Search Results - "HAUSER, Alan R"

The type III secretion system of Pseudomonas aeruginosa : infection by injection by Hauser, Alan R

“…Key Points The Pseudomonas aeruginosa type III secretion system consists of five functional parts: proteins that constitute the secretion machine itself,…”
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Clinical Significance of Microbial Infection and Adaptation in Cystic Fibrosis by Hauser, Alan R, Jain, Manu, Bar-Meir, Maskit, McColley, Susanna A

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Characterization of the core and accessory genomes of Pseudomonas aeruginosa using bioinformatic tools Spine and AGEnt by Ozer, Egon A, Allen, Jonathan P, Hauser, Alan R

“…Pseudomonas aeruginosa is an important opportunistic pathogen responsible for many infections in hospitalized and immunocompromised patients. Previous reports…”
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The Accessory Genome of Pseudomonas aeruginosa by KUNG, Vanderlene L, OZER, Egon A, HAUSER, Alan R

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Genome-wide identification of Acinetobacter baumannii genes necessary for persistence in the lung by Wang, Nengding, Ozer, Egon A, Mandel, Mark J, Hauser, Alan R

“…Acinetobacter baumannii is a Gram-negative bacterium that causes diseases such as pneumonia, bacteremia, and soft tissue infections in hospitalized patients…”
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Systemic infection facilitates transmission of Pseudomonas aeruginosa in mice by Bachta, Kelly E. R., Allen, Jonathan P., Cheung, Bettina H., Chiu, Cheng-Hsun, Hauser, Alan R.

“…Health care-associated infections such as Pseudomonas aeruginosa bacteremia pose a major clinical risk for hospitalized patients. However, these systemic…”
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Clinical outcomes of type III Pseudomonas aeruginosa bacteremia by El-Solh, Ali A, Hattemer, Angela, Hauser, Alan R, Alhajhusain, Ahmad, Vora, Hardik

“…BACKGROUND:Pseudomonas aeruginosa bacteremia is a serious and life-threatening infection associated with high mortality. Among the multitude of virulence…”
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Pseudomonas aeruginosa Cytotoxin ExoU Is Injected into Phagocytic Cells during Acute Pneumonia by Diaz, Maureen H, Hauser, Alan R

“…ExoU, a cytotoxin translocated into host cells via the type III secretion system of Pseudomonas aeruginosa, is associated with increased mortality and disease…”
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Genomic surveillance for multidrug-resistant or hypervirulent Klebsiella pneumoniae among United States bloodstream isolates by Kochan, Travis J, Nozick, Sophia H, Medernach, Rachel L, Cheung, Bettina H, Gatesy, Samuel W M, Lebrun-Corbin, Marine, Mitra, Sumitra D, Khalatyan, Natalia, Krapp, Fiorella, Qi, Chao, Ozer, Egon A, Hauser, Alan R

“…Klebsiella pneumoniae strains have been divided into two major categories: classical K. pneumoniae, which are frequently multidrug-resistant and cause…”
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The Role of ExoS in Dissemination of Pseudomonas aeruginosa during Pneumonia by Rangel, Stephanie M, Diaz, Maureen H, Knoten, Claire A, Zhang, Angelica, Hauser, Alan R

“…Hospital-acquired pneumonia is associated with high rates of morbidity and mortality, and dissemination to the bloodstream is a recognized risk factor for…”
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Relative Contributions of Pseudomonas aeruginosa ExoU, ExoS, and ExoT to Virulence in the Lung by SHAVER, Ciara M, HAUSER, Alan R

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The global population stru cture of Lacticaseibacillus rhamnosus and its application to an investigation of a rare case of infective endocarditis by Santoiemma, Phillip P, Cohn, Susan E, Gatesy, Samuel W M, Hauser, Alan R, Agrawal, Saaket, Theodorou, Maria E, Bachta, Kelly E R, Ozer, Egon A

“…Lacticaseibacillus (formerly Lactobacillus) rhamnosus is widely used in probiotics or food supplements to promote microbiome health and may also be part of the…”
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Type III secretion of ExoU is critical during early Pseudomonas aeruginosa pneumonia by Howell, Heather A, Logan, Latania K, Hauser, Alan R

