Search Results - "HEINE, Robert J"

Translating the A1C Assay Into Estimated Average Glucose Values by Nathan, David M, Kuenen, Judith, Borg, Rikke, Zheng, Hui, Schoenfeld, David, Heine, Robert J

“…OBJECTIVE:--The A1C assay, expressed as the percent of hemoglobin that is glycated, measures chronic glycemia and is widely used to judge the adequacy of…”
Get full text

Survival as a function of HbA1c in people with type 2 diabetes: a retrospective cohort study by Currie, Craig J, Dr, Peters, John R, FRCP, Tynan, Aodán, MSc, Evans, Marc, MD, Heine, Robert J, Prof, Bracco, Oswaldo L, MD, Zagar, Tony, PhD, Poole, Chris D, PhD

“…Summary Background Results of intervention studies in patients with type 2 diabetes have led to concerns about the safety of aiming for normal blood glucose…”
Get full text

Alanine aminotransferase predicts coronary heart disease events: A 10-year follow-up of the Hoorn Study by Schindhelm, Roger K, Dekker, Jacqueline M, Nijpels, Giel, Bouter, Lex M, Stehouwer, Coen D.A, Heine, Robert J, Diamant, Michaela

“…Abstract Alanine aminotransferase (ALT) is a marker of non-alcoholic fatty liver disease (NAFLD) and predicts incident type 2 diabetes mellitus (DM2)…”
Get full text

Pancreatic Fat Content and β-Cell Function in Men With and Without Type 2 Diabetes by Tushuizen, Maarten E, Bunck, Mathijs C, Pouwels, Petra J, Bontemps, Saskia, van Waesberghe, Jan Hein T, Schindhelm, Roger K, Mari, Andrea, Heine, Robert J, Diamant, Michaela

“…OBJECTIVE:--Insulin resistance, associated with increased lipolysis, results in a high exposure of nonadipose tissue to lipids. Experimental data indicate that…”
Get full text

Exenatide affects circulating cardiovascular risk biomarkers independently of changes in body composition by Bunck, Mathijs C, Diamant, Michaela, Eliasson, Bjorn, Cornér, Anja, Shaginian, Rimma M, Heine, Robert J, Taskinen, Marja-Riitta, Yki-Järvinen, Hannele, Smith, Ulf

“…To study the effect of exenatide on body composition and circulating cardiovascular risk biomarkers. Metformin-treated patients with type 2 diabetes (N = 69)…”
Get full text

Metabolic syndrome and 10-year cardiovascular disease risk in the hoorn study by DEKKER, Jacqueline M, GIRMAN, Cynthia, RHODES, Thomas, NIJPELS, Giel, STEHOUWER, Coen D. A, BOUTER, Lex M, HEINE, Robert J

“…Different definitions of the metabolic syndrome have been proposed. Their value in a clinical setting to assess cardiovascular disease (CVD) risk is still…”
Get full text

Vitamin D and mortality in older men and women by Pilz, Stefan, Dobnig, Harald, Nijpels, Giel, Heine, Robert J., Stehouwer, Coen D. A., Snijder, Marieke B., Van Dam, Rob M., Dekker, Jacqueline M.

“…Summary Objective  Vitamin D deficiency is common among the elderly and may contribute to cardiovascular disease. The aim of our study was to elucidate whether…”
Get full text

Alanine aminotransferase as a marker of non-alcoholic fatty liver disease in relation to type 2 diabetes mellitus and cardiovascular disease by Schindhelm, Roger K., Diamant, Michaela, Dekker, Jacqueline M., Tushuizen, Maarten E., Teerlink, Tom, Heine, Robert J.

“…For a long time, hepatic steatosis was believed to be a benign condition. Only recently, liver steatosis, also termed non‐alcoholic fatty liver disease…”
Get full text

Primary Prevention of Cardiovascular Disease and Type 2 Diabetes in Patients at Metabolic Risk: An Endocrine Society Clinical Practice Guideline by Rosenzweig, James L., Ferrannini, Ele, Grundy, Scott M., Haffner, Steven M., Heine, Robert J., Horton, Edward S., Kawamori, Ryuzo

“…Objective: The objective was to develop clinical practice guidelines for the primary prevention of cardiovascular disease (CVD) and type 2 diabetes mellitus…”
Get full text

Endothelial Glycocalyx Damage Coincides With Microalbuminuria in Type 1 Diabetes by NIEUWDORP, Max, MOOIJ, Hans L, KASTELEIN, John J. P, STROES, Erik S. G, VINK, Hans, KROON, Jojanneke, ATASEVER, Bektas, SPAAN, Jos A. E, INCE, Can, HOLLEMAN, Frits, DIAMANT, Michaela, HEINE, Robert J, HOEKSTRA, Joost B. L

“…Endothelial Glycocalyx Damage Coincides With Microalbuminuria in Type 1 Diabetes Max Nieuwdorp 1 , Hans L. Mooij 1 , Jojanneke Kroon 1 , Bektas Atasever 2 ,…”
Get full text

Prognostic Value of Adiponectin for Cardiovascular Disease and Mortality by Dekker, Jacqueline M., Funahashi, Tohru, Nijpels, Giel, Pilz, Stefan, Stehouwer, Coen D. A., Snijder, Marieke B., Bouter, Lex M., Matsuzawa, Yuji, Shimomura, Iichiro, Heine, Robert J.

