Search Results - "HASHIMOTO, Shu"

Role of airway epithelial barrier dysfunction in pathogenesis of asthma by Gon, Yasuhiro, Hashimoto, Shu

“…Bronchial asthma is characterized by persistent cough, increased sputum, and repeated wheezing. The pathophysiology underlying these symptoms is the…”
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Asthma and COPD overlap pathophysiology of ACO by Hikichi, Mari, Hashimoto, Shu, Gon, Yasuhiro

“…Asthma and COPD appear as a result of different mechanisms triggered by different pathogeneses and although they present different features and symptoms of…”
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Hippo signaling disruption and Akt stimulation of ovarian follicles for infertility treatment by Kawamura, Kazuhiro, Cheng, Yuan, Suzuki, Nao, Deguchi, Masashi, Sato, Yorino, Takae, Seido, Ho, Chi-hong, Kawamura, Nanami, Tamura, Midori, Hashimoto, Shu, Sugishita, Yodo, Morimoto, Yoshiharu, Hosoi, Yoshihiko, yoshioka, Nobuhito, Ishizuka, Bunpei, Hsueh, Aaron J.

“…Primary ovarian insufficiency (POI) and polycystic ovarian syndrome are ovarian diseases causing infertility. Although there is no effective treatment for POI,…”
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Mural granulosa cells support to maintain the viability of growing porcine oocytes and its developmental competence after insemination by Yamochi, Takayuki, Hashimoto, Shu, Morimoto, Yoshiharu

“…Purpose To enhance the in vitro growth of porcine oocytes, we studied the effect of mural granulosa cells (MGCs) on the viability of oocytes attached to…”
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Mitochondrial function of human embryo: Decline in their quality with maternal aging by Hashimoto, Shu, Morimoto, Yoshiharu

“…Background Female fertility declines with age, due to increased chromosomal aneuploidy and possible reduced mitochondrial function in the embryo. Methods This…”
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Selection of high-potential embryos by culture in poly(dimethylsiloxane) microwells and time-lapse imaging by Hashimoto, Shu, Ph.D, Kato, Nobuhiro, Ph.D, Saeki, Kazuhiro, Ph.D, Morimoto, Yoshiharu, M.D., Ph.D

“…Objective To assess the developmental kinetics of human embryos and their ability to develop to morphologically normal blastocysts. Design Experimental study…”
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Asthma and Chronic Obstructive Pulmonary Disease Overlap According to the Japanese Respiratory Society Diagnostic Criteria: The Prospective, Observational ACO Japan Cohort Study by Hashimoto, Shu, Sorimachi, Ryoko, Jinnai, Tatsunori, Ichinose, Masakazu

“…Introduction Patients with asthma-chronic obstructive pulmonary disease (COPD) overlap (ACO) present with chronic respiratory symptoms with features of both…”
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Prc1-rich kinetochores are required for error-free acentrosomal spindle bipolarization during meiosis I in mouse oocytes by Yoshida, Shuhei, Nishiyama, Sui, Lister, Lisa, Hashimoto, Shu, Mishina, Tappei, Courtois, Aurélien, Kyogoku, Hirohisa, Abe, Takaya, Shiraishi, Aki, Choudhary, Meenakshi, Nakaoka, Yoshiharu, Herbert, Mary, Kitajima, Tomoya S.

“…Acentrosomal meiosis in oocytes represents a gametogenic challenge, requiring spindle bipolarization without predefined bipolar cues. While much is known about…”
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69 : Decline in Mitochondrial Function of Human Embryo with Maternal Aging by Hashimoto, Shu, Morimoto, Yoshiharu

“…Background and Aims: Female fertility declines with age, due to increased chromosomal aneuploidy and possible reduced mitochondrial function in the embryo…”
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Effects of time-restricted feeding and type of food on fertility competence in female mice by Konishi, Nafuko, Matsumoto, Hiroshi, Hashimoto, Shu, Gamage, Udayanga Sanath Kankanam, Tachibana, Daisuke, Fukuda, Aisaku, Morimoto, Yoshiharu, Koyama, Masayasu

“…We assessed the effects of feeding regimen (ad libitum vs. time-restricted food access) and type of food (normal chow (NC: 12% fat) vs. moderately high calorie…”
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Novel tri-specific tribodies induce strong T cell activation and anti-tumor effects in vitro and in vivo by Passariello, Margherita, Yoshioka, Asami, Takahashi, Kota, Hashimoto, Shu-ichi, Inoue, Toshikazu, Nakamura, Koji, De Lorenzo, Claudia

