Search Results - "HATA, TAISHI"
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Disruption of Endolysosomal RAB5/7 Efficiently Eliminates Colorectal Cancer Stem Cells
Published in Cancer research (Chicago, Ill.) (01-04-2019)“…Given that cancer stem cells (CSC) play a key role in drug resistance and relapse, targeting CSCs remains promising in cancer therapy. Here we show that…”
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2
Photodynamic Therapy Using Indocyanine Green Loaded on Super Carbonate Apatite as Minimally Invasive Cancer Treatment
Published in Molecular cancer therapeutics (01-07-2018)“…Minimally invasive treatment is getting more and more important in an aging society. The purpose of this study was to explore the possibility of ICG loaded on…”
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3
Factors predictive of high-output ileostomy: a retrospective single-center comparative study
Published in Surgery today (Tokyo, Japan) (01-06-2019)“…Purpose High-output syndrome (HOS) is a complication of ileostomy, which can affect quality of life significantly; however, its exact cause remains unknown…”
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Incidence and risk factors for venous thromboembolism, bleeding, and death in colorectal cancer (Cancer‐VTE Registry)
Published in Cancer science (01-11-2022)“…The impact of venous thromboembolism in Japanese colorectal cancer patients has not been elucidated. This prespecified subanalysis of the Cancer‐VTE Registry…”
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5
Development of novel rectal/uterine clamping device
Published in Scientific reports (03-10-2024)“…We developed a novel clamping device for laparoscopic surgery, free from conventional pinch structure, capable of uniformly occluding any ductal organ. This…”
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6
DCLK1 integrates induction of TRIB3, EMT, drug resistance and poor prognosis in colorectal cancer
Published in Carcinogenesis (New York) (14-05-2020)“…Abstract Doublecortin-like kinase 1 (DCLK1) promotes tumour proliferation in human colorectal cancer (CRC). To elucidate the mechanism and clinical relevance…”
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Safety and efficacy of laparoscopic repeat liver resection and re-operation for liver tumor
Published in Scientific reports (02-06-2021)“…Laparoscopic liver resection (LLR) has been reported as a safe, minimally invasive, and effective surgery for the management of liver tumor. However, the…”
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Fructose-bisphosphate aldolase A is a key regulator of hypoxic adaptation in colorectal cancer cells and involved in treatment resistance and poor prognosis
Published in International journal of oncology (01-02-2017)“…Hypoxia is an essential feature of cancer malignancy, but there are no methods for the routine detection of hypoxia-inducible prognostic factors and potential…”
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Phase II trial evaluating the long-term efficacy and peripheral sensory neuropathy of capecitabine plus oxaliplatin (XELOX) as adjuvant therapy in Japanese patients with operated stage III colon cancer
Published in Scientific reports (02-11-2024)“…Adjuvant oxaliplatin plus capecitabine (XELOX) therapy is recommended for patients with curatively resected colon cancer. However, prospective data on its…”
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10
The inflammation–nutrition score supports the prognostic prediction of the TNM stage for colorectal cancer patients after curative resection
Published in Surgery today (Tokyo, Japan) (01-02-2020)“…Purpose Inflammation and the nutritional and immunologic status are known to be associated with the prognosis of malignant tumors. We aimed to examine…”
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Neutropenia is an indicator of outcomes in metastatic colorectal cancer patients treated with FTD/TPI plus bevacizumab: a retrospective study
Published in Cancer chemotherapy and pharmacology (01-09-2020)“…Purpose Trifluridine/tipiracil (FTD/TPI) improves the overall survival (OS) of metastatic colorectal cancer (mCRC) patients. Additionally, FTD/TPI plus…”
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12
Preoperative Evaluation of Venous Anatomy in Laparoscopic Complete Mesocolic Excision for Right Colon Cancer
Published in Annals of surgical oncology (01-06-2014)“…Purpose This study evaluated the venous variations of the right colon using preoperative three-dimensional computed tomography (3D-CT), and to investigate its…”
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13
Postoperative XELOX therapy for patients with curatively resected high-risk stage II and stage III rectal cancer without preoperative chemoradiation: a prospective, multicenter, open-label, single-arm phase II study
Published in BMC cancer (18-09-2019)“…Preoperative 5-FU-based chemoradiation is currently a standard treatment for advanced rectal cancer, particularly in Western countries. Although it reduced the…”
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14
A miR-29b Byproduct Sequence Exhibits Potent Tumor-Suppressive Activities via Inhibition of NF-κB Signaling in KRAS -Mutant Colon Cancer Cells
Published in Molecular cancer therapeutics (01-05-2018)“…We previously demonstrated that miR-29b-3p is a hopeful miRNA-based therapy against colorectal cancer. In this study, we aimed to clarify a value of…”
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15
Goshajinkigan oxaliplatin neurotoxicity evaluation (GONE): a phase 2, multicenter, randomized, double-blind, placebo-controlled trial of goshajinkigan to prevent oxaliplatin-induced neuropathy
Published in Cancer chemotherapy and pharmacology (01-12-2013)“…Purpose Oxaliplatin-induced peripheral neurotoxicity (OPN) is frequent and potentially severe, but successful treatment of this condition is still an unmet…”
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Efficacy of positron emission tomography in diagnosis of lateral lymph node metastases in patients with rectal Cancer: a retrospective study
Published in BMC cancer (08-05-2021)“…The presence of lateral pelvic lymph node (LLN) metastasis is an essential prognostic factor in rectal cancer patients. Thus, preoperative diagnosis of LLN…”
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Metabolic Adaptation to Nutritional Stress in Human Colorectal Cancer
Published in Scientific reports (07-12-2016)“…Tumor cells respond to their microenvironment, which can include hypoxia and malnutrition, and adapt their metabolism to survive and grow. Some oncogenes are…”
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Safety and efficacy of an “enhanced recovery after surgery” protocol for patients undergoing colon cancer surgery: a multi-institutional controlled study
Published in Surgery today (Tokyo, Japan) (01-06-2017)“…Purpose The aim of this multi-institutional study was to prospectively evaluate the safety and efficacy of an enhanced recovery after surgery (ERAS) protocol…”
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Robotic-assisted proximal gastrectomy using the double-flap technique for early gastric cancer with situs inversus totalis: a case report
Published in Surgical case reports (02-08-2021)“…Background The robotic system has been applied in the treatment of gastric cancer (GC), and the procedure has been found to be safe and feasible. Situs…”
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Benefits of using a self-expandable metallic stent as a bridge to surgery for right- and left-sided obstructive colorectal cancers
Published in Surgery today (Tokyo, Japan) (01-01-2019)“…Purpose To assess the benefit of placing a self-expandable metallic stent (SEMS) as a bridge to surgery for obstructive colorectal cancer (OCRC) according to…”
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