Search Results - "HASHIMOTO, Yoshiyuki"
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Preparation and Properties of Ball-Milled MgH2/Al Nanocomposites for Hydrogen Storage
Published in MATERIALS TRANSACTIONS (2014)“…For reversible hydrogen storage properties of 17MgH2 + 12Al ↔ Mg17Al12 + 17H2, MgH2/Al nanocomposites (I)–(IV) synthesized by ball milling of MgH2 and Al (or…”
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Production and characterization of highly tumor‐specific rat monoclonal antibodies recognizing the extracellular domain of human l‐type amino‐acid transporter 1
Published in Cancer science (01-05-2008)“…l‐type large amino acid transporter (LAT) 1, the first light chain (lc) of cluster of differentiation 98 (CD98) to be identified, is associated with the heavy…”
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Oncogenicity of L-type amino-acid transporter 1 (LAT1) revealed by targeted gene disruption in chicken DT40 cells: LAT1 is a promising molecular target for human cancer therapy
Published in Biochemical and biophysical research communications (25-03-2011)“…► We established LAT1 amino-acid transporter-disrupted DT40 cells. ► LAT1-disrupted cells showed slow growth and lost the oncogenicity. ► siRNA and mAb…”
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Towards therapeutic antibodies to membrane oncoproteins by a robust strategy using rats immunized with transfectants expressing target molecules fused to green fluorescent protein
Published in Cancer science (01-01-2011)“…Cell‐surface molecules containing growth factor receptors, adhesion molecules and transporter proteins are often over‐expressed in various cancer cells, and…”
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NIH3T3 cells overexpressing CD98 heavy chain resist early G1 arrest and apoptosis induced by serum starvation
Published in Cancer science (01-08-2012)“…CD98 is a heterodimeric glycoprotein of 125‐kDa, which consists of a 90‐kDa heavy chain (hc) subunit and 35‐kDa to 55‐kDa light chain (lc) subunits. It is…”
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Anti-tumor effect against human cancer xenografts by a fully human monoclonal antibody to a variant 8-epitope of CD44R1 expressed on cancer stem cells
Published in PloS one (17-01-2012)“…CD44 is a major cellular receptor for hyaluronic acids. The stem structure of CD44 encoded by ten normal exons can be enlarged by ten variant exons (v1-v10) by…”
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Cell‐death‐inducing monoclonal antibodies raised against DT40 tumor cells: Identification of chicken transferrin receptor as a novel cell‐death receptor
Published in Cancer science (01-05-2008)“…We obtained unique cell‐death‐inducing monoclonal antibodies (mAbs) named D18 and D19 against chicken DT40 cells. D18 and D19 caused several signs of…”
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Physical and functional interactions between the transcription factor PU.1 and the coactivator CBP
Published in Oncogene (18-02-1999)“…Yeast two-hybrid system was employed to isolate novel proteins that physically interact with PU.1, a member of Ets family transcription factors. Sequence…”
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Examination of the Factors Predicting Gait Independence at Discharge of Convalescent Patients with Initial Stroke: The Importance of the Ability of Roll-over and Getting Up Movements
Published in Rigakuryoho Kagaku (2018)“…[Purpose] Factors related to gait independence at discharge were extracted from stroke patients’ information on admission to a rehabilitation ward in the…”
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Simultaneous induction of apoptotic, autophagic, and necrosis-like cell death by monoclonal antibodies recognizing chicken transferrin receptor
Published in Biochemical and biophysical research communications (21-03-2008)“…Programmed cell death (PCD) is categorized as apoptotic, autophagic, or necrosis-like. Although the possibility that plural (two or three) death signals could…”
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回復期脳卒中患者の歩行自立予測: 信号検出分析による臨床応用を目指した検討
Published in Rigaku ryoho kagaku (01-01-2018)Get full text
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回復期初発脳卒中片麻痺患者の退院時歩行自立を予測する因子の検討: 寝返り,起き上がりを含む動作能力の重要性について
Published in Rigaku ryoho kagaku (01-01-2018)“…〔目的〕回復期リハビリテーション病棟入院時情報から退院時歩行自立に関わる因子を抽出することとした. 〔対象〕初発の片側性テント上脳卒中患者143例(男性82例,女性61例,年齢69 ±…”
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The role of Ets family transcription factor PU.1 in hematopoietic cell differentiation, proliferation and apoptosis
Published in Cell death and differentiation (01-07-1999)“…The PU.1 gene encodes an Ets family transcription factor which controls expression of many B cell- and macrophage-specific genes. Expression of the gene is…”
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Malignant Transformation of NIH3T3 Cells by Overexpression of Early Lymphocyte Activation Antigen CD98
Published in Biochemical and biophysical research communications (07-09-1999)“…CD98, which forms a heterodimer of relative molecular mass (Mr) 125, 000, was originally identified as an early T cell activation antigen. It consists of a…”
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Enhanced tumorigenicity caused by truncation of the extracellular domain of GP125/CD98 heavy chain
Published in Oncogene (14-12-2000)“…GP125/CD98 is a heterodimeric 125-kDa glycoprotein, which consists of an 85-kDa heavy chain (hc) and a 40-kDa light chain (lc), and is strongly expressed on…”
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Molecular Structural and Functional Characterization of Tumor Suppressive Anti–ErbB-2 Monoclonal Antibody by Phage Display System
Published in Journal of biochemistry (Tokyo) (01-02-2003)“…To investigate the molecular structural and functional characteristics of tumor-suppressive anti–ErbB-2 monoclonal antibody (mAb) SER4, we performed mAb-gene…”
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Constitutive Expression of Cytochrome P450 Genes in Newly Established Rat Hepatic Cell Lines
Published in Journal of biochemistry (Tokyo) (01-06-2003)“…Two cultured cell lines, called Kan-R1 and Kan-R2, were established from rat hepatic cells by in vitro culture with a hepatocarcinogen,…”
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Phage Display Cloning and Characterization of Monoclonal Antibody Genes and Recombinant Fab Fragment against the CD98 Oncoprotein
Published in Cancer science (01-12-2001)“…The Fab gene of anti‐CD98 heavy chain (h.c.) monoclonal antibody (mAb) HBJ127 was cloned and expressed as a recombinant Fab (rFab) fragment by means of a phage…”
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Reduction of DNA Binding Activity of the GATA-1 Transcription Factor in the Apoptotic Process Induced by Overexpression of PU.1 in Murine Erythroleukemia Cells
Published in Experimental cell research (25-11-1998)“…Previously we have shown that overexpression of PU.1, an Ets family transcription factor, in murine erythroleukemia (MEL) cells results in apoptotic cell death…”
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脳卒中患者の歩行自立判定評価: 回復期リハビリテーション病棟におけるアセスメントシートの導入効果
Published in 理学療法科学 (2016)Get full text
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