Search Results - "HAYLOR, J. L"

Localization of matrix metalloproteinases and their inhibitors in experimental progressive kidney scarring by Ahmed, A.K., Haylor, J.L., El Nahas, A.M., Johnson, T.S.

“…The extracellular matrix (ECM) is in a continual state of turnover with homeostasis maintained by balancing synthesis and degradation rates. During progressive…”
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Factors influencing long-term outcomes following renal transplantation: a review by Shrestha, B M, Haylor, J L

“…Despite continuing advances in immunosuppressive and supportive therapies, the success of renal transplantation is impacted by factors present in the donor and…”
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Inhibition of compensatory renal growth by the N-terminus of a sheep-derived peptide by Haylor, J.L., Parker, E., Risbridger, G.P., Beale, D., Brown, B.L., Dobson, P.R.M., Clarke, I.J., Hart, J.E.

“…The N-terminal sequence of a novel sheep-derived peptide with growth inhibitory activity has been obtained. The N-terminal fragment was chemically synthesised…”
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Caspase-3 and apoptosis in experimental chronic renal scarring by Yang, Bin, El Nahas, A. Meguid, Thomas, Graham L., Haylor, John L., Watson, Philip F., Wagner, Bart, Johnson, Timothy S.

“…Caspase-3 and apoptosis in experimental chronic renal scarring. Caspase-3 is a member of the caspase enzyme family, having a central role in the execution of…”
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Feline Chronic Kidney Disease Is Associated With Upregulation of Transglutaminase 2: A Collagen Cross-Linking Enzyme by Sánchez-Lara, A. C., Elliott, J., Syme, H. M., Brown, C. A., Haylor, J. L.

“…Chronic kidney disease is a major cause of morbidity and mortality in cats. Transglutaminase 2 (TG2) is a calcium-dependent enzyme proposed to mediate…”
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Transglutaminase transcription and antigen translocation in experimental renal scarring by JOHNSON, T. S, SKILL, N. J, EL NAHAS, A. M, OLDROYD, S. D, THOMAS, G. L, DOUTHWAITE, J. A, HAYLOR, J. L, GRIFFIN, M

“…It was recently demonstrated that renal tissue transglutaminase (tTg) protein and its catalytic product the epsilon(gamma-glutamyl) lysine protein cross-link…”
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Bosentan, an orally active endothelin antagonist: effect on the renal response to contrast media by Oldroyd, S D, Haylor, J L, Morcos, S K

“…To examine the effect of bosentan, an orally active endothelin-receptor antagonist, on the renal response to contrast media in the isolated perfused rat kidney…”
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The Effect of Body Temperature in a Rat Model of Renal Ischemia-Reperfusion Injury by Delbridge, M.S, Shrestha, B.M, Raftery, A.T, El Nahas, A.M, Haylor, J.L

“…Abstract Background Renal ischemia-reperfusion injury (IRI) is an unavoidable event in renal transplantation; the effects of IRI can be seen in both the acute…”
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Effects of adenosine receptor antagonists on the responses to contrast media in the isolated rat kidney by Oldroyd, S D, Fang, L, Haylor, J L, Yates, M S, El Nahas, A M, Morcos, S K

“…Contrast media can induce both a decrease in renal blood flow and a reduction in glomerular filtration rate (GFR) when administered to both experimental…”
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The acute effect of ioversol on kidney function: role of endothelin by Oldroyd, S.D., Haylor, J.L., Morcos, S.K.

“…The effect of ioversol, a non-ionic monomer with high hydrophilicity, on renal function was studied using the isolated perfused rat kidney (IPRK). The…”
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IGF-I inhibitors reduce compensatory hyperfiltration in the isolated rat kidney following unilateral nephrectomy by Haylor, John L., Mckillop, Iain H., Oldroyd, Simon D., El Nahas, Meguid A.

“…Background. A role for insulin-like growth factor-I (IGF-I) as a mediator of renal hyperfiltration and hyperperfusion following unilateral nephrectomy (UNx)…”
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Haemodynamic effects of water-soluble contrast media on the isolated perfused rat kidney by el Sayed, A A, Haylor, J L, el Nahas, A M, Salzano, S, Morcos, S K

“…The precise mechanism underlying the nephrotoxicity of radiocontrast media remains ill defined. In this study we have examined the direct effect of a wide…”
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Stem cell factor in a rat model of serum nephrotoxic nephritis by El Kossi, M M, Haylor, J L, Johnson, T S, El Nahas, A M

“…Stem cell factor (SCF) has been implicated in many disease processes characterized by tissue remodelling and fibrosis. The growth factor (SCF) was evaluated in…”
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Expression of apoptosis-related genes and proteins in experimental chronic renal scarring by BIN YANG, JOHNSON, Timothy S, THOMAS, Graham L, WATSON, Philip F, WAGNER, Bart, SKILL, Nicholas J, HAYLOR, John L, EL NAHAS, A. Meguid

“…Apoptosis has been proposed to play an important role in the progression of renal scarring. The mechanisms that determine whether a cell enters the apoptotic…”
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Endothelin antagonism and contrast nephropathy by Haylor, John L., Morcos, Sameh K.

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Increases in Renal ε-(γ-Glutamyl)-Lysine Crosslinks Result from Compartment-Specific Changes in Tissue Transglutaminase in Early Experimental Diabetic Nephropathy: Pathologic Implications by Skill, N James, Griffin, Martin, El Nahas, A Meguid, Sanai, Toru, Haylor, John L, Fisher, Marie, Jamie, Mathew F, Mould, Nigel N, Johnson, Timothy S

“…Diabetic nephropathy (DN) is characterized by an early, progressive expansion and sclerosis of the glomerular mesangium leading to glomerulosclerosis. This is…”
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Cyclosporine A sensitizes the kidney to tubulointerstitial fibrosis induced by renal warm ischemia by AHMED, Ahmed, LINGHONG HUANG, RAFYERY, Andrew T, AHMED, Aimun K, FAHMY, Hossam, MEGUID EL NAHAS, A, HAYLOR, John L

“…Renal warm ischemic injury and immunosuppression with cyclosporin A (CsA) may contribute to chronic allograft nephropathy after cadaveric transplantation. This…”
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The functional effects of gadolinium-DTPA on the isolated perfused rat kidney by Brown, P W, Haylor, J L, Morcos, S K, el Nahas, A M

“…Clinical experience suggests that Gd-DTPA has no deleterious effect on renal function. We have evaluated the effects of a large dose (0.6 ml/kg body weight) of…”
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The functional effects of contrast media on the isolated perfused rat kidney by Brown, P W, Haylor, J L, el Nahas, A M, Morcos, S K

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The effect of sodium iothalamate on the vascular resistance of the isolated perfused rat kidney by Haylor, J L, el Sayed, A A, el Nahas, A M, Morcos, S K

“…The direct effects of sodium iothalamate on renal vascular resistance (RVR) were examined using the isolated perfused rat kidney experimental model. A…”
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