Search Results - "HAZLEWOOD, GEOFFREY P"

Unusual microbial xylanases from insect guts by Brennan, Y.L, Callen, W.N, Christoffersen, L, Dupree, P, Goubet, F, Healey, S, Hernandez, M, Keller, M, Li, K, Palackal, N

“…Recombinant DNA technologies enable the direct isolation and expression of novel genes from biotopes containing complex consortia of uncultured microorganisms…”
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Discovery of Pectin-degrading Enzymes and Directed Evolution of a Novel Pectate Lyase for Processing Cotton Fabric by Solbak, Arne I., Richardson, Toby H., McCann, Ryan T., Kline, Katie A., Bartnek, Flash, Tomlinson, Geoff, Tan, Xuqiu, Parra-Gessert, Lilian, Frey, Gerhard J., Podar, Mircea, Luginbühl, Peter, Gray, Kevin A., Mathur, Eric J., Robertson, Dan E., Burk, Mark J., Hazlewood, Geoffrey P., Short, Jay M., Kerovuo, Janne

“…There is a growing need in the textile industry for more economical and environmentally responsible approaches to improve the scouring process as part of the…”
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Enhancing the Thermal Tolerance and Gastric Performance of a Microbial Phytase for Use as a Phosphate-Mobilizing Monogastric-Feed Supplement by GARRETT, James B, KRETZ, Keith A, O'DONOGHUE, Eileen, KEROVUO, Janne, KIM, William, BARTON, Nelson R, HAZLEWOOD, Geoffrey P, SHORT, Jay M, ROBERTSON, Dan E, GRAY, Kevin A

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A family IIb xylan-binding domain has a similar secondary structure to a homologous family IIa cellulose-binding domain but different ligand specificity by Simpson, Peter J, Bolam, David N, Cooper, Alan, Ciruela, Antonio, Hazlewood, Geoffrey P, Gilbert, Harry J, Williamson, Michael P

“…Background: Many enzymes that digest polysaccharides contain separate polysaccharide-binding domains. Structures have been previously determined for a number…”
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Characterization of a cellulosome dockerin domain from the anaerobic fungus Piromyces equi by Williamson, Michael P, Raghothama, S, Eberhardt, Ruth Y, Simpson, Peter, Wigelsworth, Darran, White, Peter, Hazlewood, Geoffrey P, Nagy, Tibor, Gilbert, Harry J

“…The recycling of photosynthetically fixed carbon in plant cell walls is a key microbial process. In anaerobes, the degradation is carried out by a high…”
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Structure of the catalytic core of the family F xylanase from Pseudomonas fluorescens and identification of the xylopentaose-binding sites by Harris, G W, Jenkins, J A, Connerton, I, Cummings, N, Lo Leggio, L, Scott, M, Hazlewood, G P, Laurie, J I, Gilbert, H J, Pickersgill, R W

“…Sequence alignment suggests that xylanases evolved from two ancestral proteins and therefore can be grouped into two families, designated F and G. Family F…”
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multifunctional hybrid glycosyl hydrolase discovered in an uncultured microbial consortium from ruminant gut by Palackal, Nisha, Lyon, Christopher S, Zaidi, Seema, Luginbühl, Peter, Dupree, Paul, Goubet, Florence, Macomber, John L, Short, Jay M, Hazlewood, Geoffrey P, Robertson, Dan E, Steer, Brian A

“…A unique multifunctional glycosyl hydrolase was discovered by screening an environmental DNA library prepared from a microbial consortium collected from cow…”
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An evolutionary route to xylanase process fitness by Palackal, Nisha, Brennan, Yali, Callen, Walter N., Dupree, Paul, Frey, Gerhard, Goubet, Florence, Hazlewood, Geoffrey P., Healey, Shaun, Kang, Young E., Kretz, Keith A., Lee, Edd, Tan, Xuqiu, Tomlinson, Geoffery L., Verruto, John, Wong, Vicky W.K., Mathur, Eric J., Short, Jay M., Robertson, Dan E., Steer, Brian A.

“…Directed evolution technologies were used to selectively improve the stability of an enzyme without compromising its catalytic activity. In particular, this…”
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Bacterial xylanase expression in mammalian cells and transgenic mice by Fontes, Carlos M.G.A., Ali, Simi, Gilbert, Harry J., Hazlewood, Geoffrey P., Hirst, Barry H., Hall, Judith

“…The energy which simple-stomached livestock can derive from dietary plant material is limited by the lack of plant polysaccharide degrading enzymes in their…”
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A Novel Carbohydrate-binding Protein Is a Component of the Plant Cell Wall-degrading Complex of Piromyces equi by Freelove, A C, Bolam, D N, White, P, Hazlewood, G P, Gilbert, H J

“…The recycling of photosynthetically fixed carbon by the action of microbial plant cell wall hydrolases is a fundamental biological process that is integral to…”
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Prebleaching of softwood and hardwood pulps by a high performance xylanase belonging to a novel clade of glycosyl hydrolase family 11 by Esteghlalian, Ali R., Kazaoka, Martin M., Lowery, Brad A., Varvak, Alexander, Hancock, Bill, Woodward, Thomas, Turner, Jack O., Blum, David L., Weiner, David, Hazlewood, Geoffrey P.

