Search Results - "HAZELBAUER, Gerald L"

Core unit of chemotaxis signaling complexes by Li, Mingshan, Hazelbauer, Gerald L

“…Bacterial chemoreceptors, histidine kinase CheA, and coupling protein CheW form clusters of chemotaxis signaling complexes. In signaling complexes kinase…”
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Bacterial Chemotaxis: The Early Years of Molecular Studies by Hazelbauer, Gerald L

“…This review focuses on the early years of molecular studies of bacterial chemotaxis and motility, beginning in the 1960s with Julius Adler's pioneering work…”
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Bacterial chemoreceptors: high-performance signaling in networked arrays by Hazelbauer, Gerald L., Falke, Joseph J., Parkinson, John S.

“…Chemoreceptors are crucial components in the bacterial sensory systems that mediate chemotaxis. Chemotactic responses exhibit exquisite sensitivity, extensive…”
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Selective allosteric coupling in core chemotaxis signaling complexes by Mingshan Li (李明山), Hazelbauer, Gerald L.

“…Bacterial chemotaxis is mediated by signaling complexes that sense chemical gradients and direct bacteria to favorable environments by controlling a histidine…”
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Bacterial chemoreceptors: providing enhanced features to two-component signaling by Hazelbauer, Gerald L, Lai, Wing-Cheung

“…Bacteria perform chemotaxis utilizing core two-component signaling systems to which have been added enhanced features of signal amplification, sensory…”
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A Selective Tether Recruits Activated Response Regulator CheB to Its Chemoreceptor Substrate by Li, Mingshan, Xu, Xianjin, Zou, Xiaoqin, Hazelbauer, Gerald L

“…Methylesterase/deamidase CheB is a key component of bacterial chemotaxis systems. It is also a prominent example of a two-component response regulator in which…”
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A dual regulation mechanism of histidine kinase CheA identified by combining network-dynamics modeling and system-level input-output data by Mello, Bernardo A, Pan, Wenlin, Hazelbauer, Gerald L, Tu, Yuhai

“…It is challenging to decipher molecular mechanisms in biological systems from system-level input-output data, especially for complex processes that involve…”
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Cellular Stoichiometry of the Components of the Chemotaxis Signaling Complex by Li, Mingshan, Hazelbauer, Gerald L

“…Article Usage Stats Services JB Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley…”
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Influence of Membrane Lipid Composition on a Transmembrane Bacterial Chemoreceptor by Amin, Divya N., Hazelbauer, Gerald L.

“…Most bacterial chemoreceptors are transmembrane proteins. Although less than 10% of a transmembrane chemoreceptor is embedded in lipid, separation from the…”
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Nanodiscs Separate Chemoreceptor Oligomeric States and Reveal Their Signaling Properties by Boldog, Thomas, Grimme, Stephen, Li, Mingshan, Sligar, Stephen G., Hazelbauer, Gerald L.

“…Bacterial chemoreceptors are transmembrane homodimers that can form trimers, higher order arrays, and extended clusters as part of signaling complexes…”
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Spatial Restrictions in Chemotaxis Signaling Arrays: A Role for Chemoreceptor Flexible Hinges across Bacterial Diversity by Stalla, David, Akkaladevi, Narahari, White, Tommi A, Hazelbauer, Gerald L

“…The chemotactic sensory system enables motile bacteria to move toward favorable environments. Throughout bacterial diversity, the chemoreceptors that mediate…”
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The Chemoreceptor Dimer Is the Unit of Conformational Coupling and Transmembrane Signaling by AMIN, Divya N, HAZELBAUER, Gerald L

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Using Nanodiscs to create water-soluble transmembrane chemoreceptors inserted in lipid bilayers by Boldog, Thomas, Li, Mingshan, Hazelbauer, Gerald L

“…In this chapter we describe application of the emerging technology of Nanodiscs to chemoreceptors, a class of transmembrane proteins that presents many…”
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Signaling and sensory adaptation in Escherichia coli chemoreceptors: 2015 update by Parkinson, John S, Hazelbauer, Gerald L, Falke, Joseph J

“…Highlights • Escherichia coli uses transmembrane chemoreceptors to detect environmental chemicals. • Chemoreceptors convey signals through dynamic shifts in…”
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Methyltransferase CheR binds to its chemoreceptor substrates independent of their signaling conformation yet modifies them differentially by Li, Mingshan, Hazelbauer, Gerald L.

“…Methylation of specific chemoreceptor glutamyl residues by methyltransferase CheR mediates sensory adaptation and gradient sensing in bacterial chemotaxis…”
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ATP Binding as a Key Target for Control of the Chemotaxis Kinase by Jun, Se-Young, Pan, Wenlin, Hazelbauer, Gerald L

“…In bacterial chemotaxis, chemoreceptors in signaling complexes modulate the activity of two-component histidine kinase CheA in response to chemical stimuli…”
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A nonequilibrium allosteric model for receptor-kinase complexes: The role of energy dissipation in chemotaxis signaling by Hathcock, David, Yu, Qiwei, Mello, Bernardo A, Amin, Divya N, Hazelbauer, Gerald L, Tu, Yuhai

“…The chemotaxis signaling pathway has served as a model system for the adaptive sensing of environmental signals by large protein complexes. The chemoreceptors…”
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Bacterial Chemoreceptor Dynamics: Helical Stability in the Cytoplasmic Domain Varies with Functional Segment and Adaptational Modification by Bartelli, Nicholas L., Hazelbauer, Gerald L.

“…Dynamics are thought to be important features of structure and signaling in the cytoplasmic domain of bacterial chemoreceptors. However, little is known about…”
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Flexible Hinges in Bacterial Chemoreceptors by Akkaladevi, Narahari, Bunyak, Filiz, Stalla, David, White, Tommi A, Hazelbauer, Gerald L

“…Transmembrane bacterial chemoreceptors are extended, rod-shaped homodimers with ligand-binding sites at one end and interaction sites for signaling complex…”
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Signaling complexes control the chemotaxis kinase by altering its apparent rate constant of autophosphorylation by Pan, Wenlin, Dahlquist, Frederick W., Hazelbauer, Gerald L.

“…Autophosphorylating histidine kinase CheA is central to signaling in bacterial chemotaxis. The kinase donates its phosphoryl group to two response regulators,…”
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