Search Results - "HEAGERTY, Patrick"

Clinical Manifestations of Kidney Disease Among US Adults With Diabetes, 1988-2014 by Afkarian, Maryam, Zelnick, Leila R, Hall, Yoshio N, Heagerty, Patrick J, Tuttle, Katherine, Weiss, Noel S, de Boer, Ian H

“…IMPORTANCE: Diabetic kidney disease is the leading cause of chronic and end-stage kidney disease in the United States and worldwide. Changes in demographics…”
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A Tutorial on Evaluating the Time-Varying Discrimination Accuracy of Survival Models Used in Dynamic Decision Making by Bansal, Aasthaa, Heagerty, Patrick J.

“…Many medical decisions involve the use of dynamic information collected on individual patients toward predicting likely transitions in their future health…”
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Indicators of retention in remote digital health studies: a cross-study evaluation of 100,000 participants by Pratap, Abhishek, Neto, Elias Chaibub, Snyder, Phil, Stepnowsky, Carl, Elhadad, Noémie, Grant, Daniel, Mohebbi, Matthew H., Mooney, Sean, Suver, Christine, Wilbanks, John, Mangravite, Lara, Heagerty, Patrick J., Areán, Pat, Omberg, Larsson

“…Digital technologies such as smartphones are transforming the way scientists conduct biomedical research. Several remotely conducted studies have recruited…”
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Mixed-effects models for the design and analysis of stepped wedge cluster randomized trials: An overview by Li, Fan, Hughes, James P, Hemming, Karla, Taljaard, Monica, Melnick, Edward R., Heagerty, Patrick J

“…The stepped wedge cluster randomized design has received increasing attention in pragmatic clinical trials and implementation science research. The key feature…”
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The Use and Effectiveness of Mobile Apps for Depression: Results From a Fully Remote Clinical Trial by Arean, Patricia A, Hallgren, Kevin A, Jordan, Joshua T, Gazzaley, Adam, Atkins, David C, Heagerty, Patrick J, Anguera, Joaquin A

“…Mobile apps for mental health have the potential to overcome access barriers to mental health care, but there is little information on whether patients use the…”
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Using Effect Scores to Characterize Heterogeneity of Treatment Effects by Wang, Guanbo, Heagerty, Patrick J, Dahabreh, Issa J

“…This JAMA Guide to Statistics and Methods article explains effect score analyses, an approach for evaluating the heterogeneity of treatment effects, and…”
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Description and initial validation of a novel measure of pain intensity: the Numeric Rating Scale of Underlying Pain without concurrent Analgesic use by Suri, Pradeep, Heagerty, Patrick J, Timmons, Andrew, Jensen, Mark P

“…Although many individuals with chronic pain use analgesics, the methods used in many randomized controlled trials (RCTs) do not sufficiently account for…”
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Planning stepped wedge cluster randomized trials to detect treatment effect heterogeneity by Li, Fan, Chen, Xinyuan, Tian, Zizhong, Wang, Rui, Heagerty, Patrick J.

“…Stepped wedge design is a popular research design that enables a rigorous evaluation of candidate interventions by using a staggered cluster randomization…”
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Temporal Trends in the Prevalence of Diabetic Kidney Disease in the United States by de Boer, Ian H, Rue, Tessa C, Hall, Yoshio N, Heagerty, Patrick J, Weiss, Noel S, Himmelfarb, Jonathan

“…CONTEXT Diabetes is the leading cause of kidney disease in the developed world. Over time, the prevalence of diabetic kidney disease (DKD) may increase due to…”
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Designing three-level cluster randomized trials to assess treatment effect heterogeneity by Li, Fan, Chen, Xinyuan, Tian, Zizhong, Esserman, Denise, Heagerty, Patrick J, Wang, Rui

“…SUMMARY Cluster randomized trials often exhibit a three-level structure with participants nested in subclusters such as health care providers, and subclusters…”
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Diabetes and CKD in the United States Population, 2009-2014 by Zelnick, Leila R, Weiss, Noel S, Kestenbaum, Bryan R, Robinson-Cohen, Cassianne, Heagerty, Patrick J, Tuttle, Katherine, Hall, Yoshio N, Hirsch, Irl B, de Boer, Ian H

“…Diabetes is an important cause of CKD. However, among people with diabetes, it is unclear to what extent CKD is attributable to diabetes itself versus comorbid…”
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Analysis of stepped wedge cluster randomized trials in the presence of a time‐varying treatment effect by Kenny, Avi, Voldal, Emily C., Xia, Fan, Heagerty, Patrick J., Hughes, James P.