“…To discover and develop a xylanase enzyme that can significantly enhance wood pulp bleachability under typical kraft process conditions (high temperature and…”
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Homologous xylanases from Clostridium thermocellum: evidence for bi-functional activity, synergism between xylanase catalytic modules and the presence of xylan-binding domains in enzyme complexes by Fernandes, A.C, Fontes, C.M.G.A, Gilbert, H.J, Hazlewood, G.P, Fernandes, T.H, Ferreira, L.M.A

“…Clostridium thermocellum produces a consortium of plant-cell-wall hydrolases that form a cell-bound multi-enzyme complex called the cellulosome. In the present…”
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The Topology of the Substrate Binding Clefts of Glycosyl Hydrolase Family 10 Xylanases Are Not Conserved by Charnock, Simon J., Spurway, Tracey D., Xie, Hefang, Beylot, Marie-Hélène, Virden, Richard, Warren, R. Antony J., Hazlewood, Geoffrey P., Gilbert, Harry J.

“…The crystal structures of family 10 xylanases indicate that the distal regions of their active sites are quite different, suggesting that the topology of the…”
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Co-integration and expression of bacterial and genomic transgenes in the pancreatic and intestinal tissues of transgenic mice by Ali, Simi, Fontes, Carlos M.G.A, Hazlewood, Geoffrey P, Hirst, Barry H, Clark, A.John, Gilbert, Harry J, Hall, Judith

“…Previous studies in the mammary gland have reported the `rescue' of poorly expressed cDNA transgenes by their co-integration with a genomic sequence…”
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The conserved noncatalytic 40-residue sequence in cellulases and hemicellulases from anaerobic fungi functions as a protein docking domain by Fanutti, C. (The Babraham Institute, Babraham, Cambridge.), Ponyi, T, Black, G.W, Hazlewood, G.P, Gilbert, H.J

“…Two cDNAs, designated xynA and manA, encoding xylanase A (XYLA) and mannanase A (MANA), respectively, were isolated from a cDNA library derived from mRNA…”
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All three surface tryptophans in Type IIa cellulose binding domains play a pivotal role in binding both soluble and insoluble ligands by Nagy, Tibor, Simpson, Peter, Williamson, Michael P., Hazlewood, Geoffrey P., Gilbert, Harry J., Orosz, Laszlo

“…The three surface tryptophans of the Type IIa cellulose binding domain of Pseudomonas fluorescens subsp. cellulosa xylanase A (CBD XYLA) were independently…”
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family 26 mannanase produced by Clostridium thermocellum as a component of the cellulosome contains a domain which is conserved in mannanases from anaerobic fungi by Halstead, J.R, Vercoe, P.E, Gilbert, H.J, Davidson, K, Hazlewood, G.P

“…Cellulosomes prepared by the cellulose affinity digestion method from Clostridium thermocellum culture supernatant hydrolysed carob galactomannan during…”
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Arabinanase A from Pseudomonas fluorescens subsp. cellulosa exhibits both an endo- and an exo- mode of action by McKie, V A, Black, G W, Millward-Sadler, S J, Hazlewood, G P, Laurie, J I, Gilbert, H J

“…Pseudomonas fluorescens subsp. cellulosa expressed arabinanase activity when grown on media supplemented with arabinan or arabinose. Arabinanase activity was…”
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α-Galactosidase A from Pseudomonas fluorescens subsp. cellulosa: cloning, high level expression and its role in galactomannan hydrolysis by Halstead, Jonathan R., Fransen, Maikel P., Eberhart, Ruth Y., Park, Alison J., Gilbert, Harry J., Hazlewood, Geoffrey P.

“…A library of Pseudomonas fluorescens subsp. cellulosa genomic DNA, constructed in λ ZAPII, was screened for α- D-galactosidase activity. The DNA inserts from…”
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Synergistic interaction of the cellulosome integrating protein (CipA) from Clostridium thermocellum with a cellulosomal endoglucanase by Ciruela, Antonio, Gilbert, Harry J, Ali, Bassam R.S, Hazlewood, Geoffrey P

“…Activity of a cellulosomal endoglucanase (endoglucanase E; EGE) from Clostridium thermocellum against two crystalline forms of cellulose was enhanced by…”
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