Search Results - "HATORI, C"

The identification of an orally active, nonpeptide bradykinin B 2 receptor antagonist, FR173657 by Asano, Masayuki, Inamura, Noriaki, Hatori, Chie, Sawai, Hiroe, Fujiwara, Tatsujiro, Katayama, Akira, Kayakiri, Hiroshi, Satoh, Shigeki, Abe, Yoshito, Inoue, Takayuki, Sawada, Yuki, Nakahara, Kunio, Oku, Teruo, Okuhara, Masakuni

“…An orally active, nonpeptide bradykinin (BK) B 2 receptor antagonist, FR173657 (E)‐3‐(6‐acetamido‐3‐pyridyl)‐N‐[N‐[2‐4‐dichloro‐3‐[(2‐methyl‐8‐quinolinyl)…”
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Characterization of FR173657, a novel nonpeptide B2 antagonist: in vitro and in vivo studies by Inamura, N, Asano, M, Kayakiri, H, Hatori, C, Oku, T, Nakahara, K

“…Bradykinin (BK) is involved in different pathophysiological conditions, including allergic and (or) inflammatory reactions. Thus, BK antagonists are considered…”
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Discovery of the First Non-Peptide Full Agonists for the Human Bradykinin B 2 Receptor Incorporating 4-(2-Picolyloxy)quinoline and 1-(2-Picolyl)benzimidazole Frameworks by Sawada, Yuki, Kayakiri, Hiroshi, Abe, Yoshito, Mizutani, Tsuyoshi, Inamura, Noriaki, Asano, Masayuki, Hatori, Chie, Aramori, Ichiro, Oku, Teruo, Tanaka, Hirokazu

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Effects of a nonpeptide bradykinin B 2 receptor antagonist, FR167344, on different in vivo animal models of inflammation by Asano, Masayuki, Hatori, Chie, Inamura, Noriaki, Sawai, Hiroe, Hirosumi, Jiro, Fujiwara, Tatsujiro, Nakahara, Kunio

“…The effects of a novel, potent and orally active nonpeptide bradykinin B 2 receptor antagonist, FR167344 (N ‐[N ‐[3 ‐[(3 ‐ bromo‐ 2…”
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Antinociceptive effects of AS1892802, a novel Rho kinase inhibitor, in rat models of inflammatory and noninflammatory arthritis by Yoshimi, Eiji, Kumakura, Fumiyo, Hatori, Chie, Hamachi, Emi, Iwashita, Akinori, Ishii, Noe, Terasawa, Takeshi, Shimizu, Yasuaki, Takeshita, Nobuaki

“…Rho kinase (ROCK) is involved in various physiological functions, including cell motility, vasoconstriction, and neurite extension. Although a functional role…”
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Pharmacological characterization of a nonpeptide bradykinin B 2 receptor antagonist, FR165649, and agonist, FR190997 by Asano, Masayuki, Hatori, Chie, Sawai, Hiroe, Johki, Shigeru, Inamura, Noriaki, Kayakiri, Hiroshi, Satoh, Shigeki, Abe, Yoshito, Inoue, Takayuki, Sawada, Yuki, Mizutani, Tsuyoshi, Oku, Teruo, Nakahara, Kunio

“…The nonpeptide bradykinin (BK) B 2 receptor antagonist, FR165649 (8‐[2,6‐dichloro‐3‐[N‐[(E)‐4‐(N‐ methylcarbamoyl)cinnamidoacetyl] ‐N‐methylamino] benzyloxy]…”
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A New Series of Highly Potent Non-Peptide Bradykinin B 2 Receptor Antagonists Incorporating the 4-Heteroarylquinoline Framework. Improvement of Aqueous Solubility and New Insights into Species Difference by Sawada, Yuki, Kayakiri, Hiroshi, Abe, Yoshito, Imai, Keisuke, Mizutani, Tsuyoshi, Inamura, Noriaki, Asano, Masayuki, Aramori, Ichiro, Hatori, Chie, Katayama, Akira, Oku, Teruo, Tanaka, Hirokazu

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A Novel Class of Orally Active Non-Peptide Bradykinin B 2 Receptor Antagonists. 1. Construction of the Basic Framework by Abe, Yoshito, Kayakiri, Hiroshi, Satoh, Shigeki, Inoue, Takayuki, Sawada, Yuki, Imai, Keisuke, Inamura, Noriaki, Asano, Masayuki, Hatori, Chie, Katayama, Akira, Oku, Teruo, Tanaka, Hirokazu

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A Novel Class of Orally Active Non-Peptide Bradykinin B2 Receptor Antagonists. 1. Construction of the Basic Framework by Abe, Yoshito, Kayakiri, Hiroshi, Satoh, Shigeki, Inoue, Takayuki, Sawada, Yuki, Imai, Keisuke, Inamura, Noriaki, Asano, Masayuki, Hatori, Chie, Katayama, Akira, Oku, Teruo, Tanaka, Hirokazu

“…A novel class of potent, selective, and orally active non-peptide bradykinin (BK) B2 receptor antagonists were designed and synthesized starting from…”
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A Novel Class of Orally Active Non-Peptide Bradykinin B 2 Receptor Antagonists. 3. Discovering Bioisosteres of the Imidazo[1,2- a ]pyridine Moiety by Abe, Yoshito, Kayakiri, Hiroshi, Satoh, Shigeki, Inoue, Takayuki, Sawada, Yuki, Inamura, Noriaki, Asano, Masayuki, Aramori, Ichiro, Hatori, Chie, Sawai, Hiroe, Oku, Teruo, Tanaka, Hirokazu