“…Background Immunotherapy based on Bi-specific T Cell Engagers (TCE) represents one of the most attractive strategy to treat cancers resistant to conventional…”
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Influence of climatic conditions in the mesothermal climate area on pregnancies following elective fresh single blastocyst transfer by Matsumoto, Hiroshi, Hashimoto, Shu, Mizuno, Satoshi, Fukuda, Aisaku, Morimoto, Yoshiharu

“…Purpose To investigate the effect of climatic parameters in the mesothermal climate area on clinical pregnancy and live birth following fresh single blastocyst…”
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Quantitative and qualitative changes of mitochondria in human preimplantation embryos by Hashimoto, Shu, Morimoto, Naoharu, Yamanaka, Masaya, Matsumoto, Hiroshi, Yamochi, Takayuki, Goto, Hiroya, Inoue, Masayasu, Nakaoka, Yoshiharu, Shibahara, Hiroaki, Morimoto, Yoshiharu

“…Purpose The oxygen consumption rates (OCRs) in mice and cattle have been reported to change during preimplantation embryogenesis. On the other hand,…”
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Combined assessment of serum eosinophil-derived neurotoxin and YKL-40 may identify Asthma-COPD overlap by Shirai, Toshihiro, Hirai, Keita, Gon, Yasuhiro, Maruoka, Shuichiro, Mizumura, Kenji, Hikichi, Mari, Itoh, Kunihiko, Hashimoto, Shu

“…Dear Editor, In our previous report, we showed that the combined assessment of serum periostin, a biomarker of type 2 inflammation in asthma, and serum YKL-40,…”
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Effect of X-ray exposure during hysterosalpingography on capabilities of female germ cells by Matsumoto, Hiroshi, Fukuda, Aisaku, Mizuno, Satoshi, Hashimoto, Shu, Morimoto, Yoshiharu

“…Purpose To elucidate the effect of X-ray exposure during hysterosalpingography (HSG) on subsequent laboratory outcomes in in vitro fertilization (IVF). Methods…”
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Streamlined human antibody generation and optimization by exploiting designed immunoglobulin loci in a B cell line by Seo, Hidetaka, Masuda, Hitomi, Asagoshi, Kenjiro, Uchiki, Tomoaki, Kawata, Shigehisa, Sasaki, Goh, Yabuki, Takashi, Miyai, Shunsuke, Takahashi, Naoki, Hashimoto, Shu-ichi, Sawada, Atsushi, Takaiwa, Aki, Koyama, Chika, Tamai, Kanako, Kurosawa, Kohei, Lin, Ke-Yi, Ohta, Kunihiro, Nakazaki, Yukoh

“…Monoclonal antibodies (mAbs) are widely utilized as therapeutic drugs for various diseases, such as cancer, autoimmune diseases, and infectious diseases. Using…”
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Mitochondrial Transfer into Human Oocytes Improved Embryo Quality and Clinical Outcomes in Recurrent Pregnancy Failure Cases by Morimoto, Yoshiharu, Gamage, Udayanga Sanath Kankanam, Yamochi, Takayuki, Saeki, Noriatsu, Morimoto, Naoharu, Yamanaka, Masaya, Koike, Akiko, Miyamoto, Yuki, Tanaka, Kumiko, Fukuda, Aisaku, Hashimoto, Shu, Yanagimachi, Ryuzo

“…One of the most critical issues to be solved in reproductive medicine is the treatment of patients with multiple failures of assisted reproductive treatment…”
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Our future: Experiencing the coronavirus disease 2019 (COVID-19) outbreak and pandemic by Hashimoto, Shu, Hikichi, Mari, Maruoka, Shuichiro, Gon, Yasuhiro

“…Outbreaks of the novel coronavirus disease (severe acute respiratory syndrome coronavirus 2: SARS-CoV-2) (coronavirus disease 2019; COVID-19) remind us once…”
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Exploring the Impact of Endometrioma Aspiration and Dienogest Combination Therapy on Cyst Size, Inflammatory Cytokines in Follicular Fluid and Fertility Outcomes by Shigeta, Mamoru, Tsuji, Isao, Hashimoto, Shu, Kankanam Gamage, Udayanga Sanath, Yamanaka, Masaya, Fukuda, Aisaku, Morimoto, Yoshiharu, Tachibana, Daisuke

“…Endometriomas (chocolate cysts) are cystic lesions that can develop on ovaries, and are characterized by the presence of ectopic endometrial tissue or similar…”
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Mitochondrial function in immature bovine oocytes is improved by an increase of cellular cyclic AMP by Hashimoto, Shu, Yamanaka, Masaya, Yamochi, Takayuki, Iwata, Hisataka, Kawahara-Miki, Ryouka, Inoue, Masayasu, Morimoto, Yoshiharu

“…Although in vitro maturation (IVM) of oocytes is important for assisted reproduction, the rate of development of embryos from IVM oocytes is lower than from…”
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