Search Results - "HATO, Fumihiko"

Toll-like receptor agonists stimulate human neutrophil migration via activation of mitogen-activated protein kinases by Aomatsu, Kazuki, Kato, Takayuki, Fujita, Hisakazu, Hato, Fumihiko, Oshitani, Nobuhide, Kamata, Noriko, Tamura, Tomohiko, Arakawa, Tetsuo, Kitagawa, Seiichi

“…Human neutrophil migratory responses to Toll-like receptor (TLR) agonists were studied using videomicroscopy. When challenged with lipopolysaccharide (LPS,…”
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Neutrophil Elastase as a Predicting Factor for Development of Acute Lung Injury by Kodama, Tadatomo, Yukioka, Hidekazu, Kato, Takayuki, Kato, Noboru, Hato, Fumihiko, Kitagawa, Seiichi

“…Objective To determine whether the development of acute lung injury (ALI) and acute respiratory distress syndrome (ARDS) associated with systemic inflammatory…”
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Actin reorganization and morphological changes in human neutrophils stimulated by TNF, GM-CSF, and G-CSF: the role of MAP kinases by Kutsuna, Haruo, Suzuki, Kenichi, Kamata, Noriko, Kato, Takayuki, Hato, Fumihiko, Mizuno, Kensaku, Kobayashi, Hiromi, Ishii, Masamitsu, Kitagawa, Seiichi

“…Stimulation of human neutrophils with tumor necrosis factor-alpha (TNF), granulocyte-macrophage colony-stimulating factor (GM-CSF), or granulocyte CSF (G-CSF)…”
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Type I and type II interferons delay human neutrophil apoptosis via activation of STAT3 and up-regulation of cellular inhibitor of apoptosis 2 by Sakamoto, Erina, Hato, Fumihiko, Kato, Takayuki, Sakamoto, Chikahiko, Akahori, Mika, Hino, Masayuki, Kitagawa, Seiichi

“…We have recently demonstrated that granulocyte‐colony stimulating factor (G‐CSF) delays human neutrophil apoptosis via up‐regulation of cellular inhibitor of…”
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Peroxisome Proliferator‐activated Receptor Gamma Activation Induces Cell Cycle Arrest via the p53‐independent Pathway in Human Anaplastic Thyroid Cancer Cells by Chung, Sung Hwa, Onoda, Naoyoshi, Ishikawa, Tetsuro, Ogisawa, Kana, Takenaka, Chiemi, Yano, Yoshihisa, Hato, Fumihiko, Hirakawa, Kosei

“…Anaplastic thyroid carcinoma is one of the most aggressive human malignancies. Outcomes of intensive multimodal therapy have been far from satisfactory…”
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Enhanced neutrophil motility by granulocyte colony‐stimulating factor: the role of extracellular signal‐regulated kinase and phosphatidylinositol 3‐kinase by Nakamae‐Akahori, Mika, Kato, Takayuki, Masuda, Sayuri, Sakamoto, Erina, Kutsuna, Haruo, Hato, Fumihiko, Nishizawa, Yoshiki, Hino, Masayuki, Kitagawa, Seiichi

“…Summary The effect of granulocyte colony‐stimulating factor (G‐CSF) on human neutrophil motility was studied using videomicroscopy. Stimulation of neutrophils…”
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Antiapoptotic effect of granulocyte colony-stimulating factor, granulocyte-macrophage colony-stimulating factor, and cyclic amp on human neutrophils: Protein synthesis-dependent and protein synthesis-independent mechanisms and the role of the Janus kinase-STAT pathway by SAKAMOTO, Chikahiko, SUZUKI, Kenichi, HATO, Fumihiko, AKAHORI, Mika, HASEGAWA, Taro, HINO, Masayuki, KITAGAWA, Seiichi

“…Spontaneous neutrophil apoptosis during culture was delayed by granulocyte colony-stimulating factor (G-CSF), granulocyte-macrophage CSF (GM-CSF), or…”
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Activation of Human Neutrophil by Cytokine-Activated Endothelial Cells by Takahashi, Tatsuji, Hato, Fumihiko, Yamane, Takahisa, Fukumasu, Hiroshi, Suzuki, Kenichi, Ogita, Sachio, Nishizawa, Yoshiki, Kitagawa, Seiichi

“…ABSTRACT—Cytokine activation of vascular endothelial cells renders the hyperadhesiveness for neutrophils. During the processes of inflammation and…”
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Neutrophil-activating activity and platelet-activating factor synthesis in cytokine-stimulated endothelial cells: Reduced activity in growth-arrested cells by Takahashi, Tatsuji, Nishizawa, Yoshiki, Hato, Fumihiko, Shintaku, Haruo, Maeda, Nobuji, Fujiwara, Nagatoshi, Inaba, Masaaki, Kobayashi, Kazuo, Kitagawa, Seiichi

“…The reactivity of endothelial cells (ECs) to proinflammatory cytokines is critically important for the pathogenesis of vascular diseases. Here, we studied…”
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Activation of human neutrophils by granulocyte colony-stimulating factor, granulocyte-macrophage colony-stimulating factor, and tumor necrosis factor α: Role of phosphatidylinositol 3-kinase by KAMATA, Noriko, KUTSUNA, Haruo, HATO, Fumihiko, KATO, Takayuki, OSHITANI, Nobuhide, ARAKAWA, Tetsuo, KITAGAWA, Seiichi

