Search Results - "HEINZ, Franz X"

Distinguishing features of current COVID-19 vaccines: knowns and unknowns of antigen presentation and modes of action by Heinz, Franz X., Stiasny, Karin

“…COVID-19 vaccines were developed with an unprecedented pace since the beginning of the pandemic. Several of them have reached market authorization and mass…”
Get full text

The Antigenic Structure of Zika Virus and Its Relation to Other Flaviviruses: Implications for Infection and Immunoprophylaxis by Heinz, Franz X, Stiasny, Karin

“…Zika virus was discovered ∼70 years ago in Uganda and maintained a low profile as a human disease agent in Africa and Asia. Only recently has it caused…”
Get full text

The bright and the dark side of human antibody responses to flaviviruses: lessons for vaccine design by Rey, Félix A, Stiasny, Karin, Vaney, Marie‐Christine, Dellarole, Mariano, Heinz, Franz X

“…Zika and dengue viruses belong to the Flavivirus genus, a close group of antigenically related viruses that cause significant arthropod‐transmitted diseases…”
Get full text

Structural basis of potent Zika–dengue virus antibody cross-neutralization by Barba-Spaeth, Giovanna, Dejnirattisai, Wanwisa, Rouvinski, Alexander, Vaney, Marie-Christine, Medits, Iris, Sharma, Arvind, Simon-Lorière, Etienne, Sakuntabhai, Anavaj, Cao-Lormeau, Van-Mai, Haouz, Ahmed, England, Patrick, Stiasny, Karin, Mongkolsapaya, Juthathip, Heinz, Franz X., Screaton, Gavin R., Rey, Félix A.

“…Zika virus is a member of the Flavivirus genus that had not been associated with severe disease in humans until the recent outbreaks, when it was linked to…”
Get full text

A novel mechanism of antibody-mediated enhancement of flavivirus infection by Haslwanter, Denise, Blaas, Dieter, Heinz, Franz X, Stiasny, Karin

“…Antibody-dependent enhancement of viral infection is a well-described phenomenon that is based on the cellular uptake of infectious virus-antibody complexes…”
Get full text

Vaccination and tick-borne encephalitis, central Europe by Heinz, Franz X, Stiasny, Karin, Holzmann, Heidemarie, Grgic-Vitek, Marta, Kriz, Bohumir, Essl, Astrid, Kundi, Michael

“…Tick-borne encephalitis (TBE) is a substantial public health problem in many parts of Europe and Asia. To assess the effect of increasing TBE vaccination…”
Get full text

Identification of specific histidines as pH sensors in flavivirus membrane fusion by Fritz, Richard, Stiasny, Karin, Heinz, Franz X

“…The flavivirus membrane fusion machinery, like that of many other enveloped viruses, is triggered by the acidic pH in endosomes after virus uptake by…”
Get full text

Evolution and activation mechanism of the flavivirus class II membrane-fusion machinery by Vaney, Marie-Christine, Dellarole, Mariano, Duquerroy, Stéphane, Medits, Iris, Tsouchnikas, Georgios, Rouvinski, Alexander, England, Patrick, Stiasny, Karin, Heinz, Franz X., Rey, Félix A.

“…The flavivirus envelope glycoproteins prM and E drive the assembly of icosahedral, spiky immature particles that bud across the membrane of the endoplasmic…”
Get full text

Field effectiveness of vaccination against tick-borne encephalitis by Heinz, Franz X, Holzmann, Heidemarie, Essl, Astrid, Kundi, Michael

“…Abstract Tick-borne encephalitis (TBE) is a vaccine-preventable disease caused by a flavivirus (TBE virus) that is endemic in many European countries and large…”
Get full text

Flavivirus membrane fusion by Stiasny, Karin, Heinz, Franz X

“…Institute of Virology, Medical University of Vienna, Kinderspitalgasse 15, A1095 Vienna, Austria Correspondence Franz X. Heinz…”
Get full text

Dynamics and Extent of Non-Structural Protein 1-Antibody Responses in Tick-Borne Encephalitis Vaccination Breakthroughs and Unvaccinated Patients by Stiasny, Karin, Leitner, Agnes, Holzmann, Heidemarie, Heinz, Franz X.

