Search Results - "HAUGEN, Bryan R"

Progress in molecular-based management of differentiated thyroid cancer by Xing, Mingzhao, Prof, Haugen, Bryan R, Prof, Schlumberger, Martin, Prof

“…Summary Substantial developments have occurred in the past 5–10 years in clinical translational research of thyroid cancer. Diagnostic molecular markers, such…”
Get full text

Genetic Analysis of 779 Advanced Differentiated and Anaplastic Thyroid Cancers by Pozdeyev, Nikita, Gay, Laurie M, Sokol, Ethan S, Hartmaier, Ryan, Deaver, Kelsi E, Davis, Stephanie, French, Jena D, Borre, Pierre Vanden, LaBarbera, Daniel V, Tan, Aik-Choon, Schweppe, Rebecca E, Fishbein, Lauren, Ross, Jeffrey S, Haugen, Bryan R, Bowles, Daniel W

“…To define the genetic landscape of advanced differentiated and anaplastic thyroid cancer (ATC) and identify genetic alterations of potential diagnostic,…”
Get full text

Drugs that suppress TSH or cause central hypothyroidism by Haugen, Bryan R., MD

“…Many different drugs affect thyroid function. Most of these drugs act at the level of the thyroid in patients with normal thyroid function, or at the level of…”
Get full text

Tailoring the approach to radioactive iodine treatment in thyroid cancer by Mayson, Sarah E, Chan, Christine M, Haugen, Bryan R

“…The treatment of differentiated thyroid cancer continues to move away from a ‘one size fits all’ approach to a process of tailored therapeutic decision-making…”
Get full text

Comprehensive Genetic Characterization of Human Thyroid Cancer Cell Lines: A Validated Panel for Preclinical Studies by Landa, Iñigo, Pozdeyev, Nikita, Korch, Christopher, Marlow, Laura A, Smallridge, Robert C, Copland, John A, Henderson, Ying C, Lai, Stephen Y, Clayman, Gary L, Onoda, Naoyoshi, Tan, Aik Choon, Garcia-Rendueles, Maria E R, Knauf, Jeffrey A, Haugen, Bryan R, Fagin, James A, Schweppe, Rebecca E

“…Thyroid cancer cell lines are valuable models but have been neglected in pancancer genomic studies. Moreover, their misidentification has been a significant…”
Get full text

Molecular Testing for Mutations in Improving the Fine-Needle Aspiration Diagnosis of Thyroid Nodules by Nikiforov, Yuri E., Steward, David L., Robinson-Smith, Toni M., Haugen, Bryan R., Klopper, Joshua P., Zhu, Zhaowen, Fagin, James A., Falciglia, Mercedes, Weber, Katherine, Nikiforova, Marina N.

“…Context: Thyroid nodules are common in adults, but only a small fraction of them are malignant. Fine-needle aspiration (FNA) with cytological evaluation is the…”
Get full text

2015 American Thyroid Association Management Guidelines for Adult Patients with Thyroid Nodules and Differentiated Thyroid Cancer: What is new and what has changed? by Haugen, Bryan R.

“…Thyroid nodules are very common, and thyroid cancer is currently the fifth leading cancer diagnosis in women. The American Thyroid Association has led the…”
Get full text

Preclinical Models of Follicular Cell-Derived Thyroid Cancer: An Overview from Cancer Cell Lines to Mouse Models by Jeon, Min Ji, Haugen, Bryan R

“…The overall prognosis of thyroid cancer is excellent, but some patients have grossly invasive disease and distant metastases with limited responses to systemic…”
Get full text

Computer-Assisted Levothyroxine Dose Selection for the Treatment of Postoperative Hypothyroidism by Barrio, Martin, Raeburn, Christopher D, McIntyre, , Jr, Robert, Albuja-Cruz, Maria, Haugen, Bryan R, Pozdeyev, Nikita

“…Thyroid hormone replacement with levothyroxine (LT4) is a recommended treatment for patients undergoing thyroidectomy. The starting LT4 dose is frequently…”
Get more information

Molecular Diagnostic Evaluation of Thyroid Nodules by Mayson, Sarah E., MD, Haugen, Bryan R., MD

“…The historical management approach for many patients with indeterminate thyroid nodule fine needle aspiration cytology is a diagnostic lobectomy or…”
Get full text

Long-Term Outcomes Following Therapy in Differentiated Thyroid Carcinoma: NTCTCS Registry Analysis 1987–2012 by Carhill, Aubrey A, Litofsky, Danielle R, Ross, Douglas S, Jonklaas, Jacqueline, Cooper, David S, Brierley, James D, Ladenson, Paul W, Ain, Kenneth B, Fein, Henry G, Haugen, Bryan R, Magner, James, Skarulis, Monica C, Steward, David L, Xing, Mingxhao, Maxon, Harry R, Sherman, Steven I

“…Context: Initial treatments for patients with differentiated thyroid cancer are supported primarily by single-institution, retrospective studies, with limited…”
Get full text

Deoxyribonucleic Acid Profiling Analysis of 40 Human Thyroid Cancer Cell Lines Reveals Cross-Contamination Resulting in Cell Line Redundancy and Misidentification by Schweppe, Rebecca E., Klopper, Joshua P., Korch, Christopher, Pugazhenthi, Umarani, Benezra, Miriam, Knauf, Jeffrey A., Fagin, James A., Marlow, Laura A., Copland, John A., Smallridge, Robert C., Haugen, Bryan R.