“…Context: Low adiponectin concentrations are associated with the presence of an adverse cardiovascular disease (CVD) risk profile. Objective: We studied the…”
Get full text

Acute and 2-week exposure to prednisolone impair different aspects of β-cell function in healthy men by van Raalte, Daniël H, Nofrate, Valentina, Bunck, Mathijs C, van Iersel, Thijs, Elassaiss Schaap, Jeroen, Nässander, Ulla K, Heine, Robert J, Mari, Andrea, Dokter, Wim H A, Diamant, Michaela

“…ObjectiveGlucocorticoids (GCs), such as prednisolone, are associated with adverse metabolic effects, including glucose intolerance and diabetes. In contrast to…”
Get full text

Does Glucose Variability Influence the Relationship Between Mean Plasma Glucose and HbA1c Levels in Type 1 and Type 2 Diabetic Patients? by KUENEN, Judith C, BORG, Rikke, KUIK, Dirk J, HUI ZHENG, SCHOENFELD, David, DIAMANT, Michaela, NATHAN, David M, HEINE, Robert J

“…The A1C-Derived Average Glucose (ADAG) study demonstrated a linear relationship between HbA(1c) and mean plasma glucose (MPG). As glucose variability (GV) may…”
Get full text

Cognitive and Functional Decline in Patients With Mild Alzheimer Dementia With or Without Comorbid Diabetes by Ascher-Svanum, Haya, PhD, Chen, Yun-Fei, PhD, Hake, Ann, MD, Kahle-Wrobleski, Kristin, PhD, Schuster, Dara, MD, Kendall, David, MD, Heine, Robert J, MD, PhD

“…Abstract Purpose Although diabetes is recognized as a risk factor for the development of cognitive impairment and for accelerated progression to Alzheimer…”
Get full text

Effects of Hepatic Triglyceride Content on Myocardial Metabolism in Type 2 Diabetes by Rijzewijk, Luuk J., MD, Jonker, Jacqueline T., MD, van der Meer, Rutger W., MD, PhD, Lubberink, Mark, PhD, de Jong, Hugo W., PhD, Romijn, Johannes A., MD, PhD, Bax, Jeroen J., MD, PhD, de Roos, Albert, MD, PhD, Heine, Robert J., MD, PhD, Twisk, Jos W., MD, PhD, Windhorst, Albert D., PhD, Lammertsma, Adriaan A., PhD, Smit, Johannes W.A., MD, PhD, Diamant, Michaela, MD, PhD, Lamb, Hildo J., MD, PhD

“…Objectives The purpose of this study was to investigate the relationship between hepatic triglyceride content and both myocardial function and metabolism in…”
Get full text

Gene Variants in the Novel Type 2 Diabetes Loci CDC123/CAMK1D, THADA, ADAMTS9, BCL11A, and MTNR1B Affect Different Aspects of Pancreatic β-Cell Function by Simonis-Bik, Annemarie M, Nijpels, Giel, van Haeften, Timon W, Houwing-Duistermaat, Jeanine J, Boomsma, Dorret I, Reiling, Erwin, van Hove, Els C, Diamant, Michaela, Kramer, Mark H H, Heine, Robert J, Maassen, J Antonie, Slagboom, P Eline, Willemsen, Gonneke, Dekker, Jacqueline M, Eekhoff, Elisabeth M, de Geus, Eco J, 't Hart, Leen M

“…Gene Variants in the Novel Type 2 Diabetes Loci CDC123/CAMK1D , THADA , ADAMTS9 , BCL11A , and MTNR1B Affect Different Aspects of Pancreatic β-Cell Function…”
Get full text

Effect of Moderate Alcohol Consumption on Adiponectin, Tumor Necrosis Factor-α, and Insulin Sensitivity by SIERKSMA, Aafje, PATEL, Hamina, OUCHI, Noriyuki, KIHARA, Shinji, FUNAHASHI, Tohru, HEINE, Robert J, GROBBEE, Diederick E, KLUFT, Cornelis, HENDRIKS, Henk F. J

“…Effect of Moderate Alcohol Consumption on Adiponectin, Tumor Necrosis Factor-α, and Insulin Sensitivity Aafje Sierksma , MSC 1 2 , Hamina Patel , MD 3 ,…”
Get full text

Potentially modifiable determinants of vitamin D status in an older population in the Netherlands: the Hoorn Study by Dam, Rob M. van, Snijder, Marieke B, Dekker, Jacqueline M, Stehouwer, Coen DA, Bouter, Lex M, Heine, Robert J, Lips, Paul

“…BACKGROUND:Inadequate vitamin D status is common in many populations around the world. OBJECTIVE:The aim was to evaluate potentially modifiable determinants of…”
Get full text

Acute effects of decaffeinated coffee and the major coffee components chlorogenic acid and trigonelline on incretin hormones by Olthof, Margreet R, van Dijk, Aimée E, Deacon, Carolyn F, Heine, Robert J, van Dam, Rob M

“…Coffee consumption is associated with a lower risk of type 2 diabetes. We tested the hypothesis that this is mediated by incretin hormones by measuring the…”
Get full text

Hyperglycemia and Oxidative Stress Strengthen the Association Between Myeloperoxidase and Blood Pressure by Van der Zwan, Leonard P, Scheffer, Peter G, Dekker, Jacqueline M, Stehouwer, Coen D.A, Heine, Robert J, Teerlink, Tom

“…Scavenging of the vasodilator nitric oxide by myeloperoxidase activity in the vasculature may contribute to hypertension. Because hydrogen peroxide is a…”
Get full text