Search Results - "HAUGER, R"

PTSD in women is associated with a block in conversion of progesterone to the GABAergic neurosteroids allopregnanolone and pregnanolone measured in plasma by Pineles, S.L., Nillni, Y.I., Pinna, G., Irvine, J., Webb, A., Arditte Hall, K.A., Hauger, R., Miller, M.W., Resick, P.A., Orr, S.P., Rasmusson, A.M.

“…•There is a PTSD-related block in ALLO synthesis at 3α-HSD.•The present study confirmed this finding in plasma.•Ability to measure ALLO in plasma is important…”
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The role of PKC signaling in CRF-induced modulation of startle by Toth, M., Gresack, J. E., Hauger, R. L., Halberstadt, A. L., Risbrough, V. B.

“…Rationale Hypersignaling of corticotropin releasing factor (CRF) has been implicated in stress disorders; however, many of its downstream mechanisms of action…”
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Working Memory Is More Sensitive Than Declarative Memory to the Acute Effects of Corticosteroids: A Dose-Response Study in Humans by Lupien, Sonia J, Gillin, Christian J, Hauger, Richard L

“…The effects of various doses (40 μg/kg/hr, 300 μg/kg/hr, 600 μg/kg/hr or placebo) of hydrocortisone on tasks assessing working and declarative memory function…”
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Evidence that a single nucleotide polymorphism in the promoter of the G protein receptor kinase 3 gene is associated with bipolar disorder by BARRETT, T. B, HAUGER, R. L, KENNEDY, J. L, SADOVNICK, A. D, REMICK, R. A, KECK, P. E, MCELROY, S. L, ALEXANDER, M, SHAW, S. H

“…In a genome-wide linkage survey, we have previously shown evidence suggesting that the chromosome 22q12 region contains a susceptibility locus for bipolar…”
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Stress-induced declarative memory impairment in healthy elderly subjects : Relationship to cortisol reactivity by LUPIEN, S. J, GAUDREAU, S, TCHITEYA, B. M, MAHEU, F, SHARMA, S, NAIR, N. P. V, HAUGER, R. L, MCEWEN, B. S, MEANEY, M. J

“…A group of 14 healthy elderly subjects was submitted to a nonstressful (attentional task) and a stressful (public speaking task) condition. Declarative…”
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Plasma cortisol and neuropeptide Y in female victims of intimate partner violence by Seedat, S., Stein, M.B., Kennedy, C.M., Hauger, R.L.

“…Background: The experience of intimate partner violence (physical and sexual violence) has been linked to psychiatric disorders such as posttraumatic stress…”
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Plasma neuropeptide-Y concentrations in humans exposed to military survival training by Morgan, Charles A, Wang, Sheila, Southwick, Steven M, Rasmusson, Ann, Hazlett, Gary, Hauger, Richard L, Charney, Dennis S

“…Background: Neuropeptide-Y (NPY) is present in extensive neuronal systems of the brain and is present in high concentrations in cell bodies and terminals in…”
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Testosterone modifies the effect of APOE genotype on hippocampal volume in middle-aged men by PANIZZON, M. S, HAUGER, R, JACOBSON, K. C, LYONS, M. J, MENDOZA, S. P, NEALE, M. C, PROM-WORMLEY, E. C, SEIDMAN, L. J, TSUANG, M. T, XIAN, H, KREMEN, W. S, DALE, A. M, EAVES, L. J, EYLER, L. T, FISCHL, B, FENNEMA-NOTESTINE, C, FRANZ, C. E, GRANT, M. D, JAK, A. J

“…The APOE epsilon4 allele is an established risk factor for Alzheimer disease (AD), yet findings are mixed for how early its effects are manifest. One reason…”
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Low baseline and yohimbine-stimulated plasma neuropeptide Y (NPY) levels in combat-related PTSD by Rasmusson, Ann M, Hauger, Richard L, Morgan, Charles A, Bremner, J.Douglas, Charney, Dennis S, Southwick, Steven M

“…Background: Consistent with many studies demonstrating enhanced reactivity of the sympathetic nervous system in posttraumatic stress disorder (PTSD), the…”
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Circadian phase in adults of contrasting ages by Kripke, D F, Youngstedt, S D, Elliott, J A, Tuunainen, A, Rex, K M, Hauger, R L, Marler, M R