“…Context: Cell lines derived from human cancers provide critical tools to study disease mechanisms and develop novel therapies. Recent reports indicate that up…”
Get full text

A Prospective Assessment Defining the Limitations of Thyroid Nodule Pathologic Evaluation by CIBAS, Edmund S, BALOCH, Zubair W, LANMAN, Richard B, MANDEL, Susan J, SINDY, Nicole, STEWARD, David L, ZEIGER, Martha A, HAUGEN, Bryan R, ALEXANDER, Erik K, FELLEGARA, Giovanni, LIVOLSI, Virginia A, RAAB, Stephen S, ROSAI, Juan, DIGGANS, James, FRIEDMAN, Lyssa, KENNEDY, Giulia C, KLOOS, Richard T

“…Clinical management of thyroid neoplasms is based on light microscopic diagnosis, but its accuracy and precision are poorly defined. To assess inter- and…”
Get full text

Leveraging the immune system to treat advanced thyroid cancers by French, Jena D, PhD, Bible, Keith, Prof, Spitzweg, Christine, Prof, Haugen, Bryan R, Prof, Ryder, Mabel, Dr

“…Summary Inflammation has long been associated with the thyroid and with thyroid cancers, raising seminal questions about the role of the immune system in the…”
Get full text

Prognosis of differentiated thyroid cancer in relation to serum thyrotropin and thyroglobulin antibody status at time of diagnosis by McLeod, Donald S A, Cooper, David S, Ladenson, Paul W, Ain, Kenneth B, Brierley, James D, Fein, Henry G, Haugen, Bryan R, Jonklaas, Jacqueline, Magner, James, Ross, Douglas S, Skarulis, Monica C, Steward, David L, Maxon, Harry R, Sherman, Steven I

“…Serum thyrotropin (TSH) concentration and thyroid autoimmunity may be of prognostic importance in differentiated thyroid cancer (DTC). Preoperative serum TSH…”
Get more information

Thioredoxin interacting protein (TXNIP) is a novel tumor suppressor in thyroid cancer by Morrison, Jennifer A, Pike, Laura A, Sams, Sharon B, Sharma, Vibha, Zhou, Qiong, Severson, Jill J, Tan, Aik-Choon, Wood, William M, Haugen, Bryan R

“…Thyroid cancer is the most common endocrine malignancy, and many patients with metastatic differentiated thyroid cancer (DTC), poorly differentiated thyroid…”
Get full text

Targeting the NF-κB Pathway as a Combination Therapy for Advanced Thyroid Cancer by Pozdeyev, Nikita, Berlinberg, Adam, Zhou, Qiong, Wuensch, Kelsey, Shibata, Hiroyuki, Wood, William M, Haugen, Bryan R

“…NF-κB signaling plays an important role in tumor cell proliferation, cell survival, angiogenesis, invasion, metastasis and drug/radiation resistance…”
Get full text

Recurrence after treatment of micropapillary thyroid cancer by Ross, Douglas S, Litofsky, Danielle, Ain, Kenneth B, Bigos, Thomas, Brierley, James D, Cooper, David S, Haugen, Bryan R, Jonklaas, Jacqueline, Ladenson, Paul W, Magner, James, Robbins, Jacob, Skarulis, Monica C, Steward, David L, Maxon, Harry R, Sherman, Steven I

“…Despite very low mortality associated with micropapillary thyroid cancer, locoregional recurrence is common and controversy exists regarding optimal surgical…”
Get more information

Tumor‐specific changes in mtDNA content in human cancer by Mambo, Elizabeth, Chatterjee, Aditi, Xing, Mingzhao, Tallini, Giovanni, Haugen, Bryan R., Yeung, Sai‐Ching J., Sukumar, Saraswati, Sidransky, David

“…Mitochondrial DNA (mtDNA) alterations are associated with various cancer types, suggesting that the mitochondrial genome may be a critical contributing factor…”
Get full text

A “safe and effective” protocol for management of post-thyroidectomy hypocalcemia by Albuja-Cruz, Maria B., M.D, Pozdeyev, Nikita, M.D., Ph.D, Robbins, Steven, M.D, Chandramouli, Radhika, B.S, Raeburn, Christopher D., M.D, Klopper, Joshua, M.D, Haugen, Bryan R., M.D, McIntyre, Robert, M.D

“…Abstract Background This study evaluates the outcomes of a protocol to manage hypocalcemia after thyroidectomy (TTX). Methods A review of prospectively…”
Get full text