“…Stepped wedge cluster randomized controlled trials are typically analyzed using models that assume the full effect of the treatment is achieved…”
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A Randomized Trial Comparing Antibiotics with Appendectomy for Appendicitis by Flum, David R, Davidson, Giana H, Monsell, Sarah E, Shapiro, Nathan I, Odom, Stephen R, Sanchez, Sabrina E, Drake, F Thurston, Fischkoff, Katherine, Johnson, Jeffrey, Patton, Joe H, Evans, Heather, Cuschieri, Joseph, Sabbatini, Amber K, Faine, Brett A, Skeete, Dionne A, Liang, Mike K, Sohn, Vance, McGrane, Karen, Kutcher, Matthew E, Chung, Bruce, Carter, Damien W, Ayoung-Chee, Patricia, Chiang, William, Rushing, Amy, Steinberg, Steven, Foster, Careen S, Schaetzel, Shaina M, Price, Thea P, Mandell, Katherine A, Ferrigno, Lisa, Salzberg, Matthew, DeUgarte, Daniel A, Kaji, Amy H, Moran, Gregory J, Saltzman, Darin, Alam, Hasan B, Park, Pauline K, Kao, Lillian S, Thompson, Callie M, Self, Wesley H, Yu, Julianna T, Wiebusch, Abigail, Winchell, Robert J, Clark, Sunday, Krishnadasan, Anusha, Fannon, Erin, Lavallee, Danielle C, Comstock, Bryan A, Bizzell, Bonnie, Heagerty, Patrick J, Kessler, Larry G, Talan, David A

“…In a randomized trial comparing antibiotic therapy with appendectomy in patients with appendicitis, antibiotics were noninferior on the basis of EQ-5D scores…”
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Survival Model Predictive Accuracy and ROC Curves by Heagerty, Patrick J., Zheng, Yingye

“…The predictive accuracy of a survival model can be summarized using extensions of the proportion of variation explained by the model, or R2, commonly used for…”
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A Randomized Trial of Vertebroplasty for Osteoporotic Spinal Fractures by Kallmes, David F, Comstock, Bryan A, Heagerty, Patrick J, Turner, Judith A, Wilson, David J, Diamond, Terry H, Edwards, Richard, Gray, Leigh A, Stout, Lydia, Owen, Sara, Hollingworth, William, Ghdoke, Basavaraj, Annesley-Williams, Deborah J, Ralston, Stuart H, Jarvik, Jeffrey G

“…In this randomized trial involving patients with osteoporotic vertebral compression fractures, patients who underwent vertebroplasty had improvements in pain…”
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High-Dose Erythropoietin and Hypothermia for Hypoxic-Ischemic Encephalopathy: A Phase II Trial by Wu, Yvonne W, Mathur, Amit M, Chang, Taeun, McKinstry, Robert C, Mulkey, Sarah B, Mayock, Dennis E, Van Meurs, Krisa P, Rogers, Elizabeth E, Gonzalez, Fernando F, Comstock, Bryan A, Juul, Sandra E, Msall, Michael E, Bonifacio, Sonia L, Glass, Hannah C, Massaro, An N, Dong, Lawrence, Tan, Katherine W, Heagerty, Patrick J, Ballard, Roberta A

“…To determine if multiple doses of erythropoietin (Epo) administered with hypothermia improve neuroradiographic and short-term outcomes of newborns with…”
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Robust inference for the stepped wedge design by Hughes, James P., Heagerty, Patrick J., Xia, Fan, Ren, Yuqi

“…Stepped wedge designed trials are a type of cluster‐randomized study in which the intervention is introduced to each cluster in a random order over time. This…”
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Effectiveness of Existing Insomnia Therapies for Patients Undergoing Hemodialysis : A Randomized Clinical Trial by Mehrotra, Rajnish, Cukor, Daniel, McCurry, Susan M, Rue, Tessa, Roumelioti, Maria-Eleni, Heagerty, Patrick J, Unruh, Mark

“…Chronic insomnia is common in patients undergoing in-center hemodialysis, yet there is limited evidence on effective treatments for this population. To compare…”
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How well does neonatal neuroimaging correlate with neurodevelopmental outcomes in infants with hypoxic-ischemic encephalopathy? by Wu, Yvonne W., Monsell, Sarah E., Glass, Hannah C., Wisnowski, Jessica L., Mathur, Amit M., McKinstry, Robert C., Bluml, Stefan, Gonzalez, Fernando F., Comstock, Bryan A., Heagerty, Patrick J., Juul, Sandra E.

“…Background In newborns with hypoxic-ischemic encephalopathy (HIE), the correlation between neonatal neuroimaging and the degree of neurodevelopmental…”
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Analysis of multiple-period group randomized trials: random coefficients model or repeated measures ANOVA? by Moyer, Jonathan C, Heagerty, Patrick J, Murray, David M

“…Multiple-period parallel group randomized trials (GRTs) analyzed with linear mixed models can represent time in mean models as continuous or categorical. If…”
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