Search Results - "HASHIDA, Shinsuke"

Lymphangioleiomyomatosis:Rapidly Progressive Retroperitoneal Cystic Tumor Mimicking Malignancy by Hamada, Noboru, Hashida, Shinsuke, Okawa, Sachi, Suwaki, Toshimitsu

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A case of infective endocarditis mimicking a large mesenteric abscess by Yokota, Kyoko, Sakamoto, Asuna, Takatsu, Fumiaki, Hashida, Shinsuke

“…Infective endocarditis (IE) demonstrates a broad array of clinical presentations and complications. However, IE with prominent abdominal findings is uncommon…”
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Antitumor effect of afatinib, as a human epidermal growth factor receptor 2‐targeted therapy, in lung cancers harboring HER2 oncogene alterations by Suzawa, Ken, Toyooka, Shinichi, Sakaguchi, Masakiyo, Morita, Mizuki, Yamamoto, Hiromasa, Tomida, Shuta, Ohtsuka, Tomoaki, Watanabe, Mototsugu, Hashida, Shinsuke, Maki, Yuho, Soh, Junichi, Asano, Hiroaki, Tsukuda, Kazunori, Miyoshi, Shinichiro

“…Human epidermal growth factor receptor 2 (HER2) is a member of the HER family of proteins containing four receptor tyrosine kinases. It plays an important role…”
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Novel Germline Mutation in the Transmembrane Domain of HER2 in Familial Lung Adenocarcinomas by YAMAMOTO, Hiromasa, HIGASA, Koichiro, MATSUO, Keitaro, KIURA, Katsuyuki, MIYOSHI, Shinichiro, MATSUDA, Fumihiko, TOYOOKA, Shinichi, SAKAGUCHI, Masakiyo, SHIEN, Kazuhiko, SOH, Junichi, ICHIMURA, Koichi, FURUKAWA, Masashi, HASHIDA, Shinsuke, TSUKUDA, Kazunori, TAKIGAWA, Nagio

“…We encountered a family of Japanese descent in which multiple members developed lung cancer. Using whole-exome sequencing, we identified a novel germline…”
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Targeting the miR-200c/LIN28B axis in acquired EGFR-TKI resistance non-small cell lung cancer cells harboring EMT features by Sato, Hiroki, Shien, Kazuhiko, Tomida, Shuta, Okayasu, Kazuhiro, Suzawa, Ken, Hashida, Shinsuke, Torigoe, Hidejiro, Watanabe, Mototsugu, Yamamoto, Hiromasa, Soh, Junichi, Asano, Hiroaki, Tsukuda, Kazunori, Miyoshi, Shinichiro, Toyooka, Shinichi

“…MicroRNA (miR)-200 family members (miR-200s) are frequently silenced in advanced cancer and have been implicated in the process of epithelial-to-mesenchymal…”
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Acquisition of cancer stem cell‐like properties in non‐small cell lung cancer with acquired resistance to afatinib by Hashida, Shinsuke, Yamamoto, Hiromasa, Shien, Kazuhiko, Miyoshi, Yuichiro, Ohtsuka, Tomoaki, Suzawa, Ken, Watanabe, Mototsugu, Maki, Yuho, Soh, Junichi, Asano, Hiroaki, Tsukuda, Kazunori, Miyoshi, Shinichiro, Toyooka, Shinichi

“…Afatinib is an irreversible epidermal growth factor receptor (EGFR)‐tyrosine kinase inhibitor (TKI) that is known to be effective against the EGFR T790M…”
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Efficacy and Safety of Ramucirumab/nab-paclitaxel for Previously Treated Advanced Gastric Cancer in Community Hospitals by Hashida, Shinsuke, Tanaka, Norimitsu, Takahashi, Yuta, Onoda, Yuji, Colvin, Hugh Shunsuke, Ohashi, Ryuichiro, Okamoto, Kunio

“…As the nanoparticle albumin-bound paclitaxel (nab-PTX) is free of ethanol and premedication, the duration of administration is shorter and patients can drive…”
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Estimation of age-related DNA degradation from formalin-fixed and paraffin-embedded tissue according to the extraction methods by Watanabe, Mototsugu, Hashida, Shinsuke, Yamamoto, Hiromasa, Matsubara, Takehiro, Ohtsuka, Tomoaki, Suzawa, Ken, Maki, Yuho, Soh, Junichi, Asano, Hiroaki, Tsukuda, Kazunori, Toyooka, Shinichi, Miyoshi, Shinichiro

