Search Results - "HAUGEN, Aage"

KIF5B-RET fusions in lung adenocarcinoma by Kohno, Takashi, Ichikawa, Hitoshi, Totoki, Yasushi, Yasuda, Kazuki, Hiramoto, Masaki, Nammo, Takao, Sakamoto, Hiromi, Tsuta, Koji, Furuta, Koh, Shimada, Yoko, Iwakawa, Reika, Ogiwara, Hideaki, Oike, Takahiro, Enari, Masato, Schetter, Aaron J, Okayama, Hirokazu, Haugen, Aage, Skaug, Vidar, Chiku, Suenori, Yamanaka, Itaru, Arai, Yasuhito, Watanabe, Shun-ichi, Sekine, Ikuo, Ogawa, Seishi, Harris, Curtis C, Tsuda, Hitoshi, Yoshida, Teruhiko, Yokota, Jun, Shibata, Tatsuhiro

“…The authors report a new type of genetic alteration in lung adenocarcinoma. Fusions of KIF5B with RET kinase are found in 1–2% of lung cancer patients,…”
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An Integrated Prognostic Classifier for Stage I Lung Adenocarcinoma Based on mRNA, microRNA, and DNA Methylation Biomarkers by Robles, Ana I, Arai, Eri, Mathé, Ewy A, Okayama, Hirokazu, Schetter, Aaron J, Brown, Derek, Petersen, David, Bowman, Elise D, Noro, Rintaro, Welsh, Judith A, Edelman, Daniel C, Stevenson, Holly S, Wang, Yonghong, Tsuchiya, Naoto, Kohno, Takashi, Skaug, Vidar, Mollerup, Steen, Haugen, Aage, Meltzer, Paul S, Yokota, Jun, Kanai, Yae, Harris, Curtis C

“…Up to 30% stage I lung cancer patients suffer recurrence within 5 years of curative surgery. We sought to improve existing protein-coding gene and microRNA…”
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Polymorphisms of DNA repair genes and risk of non-small cell lung cancer by Zienolddiny, Shanbeh, Campa, Daniele, Lind, Helge, Ryberg, David, Skaug, Vidar, Stangeland, Lodve, Phillips, David H., Canzian, Federico, Haugen, Aage

“…Lung cancer is a leading cause of cancer mortality with an inter-individual difference in susceptibility to the disease. The inheritance of low-efficiency…”
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Stable serum miRNA profiles as potential tool for non-invasive lung cancer diagnosis by Keller, Andreas, Leidinger, Petra, Gislefoss, Randi, Haugen, Aage, Langseth, Hilde, Staehler, Peer, Lenhof, Hans-Peter, Meese, Eckart

“…Circulating microRNAs in human serum have increasingly been recognized as stable markers for cancer detection. However, there is still a lack of miRNome wide…”
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Importance of CYP1A1 and CYP1B1 in bioactivation of benzo[ a]pyrene in human lung cell lines by Uppstad, Heidi, Øvrebø, Steinar, Haugen, Aage, Mollerup, Steen

“…Polycyclic aromatic hydrocarbons are ubiquitous environmental pollutants classified as carcinogens in humans and rodents. The cytochromes P4501A1 and 1B1 have…”
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Bulky DNA adducts, microRNA profiles, and lipid biomarkers in Norwegian tunnel finishing workers occupationally exposed to diesel exhaust by Rynning, Iselin, Arlt, Volker M, Vrbova, Kristyna, Neča, Jiří, Rossner Jr, Pavel, Klema, Jiri, Ulvestad, Bente, Petersen, Elisabeth, Skare, Øivind, Haugen, Aage, Phillips, David H, Machala, Miroslav, Topinka, Jan, Mollerup, Steen

“…ObjectivesThis study aimed to assess the biological impact of occupational exposure to diesel exhaust (DE) including DE particles (DEP) from heavy-duty…”
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A comprehensive analysis of phase I and phase II metabolism gene polymorphisms and risk of non-small cell lung cancer in smokers by Zienolddiny, Shanbeh, Campa, Daniele, Lind, Helge, Ryberg, David, Skaug, Vidar, Stangeland, Lodve B., Canzian, Federico, Haugen, Aage

“…Lung cancer is a leading cause of cancer mortality worldwide with smoking and occupational exposure to carcinogenic compounds as the major risk factors…”
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Genome-Wide Analysis of Survival in Early-Stage Non–Small-Cell Lung Cancer by HUANG, Yen-Tsung, HEIST, Rebecca S, ASOMANING, Kofi, CHRISTIANI, David C, CHIRIEAC, Lucian R, XIHONG LIN, SKAUG, Vidar, ZIENOLDDINY, Shanbeh, HAUGEN, Aage, WU, Michael C, ZHAOXI WANG, LI SU

“…Lung cancer, of which 85% is non-small-cell (NSCLC), is the leading cause of cancer-related death in the United States. We used genome-wide analysis of tumor…”
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Combination of Protein Coding and Noncoding Gene Expression as a Robust Prognostic Classifier in Stage I Lung Adenocarcinoma by AKAGI, Ichiro, OKAYAMA, Hirokazu, MIYASHITA, Masao, UCHIDA, Eiji, TAKIZAWA, Toshihiro, TAKENOSHITA, Seiichi, SKAUG, Vidar, MOLLERUP, Steen, HAUGEN, Aage, YOKOTA, Jun, HARRIS, Curtis C, SCHETTER, Aaron J, ROBLES, Ana I, KOHNO, Takashi, BOWMAN, Elise D, KAZANDJIAN, Dickran, WELSH, Judith A, OUE, Naohide, SAITO, Motonobu