“…Tick-borne encephalitis (TBE) has a substantial impact on human public health in many parts of Europe and Asia. Effective inactivated purified whole-virus…”
Get full text

An Absolutely Conserved Tryptophan in the Stem of the Envelope Protein E of Flaviviruses Is Essential for the Formation of Stable Particles by Medits, Iris, Heinz, Franz X, Stiasny, Karin

“…The major envelope protein E of flaviviruses contains an ectodomain that is connected to the transmembrane domain by the so-called "stem" region. In mature…”
Get full text

Cryptic Properties of a Cluster of Dominant Flavivirus Cross-Reactive Antigenic Sites by STIASNY, Karin, KIERMAYR, Stefan, HOLZMANN, Heidemarie, HEINZ, Franz X

“…Article Usage Stats Services JVI Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley…”
Get full text

Influenza A and B Viruses but Not MERS-CoV in Hajj Pilgrims, Austria, 2014 by Aberle, Judith H, Popow-Kraupp, Theresia, Kreidl, Peter, Laferl, Hermann, Heinz, Franz X, Aberle, Stephan W

Get full text

Tick-borne encephalitis from eating goat cheese in a mountain region of Austria by Holzmann, Heidemarie, Aberle, Stephan W, Stiasny, Karin, Werner, Philipp, Mischak, Andreas, Zainer, Bernhard, Netzer, Markus, Koppi, Stefan, Bechter, Elmar, Heinz, Franz X

“…We report transmission of tick-borne encephalitis virus (TBEV) in July 2008 through nonpasteurized goat milk to 6 humans and 4 domestic pigs in an alpine…”
Get full text

Age affects quantity but not quality of antibody responses after vaccination with an inactivated flavivirus vaccine against tick-borne encephalitis by Stiasny, Karin, Aberle, Judith H, Keller, Michael, Grubeck-Loebenstein, Beatrix, Heinz, Franz X

“…The impairment of immune functions in the elderly (immunosenescence) results in post-vaccination antibody titers that are significantly lower than in young…”
Get full text

Impact of flavivirus vaccine-induced immunity on primary Zika virus antibody response in humans by Malafa, Stefan, Medits, Iris, Aberle, Judith H, Aberle, Stephan W, Haslwanter, Denise, Tsouchnikas, Georgios, Wölfel, Silke, Huber, Kristina L, Percivalle, Elena, Cherpillod, Pascal, Thaler, Melissa, Roßbacher, Lena, Kundi, Michael, Heinz, Franz X, Stiasny, Karin

“…Zika virus has recently spread to South- and Central America, causing congenital birth defects and neurological complications. Many people at risk are…”
Get full text

Immunodominance and Functional Activities of Antibody Responses to Inactivated West Nile Virus and Recombinant Subunit Vaccines in Mice by ZLATKOVIC, Juergen, STIASNY, Karin, HEINZ, Franz X

“…Article Usage Stats Services JVI Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley…”
Get full text

Dissection of antibody specificities induced by yellow fever vaccination by Vratskikh, Oksana, Stiasny, Karin, Zlatkovic, Jürgen, Tsouchnikas, Georgios, Jarmer, Johanna, Karrer, Urs, Roggendorf, Michael, Roggendorf, Hedwig, Allwinn, Regina, Heinz, Franz X

“…The live attenuated yellow fever (YF) vaccine has an excellent record of efficacy and one dose provides long-lasting immunity, which in many cases may last a…”
Get full text

Human CD4+ T Helper Cell Responses after Tick-Borne Encephalitis Vaccination and Infection by Aberle, Judith H, Schwaiger, Julia, Aberle, Stephan W, Stiasny, Karin, Scheinost, Ondrej, Kundi, Michael, Chmelik, Vaclav, Heinz, Franz X

“…Tick-borne encephalitis virus (TBEV) is a human-pathogenic flavivirus that is endemic in large parts of Europe and Asia and causes severe neuroinvasive…”
Get full text