“…Techniques for the extraction and use of nucleic acids from formalin-fixed and paraffin-embedded (FFPE) tissues, preserved over long time periods in libraries,…”
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Downregulation of TBXAS1 in an iron‐induced malignant mesothelioma model by Minami, Daisuke, Takigawa, Nagio, Kato, Yuka, Kudo, Kenichiro, Isozaki, Hideko, Hashida, Shinsuke, Harada, Daijiro, Ochi, Nobuaki, Fujii, Masanori, Kubo, Toshio, Ohashi, Kadoaki, Sato, Akiko, Tanaka, Takehiro, Hotta, Katsuyuki, Tabata, Masahiro, Toyooka, Shinichi, Tanimoto, Mitsune, Kiura, Katsuyuki

“…Malignant mesothelioma is an aggressive and therapy‐resistant neoplasm arising from mesothelial cells. Evidence suggests that the major pathology associated…”
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Interaction of cytokeratin 19 head domain and HER2 in the cytoplasm leads to activation of HER2-Erk pathway by Ohtsuka, Tomoaki, Sakaguchi, Masakiyo, Yamamoto, Hiromasa, Tomida, Shuta, Takata, Katsuyoshi, Shien, Kazuhiko, Hashida, Shinsuke, Miyata-Takata, Tomoko, Watanabe, Mototsugu, Suzawa, Ken, Soh, Junichi, Youyi, Chen, Sato, Hiroki, Namba, Kei, Torigoe, Hidejiro, Tsukuda, Kazunori, Yoshino, Tadashi, Miyoshi, Shinichiro, Toyooka, Shinichi

“…HER2 is a receptor tyrosine kinase and its upregulation via activating mutations or amplification has been identified in some malignant tumors, including lung…”
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Distant Bystander Effect of REIC/DKK3 Gene Therapy Through Immune System Stimulation in Thoracic Malignancies by Suzawa, Ken, Shien, Kazuhiko, Peng, Huang, Sakaguchi, Masakiyo, Watanabe, Masami, Hashida, Shinsuke, Maki, Yuho, Yamamoto, Hiromasa, Tomida, Shuta, Soh, Junichi, Asano, Hiroaki, Tsukuda, Kazunori, Nasu, Yasutomo, Kumon, Hiromi, Miyoshi, Shinichiro, Toyooka, Shinichi

“…Reduced expression in immortalized cell (REIC)/Dickkoph-3 (DKK3) is a tumor-suppressor gene, and its overexpression by adenovirus vector (Ad-REIC) exhibits a…”
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Optimal method for quantitative detection of plasma EGFR T790M mutation using droplet digital PCR system by Suzawa, Ken, Yamamoto, Hiromasa, Ohashi, Kadoaki, Hashida, Shinsuke, Tomida, Shuta, Kubo, Toshio, Maki, Yuho, Soh, Junichi, Tsukuda, Kazunori, Kiura, Katsuyuki, Miyoshi, Shinichiro, Toyooka, Shinichi

“…Though patients with EGFR mutations are initially responsive to EGFR-tyrosine kinase inhibitors (TKIs), most tumors ultimately acquire resistance to EGFR-TKIs…”
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A new human lung adenocarcinoma cell line harboring the EML4-ALK fusion gene by Isozaki, Hideko, Yasugi, Masayuki, Takigawa, Nagio, Hotta, Katsuyuki, Ichihara, Eiki, Taniguchi, Akihiko, Toyooka, Shinichi, Hashida, Shinsuke, Sendo, Toshiaki, Tanimoto, Mitsune, Kiura, Katsuyuki

“…The echinoderm microtubule associated protein-like 4 (EML4)-anaplastic lymphoma kinase (ALK) fusion gene was identified in patients with non-small cell lung…”
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Primary pulmonary melanoma: a report of two cases by Watanabe, Mototsugu, Yamamoto, Hiromasa, Hashida, Shinsuke, Soh, Junichi, Sugimoto, Seiichiro, Toyooka, Shinichi, Miyoshi, Shinichiro

