Search Results - "HEIKE JUNG"

Should We Compare Laws or Cultures? by Jung, Heike

“…Law and culture are inextricably linked. Hence, a meaningful comparison of laws will have to take into account the cultural background and the context. The…”
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Efficacy and safety of dulaglutide 3.0 and 4.5 mg in patients aged younger than 65 and 65 years or older: Post hoc analysis of the AWARD‐11 trial by Frias, Juan P., Bonora, Enzo, Nevárez Ruiz, Luis, Hsia, Stanley H., Jung, Heike, Raha, Sohini, Cox, David A., Bethel, M. Angelyn, Konig, Manige

“…Aim To evaluate the efficacy and safety of dulaglutide 3.0 and 4.5 mg versus 1.5 mg when used as an add‐on to metformin in subgroups defined by age (<65 and…”
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Growth Hormone Treatment for Short Stature in the USA, Germany and France: 15 Years of Surveillance in the Genetics and Neuroendocrinology of Short-Stature International Study (GeNeSIS) by Pfäffle, Roland, Land, Christof, Schönau, Eckhard, Holterhus, Paul-Martin, Ross, Judith L, Piras de Oliveira, Carolina, Child, Christopher J, Benabbad, Imane, Jia, Nan, Jung, Heike, Blum, Werner F

“…To describe characteristics, auxological outcomes and safety in paediatric patients with growth disorders treated with growth hormone (GH), for cohorts from…”
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Assessment of primary cancers in GH-treated adult hypopituitary patients: an analysis from the Hypopituitary Control and Complications Study by Child, Christopher J, Zimmermann, Alan G, Woodmansee, Whitney W, Green, Daniel M, Li, Jian J, Jung, Heike, Erfurth, Eva Marie, Robison, Leslie L

“…ObjectiveGH and IGFs have mitogenic properties, causing speculation that GH treatment could increase risk of malignancy. While studies in GH-treated childhood…”
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Enhanced at puberty 1 (EAP1) is a new transcriptional regulator of the female neuroendocrine reproductive axis by Heger, Sabine, Mastronardi, Claudio, Dissen, Gregory A, Lomniczi, Alejandro, Cabrera, Ricardo, Roth, Christian L, Jung, Heike, Galimi, Francesco, Sippell, Wolfgang, Ojeda, Sergio R

“…The initiation of mammalian puberty and the maintenance of female reproductive cycles are events controlled by hypothalamic neurons that secrete the…”
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Expression of a Tumor-Related Gene Network Increases in the Mammalian Hypothalamus at the Time of Female Puberty by Roth, Christian L, Mastronardi, Claudio, Lomniczi, Alejandro, Wright, Hollis, Cabrera, Ricardo, Mungenast, Alison E, Heger, Sabine, Jung, Heike, Dubay, Christopher, Ojeda, Sergio R

“…Much has been learned in recent years about the central mechanisms controlling the initiation of mammalian puberty. It is now clear that this process requires…”
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Changing Patterns of the Adult Growth Hormone Deficiency Diagnosis Documented in a Decade-Long Global Surveillance Database by Webb, Susan M., Strasburger, Christian J., Mo, Daojun, Hartman, Mark L., Melmed, Shlomo, Jung, Heike, Blum, Werner F., Attanasio, Andrea F.

“…Background: GH therapy in adult patients with GH deficiency (GHD) was approved over 10 yr ago, and the indication has subsequently gained broad acceptance. The…”
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Bond strength of a new universal self-adhesive resin luting cement to dentin and enamel by Abo-Hamar, Sahar E, Hiller, Karl-Anton, Jung, Heike, Federlin, Marianne, Friedl, Karl-Heinz, Schmalz, Gottfried

“…The objective of this study was to assess the bonding performance of a new universal self-adhesive cement RelyX Unicem (RXU) to dentin and enamel compared to…”
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Reinforcement of Conducting Silver-based Materials by JUNG, Heike, NESTLER, Daisy, WIELAGE, Bernhard, LAMPKE, Thomas

“…Silver is a well-known material in the field of contact materials because of its high electrical and thermal conductivity. However, due to its bad mechanical…”
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DNA methylation of the p66Shc promoter is decreased in placental tissue from women delivering intrauterine growth restricted neonates by Tzschoppe, Anja, Doerr, Helmuth, Rascher, Wolfgang, Goecke, Tamme, Beckmann, Matthias, Schild, Ralf, Struwe, Ellen, Geisel, Jürgen, Jung, Heike, Dötsch, Jörg

“…ABSTRACT Objective The adaptor protein p66Shc generates mitochondrial reactive oxygen species and translates oxidative signals into apoptosis. We aimed to…”
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Early onset of puberty: tracking genetic and environmental factors by Parent, Anne-Simone, Rasier, Gregory, Gerard, Arlette, Heger, Sabine, Roth, Christian, Mastronardi, Claudio, Jung, Heike, Ojeda, Sergio R, Bourguignon, Jean-Pierre

“…Under physiological conditions, factors affecting the genetic control of hypothalamic functions are predominant in determining the individual variations in…”
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Growth hormone treatment for short stature in children born small for gestational age by Jung, Heike, Rosilio, Myriam, Blum, Werner F., Drop, Stenvert L. S.

