Search Results - "HAVIGHURST, THOMAS C"

Comparative Validity of Physical Activity Measures in Older Adults by COLBERT, Lisa H, MATTHEWS, Charles E, HAVIGHURST, Thomas C, KIM, Kyungmann, SCHOELLER, Dale A

“…To compare the validity of various physical activity measures with doubly labeled water (DLW)-measured physical activity energy expenditure (PAEE) in…”
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Multifunctional nanoparticle potentiates the in situ vaccination effect of radiation therapy and enhances response to immune checkpoint blockade by Zhang, Ying, Sriramaneni, Raghava N., Clark, Paul A., Jagodinsky, Justin C., Ye, Mingzhou, Jin, Wonjong, Wang, Yuyuan, Bates, Amber, Kerr, Caroline P., Le, Trang, Allawi, Raad, Wang, Xiuxiu, Xie, Ruosen, Havighurst, Thomas C., Chakravarty, Ishan, Rakhmilevich, Alexander L., O’Leary, Kathleen A., Schuler, Linda A., Sondel, Paul M., Kim, Kyungmann, Gong, Shaoqin, Morris, Zachary S.

“…Radiation therapy (RT) activates an in situ vaccine effect when combined with immune checkpoint blockade (ICB), yet this effect may be limited because RT does…”
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A Phase II Randomized, Double-blind, Presurgical Trial of Polyphenon E in Bladder Cancer Patients to Evaluate Pharmacodynamics and Bladder Tissue Biomarkers by Gee, Jason R, Saltzstein, Daniel R, Kim, KyungMann, Kolesar, Jill, Huang, Wei, Havighurst, Thomas C, Wollmer, Barbara W, Stublaski, Jeanne, Downs, Tracy, Mukhtar, Hasan, House, Margaret G, Parnes, Howard L, Bailey, Howard H

“…We performed a phase II pharmacodynamic prevention trial of Polyphenon E [a green tea polyphenol formulation primarily consisting of epigallocatechin gallate…”
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Local TLR4 stimulation augments in situ vaccination induced via local radiation and anti-CTLA-4 checkpoint blockade through induction of CD8 T-cell independent Th1 polarization by Jagodinsky, Justin C, Bates, Amber M, Clark, Paul A, Sriramaneni, Raghava N, Havighurst, Thomas C, Chakravarty, Ishan, Nystuen, Erin J, Kim, KyungMann, Sondel, Paul M, Jin, Won Jong, Morris, Zachary S

“…BackgroundRadiation therapy (RT) has been demonstrated to generate an in situ vaccination (ISV) effect in murine models and in patients with cancer; however,…”
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PROGNOSTIC SIGNIFICANCE OF TUMOR HISTOLOGY AND COMPUTED TOMOGRAPHIC STAGING FOR RADIATION TREATMENT RESPONSE OF CANINE NASAL TUMORS by ADAMS, WILLIAM M, KLEITER, MIRIAM M, THRALL, DONALD E, KLAUER, JULIA M, FORREST, LISA J, LA DUE, TRACY A, HAVIGHURST, THOMAS C

“…Prognostic significance of tumor histology and four computed tomography (CT) staging methods was tested retrospectively in dogs from three treatment centers…”
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Adverse Effects of Low Dose Amiodarone: A Meta-Analysis by Vorperian, Vicken R, Havighurst, Thomas C, Miller, Stephen, January, Craig T

“…Objectives. We sought to assess the odds of experiencing adverse effects with low dose amiodarone therapy compared with placebo. Background. An estimate of the…”
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Meta-analysis of randomized control trials addressing brief interventions in heavy alcohol drinkers by WILK, A. I, JENSEN, N. M, HAVIGHURST, T. C

