Search Results - "HASS, U"

Multiple Endocrine Disrupting Effects in Rats Perinatally Exposed to Butylparaben by Boberg, J, Axelstad, M, Svingen, T, Mandrup, K, Christiansen, S, Vinggaard, A M, Hass, U

“…Parabens comprise a group of preservatives commonly added to cosmetics, lotions, and other consumer products. Butylparaben has estrogenic and antiandrogenic…”
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Low‐dose effects of bisphenol A on mammary gland development in rats by Mandrup, K., Boberg, J., Isling, L. K., Christiansen, S., Hass, U.

“…Summary Bisphenol A (BPA) is widely used in food contact materials, toys, and other products. Several studies have indicated that effects observed at doses…”
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Dietary Inflammatory Index and Cross-Sectional Associations with Inflammation, Muscle Mass and Function in Healthy Old Adults by Haß, U., Herpich, C., Kochlik, B., Weber, D., Grune, T., Norman, Kristina

“…Importance Inflammaging is considered a driver of age-related loss of muscle mass and function (sarcopenia). As nutrition might play a role in this process,…”
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Low‐dose effect of developmental bisphenol A exposure on sperm count and behaviour in rats by Hass, U., Christiansen, S., Boberg, J., Rasmussen, M. G., Mandrup, K., Axelstad, M.

“…Summary Bisphenol A is widely used in food contact materials and other products and is detected in human urine and blood. Bisphenol A may affect reproductive…”
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Burden of disease and costs of exposure to endocrine disrupting chemicals in the European Union: an updated analysis by Trasande, L., Zoeller, R. T., Hass, U., Kortenkamp, A., Grandjean, P., Myers, J. P., DiGangi, J., Hunt, P. M., Rudel, R., Sathyanarayana, S., Bellanger, M., Hauser, R., Legler, J., Skakkebaek, N. E., Heindel, J. J.

“…Summary A previous report documented that endocrine disrupting chemicals contribute substantially to certain forms of disease and disability. In the present…”
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EDC IMPACT: Reduced sperm counts in rats exposed to human relevant mixtures of endocrine disrupters by Axelstad, M, Hass, U, Scholze, M, Christiansen, S, Kortenkamp, A, Boberg, J

“…Human semen quality is declining in many parts of the world, but the causes are ill defined. In rodents, impaired sperm production can be seen with early life…”
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Low-dose developmental exposure to bisphenol A alters the femoral bone geometry in wistar rats by Lejonklou, M.H., Christiansen, S., Örberg, J., Shen, L., Larsson, S., Boberg, J., Hass, U., Lind, P.M.

“…Bisphenol A (BPA) is a chemical produced in large volumes for use in manufacturing of consumer products and industrial applications, and an endocrine disruptor…”
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Rebuttal to letter by Morfeld et al., “Boberg et al. (2011) – Corrigendum (2016): Further significant modifications needed” by Boberg, J., Axelstad, M., Christiansen, S., Hass, U.

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Intrauterine exposure to mild analgesics during pregnancy and the occurrence of cryptorchidism and hypospadia in the offspring: the Generation R Study by Snijder, Claudia A., Kortenkamp, Andreas, Steegers, Eric A.P., Jaddoe, Vincent W.V., Hofman, Albert, Hass, Ulla, Burdorf, Alex

“…Recently, over-the-counter mild analgesic use during pregnancy has been suggested to influence the risk of reproductive disorders in the offspring. We examined…”
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Information/testing strategies for identification of substances with endocrine disrupting properties by Christiansen, S., Holbech, H., Bjerregaard, P., Hass, U.

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Current status of developmental neurotoxicity: regulatory view by Hass, U.

“…The need for developmental neurotoxicity testing has been recognized for decades and guidelines are available, as the USEPA guideline and the OECD draft TG…”
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Mixtures of endocrine disrupting contaminants modelled on human high end exposures: an exploratory study in rats by Christiansen, S., Kortenkamp, A., Axelstad, M., Boberg, J., Scholze, M., Jacobsen, P. R., Faust, M., Lichtensteiger, W., Schlumpf, M., Burdorf, A., Hass, U.

“…Summary By diminishing the action of androgens during gestation, certain chemicals can induce irreversible demasculinization and malformations of sex organs in…”
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Dysgenesis and Histological Changes of Genitals and Perturbations of Gene Expression in Male Rats after In Utero Exposure to Antiandrogen Mixtures by Metzdorff, Stine Broeng, Dalgaard, Majken, Christiansen, Sofie, Axelstad, Marta, Hass, Ulla, Kiersgaard, Maria Kristina, Scholze, Martin, Kortenkamp, Andreas, Vinggaard, Anne Marie

“…We investigated the ability of a mixture of three androgen receptor antagonists to induce disruption of male sexual differentiation after perinatal exposure…”
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Combined exposure to anti-androgens causes markedly increased frequencies of hypospadias in the rat by Christiansen, S., Scholze, M., Axelstad, M., Boberg, J., Kortenkamp, A., Hass, U.

“…Summary The incidence of hypospadias is increasing in young boys, but it remains unclear whether human exposure to endocrine disrupting chemicals plays a role…”
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Perinatal ethinyl oestradiol alters mammary gland development in male and female Wistar rats by Mandrup, K. R., Hass, U., Christiansen, S., Boberg, J.

“…Summary Increased attention is being paid to human mammary gland development because of concerns for environmental influences on puberty onset and breast…”
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Endocrine-disrupting properties in vivo of widely used azole fungicides by Taxvig, C, Vinggaard, A.M, Hass, U, Axelstad, M, Metzdorff, S, Nellemann, C

“…The endocrine-disrupting potential of four commonly used azole fungicides, propiconazole, tebuconazole, epoxiconazole and ketoconazole, were tested in two…”
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Combined exposure to endocrine disrupting pesticides impairs parturition, causes pup mortality and affects sexual differentiation in rats by Jacobsen, P.R, Christiansen, S, Boberg, J, Nellemann, C, Hass, U

“…Risk assessment is currently based on the no observed adverse effect levels (NOAELs) for single compounds. Humans are exposed to a mixture of chemicals and…”
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Comparison between women and men with recent onset rheumatoid arthritis of disease activity and functional ability over two years (the TIRA project) by Hallert, E, Thyberg, I, Hass, U, Skargren, E, Skogh, T

“…Objective: To describe the course of recent onset rheumatoid arthritis (RA) and to compare consequences of the disease in men and women. Methods: 284 patients…”
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Developmental toxicity of toluene in male rats: effects on semen quality, testis morphology, and apoptotic neurodegeneration by DALGAARD, M, HOSSAINI, A, HOUGAARD, K. S, HASS, U, LADEFOGED, O

“…In one study, pregnant Wistar rats were exposed to 1200 ppm toluene by inhalation 6 h a day from gestational day (GD) 7 to postnatal day (PND) 18. Sperm…”
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LP-26 Revealing hidden challenges: an in-depth evaluation of Anogenital Distance (AGD) and Areola/Nipple Retention (NR) assessments in EOGRT Studies, with implications for regulatory toxicology by Axelstad, M., Hass, U., Bichlmaier, I., Simanainen, U., Beausoleil, C., Deweirdt, J., Bergkvist, C., Christiansen, S.

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