Search Results - "HAWKRIDGE, Anthony"
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Utilisation of private general practitioners to provide caesarean deliveries in five rural district public hospitals in South Africa: a mixed-methods study
Published in BMJ open (01-03-2023)“…ObjectiveResearching how public–private engagements may promote universal access to safe obstetric care including caesarean delivery is essential. The aim of…”
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COVID-19 Vaccine Uptake and Effectiveness by Time since Vaccination in the Western Cape Province, South Africa: An Observational Cohort Study during 2020-2022
Published in Vaccines (Basel) (01-06-2024)“…There are few data on the real-world effectiveness of COVID-19 vaccines and boosting in Africa, which experienced widespread SARS-CoV-2 infection before…”
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Association of human TLR1 and TLR6 deficiency with altered immune responses to BCG vaccination in South African infants
Published in PLoS pathogens (01-08-2011)“…The development of effective immunoprophylaxis against tuberculosis (TB) remains a global priority, but is hampered by a partially protective Bacillus…”
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4
Clinical studies of TB vaccines
Published in Human vaccines (01-11-2009)“…Tuberculosis will not be brought under control without a more effective TB vaccine being made available. The only currently licensed TB vaccine, BCG, was…”
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Advances in childhood immunisation in South Africa: where to now? Programme managers' views and evidence from systematic reviews
Published in BMC public health (31-07-2012)“…The Expanded Programme on Immunisation (EPI) is one of the most powerful and cost-effective public health programmes to improve child survival. We assessed…”
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The Effect of Bacille Calmette-Guérin Vaccine Strain and Route of Administration on Induced Immune Responses in Vaccinated Infants
Published in The Journal of infectious diseases (15-02-2006)“…Vaccination with Mycobacterium bovis bacille Calmette-Guérin (BCG) has variable efficacy in preventing tuberculosis. Both BCG strain and route of…”
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Advocating for efforts to protect African children, families, and communities from the threat of infectious diseases: report of the First International African Vaccinology Conference
Published in The Pan African medical journal (2016)“…One means of improving healthcare workers' knowledge of and attitudes to vaccines is through running vaccine conferences which are accessible, affordable, and…”
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Journal Article Conference Proceeding -
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Dose-Dependent Immune Response to Mycobacterium bovis BCG Vaccination in Neonates
Published in Clinical and Vaccine Immunology (01-02-2007)“…Classifications Services CVI Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley Reddit…”
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Examining sustained sub-national health system development: experience from the Western Cape province, South Africa, 1994-2016
Published in Health policy and planning (14-11-2024)“…Governance and leadership are recognised as central to health system development in low- and middle-income countries, yet few existing studies consider the…”
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Specific T Cell Frequency and Cytokine Expression Profile Do Not Correlate with Protection against Tuberculosis after Bacillus Calmette-Guérin Vaccination of Newborns
Published in American journal of respiratory and critical care medicine (15-10-2010)“…Immunogenicity of new tuberculosis (TB) vaccines is commonly assessed by measuring the frequency and cytokine expression profile of T cells. We tested whether…”
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Health through human settlements: Investigating policymakers’ perceptions of human settlement action for population health improvement in urban South Africa
Published in Habitat international (01-09-2020)“…Informal settlements, characterised by inadequate living conditions and high disease burdens, continue to grow in response to rapid urban development in the…”
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Antigen-specific T Cell Activation Distinguishes Between Recent and Remote Tuberculosis Infection
Published in American journal of respiratory and critical care medicine (15-06-2021)“…Current diagnostic tests fail to identify individuals at higher risk of progression to tuberculosis disease, such as those with recent Mycobacterium…”
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Induction and Regulation of T-Cell Immunity by the Novel Tuberculosis Vaccine M72/AS01 in South African Adults
Published in American journal of respiratory and critical care medicine (15-08-2013)“…Tuberculosis (TB) is a major cause of morbidity and mortality worldwide, thus there is an urgent need for novel TB vaccines. We investigated a novel TB vaccine…”
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The Novel Tuberculosis Vaccine, AERAS-402, Induces Robust and Polyfunctional CD4+ and CD8+ T Cells in Adults
Published in American journal of respiratory and critical care medicine (15-06-2010)“…AERAS-402 is a novel tuberculosis vaccine designed to boost immunity primed by bacillus Calmette-Guérin (BCG), the only licensed vaccine. We investigated the…”
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Modified vaccinia Ankara-expressing Ag85A, a novel tuberculosis vaccine, is safe in adolescents and children, and induces polyfunctional CD4⁺ T cells
Published in European journal of immunology (2010)“…Modified vaccinia Ankara-expressing Ag85A (MVA85A) is a new tuberculosis (TB) vaccine aimed at enhancing immunity induced by BCG. We investigated the safety…”
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Bacillus Calmette-Guerin Vaccination of Human Newborns Induces T Cells with Complex Cytokine and Phenotypic Profiles
Published in The Journal of immunology (1950) (01-03-2008)“…The immune response to vaccination with bacillus Calmette-Guérin (BCG), the only tuberculosis vaccine available, has not been fully characterized. We used…”
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Childhood tuberculosis: progress requires an advocacy strategy now
Published in The European respiratory journal (01-08-2012)“…Childhood tuberculosis (TB) is a preventable and curable infectious disease that remains overlooked by public health authorities, health policy makers and TB…”
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Journal Article Conference Proceeding -
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BCG and New Preventive Tuberculosis Vaccines: Implications for Healthcare Workers
Published in Clinical infectious diseases (15-05-2016)“…Healthcare workers (HCWs) are at high risk of Mycobacterium tuberculosis (Mtb) infection and tuberculosis disease, but also play a crucial role in implementing…”
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Human newborn bacille Calmette-Guérin vaccination and risk of tuberculosis disease: a case-control study
Published in BMC medicine (16-05-2016)“…An incomplete understanding of the immunological mechanisms underlying protection against tuberculosis (TB) hampers the development of new vaccines against TB…”
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A phase IIa trial of the new tuberculosis vaccine, MVA85A, in HIV- and/or Mycobacterium tuberculosis-infected adults
Published in American journal of respiratory and critical care medicine (01-04-2012)“…Novel tuberculosis (TB) vaccines should be safe and effective in populations infected with Mycobacterium tuberculosis (M.tb) and/or HIV for effective TB…”
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