“…To assess the effectiveness of brief interventions in heavy drinkers by analyzing the outcome data and methodologic quality. (1) Qualitative analysis of…”
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HER-2/neu Overexpression and Response to Oophorectomy Plus Tamoxifen Adjuvant Therapy in Estrogen Receptor-Positive Premenopausal Women With Operable Breast Cancer by LOVE, Richard R, NGUYEN BA DUC, HAVIGHURST, Thomas C, MOHSIN, Syed K, QIAN ZHANG, DEMETS, David L, ALLRED, D. Craig

“…Studies evaluating the relationship of HER-2/neu breast tumor status and response to adjuvant endocrine therapy have reached conflicting conclusions about…”
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Aminoflavone-loaded EGFR-targeted unimolecular micelle nanoparticles exhibit anti-cancer effects in triple negative breast cancer by Brinkman, Ashley M, Chen, Guojun, Wang, Yidan, Hedman, Curtis J, Sherer, Nathan M, Havighurst, Thomas C, Gong, Shaoqin, Xu, Wei

“…Abstract Triple negative breast cancer (TNBC) is an aggressive subtype of breast cancer for which there is no available targeted therapy. TNBC cases contribute…”
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Effect of High-Dose Trivalent vs Standard-Dose Quadrivalent Influenza Vaccine on Mortality or Cardiopulmonary Hospitalization in Patients With High-risk Cardiovascular Disease: A Randomized Clinical Trial by Vardeny, Orly, Kim, KyungMann, Udell, Jacob A, Joseph, Jacob, Desai, Akshay S, Farkouh, Michael E, Hegde, Sheila M, Hernandez, Adrian F, McGeer, Allison, Talbot, H. Keipp, Anand, Inder, Bhatt, Deepak L, Cannon, Christopher P, DeMets, David, Gaziano, J. Michael, Goodman, Shaun G, Nichol, Kristin, Tattersall, Matthew C, Temte, Jonathan L, Wittes, Janet, Yancy, Clyde, Claggett, Brian, Chen, Yi, Mao, Lu, Havighurst, Thomas C, Cooper, Lawton S, Solomon, Scott D

“…IMPORTANCE: Influenza is temporally associated with cardiopulmonary morbidity and mortality among those with cardiovascular disease who may mount a less…”
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Predictors of Willingness to Participate in Window-of-Opportunity Breast Trials by Wisinski, Kari B, Faerber, Adrienne, Wagner, Stephanie, Havighurst, Thomas C, McElroy, Jane A, Kim, Kyungmann, Bailey, Howard H

“…We conducted a pilot survey to evaluate breast cancer patients' willingness to participate in a preoperative chemoprevention (ie, window-of-opportunity) study…”
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Non-melanoma skin cancer event rates in a formalized clinical trial setting: considerations for clinical trial design by Lozar, Taja, Kim, Kyungmann, Havighurst, Thomas C., Wood, Gary S., Kolesar, Jill M., Bailey, Howard H.

“…Here we report clinical risk factors and event rates for the development of new non-melanoma skin cancer (NMSC) in a randomized, double-blind,…”
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Cyclin-mediated G1 Arrest by Celecoxib Differs in Low-versus High-grade Bladder Cancer by GEE, Jason R, BURMEISTER, Corrie B, HAVIGHURST, Thomas C, KIM, Kyungmann

“…Background: Celecoxib and other non-steroidal anti-inflammatory drugs (NSAIDs) are being evaluated in the prevention of bladder and other cancers. Here we…”
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Oophorectomy and Tamoxifen Adjuvant Therapy in Premenopausal Vietnamese and Chinese Women With Operable Breast Cancer by LOVE, Richard R, NGUYEN BA DUC, TRINH LUONG TRAN, TRAN TU QUY, NGUYEN VAN THUY, PHAM NHU THE, TON THAT CAU, NGUYEN DINH TUNG, DANG THANH HUONG, LE MINH QUANG, NGUYEN NGOC HIEN, LE THUONG, ALLRED, D. Craig, SHEN, Tian-Zhen, YE XIN, QIAN ZHANG, HAVIGHURST, Thomas C, YANG, Yonghong Fred, HILLNER, Bruce E, DEMETS, David L, NGUYEN CONG BINH, NGUYEN VAN DINH, NGUYEN NGOC KHA, TRAN VAN THUAN, MOHSIN, Syed K, LE DINH ROANH, HOANG XUAN KHANG