“…The Pseudomonas aeruginosa type III secretion system has been associated with poor outcomes in both animal models and human patients. Despite a large number of…”
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A Review of the Clinical Pharmacokinetics of Polymyxin B by Avedissian, Sean N, Liu, Jiajun, Rhodes, Nathaniel J, Lee, Andrew, Pais, Gwendolyn M, Hauser, Alan R, Scheetz, Marc H

“…Polymyxin B remains an antibiotic of last resort because of its toxicities. Although newer therapies are becoming available, it is anticipated that resistance…”
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Klebsiella pneumoniae clinical isolates with features of both multidrug-resistance and hypervirulence have unexpectedly low virulence by Kochan, Travis J., Nozick, Sophia H., Valdes, Aliki, Mitra, Sumitra D., Cheung, Bettina H., Lebrun-Corbin, Marine, Medernach, Rachel L., Vessely, Madeleine B., Mills, Jori O., Axline, Christopher M. R., Nelson, Julia A., VanGosen, Ethan M., Ward, Timothy J., Ozer, Egon A., van Duin, David, Chen, Liang, Kreiswirth, Barry N., Long, S. Wesley, Musser, James M., Bulman, Zackery P., Wunderink, Richard G., Hauser, Alan R.

“…Klebsiella pneumoniae has been classified into two types, classical K. pneumoniae (cKP) and hypervirulent K. pneumoniae (hvKP). cKP isolates are highly diverse…”
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Phosphatidylinositol 4,5-Bisphosphate Is a Novel Coactivator of the Pseudomonas aeruginosa Cytotoxin ExoU by Tyson, Gregory H, Hauser, Alan R

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Hypercapnia impairs lung neutrophil function and increases mortality in murine pseudomonas pneumonia by Gates, Khalilah L, Howell, Heather A, Nair, Aisha, Vohwinkel, Christine U, Welch, Lynn C, Beitel, Greg J, Hauser, Alan R, Sznajder, Jacob I, Sporn, Peter H S

“…Hypercapnia, an elevation of the level of carbon dioxide (CO2) in blood and tissues, is a marker of poor prognosis in chronic obstructive pulmonary disease and…”
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The three NADH dehydrogenases of Pseudomonas aeruginosa: Their roles in energy metabolism and links to virulence by Hreha, Teri N, Foreman, Sara, Duran-Pinedo, Ana, Morris, Andrew R, Diaz-Rodriguez, Patricia, Jones, J Andrew, Ferrara, Kristina, Bourges, Anais, Rodriguez, Lauren, Koffas, Mattheos A G, Hahn, Mariah, Hauser, Alan R, Barquera, Blanca

“…Pseudomonas aeruginosa is a ubiquitous opportunistic pathogen which relies on a highly adaptable metabolism to achieve broad pathogenesis. In one example of…”
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Genomics of Aminoglycoside Resistance in Pseudomonas aeruginosa Bloodstream Infections at a United States Academic Hospital by Atassi, Giancarlo, Medernach, Rachel, Scheetz, Marc, Nozick, Sophia, Rhodes, Nathaniel J, Murphy-Belcaster, Megan, Murphy, Katherine R, Alisoltani, Arghavan, Ozer, Egon A, Hauser, Alan R

“…Pseudomonas aeruginosa frequently becomes resistant to aminoglycosides by the acquisition of aminoglycoside modifying enzyme (AME) genes and the occurrence of…”
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Genome-wide screens reveal shared and strain-specific genes that facilitate enteric colonization by Klebsiella pneumoniae by Cheung, Bettina H, Alisoltani, Arghavan, Kochan, Travis J, Lebrun-Corbin, Marine, Nozick, Sophia H, Axline, Christopher M R, Bachta, Kelly E R, Ozer, Egon A, Hauser, Alan R

“…Gastrointestinal (GI) colonization by is a risk factor for subsequent infection as well as transmission to other patients. Additionally, colonization is…”
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