Search Results - "HAUKAAS, Svein A"

A Switch from E-Cadherin to N-Cadherin Expression Indicates Epithelial to Mesenchymal Transition and Is of Strong and Independent Importance for the Progress of Prostate Cancer by GRAVDAL, Karsten, HALVORSEN, Ole J, HAUKAAS, Svein A, AKSLEN, Lars A

“…Purpose: Cell adhesion molecules are of crucial importance in cancer invasion and metastasis. Epithelial to mesenchymal transition, characterized by reduced…”
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EZH2 Expression Is Associated With High Proliferation Rate and Aggressive Tumor Subgroups in Cutaneous Melanoma and Cancers of the Endometrium, Prostate, and Breast by BACHMANN, Ingeborg M, HALVORSEN, Ole J, COLLETT, Karin, STEFANSSON, Ingunn M, STRAUME, Oddbjørn, HAUKAAS, Svein A, SALVESEN, Helga B, OTTE, Arie P, AKSLEN, Lars A

“…EZH2 is a member of the polycomb group of genes and important in cell cycle regulation. Increased expression of EZH2 has been associated previously with…”
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Microvascular proliferation is associated with high tumour blood flow by mpMRI and disease progression in primary prostate cancer by Børretzen, Astrid, Reisæter, Lars A. R., Ringheim, Anders, Gravdal, Karsten, Haukaas, Svein A., Fasmer, Kristine E., Haldorsen, Ingfrid H. S., Beisland, Christian, Akslen, Lars A., Halvorsen, Ole J.

“…Active angiogenesis may be assessed by immunohistochemistry using Nestin, a marker of newly formed vessels, combined with Ki67 for proliferating cells. Here,…”
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Genome-wide profiling of histone h3 lysine 4 and lysine 27 trimethylation reveals an epigenetic signature in prostate carcinogenesis by Ke, Xi-Song, Qu, Yi, Rostad, Kari, Li, Wen-Cheng, Lin, Biaoyang, Halvorsen, Ole Johan, Haukaas, Svein A, Jonassen, Inge, Petersen, Kjell, Goldfinger, Naomi, Rotter, Varda, Akslen, Lars A, Oyan, Anne M, Kalland, Karl-Henning

“…Increasing evidence implicates the critical roles of epigenetic regulation in cancer. Very recent reports indicate that global gene silencing in cancer is…”
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Bone marrow-derived Gr1+ cells can generate a metastasis-resistant microenvironment via induced secretion of thrombospondin-1 by Catena, Raúl, Bhattacharya, Nandita, El Rayes, Tina, Wang, Suming, Choi, Hyejin, Gao, Dingcheng, Ryu, Seongho, Joshi, Natasha, Bielenberg, Diane, Lee, Sharrell B, Haukaas, Svein A, Gravdal, Karsten, Halvorsen, Ole J, Akslen, Lars A, Watnick, Randolph S, Mittal, Vivek

“…Metastatic tumors have been shown to establish permissive microenvironments for metastases via recruitment of bone marrow-derived cells. Here, we show that…”
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FOXC2 expression and epithelial–mesenchymal phenotypes are associated with castration resistance, metastasis and survival in prostate cancer by Børretzen, Astrid, Gravdal, Karsten, Haukaas, Svein A, Beisland, Christian, Akslen, Lars A, Halvorsen, Ole J

“…Epithelial–mesenchymal transition (EMT) is important for tumour cell invasion and metastasis and is a feature of aggressive carcinomas. EMT is characterised by…”
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Proliferation of Immature Tumor Vessels Is a Novel Marker of Clinical Progression in Prostate Cancer by GRAUDAL, Karsten, HALVORSEN, Ole J, HAUKAAS, Svein A, AKSLEN, Lars A

“…Nestin (neuroepithelial stem cell protein) is expressed in immature endothelial cells, and we here introduce coexpression of Nestin and Ki-67 as a novel…”
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The epithelial–mesenchymal transition regulators Twist, Slug, and Snail are associated with aggressive tumour features and poor outcome in prostate cancer patients by Børretzen, Astrid, Gravdal, Karsten, Haukaas, Svein A, Mannelqvist, Monica, Beisland, Christian, Akslen, Lars A, Halvorsen, Ole J

“…The prognostic importance of transcription factors promoting epithelial–mesenchymal transition (EMT) and angiogenesis has not been well explored in prostate…”
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Prosaposin inhibits tumor metastasis via paracrine and endocrine stimulation of stromal p53 and Tsp-1 by Kang, Soo-Young, Halvorsen, Ole J, Gravdal, Karsten, Bhattacharya, Nandita, Lee, Jung Min, Liu, Nathan W, Johnston, Brian T, Johnston, Adam B, Haukaas, Svein A, Aamodt, Kristie, Yoo, Sun, Akslen, Lars A, Watnick, Randolph S

“…Metastatic tumors can prepare a distant site for colonization via the secretion of factors that act in a systemic manner. We hypothesized that non- or weakly…”
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The expression of thrombospondin-1 and p53 in clear cell renal cell carcinoma: its relationship to angiogenesis, cell proliferation and cancer specific survival by Zubac, Dragomir P, Bostad, Leif, Kihl, Björn, Seidal, Tomas, Wentzel-Larsen, Tore, Haukaas, Svein A