“…Stimulation of human neutrophils with granulocyte colony-stimulating factor (G-CSF), granulocyte-macrophage CSF (GM-CSF), or tumor necrosis factor alpha (TNF)…”
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Cleavage of Mitogen-Activated Protein Kinases in Human Neutrophils Undergoing Apoptosis: Role in Decreased Responsiveness to Inflammatory Cytokines by Suzuki, Kenichi, Hasegawa, Taro, Sakamoto, Chikahiko, Zhou, Yue-Min, Hato, Fumihiko, Hino, Masayuki, Tatsumi, Noriyuki, Kitagawa, Seiichi

“…Extracellular signal-regulated kinase (ERK) and p38 mitogen-activated protein kinase (MAPK) are major signaling molecules activated in human neutrophils…”
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Activation of Human Neutrophils by Granulocyte Colony-Stimulating Factor, Granulocyte-Macrophage Colony-Stimulating Factor, and Tumor Necrosis Factor 3: Role of Phosphatidylinositol 3-Kinase by Kamata, Noriko, Kutsuna, Haruo, Hato, Fumihiko, Kato, Takayuki, Oshitani, Nobuhide, Arakawa, Tetsuo, Kitagawa, Seiichi

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Serine Protease Inhibitors Inhibit Superoxide Release and Adherence in Human Neutrophils Stimulated by Granulocyte-Macrophage Colony-Stimulating Factor and Tumor Necrosis Factor-α by ZHOU, Yue-Min, KUTSUNA, Haruo, SUZUKI, Kenichi, HATO, Fumihiko, KITAGAWA, Seiichi

“…Stimulation of human neutrophils with granulocyte-macrophage colony-stimulating factor (GM-CSF) or tumor necrosis factor-alpha (TNF) results in increased…”
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Distinct elevation of levels of anti-Caenorhabditis elegans antibody in sera of patients with inflammatory bowel disease by Oshitani, Nobuhide, Hato, Fumihiko, Kitagawa, Seiichi, Watanabe, Kenji, Fujiwara, Yasuhiro, Higuchi, Kazuhide, Matsumoto, Takayuki, Arakawa, Tetsuo

“…Dysregulation of immune responses to intestinal exogenous antigens contributes to the pathogenesis of inflammatory bowel disease, but the specific antigen…”
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Cytokine-Specific Activation of Distinct Mitogen-Activated Protein Kinase Subtype Cascades in Human Neutrophils Stimulated by Granulocyte Colony-Stimulating Factor, Granulocyte-Macrophage Colony-Stimulating Factor, and Tumor Necrosis Factor- by Suzuki, Kenichi, Hino, Masayuki, Hato, Fumihiko, Tatsumi, Noriyuki, Kitagawa, Seiichi

“…Abstract To clarify the differences of the signaling pathways used by granulocyte colony-stimulating factor (G-CSF), granulocyte-macrophage colony-stimulating…”
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Cytokine-Specific Activation of Distinct Mitogen-Activated Protein Kinase Subtype Cascades in Human Neutrophils Stimulated by Granulocyte Colony-Stimulating Factor, Granulocyte-Macrophage Colony-Stimulating Factor, and Tumor Necrosis Factor- by Suzuki, Kenichi, Hino, Masayuki, Hato, Fumihiko, Tatsumi, Noriyuki, Kitagawa, Seiichi

“…To clarify the differences of the signaling pathways used by granulocyte colony-stimulating factor (G-CSF), granulocyte-macrophage colony-stimulating factor…”
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Erythrophagocytosis by Liver Macrophages (Kupffer Cells) Promotes Oxidative Stress, Inflammation, and Fibrosis in a Rabbit Model of Steatohepatitis: Implications for the Pathogenesis of Human Nonalcoholic Steatohepatitis by Otogawa, Kohji, Kinoshita, Kohji, Fujii, Hideki, Sakabe, Masahide, Shiga, Ryoko, Nakatani, Kazuki, Ikeda, Kazuo, Nakajima, Yuji, Ikura, Yoshihiro, Ueda, Makiko, Arakawa, Tetsuo, Hato, Fumihiko, Kawada, Norifumi

“…Nonalcoholic steatohepatitis (NASH) is a progressive fibrotic disease, the pathogenesis of which has not been fully elucidated. Here, we report a molecular…”
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Cytokine-specific activation of distinct mitogen-activated protein kinase subtype cascades in human neutrophils stimulated by granulocyte colony-stimulating factor, granulocyte-macrophage colony-stimulating factor, and tumor necrosis factor-α by SUZUKI, K, HINO, M, HATO, F, TATSUMI, N, KITAGAWA, S

“…To clarify the differences of the signaling pathways used by granulocyte colony-stimulating factor (G-CSF), granulocyte-macrophage colony-stimulating factor…”
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Calcium Channel Blockers Suppress Cytokine-induced Activation of Human Neutrophils by Shima, Etsuko, Katsube, Masataka, Kato, Takayuki, Kitagawa, Maki, Hato, Fumihiko, Hino, Masayuki, Takahashi, Tatsuji, Fujita, Hisakazu, Kitagawa, Seiichi

“…Background Neutrophils, in concert with proinflammatory cytokines, play an important role in the progression of atherosclerosis. Calcium channel blockers are…”
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Selective Activation of p38 Mitogen-Activated Protein Kinase Cascade in Human Neutrophils Stimulated by IL-1β by Suzuki, Kenichi, Hino, Masayuki, Kutsuna, Haruo, Hato, Fumihiko, Sakamoto, Chikahiko, Takahashi, Tatsuji, Tatsumi, Noriyuki, Kitagawa, Seiichi

“…Abstract We investigated activation of mitogen-activated protein kinase (MAPK) subtype cascades in human neutrophils stimulated by IL-1β. IL-1β induced…”
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