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A New Class of Nonpeptide Bradykinin B 2 Receptor Ligand, Incorporating a 4-Aminoquinoline Framework. Identification of a Key Pharmacophore To Determine Species Difference and Agonist/Antagonist Profile by Sawada, Yuki, Kayakiri, Hiroshi, Abe, Yoshito, Mizutani, Tsuyoshi, Inamura, Noriaki, Asano, Masayuki, Aramori, Ichiro, Hatori, Chie, Oku, Teruo, Tanaka, Hirokazu

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Novel potent antagonists of human neuropeptide Y-Y5 receptor. Part 4: Tetrahydrodiazabenzazulene derivatives by SATOH, Yoshinari, HATORI, Chie, ITO, Harunobu

“…Novel tetrahydrodiazabenzazulene derivatives, designed from the lead compound 1 discovered by screening of our in-house chemical library, were prepared and…”
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Integrating MPEG-7 descriptors and pattern recognition: an environment for multimedia indexing and searching by Matushima, R., Hiramatsu, D.M., Silveira, R.M., Ruggiero, W.V., da Costa, C.E.M., Monteiro, M.M., Hatori, C.

“…This paper describes a music searching system based on an automatic indexing process created over a pattern recognition tool and MPEG-7 standard. We present a…”
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A Novel Class of Orally Active Non-Peptide Bradykinin B2 Receptor Antagonists. 3. Discovering Bioisosteres of the Imidazo[1,2-a]pyridine Moiety by Abe, Yoshito, Kayakiri, Hiroshi, Satoh, Shigeki, Inoue, Takayuki, Sawada, Yuki, Inamura, Noriaki, Asano, Masayuki, Aramori, Ichiro, Hatori, Chie, Sawai, Hiroe, Oku, Teruo, Tanaka, Hirokazu

“…Recently we reported on overcoming the species difference of our first orally active non-peptide bradykinin (BK) B2 receptor antagonists, incorporating an…”
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The identification of an orally active, nonpeptide bradykinin B2 receptor antagonist, FR173657 by Asano, Masayuki, Inamura, Noriaki, Hatori, Chie, Sawai, Hiroe, Fujiwara, Tatsujiro, Katayama, Akira, Kayakiri, Hiroshi, Satoh, Shigeki, Abe, Yoshito, Inoue, Takayuki, Sawada, Yuki, Nakahara, Kunio, Oku, Teruo, Okuhara, Masakuni

“…1 An orally active, nonpeptide bradykinin (BK) B2 receptor antagonist, FR173657 (E)‐3‐(6‐acetamido‐3‐pyridyl)‐N‐[N‐[2‐4‐dichloro‐3‐[(2‐methyl‐8‐quinolinyl)…”
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A Novel Class of Orally Active Non-Peptide Bradykinin B 2 Receptor Antagonists. 4. Discovery of Novel Frameworks Mimicking the Active Conformation by Abe, Yoshito, Kayakiri, Hiroshi, Satoh, Shigeki, Inoue, Takayuki, Sawada, Yuki, Inamura, Noriaki, Asano, Masayuki, Aramori, Ichiro, Hatori, Chie, Sawai, Hiroe, Oku, Teruo, Tanaka, Hirokazu

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A Novel Class of Orally Active Non-Peptide Bradykinin B2 Receptor Antagonists. 4. Discovery of Novel Frameworks Mimicking the Active Conformation by Abe, Yoshito, Kayakiri, Hiroshi, Satoh, Shigeki, Inoue, Takayuki, Sawada, Yuki, Inamura, Noriaki, Asano, Masayuki, Aramori, Ichiro, Hatori, Chie, Sawai, Hiroe, Oku, Teruo, Tanaka, Hirokazu

“…In recent articles we reported the identification of a series of…”
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A Novel Class of Orally Active Non-Peptide Bradykinin B2 Receptor Antagonists. 2. Overcoming the Species Difference between Guinea Pig and Man by Abe, Yoshito, Kayakiri, Hiroshi, Satoh, Shigeki, Inoue, Takayuki, Sawada, Yuki, Inamura, Noriaki, Asano, Masayuki, Hatori, Chie, Sawai, Hiroe, Oku, Teruo, Tanaka, Hirokazu

“…Recently we reported the identification of a series of 8-[[3-(N-acylglycyl-N-methylamino)-2,6-dichlorobenzyl]oxy]-3-halo-2-methylimidazo[1,2-a]pyridines as the…”
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Nonpeptide mimic of bradykinin with long-acting properties at the bradykinin B2 receptor by Aramori, I, Zenkoh, J, Morikawa, N, Asano, M, Hatori, C, Sawai, H, Kayakiri, H, Satoh, S, Inoue, T, Abe, Y, Sawada, Y, Mizutani, T, Inamura, N, Nakahara, K, Kojo, H, Oku, T, Notsu, Y

“…Kinins, members of a family of peptides released from kininogens by the action of kallikreins, exhibit a variety of biological activities including…”
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Effects of a nonpeptide bradykinin B2 receptor antagonist, FR167344, on different in vivo animal models of inflammation by Asano, Masayuki, Hatori, Chie, Inamura, Noriaki, Sawai, Hiroe, Hirosumi, Jiro, Fujiwara, Tatsujiro, Nakahara, Kunio

“…1 The effects of a novel, potent and orally active nonpeptide bradykinin B2 receptor antagonist, FR167344 (N ‐[N ‐[3 ‐[(3 ‐ bromo‐ 2…”
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