Search Results - "HASLER, Melanie"
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Blood Purification Using Functionalized Core/Shell Nanomagnets
Published in Small (Weinheim an der Bergstrasse, Germany) (05-07-2010)“…Injection of functional nanomagnets in human blood enables selective removal of disease‐causing metals, overdosed drugs, and proteins at the (sub‐)nanomolar…”
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Volatile Anesthetics Improve Survival after Cecal Ligation and Puncture
Published in Anesthesiology (Philadelphia) (01-10-2013)“…Sepsis remains a leading cause of death in intensive care units. There is growing evidence that volatile anesthetics have beneficial immunomodulatory effects…”
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Effects of blood products on inflammatory response in endothelial cells in vitro
Published in PloS one (16-03-2012)“…Transfusing blood products may induce inflammatory reactions within the vascular compartment potentially leading to a systemic inflammatory response…”
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Endotoxin Removal by Magnetic Separation-Based Blood Purification
Published in Advanced healthcare materials (01-06-2013)“…This work describes a magnetic separation‐based approach using polymyxin B‐functionalized metal alloy nanomagnets for the rapid elimination of endotoxins from…”
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Modulation of early inflammatory response by different balanced and non-balanced colloids and crystalloids in a rodent model of endotoxemia
Published in PloS one (01-04-2014)“…The use of hydroxyethyl starch (HES) in sepsis has been shown to increase mortality and acute kidney injury. However, the knowledge of the exact mechanism by…”
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Intravenous application of a primary sevoflurane metabolite improves outcome in murine septic peritonitis: first results
Published in PloS one (19-08-2013)“…Volatile anesthetics are known to have immunomodulatory effects in conditions of organ injury. A recent study in an experimental sepsis model has shown…”
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Fluorinated groups mediate the immunomodulatory effects of volatile anesthetics in acute cell injury
Published in American journal of respiratory cell and molecular biology (01-09-2011)“…Volatile anesthetics are known to attenuate inflammatory response and tissue damage markers in acute organ injury. It is unclear whether these beneficial…”
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Sevoflurane attenuates systemic inflammation compared with propofol, but does not modulate neuro-inflammation: A laboratory rat study
Published in European journal of anaesthesiology (01-11-2017)“…BACKGROUNDSeptic encephalopathy is believed to be a result of neuro-inflammation possibly triggered by endotoxins, such as lipopolysaccharides (LPS)…”
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Nanomagnet-based removal of lead and digoxin from living rats
Published in Nanoscale (21-09-2013)“…In a number of clinical conditions such as intoxication, bacteraemia or autoimmune diseases the removal of the disease-causing factor from blood would be the…”
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Clinical concentrations of morphine are cytotoxic on proliferating human fibroblasts in vitro
Published in European journal of anaesthesiology (01-11-2016)“…BACKGROUNDMorphine and other opioids are routinely used systemically and as wound infusions in the postoperative period. Their effect on wound and fracture…”
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Iron core/shell nanoparticles as magnetic drug carriers: possible interactions with the vascular compartment
Published in Nanomedicine (London, England) (01-09-2011)“…Nanomagnets with metal cores have recently been shown to be promising candidates for magnetic drug delivery due to higher magnetic moments compared with…”
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Modulation of Early Inflammatory Response by Different Balanced and Non-Balanced Colloids and Crystalloids in a Rodent Model of Endotoxemia: e93863
Published in PloS one (01-04-2014)“…The use of hydroxyethyl starch (HES) in sepsis has been shown to increase mortality and acute kidney injury. However, the knowledge of the exact mechanism by…”
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Nanoparticles: Endotoxin Removal by Magnetic Separation-Based Blood Purification (Adv. Healthcare Mater. 6/2013)
Published in Advanced healthcare materials (01-06-2013)“…Magnetic separation‐based blood purification enables rapid and selective removal of endotoxin and bacteria from human whole blood. Functional assays assessing…”
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