“…Prognostic tests for patients with early-stage lung cancer may provide needed guidance on postoperative surveillance and therapeutic decisions. We used a novel…”
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Sex differences in risk of lung cancer: Expression of genes in the PAH bioactivation pathway in relation to smoking and bulky DNA adducts by Mollerup, Steen, Berge, Gisle, Bæra, Rita, Skaug, Vidar, Hewer, Alan, Phillips, David H., Stangeland, Lodve, Haugen, Aage

“…It is controversial whether women have a higher lung cancer susceptibility compared to men. We previously reported higher levels of smoking‐related bulky DNA…”
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Association of the FAM46A gene VNTRs and BAG6 rs3117582 SNP with non small cell lung cancer (NSCLC) in Croatian and Norwegian populations by Etokebe, Godfrey Essien, Zienolddiny, Shanbeh, Kupanovac, Zeljko, Enersen, Morten, Balen, Sanja, Flego, Veljko, Bulat-Kardum, Ljiljana, Radojčić-Badovinac, Anđelka, Skaug, Vidar, Bakke, Per, Haugen, Aage, Dembic, Zlatko

“…We analyzed for associations between a variable number of tandem repeat (VNTR) polymorphism in the Family with sequence similarity 46, member A (FAM46A) gene…”
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Functional analysis of a lung cancer risk haplotype in the IL1B gene regulatory region by Landvik, Nina E, Hart, Kent, Haugen, Aage, Zienolddiny, Shanbeh

“…Interleukin-1β (IL-1β), encoded by the IL1B gene, is a cytokine important in regulation of the inflammatory response. Elevated levels of IL1B expression have…”
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A Two-Gene Prognostic Classifier for Early-Stage Lung Squamous Cell Carcinoma in Multiple Large-Scale and Geographically Diverse Cohorts by Noro, Rintaro, Ishigame, Teruhide, Walsh, Naomi, Shiraishi, Kouya, Robles, Ana I, Ryan, Bríd M, Schetter, Aaron J, Bowman, Elise D, Welsh, Judith A, Seike, Masahiro, Gemma, Akihiko, Skaug, Vidar, Mollerup, Steen, Haugen, Aage, Yokota, Jun, Kohno, Takashi, Harris, Curtis C

“…There are no validated molecular methods that prospectively identify patients with surgically resected lung squamous cell carcinoma (SCC) at high risk for…”
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Cigarette smoking increases copy number alterations in nonsmall-cell lung cancer by Huang, Yen-Tsung, Lin, Xihong, Liu, Yan, Chirieac, Lucian R., McGovern, Ray, Wain, John, Heist, Rebecca, Skaug, Vidar, Zienolddiny, Shanbeh, Haugen, Aage, Su, Li, Fox, Edward A., Wong, Kwok-Kin, Christiani, David C.

“…Cigarette smoking has been a well-established risk factor of lung cancer for decades. How smoking contributes to tumorigenesis in the lung remains not fully…”
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Sex differences in susceptibility to PAHs is an intrinsic property of human lung adenocarcinoma cells by Uppstad, Heidi, Osnes, Gro Helene, Cole, Kathleen J, Phillips, David H, Haugen, Aage, Mollerup, Steen

“…Abstract Recent epidemiological studies have disputed whether females are at increased risk of lung cancer compared to males. However, several molecular…”
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Women who smoke: are women more susceptible to tobacco-induced lung cancer? by Haugen, Aage

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Impact on disease development, genomic location and biological function of copy number alterations in non-small cell lung cancer by Huang, Yen-Tsung, Lin, Xihong, Chirieac, Lucian R, McGovern, Ray, Wain, John C, Heist, Rebecca S, Skaug, Vidar, Zienolddiny, Shanbeh, Haugen, Aage, Su, Li, Christiani, David C

“…Lung cancer, of which more than 80% is non-small cell, is the leading cause of cancer-related death in the United States. Copy number alterations (CNAs) in…”
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Quantitative analysis of benzo[ a]pyrene biotransformation and adduct formation in Ahr knockout mice by Sagredo, Carlos, Øvrebø, Steinar, Haugen, Aage, Fujii-Kuriyama, Yoshiaki, Bæra, Rita, Botnen, Ingrid V., Mollerup, Steen

“…Benzo[ a]pyrene (BP) is an ubiquitous environmental pollutant with potent mutagenic and carcinogenic properties. The Ah receptor (Ahr) is involved in the…”
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Induction of microsatellite mutations by oxidative agents in human lung cancer cell lines by Zienolddiny, Shanbeh, Ryberg, David, Haugen, Aage

“…Genomic instability has been associated with cancer development. Oxidative DNA damage seems to contribute to genetic instability observed in cancer. We have…”
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Frequency of TP53 Mutations in Relation to Arg72Pro Genotypes in Non–Small Cell Lung Cancer by LIND, Helge, OLAF EKSTROM, Per, RYBERG, David, SKAUG, Vidar, ANDREASSEN, Tove, STANGELAND, Lodve, HAUGEN, Aage, ZIENOLDDINY, Shanbeh

“…Mutations in the TP53 gene are important events during human lung carcinogenesis. The TP53 gene harbors several polymorphisms, and functional studies have…”
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