“…There is evidence that aging may impair phase-shifting responses to light synchronizers, which could lead to disturbed or malsynchronized circadian rhythms. To…”
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Identifying a series of candidate genes for mania and psychosis: a convergent functional genomics approach by NICULESCU, ALEXANDER B., III, SEGAL, DAVID S, KUCZENSKI, RONALD, BARRETT, THOMAS, HAUGER, RICHARD L, KELSOE, JOHN R

“…1 Department of Psychiatry, School of Medicine, University of California, San Diego 2 Department of Psychiatry, San Diego Veterans Affairs Healthcare System,…”
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Effects of sleep and sleep deprivation on interleukin-6, growth hormone, cortisol, and melatonin levels in humans by REDWINE, Laura, HAUGER, Richard L, GILLIN, J. Christian, IRWIN, Michael

“…The objective of this study was to evaluate the effects of nocturnal sleep, partial night sleep deprivation, and sleep stages on circulating concentrations of…”
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Central serotonin activity and aggression: inverse relationship with prolactin response to d-fenfluramine, but not CSF 5-HIAA concentration, in human subjects by COCCARO, E. F, KAVOUSSI, R. J, COOPER, T. B, HAUGER, R. L

“…OBJECTIVE: This study compared the nature and magnitude of the relationship between aggression and CSF 5-hydroxyindoleacetic acid (5- HIAA) concentration with…”
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A multivariate twin study of hippocampal volume, self‐esteem and well‐being in middle‐aged men by Kubarych, T. S., Prom‐Wormley, E. C., Franz, C. E., Panizzon, M. S., Dale, A. M., Fischl, B., Eyler, L. T., Fennema‐Notestine, C., Grant, M. D., Hauger, R. L., Hellhammer, D. H., Jak, A. J., Jernigan, T. L., Lupien, S. J., Lyons, M. J., Mendoza, S. P., Neale, M. C., Seidman, L. J., Tsuang, M. T., Kremen, W. S.

“…Self‐esteem and well‐being are important for successful aging, and some evidence suggests that self‐esteem and well‐being are associated with hippocampal…”
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Cortisol levels during human aging predict hippocampal atrophy and memory deficits by Lupien, Sonia J, de Leon, Mony, de Santi, Susan, Convit, Antonio, Tarshish, Chaim, Nair, N. P. V, Thakur, Mira, McEwen, Bruce S, Hauger, Richard L, Meaney, Michael J

“…Elevated glucocorticoid levels produce hippocampal dysfunction and correlate with individual deficits in spatial learning in aged rats. Previously we related…”
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Serotonin function and antiaggressive response to fluoxetine : A pilot study by COCCARO, E. F, KAVOUSSI, R. J, HAUGER, R. L

“…The reported inverse relationship between indices of central serotonin (5-HT) function and indices of impulsive aggression in human subjects suggests the…”
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Regulation of Corticotropin‐Releasing Factor Receptor Function in Human Y‐79 Retinoblastoma Cells: Rapid and Reversible Homologous Desensitization but Prolonged Recovery by Hauger, R. L., Dautzenberg, F. M., Flaccus, A., Liepold, T., Spiess, J.

“…: Homologous receptor desensitization is an important regulatory response to continuous activation by agonist that involves the uncoupling of a receptor from…”
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Relationship of prolactin response to d-fenfluramine to behavioral and questionnaire assessments of aggression in personality-disordered men by Coccaro, Emil F., Berman, Mitchell E., Kavoussi, Richard J., Hauger, Richard L.

“…Prolactin (PRL) responses to acute challenge with the serotonin (5-HT) releaser/uptake inhibitor, d-fenfluramine (PRL[d-FEN]), were correlated with three…”
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Longitudinal study of basal cortisol levels in healthy elderly subjects: Evidence for subgroups by Lupien, Sonia, Lecours, AndréRoch, Schwartz, George, Sharma, Shakti, Hauger, Richard L., Meaney, Michael J., Nair, N.P.V.

“…A group of 51 healthy elderly volunteer subjects participated in a 3- to 6-year longitudinal study of basal cortisol levels. Once per year basal cortisol…”
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Role of corticotropin releasing factor (CRF) receptors 1 and 2 in CRF-potentiated acoustic startle in mice by RISBROUGH, Victoria B, HAUGER, Richard L, PELLEYMOUNTER, Mary Ann, GEYER, Mark A

“…Hypersecretion of corticotropin releasing factor (CRF) has been implicated in both severe anxiety disorders and major depression. Although the role of the CRF1…”
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