“…We evaluated possible associations among thrombospondin-1, p53 expression, microvessel density, cell proliferation index, nuclear grade, tumor stage and…”
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Combined Loss of PTEN and p27 Expression Is Associated with Tumor Cell Proliferation by Ki-67 and Increased Risk of Recurrent Disease in Localized Prostate Cancer by HALVORSEN, Ole J, HAUKAAS, Svein A, AKSLEN, Lars A

“…Purpose: Recent experimental work indicates a major role for PTEN and p27 in prostate cancer. The combined loss of PTEN and p27 was found to strongly increase…”
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Expression of bFGF/FGFR-1 and vascular proliferation related to clinicopathologic features and tumor progress in localized prostate cancer by GRAVDAL, Karsten, HALVORSEN, Ole J, HAUKAAS, Svein A, AKSLEN, Lar A

“…Microvessel density (MVD) has been associated with progression of prostate cancer. Although basic fibroblast growth factor (bFGF) is a known endothelial…”
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The prognostic relevance of interactions between venous invasion, lymph node involvement and distant metastases in renal cell carcinoma after radical nephrectomy by Zubac, Dragomir P, Bostad, Leif, Seidal, Tomas, Wentzel-Larsen, Tore, Haukaas, Svein A

“…To investigate a possible prognostic significance of interactions between lymph node invasion (LNI), synchronous distant metastases (SDM), and venous invasion…”
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A positive real‐time elastography is an independent marker for detection of high‐risk prostate cancers in the primary biopsy setting by Nygård, Yngve, Haukaas, Svein A., Halvorsen, Ole J., Gravdal, Karsten, Frugård, Jannicke, Akslen, Lars A., Beisland, Christian

“…Objective To evaluate the performance of real‐time elastography (RTE) in an initial biopsy setting. Patients and Methods In the period from February 2011 to…”
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A positive Real-Time Elastography (RTE) combined with a Prostate Cancer Gene 3 (PCA3) score above 35 convey a high probability of intermediate- or high-risk prostate cancer in patient admitted for primary prostate biopsy by Nygård, Yngve, Haukaas, Svein A, Halvorsen, Ole J, Gravdal, Karsten, Frugård, Jannicke, Akslen, Lars A, Beisland, Christian

“…The standard of care in patients with suspected prostate cancer (PCa) is systematic prostate biopsies. This approach leads to unnecessary biopsies in patients…”
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TMPRSS2:ERG fusion transcripts in urine from prostate cancer patients correlate with a less favorable prognosis by ROSTAD, KARI, HELLWINKEL, OLAF J.C, HAUKAAS, SVEIN A, HALVORSEN, OLE J, ØYAN, ANNE M, HAESE, ALEXANDER, BUDÄUS, LARS, ALBRECHT, HEIKO, AKSLEN, LARS A, SCHLOMM, THORSTEN, KALLAND, KARL-HENNING

“…The transcription factor ERG is highly upregulated in the majority of prostate cancers due to chromosomal fusion of the androgen responsive promoter of TMPRSS2…”
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Prostate cancer antigen-3 (PCA3) and PCA3-based nomograms in the diagnosis of prostate cancer: an external validation of Hansen's nomogram on a Norwegian cohort by Nygård, Yngve, Haukaas, Svein A, Eide, Geir Egil, Halvorsen, Ole J, Gravdal, Karsten, Frugård, Jannicke, Akslen, Lars A, Beisland, Christian

“…The aim of this study was to test the ability of prostate cancer antigen-3 (PCA3) and Hansen's PCA3-based nomogram to predict prostate cancer (PCa) probability…”
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Combination of real-time elastography and urine prostate cancer gene 3 (PCA3) detects more than 97% of significant prostate cancers by Nygård, Yngve, Haukaas, Svein A, Waage, Jo E R, Halvorsen, Ole J, Gravdal, Karsten, Frugård, Jannicke, Akslen, Lars A, Beisland, Christian

“…The prostate cancer gene 3 (PCA3) score in urine is a promising biomarker for prostate cancer. Real-time elastography (RTE) is a well-documented ultrasound…”
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Prognostic importance of glomeruloid microvascular proliferation indicates an aggressive angiogenic phenotype in human cancers by STRAUME, Oddbjørn, CHAPPUIS, Pierre O, SALVESEN, Helga B, HALVORSEN, Ole J, HAUKAAS, Svein A, GOFFIN, John R, BEGIN, Louis R, FOULKES, William D, AKSLEN, Lars A

“…We evaluated the presence of glomeruloid microvascular proliferations (GMPs) in 723 patients with melanomas, breast, endometrial, or prostate cancer. Presence…”
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Is preoperative serum prostate‐specific antigen level significantly related to clinical recurrence after radical retropubic prostatectomy for localized prostate cancer? by HAUKAAS, SVEIN A., HALVORSEN, OLE J., DAEHLIN, LARS, HOSTMARK, JENS, AKSLEN, LARS A.

“…OBJECTIVE To evaluate the influence of preoperative serum prostate‐specific antigen (PSA) level and other clinicopathological variables on the probability of…”
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