Search Results - "HAYWARD, S. W"

Inhibition of NF-kappa B signaling restores responsiveness of castrate-resistant prostate cancer cells to anti-androgen treatment by decreasing androgen receptor-variant expression by Jin, R, Yamashita, H, Yu, X, Wang, J, Franco, O E, Wang, Y, Hayward, S W, Matusik, R J

“…Androgen receptor splicing variants (ARVs) that lack the ligand-binding domain (LBD) are associated with the development of castration-resistant prostate…”
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Investigating prostate cancer tumour–stroma interactions: clinical and biological insights from an evolutionary game by Basanta, D, Scott, J G, Fishman, M N, Ayala, G, Hayward, S W, Anderson, A R A

“…Background: Tumours are made up of a mixed population of different types of cells that include normal structures as well as ones associated with the…”
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Identification of stromally expressed molecules in the prostate by tag-profiling of cancer-associated fibroblasts, normal fibroblasts and fetal prostate by Orr, B, Riddick, A C P, Stewart, G D, Anderson, R A, Franco, O E, Hayward, S W, Thomson, A A

“…The stromal microenvironment has key roles in prostate development and cancer, and cancer-associated fibroblasts (CAFs) stimulate tumourigenesis via several…”
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Pim1 kinase synergizes with c-MYC to induce advanced prostate carcinoma by Wang, J, Kim, J, Roh, M, Franco, O E, Hayward, S W, Wills, M L, Abdulkadir, S A

“…The oncogenic PIM1 kinase has been implicated as a cofactor for c-MYC in prostate carcinogenesis. In this study, we show that in human prostate tumors,…”
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Prostate tumor progression is mediated by a paracrine TGF-β Wnt3a signaling axis by Li, X, Placencio, V, Iturregui, J M, Uwamariya, C, Sharif-Afshar, A-R, Koyama, T, Hayward, S W, Bhowmick, N A

“…Transforming growth factor (TGF)-β is an important paracrine factor in tumorigenesis. Ligand binding of the type I and II TGF-β receptors initiate downstream…”
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SOX2 expression in the developing, adult, as well as, diseased prostate by Yu, X, Cates, J M, Morrissey, C, You, C, Grabowska, M M, Zhang, J, DeGraff, D J, Strand, D W, Franco, O E, Lin-Tsai, O, Hayward, S W, Matusik, R J

“…Background: SOX2 is a member of SOX (SRY-related high mobility group box) family of transcription factors. Methods: In this study, we examined the expression…”
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Carcinoma-associated fibroblasts direct tumor progression of initiated human prostatic epithelium by OLUMI, A. F, GROSSFELD, G. D, HAYWARD, S. W, CARROLL, P. R, TLSTY, T. D, CUNHA, G. R

“…The present study demonstrates that fibroblasts associated with carcinomas stimulate tumor progression of initiated nontumorigenic epithelial cells both in an…”
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bic, a novel gene activated by proviral insertions in avian leukosis virus-induced lymphomas, is likely to function through its noncoding RNA by Tam, Wayne, Ben-Yehuda, Dina, Hayward, William S.

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Interactions between adult human prostatic epithelium and rat urogenital sinus mesenchyme in a tissue recombination model by Hayward, Simon W., Haughney, Peter C., Rosen, Mark A., Greulich, Karin M., Weier, Heinz-Ulrich G., Dahiya, Rajvir, Cunha, Gerald R.

“…Tissue recombinants composed of adult human prostatic epithelium (hPrE) and rat urogenital sinus mesenchyme (rUGM) were grafted beneath the renal capsule of…”
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Regeneration of bladder urothelium, smooth muscle, blood vessels and nerves into an acellular tissue matrix by Sutherland, R S, Baskin, L S, Hayward, S W, Cunha, G R

“…To study the cellular events occurring during bladder development and regeneration we developed an in vivo model of bladder augmentation with an acellular…”
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Establishment and Characterization of an Immortalized but Non-Transformed Human Prostate Epithelial Cell Line: BPH-1 by S. W. Hayward, R. Dahiya, Cunha, G. R., J. Bartek, N. Deshpande, P. Narayan

“…This report describes the development and characterization of an epithelial cell line (BPH-1) from human prostate tissue obtained by transurethral resection…”
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Hypoxia and the metabolic phenotype of prostate cancer cells by Higgins, L.H., Withers, H.G., Garbens, A., Love, H.D., Magnoni, L., Hayward, S.W., Moyes, C.D.

“…Many cancer cells have an unusual ability to grow in hypoxia, but the origins of this metabolic phenotype remain unclear. We compared the metabolic phenotypes…”
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The role of stroma in prostatic carcinogenesis by Grossfeld, G D, Hayward, S W, Tlsty, T D, Cunha, G R

“…Most human prostate tumors are adenocarcinomas which arise from the epithelial cells that line the glands and ducts of the prostate. Consequently, the…”
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Role of mesenchymal-epithelial interactions in normal bladder development by Baskin, L S, Hayward, S W, Young, P, Cunha, G R

“…To assess the role of cell-cell interactions in the development of bladder smooth muscle. Bladders from 14-day rat fetuses (prior to smooth muscle…”
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Multiple proto-oncogene activations in avian leukosis virus-induced lymphomas: evidence for stage-specific events by CLURMAN, B. E, HAYWARD, W. S

“…Article Usage Stats Services MCB Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley…”
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PPARγ isoforms differentially regulate metabolic networks to mediate mouse prostatic epithelial differentiation by Strand, D W, Jiang, M, Murphy, T A, Yi, Y, Konvinse, K C, Franco, O E, Wang, Y, Young, J D, Hayward, S W

“…Recent observations indicate prostatic diseases are comorbidities of systemic metabolic dysfunction. These discoveries revealed fundamental questions regarding…”
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Estrogenic effects on prostatic differentiation and carcinogenesis by Cunha, G R, Wang, Y Z, Hayward, S W, Risbridger, G P

“…Estrogens, alone or in combination with androgens, can induce aberrant growth and/or malignancy of the prostate gland. Squamous metaplasia is an abnormal form…”
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Disruption of PPARγ signaling results in mouse prostatic intraepithelial neoplasia involving active autophagy by Jiang, M, Fernandez, S, Jerome, W G, He, Y, Yu, X, Cai, H, Boone, B, Yi, Y, Magnuson, M A, Roy-Burman, P, Matusik, R J, Shappell, S B, Hayward, S W

“…Peroxisome proliferator-activated receptor-gamma (PPAR γ ) regulates the interface between cellular lipid metabolism, redox status and organelle…”
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Growth factors in bladder wound healing by Baskin, L S, Sutherland, R S, Thomson, A A, Nguyen, H T, Morgan, D M, Hayward, S W, Hom, Y K, DiSandro, M, Cunha, G R

“…Surgical and traumatic injuries to the bladder initiate a complex series of biological processes that result in wound healing. This process involves cellular…”
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Loss of TGF-β type II receptor in fibroblasts promotes mammary carcinoma growth and invasion through upregulation of TGF-α-, MSP- and HGF-mediated signaling networks by CHENG, Nikki, BHOWMICK, Neil A, CHYTIL, Anna, GORKSA, Agnieszka E, BROWN, Kimberly A, MURAOKA, Rebecca, ARTEAGA, Carlos L, NEILSON, Eric G, HAYWARD, Simon W, MOSES, Harold L

“…Stromal fibroblasts regulate epithelial cell behavior through direct and indirect cell-cell interactions. To clarify the role of TGF-beta signaling in stromal…”
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