Search Results - "HAYWARD, Gary S"

The Ubiquitin E3 Ligase RAUL Negatively Regulates Type I Interferon through Ubiquitination of the Transcription Factors IRF7 and IRF3 by Yu, Yanxing, Hayward, Gary S.

“…In the course of combating infectious agents, type I interferon (IFN) needs a timely downregulation mechanism to avoid detrimental overreaction. Here we showed…”
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Review of Elephant Endotheliotropic Herpesviruses and Acute Hemorrhagic Disease by Long, Simon Y., Latimer, Erin M., Hayward, Gary S.

“…More than 100 young captive and wild Asian elephants are known to have died from a rapid-onset, acute hemorrhagic disease caused primarily by multiple distinct…”
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Elephant Endotheliotropic Herpesvirus Hemorrhagic Disease in Asian Elephant Calves in Logging Camps, Myanmar by Oo, Zaw Min, Aung, Ye Htut, Aung, Tin Tun, San, Nyo, Tun, Zaw Min, Hayward, Gary S, Zachariah, Arun

“…In recent years, an alarming number of cases of lethal acute hemorrhagic disease have occurred in Asian elephant calves raised in logging camps in Myanmar. To…”
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Conservation: clarifying the risk from herpesvirus to captive Asian elephants by Hayward, Gary S.

“…Up to 24 per cent of Asian elephant calves born in North America and Europe within the past 20 years have been affected by this disease and it has been…”
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Analysis of human cytomegalovirus-encoded SUMO targets and temporal regulation of SUMOylation of the immediate-early proteins IE1 and IE2 during infection by Kim, Eui Tae, Kim, Young-Eui, Kim, Ye Ji, Lee, Myoung Kyu, Hayward, Gary S, Ahn, Jin-Hyun

“…Post-translational modification of proteins by members of the small ubiquitin-like modifier (SUMO) is involved in diverse cellular functions. Many viral…”
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Detection and evaluation of novel herpesviruses in routine and pathological samples from Asian and African elephants: Identification of two new probosciviruses (EEHV5 and EEHV6) and two new gammaherpesviruses (EGHV3B and EGHV5) by Latimer, Erin, Zong, Jian-Chao, Heaggans, Sarah Y., Richman, Laura K., Hayward, Gary S.

“…Systemic infections with elephant endotheliotropic herpesviruses (EEHV) cause a rapid onset acute hemorrhagic disease with an 85% mortality rate. More than 60…”
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Comparative genome analysis of four elephant endotheliotropic herpesviruses, EEHV3, EEHV4, EEHV5, and EEHV6, from cases of hemorrhagic disease or viremia by Zong, Jian-Chao, Latimer, Erin M, Long, Simon Y, Richman, Laura K, Heaggans, Sarah Y, Hayward, Gary S

“…The genomes of three types of novel endotheliotropic herpesviruses (elephant endotheliotropic herpesvirus 1A [EEHV1A], EEHV1B, and EEHV2) associated with…”
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Binding STAT2 by the Acidic Domain of Human Cytomegalovirus IE1 Promotes Viral Growth and Is Negatively Regulated by SUMO by Huh, Yong Ho, Kim, Young Eui, Kim, Eui Tae, Park, Jung Jin, Song, Moon Jung, Zhu, Hua, Hayward, Gary S, Ahn, Jin-Hyun

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Detection of pathogenic elephant endotheliotropic herpesvirus in routine trunk washes from healthy adult Asian elephants (Elephas maximus) by use of a real-time quantitative polymerase chain reaction assay by Stanton, Jeffrey J, Zong, Jian-Chao, Latimer, Erin, Tan, Jie, Herron, Alan, Hayward, Gary S, Ling, Paul D

“…To investigate the pathogenesis and transmission of elephant endotheliotropic herpesvirus (EEHV1) by analyzing various elephant fluid samples with a novel…”
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Primary Infection May Be an Underlying Factor Contributing to Lethal Hemorrhagic Disease Caused by Elephant Endotheliotropic Herpesvirus 3 in African Elephants ( Loxodonta africana ) by Pursell, Taylor, Spencer Clinton, Jennifer L, Tan, Jie, Peng, Rongsheng, Qin, Xiang, Doddapaneni, Harshavardhan, Menon, Vipin, Momin, Zeineen, Kottapalli, Kavya, Howard, Lauren, Latimer, Erin, Heaggans, Sarah, Hayward, Gary S, Ling, Paul D

