Search Results - "HASLER, Melanie"

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  1. 1

    Blood Purification Using Functionalized Core/Shell Nanomagnets by Herrmann, Inge K., Urner, Martin, Koehler, Fabian M., Hasler, Melanie, Roth-Z'Graggen, Birgit, Grass, Robert N., Ziegler, Urs, Beck-Schimmer, Beatrice, Stark, Wendelin J.

    “…Injection of functional nanomagnets in human blood enables selective removal of disease‐causing metals, overdosed drugs, and proteins at the (sub‐)nanomolar…”
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    Journal Article
  2. 2

    Volatile Anesthetics Improve Survival after Cecal Ligation and Puncture by HERRMANN, Inge K, CASTELLON, Maricela, SCHWARTZ, David E, HASLER, Melanie, URNER, Martin, GUOCHANG HU, MINSHALL, Richard D, BECK-SCHIMMER, Beatrice

    Published in Anesthesiology (Philadelphia) (01-10-2013)
    “…Sepsis remains a leading cause of death in intensive care units. There is growing evidence that volatile anesthetics have beneficial immunomodulatory effects…”
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    Journal Article
  3. 3

    Effects of blood products on inflammatory response in endothelial cells in vitro by Urner, Martin, Herrmann, Inge K, Buddeberg, Felix, Schuppli, Caroline, Roth Z'graggen, Birgit, Hasler, Melanie, Schanz, Urs, Mehr, Manuela, Spahn, Donat R, Beck Schimmer, Beatrice

    Published in PloS one (16-03-2012)
    “…Transfusing blood products may induce inflammatory reactions within the vascular compartment potentially leading to a systemic inflammatory response…”
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  4. 4

    Endotoxin Removal by Magnetic Separation-Based Blood Purification by Herrmann, Inge K., Urner, Martin, Graf, Samuel, Schumacher, Christoph M., Roth-Z'graggen, Birgit, Hasler, Melanie, Stark, Wendelin J., Beck-Schimmer, Beatrice

    Published in Advanced healthcare materials (01-06-2013)
    “…This work describes a magnetic separation‐based approach using polymyxin B‐functionalized metal alloy nanomagnets for the rapid elimination of endotoxins from…”
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  5. 5

    Modulation of early inflammatory response by different balanced and non-balanced colloids and crystalloids in a rodent model of endotoxemia by Voigtsberger, Stefanie, Urner, Martin, Hasler, Melanie, Roth Z'Graggen, Birgit, Booy, Christa, Spahn, Donat R, Beck-Schimmer, Beatrice

    Published in PloS one (01-04-2014)
    “…The use of hydroxyethyl starch (HES) in sepsis has been shown to increase mortality and acute kidney injury. However, the knowledge of the exact mechanism by…”
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    Journal Article
  6. 6

    Intravenous application of a primary sevoflurane metabolite improves outcome in murine septic peritonitis: first results by Herrmann, Inge K, Castellon, Maricela, Schwartz, David E, Hasler, Melanie, Urner, Martin, Hu, Guochang, Minshall, Richard D, Beck-Schimmer, Beatrice

    Published in PloS one (19-08-2013)
    “…Volatile anesthetics are known to have immunomodulatory effects in conditions of organ injury. A recent study in an experimental sepsis model has shown…”
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  7. 7
  8. 8

    Sevoflurane attenuates systemic inflammation compared with propofol, but does not modulate neuro-inflammation: A laboratory rat study by Beck-Schimmer, Beatrice, Baumann, Lukas, Restin, Tanja, Eugster, Philipp, Hasler, Melanie, Booy, Christa, Schläpfer, Martin

    Published in European journal of anaesthesiology (01-11-2017)
    “…BACKGROUNDSeptic encephalopathy is believed to be a result of neuro-inflammation possibly triggered by endotoxins, such as lipopolysaccharides (LPS)…”
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  9. 9

    Nanomagnet-based removal of lead and digoxin from living rats by Herrmann, Inge K, Schlegel, Andrea, Graf, Rolf, Schumacher, Christoph M, Senn, Nico, Hasler, Melanie, Gschwind, Sabrina, Hirt, Ann-Marie, Günther, Detlef, Clavien, Pierre-Alain, Stark, Wendelin J, Beck-Schimmer, Beatrice

    Published in Nanoscale (21-09-2013)
    “…In a number of clinical conditions such as intoxication, bacteraemia or autoimmune diseases the removal of the disease-causing factor from blood would be the…”
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  10. 10

    Clinical concentrations of morphine are cytotoxic on proliferating human fibroblasts in vitro by Aguirre, José, Borgeat, Alain, Hasler, Melanie, Bühler, Philipp, Bonvini, John M

    Published in European journal of anaesthesiology (01-11-2016)
    “…BACKGROUNDMorphine and other opioids are routinely used systemically and as wound infusions in the postoperative period. Their effect on wound and fracture…”
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  11. 11

    Iron core/shell nanoparticles as magnetic drug carriers: possible interactions with the vascular compartment by Herrmann, Inge K, Urner, Martin, Hasler, Melanie, Roth-Z'Graggen, Birgit, Aemisegger, Caroline, Baulig, Werner, Athanassiou, Evagelos K, Regenass, Stephan, Stark, Wendelin J, Beck-Schimmer, Beatrice

    Published in Nanomedicine (London, England) (01-09-2011)
    “…Nanomagnets with metal cores have recently been shown to be promising candidates for magnetic drug delivery due to higher magnetic moments compared with…”
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    Journal Article
  12. 12

    Modulation of Early Inflammatory Response by Different Balanced and Non-Balanced Colloids and Crystalloids in a Rodent Model of Endotoxemia: e93863 by Voigtsberger, Stefanie, Urner, Martin, Hasler, Melanie, Booy, Christa, Spahn, Donat R, Beck-Schimmer, Beatrice

    Published in PloS one (01-04-2014)
    “…The use of hydroxyethyl starch (HES) in sepsis has been shown to increase mortality and acute kidney injury. However, the knowledge of the exact mechanism by…”
    Get full text
    Journal Article
  13. 13

    Nanoparticles: Endotoxin Removal by Magnetic Separation-Based Blood Purification (Adv. Healthcare Mater. 6/2013) by Herrmann, Inge K., Urner, Martin, Graf, Samuel, Schumacher, Christoph M., Roth-Z'graggen, Birgit, Hasler, Melanie, Stark, Wendelin J., Beck-Schimmer, Beatrice

    Published in Advanced healthcare materials (01-06-2013)
    “…Magnetic separation‐based blood purification enables rapid and selective removal of endotoxin and bacteria from human whole blood. Functional assays assessing…”
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    Journal Article