“…Malignant melanoma is a refractory malignancy with a dismal prognosis. It generally arises from the skin in most cases, and cases of primary pulmonary…”
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Acquired Resistance to EGFR Inhibitors Is Associated with a Manifestation of Stem Cell-like Properties in Cancer Cells by SHIEN, Kazuhiko, TOYOOKA, Shinichi, TSUKUDA, Kazunori, TAKIGAWA, Nagio, KIURA, Katsuyuki, GAZDAR, Adi F, LAM, Wan L, MIYOSHI, Shinichiro, YAMAMOTO, Hiromasa, SOH, Junichi, JIDA, Masaru, THU, Kelsie L, HASHIDA, Shinsuke, MAKI, Yuho, ICHIHARA, Eiki, ASANO, Hiroaki

“…Acquired resistance to EGF receptor (EGFR) tyrosine kinase inhibitor (TKI) is a critical problem in the treatment of lung cancer. Although several mechanisms…”
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Donor-derived cell-free DNA is associated with acute rejection and decreased oxygenation in primary graft dysfunction after living donor-lobar lung transplantation by Tanaka, Shin, Sugimoto, Seiichiro, Kurosaki, Takeshi, Miyoshi, Kentaroh, Otani, Shinji, Suzawa, Ken, Hashida, Shinsuke, Yamane, Masaomi, Oto, Takahiro, Toyooka, Shinichi

“…Donor-derived cell-free DNA (dd-cf-DNA) has been shown to be an informative biomarker of rejection after lung transplantation (LT) from deceased donors…”
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Two cases of strangulated bowel obstruction due to exposed vessel and nerve after laparoscopic and robot-assisted lateral lymph node dissection (LLND) for rectal cancer by Fujiwara, Ryota, Yano, Masaaki, Matsumoto, Makoto, Higashihara, Tomoaki, Tsudaka, Shimpei, Hashida, Shinsuke, Ichihara, Shuji, Otani, Hiroki

“…Background The majority of small bowel obstructions (SBO) are caused by adhesion due to abdominal surgery. Internal hernias, a very rare cause of SBO, can…”
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A case of recurrent breast cancer with multiple lung metastases responding to anastrozole monotherapy by Maruyama, Shuichiro, Ito, Maiko, Hirano, Yutaka, Shimo, Toshiro, Hashida, Shinsuke, Iga, Korechika, Inukai, Michio, Kanaya, Yoshiaki, Yokoyama, Nobuji

“…A 51-year-old postmenopausal woman was referred to our hospital for treatment of ER-positive recurrent breast cancer. The patient had lung and pleural…”
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The degree of microRNA-34b/c methylation in serum-circulating DNA is associated with malignant pleural mesothelioma by Muraoka, Takayuki, Soh, Junichi, Toyooka, Shinichi, Aoe, Keisuke, Fujimoto, Nobukazu, Hashida, Shinsuke, Maki, Yuho, Tanaka, Norimitsu, Shien, Kazuhiko, Furukawa, Masashi, Yamamoto, Hiromasa, Asano, Hiroaki, Tsukuda, Kazunori, Kishimoto, Takumi, Otsuki, Takemi, Miyoshi, Shinichiro

“…Abstract Objectives Malignant pleural mesothelioma (MPM) is an aggressive tumor with a poor prognosis. microRNA-34b/c (miR-34b/c), which plays an important…”
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Hsp90 inhibitor NVP-AUY922 enhances the radiation sensitivity of lung cancer cell lines with acquired resistance to EGFR-tyrosine kinase inhibitors by HASHIDA, SHINSUKE, YAMAMOTO, HIROMASA, SHIEN, KAZUHIKO, OHTSUKA, TOMOAKI, SUZAWA, KEN, MAKI, YUHO, FURUKAWA, MASASHI, SOH, JUNICHI, ASANO, HIROAKI, TSUKUDA, KAZUNORI, MIYOSHI, SHINICHIRO, KANAZAWA, SUSUMU, TOYOOKA, SHINICHI

“…Acquired resistance to epidermal growth factor receptor (EGFR)-tyrosine kinase inhibitors (TKIs) is a critical issue that needs to be overcome in the treatment…”
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