“…In 1992, the Early Breast Cancer Trialists' Collaborative Group reported that a meta-analysis of six randomized trials in European and North American women…”
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Utility of CT Texture Analysis in Differentiating Low-Attenuation Renal Cell Carcinoma From Cysts: A Bi-Institutional Retrospective Study by Kim, Nathan Y, Lubner, Meghan G, Nystrom, Jered T, Swietlik, John F, Abel, E Jason, Havighurst, Thomas C, Silverman, Stuart G, McGahan, John P, Pickhardt, Perry J

“…The purpose of this study was to evaluate the utility of CT texture analysis (CTTA) in differentiating low-attenuation renal cell carcinoma (RCC) from renal…”
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Intratumoral radiation dose heterogeneity augments antitumor immunity in mice and primes responses to checkpoint blockade by Jagodinsky, Justin C, Vera, Jessica M, Jin, Won Jong, Shea, Amanda G, Clark, Paul A, Sriramaneni, Raghava N, Havighurst, Thomas C, Chakravarthy, Ishan, Allawi, Raad H, Kim, KyungMann, Harari, Paul M, Sondel, Paul M, Newton, Michael A, Crittenden, Marka R, Gough, Michael J, Miller, Jessica R, Ong, Irene M, Morris, Zachary S

“…Radiation therapy (RT) activates multiple immunologic effects in the tumor microenvironment (TME), with diverse dose-response relationships observed. We…”
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Effect of Exemestane on Tamoxifen Pharmacokinetics in Postmenopausal Women Treated for Breast Cancer by HUTSON, Paul R, LOVE, Richard R, HAVIGHURST, Thomas C, ROGERS, Eric, CLEARY, James F

“…Purpose: Rodent models of human breast cancer suggest that the combination of the steroidal aromatase inhibitor exemestane with tamoxifen may have additive…”
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Dietary restriction and glucose regulation in aging rhesus monkeys: a follow-up report at 8.5 yr by Gresl, T A, Colman, R J, Roecker, E B, Havighurst, T C, Huang, Z, Allison, D B, Bergman, R N, Kemnitz, J W

“…In a longitudinal study of the effects of moderate (70%) dietary restriction (DR) on aging, plasma glucose and insulin concentrations were measured from…”
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TMPRSS2, a Serine Protease Expressed in the Prostate on the Apical Surface of Luminal Epithelial Cells and Released into Semen in Prostasomes, Is Misregulated in Prostate Cancer Cells by Chen, Ya-Wen, Lee, Ming-Shyue, Lucht, Amanda, Chou, Feng-Pai, Huang, Wei, Havighurst, Thomas C, Kim, KyungMann, Wang, Jehng-Kang, Antalis, Toni M, Johnson, Michael D, Lin, Chen-Yong

“…TMPRSS2, a type II transmembrane serine protease, is highly expressed by the epithelium of the human prostate gland. To explore the regulation and function of…”
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Proproliferative function of adaptor protein GRB10 in prostate carcinoma by Khan, Mohammad Imran, Johani, Ahmed Al, Hamid, Abid, Ateeq, Bushra, Manzar, Nishat, Adhami, Vaqar Mustafa, Lall, Rahul K., Rath, Suvasmita, Sechi, Mario, Siddiqui, Imtiaz Ahmad, Choudhry, Hani, Zamzami, Mazin A., Havighurst, Thomas C., Huang, Wei, Ntambi, James M., Mukhtar, Hasan

“…ABSTRACT Growth factor receptor‐binding protein 10 (GRB10) is a well‐known adaptor protein and a recently identified substrate of the mammalian target of…”
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