“…Distinct but related species of elephant endotheliotropic herpesviruses (EEHVs) circulate within Asian and African elephant populations. Primary infection with…”
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Protein Array Identification of Substrates of the Epstein-Barr Virus Protein Kinase BGLF4 by JIAN ZHU, GANGLING LIAO, LIANG SHAN, JUN ZHANG, CHEN, Mei-Ru, HAYWARD, Gary S, HAYWARD, S. Diane, DESAI, Prashant, HENG ZHU

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Complete Genome Sequence of the English Isolate of Rat Cytomegalovirus (Murid Herpesvirus 8) by ETTINGER, Jakob, GEYER, Henriette, NITSCHE, Andreas, ZIMMERMANN, Albert, BRUNE, Wolfram, SANDFORD, Gordon R, HAYWARD, Gary S, VOIGT, Sebastian

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Conserved Herpesvirus Kinases Target the DNA Damage Response Pathway and TIP60 Histone Acetyltransferase to Promote Virus Replication by Li, Renfeng, Zhu, Jian, Xie, Zhi, Liao, Gangling, Liu, Jianyong, Chen, Mei-Ru, Hu, Shaohui, Woodard, Crystal, Lin, Jimmy, Taverna, Sean D., Desai, Prashant, Ambinder, Richard F., Hayward, Gary S., Qian, Jiang, Zhu, Heng, Hayward, S. Diane

“…Herpesviruses, which are major human pathogens, establish life-long persistent infections. Although the α, β, and γ herpesviruses infect different tissues and…”
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Detection of a single identical cytomegalovirus (CMV) strain in recently seroconverted young women by Murthy, Suchetha, Hayward, Gary S, Wheelan, Sarah, Forman, Michael S, Ahn, Jin-Hyun, Pass, Robert F, Arav-Boger, Ravit

“…Infection with multiple CMV strains is common in immunocompromised hosts, but its occurrence in normal hosts has not been well-studied. We analyzed CMV strains…”
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Development and validation of quantitative real-time polymerase chain reaction assays to detect elephant endotheliotropic herpesviruses-2, 3, 4, 5, and 6 by Stanton, Jeffrey J., Nofs, Sally A., Peng, Rongsheng, Hayward, Gary S., Ling, Paul D.

“…► Real-time PCR assays were developed for EEHV2, 3, 4, 5, and 6. ► The new EEHV assays are sensitive and specific. ► The assays are useful for determining EEHV…”
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Initiation of angiogenic Kaposi's sarcoma lesions by Hayward, Gary S

“…A new mouse model reported in this issue of Cancer Cell implies that VEGF/KDR-mediated paracrine effects induced by the lytic cycle vGPCR signaling protein…”
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Comparison of Humoral Immune Responses to Epstein-Barr Virus and Kaposi's Sarcoma—Associated Herpesvirus Using a Viral Proteome Microarray by Zheng, Dasheng, Wan, Jun, Cho, Yong Gu, Wang, Leyao, Chiou, Chuang-Jiun, Pai, Shweta, Woodard, Crystal, Zhu, Jian, Liao, Gangling, Martinez-Maza, Otoniel, Qian, Jiang, Zhu, Heng, Hayward, Gary S., Ambinder, Richard F., Hayward, S. Diane

“…Background. Epstein-Barr virus (EBV) is a ubiquitous herpesvirus, and Kaposi's sarcoma-associated herpesvirus (KSHV) has a restricted seroprevalence. Both…”
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Recombinant luciferase-expressing human cytomegalovirus (CMV) for evaluation of CMV inhibitors by He, Ran, Sandford, Gordon, Hayward, Gary S, Burns, William H, Posner, Gary H, Forman, Michael, Arav-Boger, Ravit

“…Recombinant Towne CMV expressing luciferase under the control of CMV-DNA polymerase (POL) or the late pp28 (UL99) promoters were evaluated for potential…”
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Ability of the Human Cytomegalovirus IE1 Protein To Modulate Sumoylation of PML Correlates with Its Functional Activities in Transcriptional Regulation and Infectivity in Cultured Fibroblast Cells by LEE, Hye-Ra, KIM, Do-Jun, LEE, Jang-Mi, CHEOL YONG CHOI, AHN, Byung-Yoon, HAYWARD, Gary S, AHN, Jin-Hyun

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CCAAT/Enhancer-Binding Protein-α Is Induced during the Early Stages of Kaposi's Sarcoma-Associated Herpesvirus (KSHV) Lytic Cycle Reactivation and Together with the KSHV Replication and Transcription Activator (RTA) Cooperatively Stimulates the Viral RTA, MTA, and PAN Promoters by Wang, Shizhen Emily, Wu, Frederick Y, Yu, Yanxing, Hayward, Gary S

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