Search Results - "HATTORI, Kimihiko"
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The SOCS Box of SOCS-1 Accelerates Ubiquitin-dependent Proteolysis of TEL-JAK2
Published in The Journal of biological chemistry (20-04-2001)“…Fusion of the TEL gene on 12p13 to the JAK2 tyrosine kinase gene on 9p24 has been found in human leukemia. TEL -mediated oligomerization of JAK2 results in…”
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Nitric oxide production during cerebral ischemia and reperfusion in eNOS- and nNOS-knockout mice
Published in Current neurovascular research (01-02-2010)“…The purpose of this study was to clarify the kinetics of nitric oxide (NO) induced by either endothelial NO synthase (eNOS) or neuronal NO synthase (nNOS)…”
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Histopathological and behavioral characterization of a novel model of cardiac arrest and cardiopulmonary resuscitation in mice
Published in Journal of neuroscience methods (15-06-2004)“…Cardiac arrest is associated with high mortality and poor neurological outcome. We characterized functional and histological outcome in a novel mouse model of…”
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Cognitive deficits after focal cerebral ischemia in mice
Published in Stroke (1970) (01-08-2000)“…The interpretation of cognitive data in many experimental stroke studies is problematic because middle cerebral artery occlusion (MCAO) is associated with…”
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Social Stress Exacerbates Stroke Outcome by Suppressing Bcl-2 Expression
Published in Proceedings of the National Academy of Sciences - PNAS (25-09-2001)“…The relationship between stressful life events and the onset of disease is well documented. However, the role of psychological stress as a risk factor for…”
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Ubiquitin-Dependent Degradation of Iκ Bα is Mediated by a Ubiquitin Ligase Skp1/Cul 1/F-Box Protein FWD1
Published in Proceedings of the National Academy of Sciences - PNAS (30-03-1999)“…Activation of the transcription factor nuclear factor kappa B (NF-κ B) is controlled by proteolysis of its inhibitory subunit (Iκ B) via the…”
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Social stress exacerbates focal cerebral ischemia in mice
Published in Stroke (1970) (01-06-2002)“…The purpose of the present study was to determine whether exposure to stress or elevated corticosterone concentrations in the days preceding cerebral ischemia…”
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Significance of Clinical–Diffusion Mismatch in Hyperacute Cerebral Infarction
Published in Journal of stroke and cerebrovascular diseases (2011)“…In recent years, patient selection for intravenous tissue plasminogen activator (t-PA) therapy based on clinical–diffusion mismatch (CDM) has been closely…”
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A case of hypoxic encephalopathy with delayed exacerbation
Published in International journal of general medicine (01-10-2008)“…Most patients contract hypoxic encephalopathy after suffering a cardiac arrest. They usually endure severe neurological sequelae and the temporal profile of…”
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Substituent Distribution in Cellulose Acetates: Its Control and the Effect on Structure Formation in Solution
Published in Journal of colloid and interface science (15-08-2000)“…Architecture-regulated cellulose derivatives were prepared by regioselective substitution of C-2, -3, and -6 position hydroxyls in cellulose by O-acetyls or…”
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Regioselectively Substituted 6-O- and 2,3-Di-O-acetyl-6-O-triphenylmethylcellulose: Its Chain Dynamics and Hydrophobic Association in Polar Solvents
Published in Biomacromolecules (2001)“…Two kinds of regioselectively substituted cellulose derivatives, i.e., 6-O-triphenylmethylcellulose (6TC) and 2,3-di-O-acetyl-6-O-triphenylmethylcellulose…”
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A TSH/Dibutyryl cAMP Activated Cl−/I− Channel in FRTL-5 Cells
Published in Biochemical and biophysical research communications (16-06-1999)“…An iodide (I) and chloride (Cl) channel has been identified in the continuously cultured FRTL-5 thyroid cell line using a cell attached patch clamp technique…”
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Spatial and Intracellular Distribution of the Endogenous Calcineurin-Inhibitory Proteins, ZAKI-4, in Mouse Brain
Published in ACTA HISTOCHEMICA ET CYTOCHEMICA (01-01-2004)“…ZAKI-4 is a thyroid hormone-responsive gene which encodes two isoforms, ZAKI-4 α and β, both of which belong to a family of proteins that inhibit calcineurin…”
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Laser-induced thrombus formation in mouse brain microvasculature: effect of clopidogrel
Published in Journal of thrombosis and thrombolysis (01-08-2012)“…Antiplatelet drugs have been evaluated by measuring platelet aggregation ex vivo, but in vivo studies were scanty. The purpose of this study was to observe the…”
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Color-coded Doppler Imaging of Subclavian Steal Syndrome
Published in Internal Medicine (1998)“…We examined the usefulness of color-coded Doppler echography for evaluating hemodynamics in patients with subclavian steal syndrome. Eighteen patients with…”
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An F-box protein, FWD1, mediates ubiquitin-dependent proteolysis of β-catenin
Published in The EMBO journal (04-05-1999)“…β‐catenin plays an essential role in the Wingless/Wnt signaling cascade and is a component of the cadherin cell adhesion complex. Deregulation of β‐catenin…”
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Cardiac Angiosarcoma
Published in Internal Medicine (1996)“…Angiosarcoma is one of the most common cardiac tumors, but early detection of this tumor is often difficult, as exemplified by our patient, a 55-year-old woman…”
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Common Pathway for the Ubiquitination of IκBα, IκBβ, and IκBε Mediated by the F-Box Protein FWD1
Published in The Journal of biological chemistry (01-10-1999)“…FWD1 (the mouse homolog of DrosophilaSlimb and Xenopus βTrCP, a member of the F-box- and WD40 repeat-containing family of proteins, and a component of the SCF…”
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Molecular Dissection of the Interactions among IκBα, FWD1, and Skp1 Required for Ubiquitin-mediated Proteolysis of IκBα
Published in The Journal of biological chemistry (15-10-1999)“…The SCF complex containing Skp1, Cul1, and the F-box protein FWD1 (the mouse homologue of Drosophila Slimb and Xenopus β-TrCP) functions as the ubiquitin…”
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