“…Children born small for gestational age (SGA) who do not show catch-up in the first 2 years generally remain short for life. Although the majority of children…”
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Pathogenesis of precocious puberty in hypothalamic hamartoma by Jung, Heike, Ojeda, Sergio R

“…Astroglial-derived factors, as transforming growth factor (TGF)alpha and TGFbeta, act in the hypothalamus to activate luteinizing hormone-releasing hormone…”
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Gamma-aminobutyric acid (GABA): a para- and/or autocrine hormone in the pituitary by Mayerhofer, A, Höhne-Zell, B, Gamel-Didelon, K, Jung, H, Redecker, P, Grube, D, Urbanski, H F, Gasnier, B, Fritschy, J M, Gratzl, M

“…The neurotransmitter gamma-aminobutyric acid (GABA) plays an important role in the regulation of pituitary gland function, but details of the underlying…”
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Weight loss in patients with type 2 diabetes receiving once‐weekly dulaglutide plus insulin lispro or insulin glargine plus insulin lispro: A post‐hoc analysis of the AWARD‐4 study across baseline body mass index subgroups by Fuechtenbusch, Martin, Aberle, Jens, Heitmann, Elke, Nicolay, Claudia, Jung, Heike

“…Aims Insulin‐treated patients with type 2 diabetes (T2D) and obesity are challenged in achieving body weight stability or reduction, in addition to glycaemic…”
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Clinical characteristics, treatment patterns, and persistence in individuals with type 2 diabetes initiating a glucagon‐like peptide‐1 receptor agonist: A retrospective analysis of the Diabetes Prospective Follow‐Up Registry by Jung, Heike, Tittel, Sascha R., Schloot, Nanette C., Heitmann, Elke, Otto, Thorsten, Lebrec, Jeremie, Pavel, Marianne, Lanzinger, Stefanie

“…Aims To describe clinical characteristics, treatment patterns and glucagon‐like peptide‐1 receptor agonist (GLP‐1 RA) persistence in individuals with type 2…”
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Utilization patterns of glucagon-like peptide-1 receptor agonists in patients with type 2 diabetes mellitus in Germany: a retrospective cohort study by Otto, Thorsten, Myland, Melissa, Jung, Heike, Lebrec, Jeremie, Richter, Hartmut, Norrbacka, Kirsi

“…Objective: This retrospective database analysis complements previous research to understand treatment patterns for German patients newly-initiating or…”
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Practical Applications of a Nausea and Vomiting Model in the Clinical Development of Additional Doses of Dulaglutide by Tang, Cheng Cai, Lim, Jean, Loo, Li Shen, Jung, Heike, Konig, Manige, Tham, Lai San

“…Dulaglutide 3.0 and 4.5 mg weekly doses were approved for additional glycemic control in adult patients with type 2 diabetes inadequately controlled with…”
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642-P: A Model-Based Evaluation of Nausea and Vomiting Events for Additional Doses of Dulaglutide in Existing and Dulaglutide-Naïve Patients with Type 2 Diabetes by THAM, LAI-SAN, LIM, JEAN S.K., TANG, CHENG CAI, JUNG, HEIKE, KONIG, MANIGE, LOO, LI SHEN

“…Dulaglutide (DU) 3 mg and 4.5 mg once weekly (QW) doses were recently approved for additional glycemic control in adult patients with type 2 diabetes. If…”
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680-P: Once-Weekly Dulaglutide 3 mg and 4.5 mg Gastrointestinal Tolerability: Post-hoc Analysis of Incidence and Prevalence in Award-11 by VAN, JOANNA, FRIAS, JUAN P., BONORA, ENZO, RAHA, SOHINI, JUNG, HEIKE, COX, DAVID, KONIG, MANIGE, PELESHOK, JENNIFER

“…GLP-1 receptor agonists are associated with gastrointestinal adverse events (GI AEs). This post-hoc analysis of AWARD-11 in patients with inadequately…”
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