full text

Development of malabsorption and nutritional complications in simian immunodeficiency virus-infected rhesus macaques by Stone, J D, Heise, C C, Miller, C J, Halsted, C H, Dandekar, S

“…To assess the development and cause of malabsorption in rhesus macaques following experimental simian immunodeficiency virus (SIV) infection and to evaluate…”
Get more information